Tomoya Kitayama

Summary

Affiliation: Hiroshima University
Country: Japan

Publications

  1. pmc Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice
    Tomoya Kitayama
    Department of Cellular and Molecular Pharmacology, Division of Basic Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Mol Pain 9:23. 2013
  2. ncbi request reprint [Eating disorders and central nervous system damage]
    Tomoya Kitayama
    Department of Dental Pharmacology, Division of Integrated Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3, Kasumi, Minami Ku, Hiroshima, 734 8553, Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 29:165-9. 2009
  3. doi request reprint Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice
    Katsuya Morita
    Department of Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences, Kasumi 1 2 3, Minami Ku, Hiroshima 734 8553, Japan
    J Pharmacol Exp Ther 326:633-45. 2008
  4. doi request reprint The regulation of glycine transporter GLYT1 is mainly mediated by protein kinase Calpha in C6 glioma cells
    Norimitsu Morioka
    Department of Dental Pharmacology, Hiroshima University Graduate School of Biomedical Sciences, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Neurochem Int 53:248-54. 2008
  5. doi request reprint Glycinergic mediation of tactile allodynia induced by platelet-activating factor (PAF) through glutamate-NO-cyclic GMP signalling in spinal cord in mice
    Katsuya Morita
    Department of Dental Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences, Kasumi 1 2 3, Minami Ku, Hiroshima 734 8553, Japan
    Pain 138:525-36. 2008
  6. ncbi request reprint Assessing an eating disorder induced by 6-OHDA and the possibility of nerve regeneration therapy by transplantation of neural progenitor cells in rats
    Tomoya Kitayama
    Department of Dental Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences 1 2 3 Kasumi, Mimami ku, Hiroshima, 734 8553 Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 27:109-16. 2007
  7. doi request reprint P2X(7) receptor stimulation in primary cultures of rat spinal microglia induces downregulation of the activity for glutamate transport
    Norimitsu Morioka
    Department of Dental Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan
    Glia 56:528-38. 2008
  8. pmc Palliation of bone cancer pain by antagonists of platelet-activating factor receptors
    Katsuya Morita
    Department of Pharmacology, Faculty of Nursing, Hiroshima Bunka Gakuen University, Hiroshima, Japan Cancer Pathophysiology, Division National Cancer Center Research Institute, Tokyo, Japan Department of Cell and Molecular Pharmacology, Division of Basic Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan
    PLoS ONE 9:e91746. 2014
  9. ncbi request reprint Cyclic ADP-ribose mediates formyl methionyl leucyl phenylalanine (fMLP)-induced intracellular Ca(2+) rise and migration of human neutrophils
    Katsuya Morita
    Department of Dental Pharmacology, Hiroshima University Graduate School of Biomedical Sciences, Japan
    J Pharmacol Sci 106:492-504. 2008
  10. ncbi request reprint Analgesic action of nicotine on tibial nerve transection (TNT)-induced mechanical allodynia through enhancement of the glycinergic inhibitory system in spinal cord
    Md Joynal Abdin
    Department of Dental Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Life Sci 80:9-16. 2006

Collaborators

Detail Information

Publications10

  1. pmc Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice
    Tomoya Kitayama
    Department of Cellular and Molecular Pharmacology, Division of Basic Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Mol Pain 9:23. 2013
    ..It has been reported that naive PRIP-1 knockout mice have hyperalgesic responses...
  2. ncbi request reprint [Eating disorders and central nervous system damage]
    Tomoya Kitayama
    Department of Dental Pharmacology, Division of Integrated Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3, Kasumi, Minami Ku, Hiroshima, 734 8553, Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 29:165-9. 2009
    ..Thus, these indicate that we require an understanding of neuropsychopharmacology for the development of new medical treatments for eating and swallowing disorders...
  3. doi request reprint Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice
    Katsuya Morita
    Department of Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences, Kasumi 1 2 3, Minami Ku, Hiroshima 734 8553, Japan
    J Pharmacol Exp Ther 326:633-45. 2008
    ..This may also provide important information for understanding the underlying molecular mechanisms of the development of neuropathic pain...
  4. doi request reprint The regulation of glycine transporter GLYT1 is mainly mediated by protein kinase Calpha in C6 glioma cells
    Norimitsu Morioka
    Department of Dental Pharmacology, Hiroshima University Graduate School of Biomedical Sciences, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Neurochem Int 53:248-54. 2008
    ..Together, these results suggest PKCalpha to be a crucial factor in the regulation of glycine transport in C6 cells...
  5. doi request reprint Glycinergic mediation of tactile allodynia induced by platelet-activating factor (PAF) through glutamate-NO-cyclic GMP signalling in spinal cord in mice
    Katsuya Morita
    Department of Dental Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences, Kasumi 1 2 3, Minami Ku, Hiroshima 734 8553, Japan
    Pain 138:525-36. 2008
    ..These results suggest that the glutamate-NO-cGMP-PKG pathway in the spinal cord may be involved in the mechanism of PAF-induced tactile allodynia, and GlyR alpha3 could be a target molecule through which PKG induces allodynia...
  6. ncbi request reprint Assessing an eating disorder induced by 6-OHDA and the possibility of nerve regeneration therapy by transplantation of neural progenitor cells in rats
    Tomoya Kitayama
    Department of Dental Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences 1 2 3 Kasumi, Mimami ku, Hiroshima, 734 8553 Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 27:109-16. 2007
    ..Transplantation of NPCs may cure 6-OHDA-induced eating disorders accompanied by the protection of neurons from the toxin...
  7. doi request reprint P2X(7) receptor stimulation in primary cultures of rat spinal microglia induces downregulation of the activity for glutamate transport
    Norimitsu Morioka
    Department of Dental Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan
    Glia 56:528-38. 2008
    ..These results suggest that the activation of P2X(7) receptors in spinal microglia is important in the regulation of glutamate transport via activation of the extracellular signal-regulated kinase cascade and production of oxidants...
  8. pmc Palliation of bone cancer pain by antagonists of platelet-activating factor receptors
    Katsuya Morita
    Department of Pharmacology, Faculty of Nursing, Hiroshima Bunka Gakuen University, Hiroshima, Japan Cancer Pathophysiology, Division National Cancer Center Research Institute, Tokyo, Japan Department of Cell and Molecular Pharmacology, Division of Basic Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan
    PLoS ONE 9:e91746. 2014
    ..The present results suggest that PAF receptor antagonists in combination with, or without, opioids may represent a new strategy for the treatment of persistent bone cancer pain and improve the quality of life of patients. ..
  9. ncbi request reprint Cyclic ADP-ribose mediates formyl methionyl leucyl phenylalanine (fMLP)-induced intracellular Ca(2+) rise and migration of human neutrophils
    Katsuya Morita
    Department of Dental Pharmacology, Hiroshima University Graduate School of Biomedical Sciences, Japan
    J Pharmacol Sci 106:492-504. 2008
    ..This process may be involved in fMLP-induced intracellular Ca(2+) signaling and migration in human neutrophils...
  10. ncbi request reprint Analgesic action of nicotine on tibial nerve transection (TNT)-induced mechanical allodynia through enhancement of the glycinergic inhibitory system in spinal cord
    Md Joynal Abdin
    Department of Dental Pharmacology, Division of Integrated Medical Science, Hiroshima University Graduate School of Biomedical Sciences, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    Life Sci 80:9-16. 2006
    ..Together, these results indicate that the alpha4beta2 and alpha7 nAChR system, by enhancing the activities of glycinergic neurons at the spinal level, exerts a suppressive effect on the nociceptive transduction in neuropathic pain...