A Kikuchi

Summary

Affiliation: Hiroshima University
Country: Japan

Publications

  1. ncbi Roles of Axin in the Wnt signalling pathway
    A Kikuchi
    Department of Biochemistry, Hiroshima University School of Medicine, Kasumi, Minami Ku, Japan
    Cell Signal 11:777-88. 1999
  2. ncbi Modulation of Wnt signaling by Axin and Axil
    A Kikuchi
    Department of Biochemistry, Hiroshima University School of Medicine, Japan
    Cytokine Growth Factor Rev 10:255-65. 1999
  3. pmc Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein
    S Hino
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3, Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Mol Cell Biol 21:330-42. 2001
  4. ncbi Epsin binds to the EH domain of POB1 and regulates receptor-mediated endocytosis
    K Morinaka
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Oncogene 18:5915-22. 1999
  5. pmc Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos
    H Yamamoto
    Department of Biochemistry, Hiroshima University School of Medicine, Japan
    Mol Cell Biol 18:2867-75. 1998
  6. pmc Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway
    M Furuhashi
    Department of Biochemistry, The Japanese Foundation for Cancer Research JFCR Cancer Institute, Toshima ku, Tokyo 170 8455, Japan
    Mol Cell Biol 21:5132-41. 2001
  7. ncbi Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon
    M Kishida
    Department of Biochemistry, Faculty of Medicine, Hiroshima University, Kasumi, Minami-ku, Hiroshima 734-8551, Japan
    J Biol Chem 276:33147-55. 2001
  8. ncbi Inhibition of Wnt signaling pathway by a novel axin-binding protein
    T Kadoya
    Department of Biochemistry and Second Department of Surgery, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, PRESTO, Japan
    J Biol Chem 275:37030-7. 2000
  9. ncbi Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylation
    K Kariya
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Biol Chem 275:18399-406. 2000
  10. ncbi A novel beta-catenin-binding protein inhibits beta-catenin-dependent Tcf activation and axis formation
    I Sakamoto
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, PRESTO, Japan
    J Biol Chem 275:32871-8. 2000

Collaborators

Detail Information

Publications53

  1. ncbi Roles of Axin in the Wnt signalling pathway
    A Kikuchi
    Department of Biochemistry, Hiroshima University School of Medicine, Kasumi, Minami Ku, Japan
    Cell Signal 11:777-88. 1999
    ..Thus, Axin acts as a scaffold protein in the Wnt signalling pathway, thereby regulating cellular functions...
  2. ncbi Modulation of Wnt signaling by Axin and Axil
    A Kikuchi
    Department of Biochemistry, Hiroshima University School of Medicine, Japan
    Cytokine Growth Factor Rev 10:255-65. 1999
    ..Axil has similar functions to Axin. Thus, Axin and Axil act as scaffold proteins in the Wnt signaling pathway, thereby modulating the Wnt-dependent cellular functions...
  3. pmc Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein
    S Hino
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3, Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Mol Cell Biol 21:330-42. 2001
    ..Therefore, these results suggest that Idax functions as a negative regulator of the Wnt signaling pathway by directly binding to the PDZ domain of Dvl...
  4. ncbi Epsin binds to the EH domain of POB1 and regulates receptor-mediated endocytosis
    K Morinaka
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Oncogene 18:5915-22. 1999
    ....
  5. pmc Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos
    H Yamamoto
    Department of Biochemistry, Hiroshima University School of Medicine, Japan
    Mol Cell Biol 18:2867-75. 1998
    ..These results indicate that Axil negatively regulates the Wnt signaling pathway by mediating GSK-3beta-dependent phosphorylation of beta-catenin, thereby inhibiting axis formation...
  6. pmc Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway
    M Furuhashi
    Department of Biochemistry, The Japanese Foundation for Cancer Research JFCR Cancer Institute, Toshima ku, Tokyo 170 8455, Japan
    Mol Cell Biol 21:5132-41. 2001
    ..Axin may thus function as an adapter of Smad3, facilitating its activation by TGF-beta receptors for efficient TGF-beta signaling...
  7. ncbi Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon
    M Kishida
    Department of Biochemistry, Faculty of Medicine, Hiroshima University, Kasumi, Minami-ku, Hiroshima 734-8551, Japan
    J Biol Chem 276:33147-55. 2001
    ..These results indicate that Dvl and CKIepsilon synergistically activated the Wnt signaling pathway and that the binding of the complex of Dvl and CKIepsilon to Axin is necessary for their synergistic action...
  8. ncbi Inhibition of Wnt signaling pathway by a novel axin-binding protein
    T Kadoya
    Department of Biochemistry and Second Department of Surgery, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, PRESTO, Japan
    J Biol Chem 275:37030-7. 2000
    ..These results suggest that Axam regulates the Wnt signaling pathway negatively by inhibiting the binding of Dvl to Axin...
  9. ncbi Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylation
    K Kariya
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Biol Chem 275:18399-406. 2000
    ..These results suggest that phosphorylation of Epsin in mitotic phase inhibits receptor-mediated endocytosis by disassembly of its complex with POB1 and alpha-adaptin...
  10. ncbi A novel beta-catenin-binding protein inhibits beta-catenin-dependent Tcf activation and axis formation
    I Sakamoto
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, PRESTO, Japan
    J Biol Chem 275:32871-8. 2000
    ..Thus, Duplin is a nuclear protein that inhibits beta-catenin signaling...
  11. ncbi Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A
    H Yamamoto
    Department of Biochemistry, Faculty of Medicine, Hiroshima University, 1 2 3, Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Biol Chem 276:26875-82. 2001
    ..Taken together with the previous observations that PR61 interacts with APC and functions upstream of beta-catenin, these results demonstrate that PR61 regulates the Wnt signaling pathway at various steps...
  12. ncbi GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin
    S Ikeda
    Department of Biochemistry, Hiroshima University School of Medicine, Japan
    Oncogene 19:537-45. 2000
    ..Taken together, these results suggest that GSK-3beta-dependent phosphorylation of APC can be modulated by beta-catenin and PP2A complexed with Axin...
  13. ncbi Ras-interacting domain of Ral GDP dissociation stimulator like (RGL) reverses v-Ras-induced transformation and Raf-1 activation in NIH3T3 cells
    M Okazaki
    Department of Biochemistry, Hiroshima University School of Medicine, Japan
    Cancer Res 56:2387-92. 1996
    ....
  14. pmc DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability
    S Kishida
    Department of Biochemistry, Hiroshima University School of Medicine, Minami Ku, Hiroshima 734 8551, Japan
    Mol Cell Biol 19:4414-22. 1999
    ..These results indicate that the DIX domains of Dvl-1 and Axin are important for protein-protein interactions and that they are necessary for the ability of Dvl-1 and Axin to regulate the stability of beta-catenin...
  15. pmc Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors
    S Nakashima
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    EMBO J 18:3629-42. 1999
    ....
  16. ncbi Axin directly interacts with plakoglobin and regulates its stability
    S Kodama
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3, Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    J Biol Chem 274:27682-8. 1999
    ..These results suggest that Axin regulates the stability of plakoglobin by enhancing its phosphorylation by GSK-3beta and that Axin may act on beta-catenin and plakoglobin in similar manners...
  17. pmc Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
    S Ikeda
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3, Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    EMBO J 17:1371-84. 1998
    ..These results suggest that rAxin negatively regulates the Wnt signaling pathway by interacting with GSK-3beta and beta-catenin and mediating the signal from GSK-3beta to beta-catenin...
  18. ncbi Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis
    T Itoh
    Department of Biochemistry, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
    Science 291:1047-51. 2001
    ..Thus, interaction between the ENTH domain and PtdIns(4,5)P2 is essential for endocytosis mediated by clathrin-coated pits...
  19. pmc Yeast glycogen synthase kinase 3 is involved in protein degradation in cooperation with Bul1, Bul2, and Rsp5
    T Andoh
    Department of Biochemistry, Hiroshima University School of Medicine, Minami Ku, Hiroshima, Japan
    Mol Cell Biol 20:6712-20. 2000
    ..Furthermore, Rog1 is stabilized in the npi1 mutant, in which RSP5 expression levels are reduced. These results suggest that yeast GSK-3 regulates the stability of Rog1 in cooperation with Bul1, Bul2, and Rsp5...
  20. ncbi Regulation of beta-catenin signaling in the Wnt pathway
    A Kikuchi
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3, Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    Biochem Biophys Res Commun 268:243-8. 2000
    ..The amounts and functions of beta-catenin are regulated in both the cytoplasm and nucleus. Its molecular mechanisms are becoming increasingly well understood...
  21. doi AIP regulates stability of Aurora-A at early mitotic phase coordinately with GSK-3beta
    K Fumoto
    Department of Biochemistry, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Oncogene 27:4478-87. 2008
    ..These results suggest that GSK-3beta modulates the early mitotic Aurora-A level through binding and phosphorylating AIP...
  22. pmc Tissue and subcellular distributions of the smg-21/rap1/Krev-1 proteins which are partly distinct from those of c-ras p21s
    S Kim
    Department of Biochemistry, Kobe University School of Medicine, Japan
    Mol Cell Biol 10:2645-52. 1990
    ....
  23. ncbi Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral
    M Ikeda
    Department of Biochemistry, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734, Japan
    J Biol Chem 273:814-21. 1998
    ..These results suggest that RalBP1 makes a complex with POB1 and that this complex may provide a link between tyrosine kinase, Src homology 3 (SH3)-containing protein, and Ral...
  24. doi Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase
    H Yamamoto
    Department of Biochemistry, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Oncogene 29:2036-46. 2010
    ..These results suggest that Wnt5a promotes the aggressiveness of prostate cancer and that its expression is involved in relapse after prostatectomy...
  25. ncbi Purification, characterization, and possible functions of small molecular weight GTP-binding proteins
    Y Takai
    Department of Biochemistry, Kobe University School of Medicine, Japan
    Am J Hypertens 3:220S-223S. 1990
    ..We conclude that small Mr G proteins and large Mr G proteins are components of large intracellular regulatory and messenger systems with specific roles in cell function regulation...
  26. ncbi Crystallization and preliminary X-ray diffraction analysis of a rat biliverdin reductase
    D Sun
    Department of Biochemistry, Yamagata University School of Medicine, Yamagata 990 9585, Japan
    Acta Crystallogr D Biol Crystallogr 56:1180-2. 2000
    ..89, b = 70.41, c = 87.76 A. The complete determination of the crystallographic structure is currently in progress using MAD (multiwavelength anomalous diffraction) data from an Ir-derivative crystal...
  27. ncbi Chondrocyte-derived ezrin-like domain containing protein (CDEP), a rho guanine nucleotide exchange factor, is inducible in chondrocytes by parathyroid hormone and cyclic AMP and has transforming activity in NIH3T3 cells
    Y Koyano
    Department of Biochemistry, Hiroshima University School of Dentistry, Japan
    Osteoarthritis Cartilage 9:S64-8. 2001
    ..CONCLUSIONS: CDEP is a novel GEF for Rho family GTPases with the transforming activity. CDEP may play a role in mediating or modulating the action of cAMP-elevating hormones on maturing chondrocytes...
  28. ncbi Characterization of the interaction of Raf-1 with ras p21 or 14-3-3 protein in intact cells
    S Koyama
    Department of Biochemistry, Hiroshima University School of Medicine, Japan
    FEBS Lett 368:321-5. 1995
    ..While Raf(1-135) did not interact with 14-3-3 protein, Raf(136-322) did. These results clearly indicate that Raf-1 simultaneously interacts with both ras p21 and 14-3-3 protein through the distinct binding domains in intact cells...
  29. ncbi Profiling of genes expressed in human monocytes and monocyte-derived dendritic cells using cDNA expression array
    N Lapteva
    Department of Human Genetics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Br J Haematol 114:191-7. 2001
    ..Moreover, our data show the presence of a 'switch-on' step for the TNF-alpha and TNFRII gene expression in immature DCs for further differentiation into mature DCs...
  30. ncbi NBP1 (Nap1 binding protein 1), an essential gene for G2/M transition of Saccharomyces cerevisiae, encodes a protein of distinct sub-nuclear localization
    Y Shimizu
    Division of Gene Regulatorics, Institute for Enzyme Research, The University of Tokushima, Tokushima, Japan
    Gene 246:395-404. 2000
    ..This mutant also confers resistance against benomyl, a microtubule-destabilizing agent. Judging from the green fluorescent protein (GFP) signal fused with Nbp1p, this protein localizes in the nucleus as one or two tiny dots...
  31. pmc beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
    W Chen
    Department of Medicine, Howard Hughes Medical Institute, Duke University Medical Center, Box 3821, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 98:14889-94. 2001
    ....
  32. ncbi Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation
    Y Kawamura
    Department of Dementia Research, National Insititute for Longevity Sciences, Obu, Aichi, Japan
    Eur J Biochem 268:3036-41. 2001
    ..Thus, it appears that PS1 (M146L) mutation down-regulates the Wnt-3A-induced accumulation of beta-catenin due to an increase in the level of phosphorylated beta-catenin...
  33. pmc An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin
    M Kitagawa
    Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    EMBO J 18:2401-10. 1999
    ..SCFFWD1 may be critical for tumor development and suppression through regulation of beta-catenin protein stability...
  34. ncbi Hydrological setting of infertile species-rich wetland--a case study in the warm temperate Japan
    A Kikuchi
    Graduate School for International Development and Cooperation, Hiroshima University, Higashi Hiroshima City, 739 8529 Japan
    J Environ Sci (China) 15:279-83. 2003
    ....
  35. ncbi Weekly carboplatin and paclitaxel is safe, active, and well tolerated in recurrent ovarian cancer cases of Japanese women previously treated with cisplatin-containing multidrug chemotherapy
    A Kikuchi
    Department of Obstetrics and Gynecology, Nihon University School of Medicine, 30 1 Oyaguchi, Kamimachi, Itabashi, Tokyo 173 8610, Japan
    Int J Gynecol Cancer 15:45-9. 2005
    ..As second-line treatment of ovarian cancer should primarily provide high TI, WTJ regimen appears a better candidate, but its long-term survival benefit should be tested against MTJ...
  36. pmc Association of susceptibility to the development of pneumonia in the older Japanese population with haem oxygenase-1 gene promoter polymorphism
    H Yasuda
    J Med Genet 43:e17. 2006
    ....
  37. ncbi Pns4 of rice dwarf virus is a phosphoprotein, is localized around the viroplasm matrix, and forms minitubules
    T Wei
    Laboratory of Virology, National Agricultural Research Center, Tsukuba, Ibaraki, Japan
    Arch Virol 151:1701-12. 2006
    ..Since viroplasms are believed to be the site of RDV replication, the intracellular location of Pns4 suggests that this protein might be involved in the process of assembly of the RDV virion...
  38. ncbi Molecular cloning of the human cDNA for a stimulatory GDP/GTP exchange protein for c-Ki-ras p21 and smg p21
    A Kikuchi
    Department of Biochemistry, Kobe University School of Medicine, Japan
    Oncogene 7:289-93. 1992
    ..The isolated cDNA is expressed in Escherichia coli, and the encoded protein shows the physical and functional properties similar to those of bovine smg GDS...
  39. ncbi Identification and molecular cloning of yeast homolog of nucleosome assembly protein I which facilitates nucleosome assembly in vitro
    Y Ishimi
    Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan
    J Biol Chem 266:7025-9. 1991
    ..Proteins recognized by the anti-NAP-I antibody were also present in Xenopus oocytes and Drosophila cultured cells. Possible roles of NAP-I are discussed in relation to other nucleosome assembly proteins...
  40. ncbi Functional analysis of nucleosome assembly protein, NAP-1. The negatively charged COOH-terminal region is not necessary for the intrinsic assembly activity
    T Fujii-Nakata
    Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan
    J Biol Chem 267:20980-6. 1992
    ..This minimal size fragment could form the 12 S NAP-1-histone complex as the whole protein could, whereas deleted fragments on either side could bind with core histones only to form aggregates...
  41. ncbi Inhibition of the ras p21 GTPase-activating protein-stimulated GTPase activity of c-Ha-ras p21 by smg p21 having the same putative effector domain as ras p21s
    Y Hata
    Department of Biochemistry, Kobe University School of Medicine, Japan
    J Biol Chem 265:7104-7. 1990
    ..c-Ha-ras p21 did not inhibit the smg p21 GAP1- or -2-stimulated GTPase activity of smg p21. These results indicate that ras p21 GAP interacts with smg p21 without the subsequent stimulation of its GTPase activity...
  42. ncbi Molecular cloning of smg p21B and identification of smg p21 purified from bovine brain and human platelets as smg p21B
    Y Matsui
    Research Center, Mitsubishi Kasei Corporation, Yokohama, Japan
    Biochem Biophys Res Commun 166:1010-6. 1990
    ..Amino acid sequence analysis indicates that smg p21A is identical with the rap1A and Krev-1 proteins and smg p21B is identical with the rap1B protein...
  43. pmc The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway
    K Sawamoto
    Division of Neuroanatomy, Department of Neuroscience, Biomedical Research Center, Osaka University Graduate School of Medicine, Osaka 565 0871, Japan
    J Cell Biol 146:361-72. 1999
    ..These results indicate that DRal regulates developmental cell shape changes through the JNK pathway...
  44. ncbi Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1)
    S Koshiba
    Cellular Signaling Laboratory, The Institute of Physical and Chemical Research RIKEN, Wako, Saitama, Japan
    FEBS Lett 442:138-42. 1999
    ....
  45. pmc Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities
    K N Meyer
    Medizinische Poliklinik, University of Wurzburg, Germany
    J Cell Biol 136:775-88. 1997
    ..Scaffold-associated topoisomerase IIalpha appears not to be involved in catalytic DNA turnover, though it may play a role in the replicational cycle of centriols, where it accumulates during M phase...
  46. ncbi Clinical significance of TAL1 gene alteration in childhood T-cell acute lymphoblastic leukemia and lymphoma
    A Kikuchi
    Division of Hematology Oncology, Saitama Children s Medical Center, Japan
    Leukemia 7:933-8. 1993
    ..We conclude that tald rearrangement is restricted to T-cell ALL, for which it provides a useful clonal marker. Such patients with this rearrangement may constitute a subgroup of T-cell ALL with a good prognosis...
  47. pmc ralGDS family members interact with the effector loop of ras p21
    A Kikuchi
    Cardiovascular Research Institute, University of California San Francisco 94143 0130
    Mol Cell Biol 14:7483-91. 1994
    ..Therefore, ralGDS family members may be effector proteins of ras p21 or may inhibit interactions between ras p21 and its effectors...
  48. ncbi A new yeast gene, HTR1, required for growth at high temperature, is needed for recovery from mating pheromone-induced G1 arrest
    Y Kikuchi
    Department of Plant Sciences, Graduate School of Science, University of Tokyo, Japan
    Mol Gen Genet 245:107-16. 1994
    ..Thus the gene has at least two functions and is designated HTR1 (required for high temperature growth and recovery from G1 arrest induced by mating pheromone)...
  49. ncbi Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development
    K Sawamoto
    Department of Neuroanatomy, Biomedical Research Center, Osaka University Medical School, Suita, Japan
    Oncogene 18:1967-74. 1999
    ..In addition, the phenotype was synergistically enhanced by the coexpression of RhoA. These results suggest that Ral functions to control the cytoskeletal structure required for cell shape changes during Drosophila development...
  50. pmc Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis
    K Nagata
    Department of Biomolecular Engineering, Faculty of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan
    Proc Natl Acad Sci U S A 92:4279-83. 1995
    ..Studies with mutant TAF-I proteins devoid of this acidic region indicated that the acidic region is essential for TAF-I activity...
  51. pmc Members of the NAP/SET family of proteins interact specifically with B-type cyclins
    D R Kellogg
    Department of Physiology, University of California, San Francisco 94143 0444, USA
    J Cell Biol 130:661-73. 1995
    ..This protein is the Xenopus homolog of the human SET protein, which was previously identified as part of a putative oncogenic fusion protein (Von Lindern et al., 1992)...
  52. ncbi [Clinical courses and pathological findings in two gay male patients with acquired immunodeficiency syndrome infected in Japan]
    S Takamizawa
    Second Department of Internal Medicine, Jikei University School of Medicine, Tokyo Japan
    Kansenshogaku Zasshi 64:210-7. 1990
    ..Furthermore, it is suggested that homosexual patients with AIDS may have unique opportunistic infections such as amebic dysentery or Giardia lamblia unlike other AIDS patients related to hemophilia...
  53. ncbi ZIP kinase identified as a novel myosin regulatory light chain kinase in HeLa cells
    M Murata-Hori
    Department of Biological Science, Faculty of Science, Hiroshima University, Higashi Hiroshima, Japan
    FEBS Lett 451:81-4. 1999
    ..Phosphorylation of myosin II by HeLa ZIPK resulted in activation of actin-activated MgATPase activity of myosin II. HeLa ZIPK is the first non-muscle MLCK that phosphorylates MRLC at two sites...