Y Kudo

Summary

Affiliation: Hiroshima University
Country: Japan

Publications

  1. ncbi request reprint Reduced expression of p27(Kip1) correlates with an early stage of cancer invasion in oral squamous cell carcinoma
    Y Kudo
    Department of Oral Pathology, Hiroshima University, Faculty of Dentistry, Hiroshima, Japan
    Cancer Lett 151:217-22. 2000
  2. ncbi request reprint VEGF-C is associated with lymphatic status and invasion in oral cancer
    B S M S Siriwardena
    Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Clin Pathol 61:103-8. 2008
  3. ncbi request reprint Clinical and histopathological analyses of desmoplastic ameloblastoma
    T Takata
    Department of Oral Pathology, Hiroshima University School of Dentistry, Japan
    Pathol Res Pract 195:669-75. 1999
  4. ncbi request reprint High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas
    Y Kudo
    Department of Oral Pathology, Hiroshima University, Faculty of Dentistry, Hiroshima 734-8553, Japan
    Cancer Res 61:7044-7. 2001
  5. ncbi request reprint Inhibition of CD44v9 upregulates the invasion ability of oral squamous cell carcinoma cells
    S Sato
    Department of Oral Pathology, Hiroshima University, Faculty of Dentistry, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8553, Japan
    Oral Oncol 39:27-30. 2003
  6. ncbi request reprint Cytokine expression in rat molar gingival periodontal tissues after topical application of lipopolysaccharide
    M Miyauchi
    Department of Oral Pathology, Hiroshima University Faculty of Dentistry, 1 2 3, Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Histochem Cell Biol 116:57-62. 2001
  7. ncbi request reprint Periostin: novel diagnostic and therapeutic target for cancer
    Y Kudo
    Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Histol Histopathol 22:1167-74. 2007
  8. ncbi request reprint So-called 'hybrid' lesion of desmoplastic and conventional ameloblastoma: report of a case and review of the literature
    T Takata
    Department of Oral Pathology, Hiroshima University School of Dentistry, Hiroshima, Japan
    Pathol Int 49:1014-8. 1999
  9. doi request reprint Aberrant beta-catenin expression and adenomatous polyposis coli gene mutation in ameloblastoma and odontogenic carcinoma
    B S M S Siriwardena
    Department of Oral Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8553, Japan
    Oral Oncol 45:103-8. 2009
  10. ncbi request reprint Immunoexpression of transforming growth factor beta in desmoplastic ameloblastoma
    T Takata
    Department of Oral Pathology, Hiroshima University School of Dentistry, Japan
    Virchows Arch 436:319-23. 2000

Detail Information

Publications41

  1. ncbi request reprint Reduced expression of p27(Kip1) correlates with an early stage of cancer invasion in oral squamous cell carcinoma
    Y Kudo
    Department of Oral Pathology, Hiroshima University, Faculty of Dentistry, Hiroshima, Japan
    Cancer Lett 151:217-22. 2000
    ..Reduced expression of p27(Kip1) may concern the cancer invasion directly or indirectly as well as abnormal proliferation...
  2. ncbi request reprint VEGF-C is associated with lymphatic status and invasion in oral cancer
    B S M S Siriwardena
    Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Clin Pathol 61:103-8. 2008
    ..Recently, it has been revealed that lymphangiogenic growth factor VEGF-C and its receptor Flt-4 play an important role for invasion and metastasis in cancer cells...
  3. ncbi request reprint Clinical and histopathological analyses of desmoplastic ameloblastoma
    T Takata
    Department of Oral Pathology, Hiroshima University School of Dentistry, Japan
    Pathol Res Pract 195:669-75. 1999
    ..There was no capsule formation. Recurrence rate was 14% in DA and 20% in non-DA. The present study based on data of DA in the Japanese population supports that DA must be considered as a distinct clinicopathologic entity...
  4. ncbi request reprint High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas
    Y Kudo
    Department of Oral Pathology, Hiroshima University, Faculty of Dentistry, Hiroshima 734-8553, Japan
    Cancer Res 61:7044-7. 2001
    ....
  5. ncbi request reprint Inhibition of CD44v9 upregulates the invasion ability of oral squamous cell carcinoma cells
    S Sato
    Department of Oral Pathology, Hiroshima University, Faculty of Dentistry, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8553, Japan
    Oral Oncol 39:27-30. 2003
    ..It may ultimately promote the establishment of a metastatic lesion...
  6. ncbi request reprint Cytokine expression in rat molar gingival periodontal tissues after topical application of lipopolysaccharide
    M Miyauchi
    Department of Oral Pathology, Hiroshima University Faculty of Dentistry, 1 2 3, Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Histochem Cell Biol 116:57-62. 2001
    ....
  7. ncbi request reprint Periostin: novel diagnostic and therapeutic target for cancer
    Y Kudo
    Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Histol Histopathol 22:1167-74. 2007
    ..This review summarizes the recent understanding of Periostin roles in tumor development and speculates on the usefulness of Periostin as a therapeutic and diagnostic target for cancer...
  8. ncbi request reprint So-called 'hybrid' lesion of desmoplastic and conventional ameloblastoma: report of a case and review of the literature
    T Takata
    Department of Oral Pathology, Hiroshima University School of Dentistry, Hiroshima, Japan
    Pathol Int 49:1014-8. 1999
    ..Many more cases of 'hybrid' lesion are needed to clarify the clinicopathological, histopathological and biological characteristics of this interesting variant of ameloblastoma...
  9. doi request reprint Aberrant beta-catenin expression and adenomatous polyposis coli gene mutation in ameloblastoma and odontogenic carcinoma
    B S M S Siriwardena
    Department of Oral Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8553, Japan
    Oral Oncol 45:103-8. 2009
    ..Our findings suggest that aberrant beta-catenin expression and APC missense mutation may play an important role for the pathogenesis of epithelial odontogenic tumors...
  10. ncbi request reprint Immunoexpression of transforming growth factor beta in desmoplastic ameloblastoma
    T Takata
    Department of Oral Pathology, Hiroshima University School of Dentistry, Japan
    Virchows Arch 436:319-23. 2000
    ..In the "hybrid" lesion, TGF-beta was not expressed in the area of follicular ameloblastoma but in that of DA. These results show that TGF-beta produced by tumor cells of DA plays a part in the desmoplastic matrix formation...
  11. doi request reprint Establishment of mesenchymal cell line derived from human developing odontoma
    H Hatano
    Department of Oral and Maxillofacial Surgery, Division of Cervico Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Oral Dis 18:756-62. 2012
    ..These are commonly found in tooth-bearing regions, although the etiology remains unknown. There are no previous reports of an established line of immortalized human odontoma cells...
  12. ncbi request reprint Immuno-localization of COX-1 and COX-2 in the rat molar periodontal tissue after topical application of lipopolysaccharide
    M Miyauchi
    Division of Frontier Biomedical Science, Department of Oral Maxillofacial Pathobiology, Graduate School of Biomedical Sciences, Hiroshima University, 734 8553, Japan
    Arch Oral Biol 49:739-46. 2004
    ..It is suggested that the inducible production of PGE2 via COX-2 by these cells may be associated with connective tissue destruction and alveolar bone resorption...
  13. pmc Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer
    B S M S Siriwardena
    Department of Oral Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Hiroshima, Japan
    Br J Cancer 95:1396-403. 2006
    ..In summary, these findings suggest that Periostin may promote invasion and angiogenesis in OSCC, and that Periostin can be a strong marker for prediction of metastasis in oral cancer patients...
  14. pmc The FGFR1 inhibitor PD173074 induces mesenchymal-epithelial transition through the transcription factor AP-1
    P T Nguyen
    Department of Oral and Maxillofacial Pathobiology, Division of Frontier Medical Science, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Br J Cancer 109:2248-58. 2013
    ..Fibroblast growth factor receptor 1 is an oncoprotein that is involved in tumorigenesis, and PD173074 is known to be a selective inhibitor of FGFR1. However, the roles of FGFR1 and FGFR1 inhibitors have not yet been examined in detail...
  15. ncbi request reprint Immunohistochemical demonstration of an enamel sheath protein, sheathlin, in odontogenic tumors
    T Takata
    Department of Oral Pathology, Hiroshima University School of Dentistry, Japan
    Virchows Arch 436:324-9. 2000
    ....
  16. ncbi request reprint Establishment of human cementifying fibroma cell lines by transfection with temperature-sensitive simian virus-40 T-antigen gene and hTERT gene
    Y Kudo
    Department of Oral Pathology, Faculty of Dentistry, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Bone 30:712-7. 2002
    ....
  17. ncbi request reprint Diagnostic performance of general dental practitioners after lecture in identifying post-menopausal women with low bone mineral density by panoramic radiographs
    P Sutthiprapaporn
    Department of Oral and Maxillofacial Radiology, Division of Medical Intelligence and Informatics, Hiroshima University, Hiroshima, Japan
    Dentomaxillofac Radiol 35:249-52. 2006
    ....
  18. ncbi request reprint Identification of post-menopausal women at risk of osteoporosis by trained general dental practitioners using panoramic radiographs
    A Taguchi
    Department of Oral and Maxillofacial Radiology, Hiroshima University Hospital, 1 2 3 Kasumi Minami ku, Hiroshima 734 8553, Japan
    Dentomaxillofac Radiol 36:149-54. 2007
    ..The purpose of this study was to assess whether trained general dental practitioners (GDPs) can identify post-menopausal women with undetected low skeletal BMD as well as spinal fractures by panoramic radiographs in their clinics...
  19. ncbi request reprint Computer-aided system for measuring the mandibular cortical width on dental panoramic radiographs in identifying postmenopausal women with low bone mineral density
    A Z Arifin
    Department of Information Engineering, Graduate School of Engineering, Hiroshima University, and Department of Oral and Maxillofacial Radiology, Hiroshima University Hospital, Higashi Hiroshima, Japan
    Osteoporos Int 17:753-9. 2006
    ..The purposes of this study were to develop a computer-aided system for measuring mandibular cortical width on dental panoramic radiographs and clarify the diagnostic efficacy of this system...
  20. ncbi request reprint Risk of vertebral osteoporosis in post-menopausal women with alterations of the mandible
    A Taguchi
    Department of Oral and Maxillofacial Radiology, Hiroshima University Hospital, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Dentomaxillofac Radiol 36:143-8. 2007
    ..However, those studies did not estimate the multivariate-adjusted risk for low vertebral BMD or osteoporosis associated with alterations of the mandible...
  21. ncbi request reprint Observer performance in diagnosing osteoporosis by dental panoramic radiographs: results from the osteoporosis screening project in dentistry (OSPD)
    A Taguchi
    Department of Oral and Maxillofacial Radiology, Hiroshima University Hospital, Hiroshima, Japan
    Bone 43:209-13. 2008
    ..Information gathered from radiographic examination is at least as useful as that gathered from the OST index...
  22. ncbi request reprint An analysis using DNA microarray of the time course of gene expression during syncytialization of a human placental cell line (BeWo)
    Y Kudo
    Department of Human Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK
    Placenta 25:479-88. 2004
    ..Further analysis of this data and expression profiling in general will be able to contribute to understanding the functional basis for the formation of the placental syncytiotrophoblast...
  23. doi request reprint A computer-aided diagnosis system to screen for osteoporosis using dental panoramic radiographs
    T Nakamoto
    Department of Oral and Maxillofacial Radiology Division of Medical Intelligence and Informatics, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8553, Japan
    Dentomaxillofac Radiol 37:274-81. 2008
    ..The purposes of this study were to develop a computer-aided diagnosis (CAD) system that automatically determines cortical erosion of the mandible on dental panoramic radiographs and to assess the validation of this CAD system...
  24. ncbi request reprint Changes in expression and function of syncytin and its receptor, amino acid transport system B(0) (ASCT2), in human placental choriocarcinoma BeWo cells during syncytialization
    Y Kudo
    Department of Human Anatomy and Genetics, University of Oxford, Oxford, UK
    Placenta 23:536-41. 2002
    ....
  25. ncbi request reprint Diagnostic efficacy of alveolar bone loss of the mandible for identifying postmenopausal women with femoral osteoporosis
    K Ishii
    Department of Oral and Maxillofacial Radiology, Hiroshima University Hospital, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Dentomaxillofac Radiol 36:28-33. 2007
    ..The purpose of this study was to evaluate whether ABL of the mandible on panoramic radiographs is useful for identifying femoral osteoporosis in postmenopausal women in comparison with MCW...
  26. ncbi request reprint Heterodimeric amino acid transporters in the placenta--a workshop report
    T R H Regnault
    Department of Obstetrics and Gynaecology, University of Western Ontario, London, Ontario Canada
    Placenta 28:S103-6. 2007
  27. ncbi request reprint Codon usage and tRNA genes in eukaryotes: correlation of codon usage diversity with translation efficiency and with CG-dinucleotide usage as assessed by multivariate analysis
    S Kanaya
    Department of Bio-System Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Yamagata-ken 992-8510, Japan
    J Mol Evol 53:290-8. 2001
    ....
  28. ncbi request reprint Survivin, a potential early predictor of tumor progression in the oral mucosa
    L Lo Muzio
    Institute of Dental Sciences, Faculty of Medicine, University of Ancona, Ancona, Italy
    J Dent Res 82:923-8. 2003
    ..High expression of cytoplasmic/nuclear survivin is an early event during oral carcinogenesis and may provide a useful tool for the identification of precancerous lesions at higher risk of progression into invasive carcinoma...
  29. ncbi request reprint Cellular localization of thrombopoietin mRNA in the liver by in situ hybridization
    S Nomura
    Pharmaceutical Research Laboratory, Kirin Brewery Co, Ltd, Gunma, Japan
    Exp Hematol 25:565-72. 1997
    ..These results clearly demonstrate that hepatocytes are the primary site of TPO production in the liver from fetus to adult...
  30. ncbi request reprint Binding assay of low density lipoprotein to Asp-hemolysin from Aspergillus fumigatus
    Y Fukuchi
    Japanese Red Cross Sendai Hospital, Japan
    Biol Pharm Bull 19:1380-1. 1996
    ..LDL binds to Asp-hemolysin with an affinity as high as the LDL receptor. The apparent Kd, determined by Scatchard plot analysis, was 8.9 x 10(-9) M [125I]LDL. Asp-hemolysin is thus identified as a novel LDL-binding protein...
  31. ncbi request reprint Growth factors and trophoblast differentiation--workshop report
    D W Morrish
    Department of Medicine, University of Alberta, 362 Heritage Medical Research Centre, Edmonton, Alberta T6G 2S2, Canada
    Placenta 28:S121-4. 2007
  32. ncbi request reprint Alleic variants of human melatonin 1a receptor: function and prevalence in subjects with circadian rhythm sleep disorders
    T Ebisawa
    Department of Psychiatry, Saitama Medical School, Saitama, Japan
    Biochem Biophys Res Commun 262:832-7. 1999
    ....
  33. ncbi request reprint A study of L-leucine, L-phenylalanine and L-alanine transport in the perfused rat mammary gland: possible involvement of LAT1 and LAT2
    D B Shennan
    Hannah Research Institute, Ayr Scotland, UK
    Biochim Biophys Acta 1564:133-9. 2002
    ..The finding that L-alanine uptake by the gland was inhibited by BCH suggests that LAT2 may make a significant contribution to neutral amino acid uptake by the mammary epithelium...
  34. ncbi request reprint Analysis of codon usage diversity of bacterial genes with a self-organizing map (SOM): characterization of horizontally transferred genes with emphasis on the E. coli O157 genome
    S Kanaya
    Department of Bio-System Engineering, Faculty of Engineering, Yamagata University, Yonezawa, 992-8510, Yamagata-ken, Japan
    Gene 276:89-99. 2001
    ..We used SOM to examine codon usage heterogeneity in the E. coli O157 genome, which contains 'O157-unique segments' (O-islands), and showed that SOM is a powerful tool for characterization of horizontally transferred genes...
  35. pmc Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome
    T Ebisawa
    Department of Psychiatry, Saitama Medical School, 38 Morohongo, Saitama 350 0495, Japan
    EMBO Rep 2:342-6. 2001
    ..037; odds ratio = 7.79; 95% CI 1.59-38.3) in our study population. Our results suggest that structural polymorphisms in the hPer3 gene may be implicated in the pathogenesis of DSPS...
  36. ncbi request reprint [Two dimensional analysis of neural activities by calcium imaging]
    Y Kudo
    Mitsubishi Kasei Institute of Life Sciences, Tokyo
    No To Hattatsu 27:115-22. 1995
    ..Already more than ten years have passed since the first demonstration of a fluorescent Ca2+ indicator, quin 2, and the methods using such Ca2+ indicators become important in the field of experimental biology...
  37. ncbi request reprint Direct evidence for mutual interactions between perineuronal astrocytes and interneurons in the CA1 region of the rat hippocampus
    Y Yamazaki
    Department of Neurophysiology, Yamagata University School of Medicine, 2 2 2 Iida nishi, Yamagata 990 9585, Japan
    Neuroscience 134:791-802. 2005
    ..These results directly demonstrate the existence of bidirectional interactions between neurons and perineuronal astrocytes...
  38. ncbi request reprint A novel neuroprotective compound FR901459 with dual inhibition of calcineurin and cyclophilins
    H Uchino
    Department of Anesthesiology, Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan
    Acta Neurochir Suppl 96:157-62. 2006
    ..These findings shed light on the clinical application and development of new drugs for the treatment of ischemic damage in the brain as well as in the heart and liver...
  39. pmc Heterodimeric amino acid transporters: expression of heavy but not light chains of CD98 correlates with induction of amino acid transport systems in human placental trophoblast
    Y Kudo
    Department of Human Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK
    J Physiol 523:13-8. 2000
    ....
  40. ncbi request reprint Multiple inhibitory pathways for lipopolysaccharide- and pro-inflammatory cytokine-induced nitric oxide production in cultured astrocytes
    N Kozuka
    Laboratory of Cellular Neurobiology, School of Life Science, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, 192 0392 Tokyo, Japan
    Neuroscience 144:911-9. 2007
    ..Moreover, these mechanisms provide useful therapeutic targets for the treatment of neurodegenerative diseases...
  41. ncbi request reprint Purification and characterization of thrombopoietin
    T Kato
    Pharmaceutical Research Laboratory, Kirin Brewery Co, Ltd, Gunma
    J Biochem 118:229-36. 1995
    ..These results indicate that a thrombopoietic factor originally found in the irradiated rat plasma is a ligand for the rat c-Mpl...