Research Topics
Species | Seiji HamaSummaryAffiliation: Hiroshima University Country: Japan Publications
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Detail Information
Publications
Post-stroke depression and apathy: Interactions between functional recovery, lesion location, and emotional responseSeiji Hama
Department of Neurosurgery, Graduate School of Biomedical Science, Hiroshima, University, Japan
Psychogeriatrics 11:68-76. 2011..Effective treatment of PSD/apathy requires a multidisciplinary approach, such that neuroanatomical/neurobiological, emotional, and physical (rehabilitation) domains are all addressed...- 'Insistence on recovery' as a positive prognostic factor in Japanese stroke patientsSeiji Hama
Department of Rehabilitation, Nishi Hiroshima Rehabilitation Hospital, Hiroshima, Japan
Psychiatry Clin Neurosci 62:386-95. 2008..The present study used two-step analyses to examine the effect of acceptance of disability or 'insistence on recovery' in Japanese stroke patients: first on their functional improvement and second, on their psychological symptoms... 
Sitting balance as an early predictor of functional improvement in association with depressive symptoms in stroke patientsSeiji Hama
Department of Rehabilitation, Nishi Hiroshima Rehabilitation Hospital, Hiroshima, Japan
Psychiatry Clin Neurosci 61:543-51. 2007..A rapid and simple screening method, 10-min sitting balance was related to scores for two core depressive symptoms, lowered mood and apathy, and was predictive of post-stroke ADL outcomes in the rehabilitation unit along with age...- Survivin subcellular localization in high-grade astrocytomas: simultaneous expression in both nucleus and cytoplasm is negative prognostic markerTaiichi Saito
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, 734 8551, Japan
J Neurooncol 82:193-8. 2007..The aim of the present study was to examine the relationship between prognosis and subcellular localization of survivin in high-grade astrocytoma... - The combination of low cytoplasmic and high nuclear expression of p27 predicts a better prognosis in high-grade astrocytomaToshikazu Hidaka
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, Japan
Anticancer Res 29:597-603. 2009..No previous reports have examined the subcellular localization of p27 in glioma which was evaluated here regarding the prognosis in high-grade astrocytomas... - Depression or apathy and functional recovery after strokeSeiji Hama
Department of Rehabilitation, Nishi Hiroshima Rehabilitation Hospital, Hiroshima, Japan
Int J Geriatr Psychiatry 22:1046-51. 2007..This study was designed to examine the effect of depression or apathy on functional recovery after stroke in 237 Japanese stroke patients... - Growth hormone receptor expression in brain tumorsTetsuhiko Sakoguchi
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
Hiroshima J Med Sci 61:1-6. 2012..However, among the non-GH-producing adenomas, GHR-positive tumors were significantly smaller. Thus, immunohistochemical GHR expression may have, at least in part, a negative impact on tumor growth potential in brain tumors... - Retinoblastoma protein prevents staurosporine-induced cell death in a retinoblastoma-defective human glioma cell lineFumiyuki Yamasaki
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
Pathobiology 74:22-31. 2007..To investigate the mechanism of staurosporine-induced glioma cell death and cell cycle arrest using adenovirus-mediated gene transfection, as well as the function of retinoblastoma (Rb) and genetic instability induced by staurosporine... - Masked hyperprolactinemia: tumor-derived factors inhibiting prolactin secretion caused by pituitary-stalk damageYasuyuki Kinoshita
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
J Clin Neurosci 18:1651-5. 2011..However, LIF expression was negatively correlated with the incidence of secondary hyperprolactinemia (p<0.01). Although secondary hyperprolactinemia might be caused by pituitary stalk damage, it is possible that LIF masks the effect... - Geminin: a good prognostic factor in high-grade astrocytic brain tumorsPrabin Shrestha
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
Cancer 109:949-56. 2007.... - Cytoplasmic, but not nuclear, p16 expression may signal poor prognosis in high-grade astrocytomasMuhamad Thohar Arifin
Department of Neurosurgery, Research Institute for Radiation Biology and Medicine, Graduate School of Medical Sciences, Hiroshima University, Hiroshima shi, Japan
J Neurooncol 77:273-7. 2006..The negative consequences of the cytoplasmic localization of p16 in patients with high-grade astrocytomas, on their prognosis, was investigated... - Prognosis of cerebellar glioblastomas: correlation between prognosis and immunoreactivity for epidermal growth factor receptor compared with supratentorial glioblastomasTaiichi Saito
Department of Neurosurgery, Hiroshima University, School of Medicine, Hiroshima, 734 8551, Japan
Anticancer Res 26:1351-7. 2006..Cerebellar glioblastomas (GBM) are rare tumors whose clinicopathological characteristics are not well understood... - Post-stroke affective or apathetic depression and lesion location: left frontal lobe and bilateral basal gangliaSeiji Hama
Department of Rehabilitation, Nishi Hiroshima Rehabilitation Hospital, Hiroshima, Japan
Eur Arch Psychiatry Clin Neurosci 257:149-52. 2007..The anatomical correlates of PSD differ depending on the PSD dimension (affective or apathetic) and may explain interstudy differences regarding the association between lesion location and type of PSD... - Supra-diaphragmatic pituitary adenoma removed through the trans-tuberculum sellae approach. Case reportYasuyuki Kinoshita
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, Minami Ku, Hiroshima, Japan
Neurol Med Chir (Tokyo) 52:91-5. 2012..The trans-tuberculum sellae approach is a less invasive method to remove pituitary adenoma located in the suprasellar region... - Expression of survivin in astrocytic tumors: correlation with malignant grade and prognosisYoshinori Kajiwara
Department of Neurosurgery, Faculty of Medicine, Hiroshima University, Hiroshima, Japan
Cancer 97:1077-83. 2003..Recently, survivin has been identified as a member of the inhibitor-of-apoptosis family. Survivin expression is considered an important prognostic factor of many tumors... - Post-operative hyponatremia in patients with pituitary adenoma: post-operative management with a uniform treatment protocolYasuyuki Kinoshita
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8551, Japan
Endocr J 58:373-9. 2011..Special attention and recovery effort should be given to elder patients with marked serum Na level decline after surgery... - Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell lineFumiyuki Yamasaki
Department of Neurosurgery, Faculty of Medicine, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima, Japan
Cancer Chemother Pharmacol 51:271-83. 2003..The mechanisms involved in the cell cycle and cell death remain unresolved despite much investigation. Staurosporine induces cell death and G1 or G2/M arrest in a dose-dependent manner, but the mechanisms remain unknown... - Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndromeShinya Matsuura
Department of Radiation Biology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan
Am J Med Genet A 140:358-67. 2006..These findings indicate the involvement of BubR1 in p55cdc-mediated mitotic checkpoint signaling, and suggest that >50% decrease in expression (or activity) of BubR1 is involved in the PCS syndrome... - Changes in the epithelium of Rathke cleft cyst associated with inflammationSeiji Hama
Department of Neurosurgery, Hiroshima University School of Medicine, Japan
J Neurosurg 96:209-16. 2002..Rathke cleft cysts (RCCs) are composed of tall, well-differentiated, ciliated columnar epithelia. Their structures are altered by hyperplasia or squamous metaplasia, but their cause remains unknown... - Malnutrition and nonthyroidal illness syndrome after strokeSeiji Hama
Division of Rehabilitation, Nishi Hiroshima Rehabilitation Hospital, Hiroshima 731 5143, Japan
Metabolism 54:699-704. 2005..Therefore, during the recovery period after stroke, it is important to determine whether NTIS is present and ensure proper intensive rehabilitation and nutritional management... - Vulnerable carotid arterial plaque causing repeated ischemic stroke can be detected with B-mode ultrasonography as a mobile component: Jellyfish signShinji Kume
Department of Radiology, Hibino Hospital, Asaminami ku, Hiroshima, Japan
Neurosurg Rev 33:419-30. 2010.... - Detection and differentiation of lactate and lipids by single-voxel proton MR spectroscopyFumiyuki Yamasaki
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Hiroshima, 734-8551, Japan
Neurosurg Rev 28:267-77. 2005..With our method of varying the TE, it is possible accurately and efficiently to detect lactate and lipids in the brain. We found a significant correlation between lactate and lipid expression and WHO grade of neuro-epithelial tumors... - Relationship between intratumoral hemorrhage and overexpression of vascular endothelial growth factor (VEGF) in pituitary adenomaKazunori Arita
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3, Kasumi, Minami Ku, Hiroshima 734 8551, Japan
Hiroshima J Med Sci 53:23-7. 2004..In conclusion, a positive relationship between VEGF expression and hemorrhage in pituitary adenoma was observed. The patho-mechanical significance of this correlation is under investigation... - Preparation of purified, sterilized, and stable adenovirus vectors using albuminMami Hosokawa
Department of Medical Oncology and Clinical Research, National Shikoku Cancer Center, 13-Horinocuhi, Matsuyama, Ehime, Japan
J Virol Methods 103:191-9. 2002..Furthermore, viral activity was retained within the 1% albumin solution for at least 1 week at 37 degrees C and for 2 weeks at 4 degrees C, whereas viral activity within the albumin-free solution was quickly lost... - Apparent diffusion coefficient of human brain tumors at MR imagingFumiyuki Yamasaki
Dept of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima Univ, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan
Radiology 235:985-91. 2005..CONCLUSION: ADC is useful for differentiation of some human brain tumors, particularly DNT, malignant lymphomas versus glioblastomas and metastatic tumors, and ependymomas versus PNETs...