Satoshi Ikeda

Summary

Affiliation: Hiroshima University
Country: Japan

Publications

  1. ncbi Immunohistochemistry of cyclin D1 and beta-catenin, and mutational analysis of exon 3 of beta-catenin gene in parathyroid adenomas
    Satoshi Ikeda
    Second Department of Surgery, Hiroshima University Faculty of Medicine, Hiroshima 734 8551, Japan
    Int J Oncol 20:463-6. 2002
  2. pmc Combined immunohistochemistry of beta-catenin, cytokeratin 7, and cytokeratin 20 is useful in discriminating primary lung adenocarcinomas from metastatic colorectal cancer
    Satoshi Ikeda
    Department of Endoscopic Surgery and Surgical Science, Graduate School of Biomedical Science, Hiroshima University, 1 2 3 Kasumi, Hiroshima, Japan
    BMC Cancer 6:31. 2006
  3. ncbi Immunohistochemical and mutational analyses of beta-catenin, Ki-ras, and p53 in two subtypes of colorectal mucinous carcinoma
    Satoshi Ikeda
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Clin Cancer Res 9:5660-5. 2003
  4. pmc Abscess in the inguinal hernial sac after peritonitis surgery: a case report
    Satoshi Ikeda
    Department of Endoscopic Surgery and Surgical Science, Graduate School of Biomedical Science, Hiroshima University, Hiroshima, Japan
    World J Gastroenterol 15:1007-9. 2009
  5. doi Adequate lymph node examination is essential to ensure the prognostic value of the lymph node ratio in patients with stage III colorectal cancer
    Manabu Shimomura
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    Surg Today 41:1370-9. 2011
  6. ncbi Alterations and correlations of the components in the Wnt signaling pathway and its target genes in breast cancer
    Shinji Ozaki
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Oncol Rep 14:1437-43. 2005
  7. ncbi Immunohistochemical and sequencing analyses of the Wnt signaling components in Japanese anaplastic thyroid cancers
    Takeshi Kurihara
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Thyroid 14:1020-9. 2004
  8. ncbi Immunohistochemical and mutational analyses of Wnt signaling components and target genes in intrahepatic cholangiocarcinomas
    Noriaki Tokumoto
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Int J Oncol 27:973-80. 2005
  9. ncbi Immunohistochemical analysis and mutational analyses of beta-catenin, Axin family and APC genes in hepatocellular carcinomas
    Yasuyo Ishizaki
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8551, Japan
    Int J Oncol 24:1077-83. 2004
  10. pmc Retroperitoneal abscess complicated with necrotizing fasciitis of the thigh in a patient with sigmoid colon cancer
    Yuji Takakura
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Science, Hiroshima University, Minami Ku, Hiroshima, Japan
    World J Surg Oncol 7:74. 2009

Collaborators

Detail Information

Publications32

  1. ncbi Immunohistochemistry of cyclin D1 and beta-catenin, and mutational analysis of exon 3 of beta-catenin gene in parathyroid adenomas
    Satoshi Ikeda
    Second Department of Surgery, Hiroshima University Faculty of Medicine, Hiroshima 734 8551, Japan
    Int J Oncol 20:463-6. 2002
    ..These results indicate that cyclin D1 is frequently accumulated in parathyroid adenomas, independently of dysfunction in the Wnt signaling pathway...
  2. pmc Combined immunohistochemistry of beta-catenin, cytokeratin 7, and cytokeratin 20 is useful in discriminating primary lung adenocarcinomas from metastatic colorectal cancer
    Satoshi Ikeda
    Department of Endoscopic Surgery and Surgical Science, Graduate School of Biomedical Science, Hiroshima University, 1 2 3 Kasumi, Hiroshima, Japan
    BMC Cancer 6:31. 2006
    ..The purpose of this study was to evaluate the clinical usefulness of immunohistochemistry of beta-catenin, cytokeratin (CK) 7, and CK20 for the discriminating diagnosis of lung cancer...
  3. ncbi Immunohistochemical and mutational analyses of beta-catenin, Ki-ras, and p53 in two subtypes of colorectal mucinous carcinoma
    Satoshi Ikeda
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Clin Cancer Res 9:5660-5. 2003
    ....
  4. pmc Abscess in the inguinal hernial sac after peritonitis surgery: a case report
    Satoshi Ikeda
    Department of Endoscopic Surgery and Surgical Science, Graduate School of Biomedical Science, Hiroshima University, Hiroshima, Japan
    World J Gastroenterol 15:1007-9. 2009
    ..Five days after the second operation, computed tomography revealed an abscess in the left inguinal hernial sac. Subsequently, hernioplasty and resection of the inflamed sac were performed...
  5. doi Adequate lymph node examination is essential to ensure the prognostic value of the lymph node ratio in patients with stage III colorectal cancer
    Manabu Shimomura
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
    Surg Today 41:1370-9. 2011
    ....
  6. ncbi Alterations and correlations of the components in the Wnt signaling pathway and its target genes in breast cancer
    Shinji Ozaki
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Oncol Rep 14:1437-43. 2005
    ....
  7. ncbi Immunohistochemical and sequencing analyses of the Wnt signaling components in Japanese anaplastic thyroid cancers
    Takeshi Kurihara
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Thyroid 14:1020-9. 2004
    ..Furthermore, cyclin D1 and c-myc frequently accumulated in ATC, independently of dysfunction in the Wnt signaling pathway...
  8. ncbi Immunohistochemical and mutational analyses of Wnt signaling components and target genes in intrahepatic cholangiocarcinomas
    Noriaki Tokumoto
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Int J Oncol 27:973-80. 2005
    ..Based on these results, we speculated that the Wnt signaling pathway plays an important role in carcinogenesis in ICC through overexpression of its target genes, particularly cyclin D1...
  9. ncbi Immunohistochemical analysis and mutational analyses of beta-catenin, Axin family and APC genes in hepatocellular carcinomas
    Yasuyo Ishizaki
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8551, Japan
    Int J Oncol 24:1077-83. 2004
    ..In conclusion, in addition to mutations in the beta-catenin gene, mutations in the Axin1 and Axin2 genes may alter the Wnt signaling pathway, resulting in accumulation of beta-catenin...
  10. pmc Retroperitoneal abscess complicated with necrotizing fasciitis of the thigh in a patient with sigmoid colon cancer
    Yuji Takakura
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Science, Hiroshima University, Minami Ku, Hiroshima, Japan
    World J Surg Oncol 7:74. 2009
    ..Necrotizing fasciitis of the thigh due to the colon cancer, especially during chemotherepy, has not been previously reported...
  11. doi Gastrointestinal stromal tumors of the small intestine in pediatric populations: a case report and literature review
    Manabu Shimomura
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 7348551, Japan
    Pediatr Surg Int 26:649-54. 2010
    ..In pediatric populations, GISTs of the small intestine were expected to show a better response to imatinib treatment than gastric GISTs because of the alterations in the c-kit gene...
  12. doi Alterations in portal vein blood pH, hepatic functions, and hepatic histology in a porcine carbon dioxide pneumoperitoneum model
    Makoto Yoshida
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Surg Endosc 24:1693-700. 2010
    ..In this study, changes in liver functions and liver histology were investigated during CO(2) pneumoperitoneum in a large animal model...
  13. doi Preservation of peritoneal fibrinolysis owing to decreased transcription of plasminogen activator inhibitor-1 in peritoneal mesothelial cells suppresses postoperative adhesion formation in laparoscopic surgery
    Manabu Shimomura
    Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan
    Surgery 153:344-56. 2013
    ..This study compared peritoneal fibrinolysis and adhesion formation after laparoscopic surgery (LAP) and open surgery (OP)...
  14. ncbi Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability
    Yosuke Shimizu
    Second Department of Surgery, Hiroshima University Faculty of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima, Japan
    Genes Chromosomes Cancer 33:73-81. 2002
    ..Thus, alteration in the Wnt signaling pathway is frequently observed in CRC with MSI, including hereditary nonpolyposis colorectal cancer, as well as in familial adenomatous polyposis and sporadic CRC without MSI...
  15. doi Hybrid hand-assisted colectomy for transverse colon cancer: a useful technique for non-expert laparoscopic surgeons
    Yuji Takakura
    Department of Endoscopic Surgery and Surgical Science, Graduate School of Biomedical Science, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    World J Surg 33:2683-7. 2009
    ..This procedure combines the established convenient and safe techniques of open surgery with the less invasive hand-assisted laparoscopic approach...
  16. ncbi Allochronic overlapping malignancies after renal transplantation in a patient with p53 gene mutation: report of a case
    Teruhiko Kitayama
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Surg Today 34:473-6. 2004
    ..We suggest that the effects of the immunosuppressive drugs combined with the p53 gene abnormality accelerated tumor development in this patient...
  17. ncbi Expression and localization of MUC1, MUC2, MUC5AC and small intestinal mucin antigen in pancreatic tumors
    Hiroyuki Yamasaki
    Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Minami Ku, Hiroshima 734 8551, Japan
    Int J Oncol 24:107-13. 2004
    ..04). In conclusion, the localization of mucin expression, especially stromal expression of MUC1 or SIMA, might be a prognostic factor for patients with pancreatic cancer...
  18. doi Objective assessment of endoscopic surgical skills by analyzing direction-dependent dexterity using the Hiroshima University Endoscopic Surgical Assessment Device (HUESAD)
    Hiroyuki Egi
    Department of Endoscopic Surgery and Surgical Science, Graduate School of Hiroshima University, and Department of Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan
    Surg Today 38:705-10. 2008
    ..We evaluated our system of objectively assessing endoscopic surgical skills...
  19. ncbi [Current practices of perioperative nutritional therapy in colorectal surgery]
    Hiroki Ohge
    Department of Surgery, Hiroshima University, Hiroshima, Japan
    Nihon Geka Gakkai Zasshi 111:18-22. 2010
    ..Early restoration of gastrointestinal function can reduce postoperative complications and the length of hospital stays...
  20. ncbi Correlation between EGFR gene mutation pattern and Akt phosphorylation in pulmonary adenocarcinomas
    Satoshi Ikeda
    Department of Pathology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan
    Pathol Int 57:268-75. 2007
    ..0014). In addition, there was a significant correlation between the L858R mutation and the expression of p-Akt (P=0.040). It is suggested that the activation of Akt is dependent on EGFR mutation pattern...
  21. ncbi Detection of gene point mutation in paraffin sections using in situ loop-mediated isothermal amplification
    Satoshi Ikeda
    Department of Pathology, Tsuchiura Kyodo General Hospital, Ibaraki, Japan
    Pathol Int 57:594-9. 2007
    ..It is concluded that the present method is useful for pathological and genetic diagnoses...
  22. ncbi Clinicopathologic roles of tumor-infiltrating lymphocytes and CD8-positive lymphocytes in lung cancer imprint smears in squamous cell carcinoma and adenocarcinoma
    Satoshi Ikeda
    Department of Pathology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan
    Acta Cytol 50:423-9. 2006
    ..To investigate the presence of tumor-infiltrating lymphocytes (TILs) and CD8-positive lymphocytes (CD8s) in lung cancers and to examine the prognostic significance of their relationship with clinicopathologic parameters...
  23. ncbi [Frequency of apoptotic cells and BAX positive cells in the lymph nodes of colorectal cancer patients with metastasis and micrometastasis]
    Satoshi Ikeda
    Department of Pathology, Tsuchiura Kyodo General Hospital, Tsuchiura 300 0053
    Rinsho Byori 51:409-13. 2003
    ..And it was suggested that those changes were correlated with inflow of isolated cancer cells and formation of metastatic foci in the lymph nodes, and may reflected the difference of immunological activity against cancer cells...
  24. ncbi Repetitive stretch induces c-fos and myogenin mRNA within several hours in skeletal muscle removed from rats
    Satoshi Ikeda
    Department of Rehabilitation and Physical Medicine, Faculty of Medicine, Kagoshima University, Kagoshima, Japan
    Arch Phys Med Rehabil 84:419-23. 2003
    ..To investigate what effect repetitive stretch has on gene transcription in muscle tissues removed from rats...
  25. ncbi Nepsilon-(Carboxymethyl)lysine induces gamma-glutamylcysteine synthetase in RAW264.7 cells
    Yoshiyuki Miyahara
    The Second Department of Internal Medicine, Nagasaki University School of Medicine, 852 8521, Nagasaki, Japan
    Biochem Biophys Res Commun 296:32-40. 2002
    ..Our results suggest that induction of gamma-GCS by CML adducts seems to increase the defense potential of cells against oxidative stress produced during glycation processes...
  26. ncbi Prognostic significance of gastric cancer metastasis in second-tier lymph nodes detected on reverse transcriptase-polymerase chain reaction and immunohistochemistry
    Satoshi Ikeda
    Department of Pathology, Tsuxhiura Kyodo General Hospital, Ibaraki, Japan
    Pathol Int 58:45-50. 2008
    ..154, 0.013, and 0.006, respectively. In conclusion, RT-PCR and CK staining for detection of metastasis in second-tier lymph nodes were more reliable prognostic indicators than conventional HE staining...
  27. ncbi High Pin1 expression is associated with tumor progression in colorectal cancer
    Junichi Kuramochi
    Department of Surgical Oncology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Surg Oncol 94:155-60. 2006
    ..Pin1 is over-expressed in some cancers such as prostate and breast cancers. This study aimed to determine whether Pin1 plays a role in colorectal tumorigenesis through the upregulation of beta-catenin and cyclin D1...
  28. ncbi A case of asymptomatic fusiform aneurysm of the superior vena cava detected by magnetic resonance imaging
    Seiji Koga
    Int J Cardiol 113:e39-41. 2006
    ..Based on previous reports, conservative management was planned with anticoagulation therapy as prophylaxis against thrombotic complications rather than surgical resection for aneurysm...
  29. ncbi Antiapoptotic activity of Akt is down-regulated by Ca2+ in myocardiac H9c2 cells. Evidence of Ca(2+)-dependent regulation of protein phosphatase 2Ac
    Chie Yasuoka
    Department of Biochemistry and Molecular Biology in Disease, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Medicine, Japan
    J Biol Chem 279:51182-92. 2004
    ..A long term change of [Ca2+]i regulates PP2Acalpha gene transcription via CRE, resulting in a change in the activation status of Akt leading to an altered susceptibility to apoptosis...
  30. ncbi The usefulness of immunostaining in washed cell cytological smears for differential diagnosis of B cell type malignant lymphoma
    Satoshi Ikeda
    Department of Pathology, Tsuchiura Kyodo General Hospital, Tsuchiura 300 0053
    Rinsho Byori 53:999-1004. 2005
    ..In addition, the rapid staining protocol in the present study was able to provide the results within 15 min. Therefore, it might be the most suitable method for the detection of immunoglobulin monoclonality in general laboratories...
  31. ncbi Chest pain and ST segment depression caused by expansion of gastric tube used for esophageal reconstruction
    Koichiro Sonoda
    Department of Internal Medicine, Nagasaki Memorial Hospital, 1 11 54 Fukahori machi, Nagasaki 851 0301
    Intern Med 44:217-21. 2005
    ..Angina-like chest pain associated with ST segment changes were caused by expansion of the gastric tube and compression of the heart...
  32. ncbi Immunohistochemical detection of telomerase reverse transcriptase (TERT) protein in benign and malignant tumor cells of the breast
    Satoshi Ikeda
    Department of Pathology, Tsuchiura Kyodo General Hospital, Tsuchiura 300 0053
    Rinsho Byori 53:487-93. 2005
    ..In malignant cases, it could be a useful indicator for the assessment of potential of lymph node metastasis [corrected]...