Kenichi Hakamada

Summary

Affiliation: Hirosaki University School of Medicine
Country: Japan

Publications

  1. pmc Des-gamma-carboxy prothrombin as an important prognostic indicator in patients with small hepatocellular carcinoma
    Kenichi Hakamada
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:1370-7. 2008
  2. pmc An easier method for performing a pancreaticojejunostomy for the soft pancreas using a fast-absorbable suture
    Kenichi Hakamada
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:1091-6. 2008
  3. pmc Anaplastic carcinoma associated with a mucinous cystic neoplasm of the pancreas during pregnancy: report of a case and a review of the literature
    Kenichi Hakamada
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:132-5. 2008
  4. pmc Intraoperative ultrasound as an educational guide for laparoscopic biliary surgery
    Kenichi Hakamada
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:2370-6. 2008
  5. ncbi request reprint Warm ischemia and reperfusion injury in diet-induced canine fatty livers
    K Takahashi
    Second Department of Surgery, Hirosaki University School of Medicine, Japan
    Transplantation 69:2028-34. 2000
  6. ncbi request reprint Attenuation of graft injury in porcine liver transplantation from non-heart beating donor by FR167653
    Hiroaki Ono
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki Aomori, Japan
    Hepatogastroenterology 52:885-92. 2005
  7. doi request reprint Plasma exchange-based plasma recycling dialysis system as an artificial liver support
    Kentaro Takahashi
    Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Ther Apher Dial 12:264-70. 2008
  8. ncbi request reprint [Complete response obtained by preoperative chemotherapy in a case of T4 rectal cancer]
    Hiroshi Yokoyama
    Dept of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Japan
    Gan To Kagaku Ryoho 39:1954-6. 2012
  9. doi request reprint Gene expression of ATP-binding cassette transporters during liver regeneration after 90% hepatectomy in rats
    Norihisa Kimura
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036 8562, Aomori Province, Japan
    Int J Mol Med 30:28-34. 2012
  10. pmc Resection of a locally advanced hilar tumor and the hepatic artery after stepwise hepatic arterial embolization: a case report
    Takuya Miura
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:3587-90. 2008

Collaborators

Detail Information

Publications54

  1. pmc Des-gamma-carboxy prothrombin as an important prognostic indicator in patients with small hepatocellular carcinoma
    Kenichi Hakamada
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:1370-7. 2008
    ..To clarify the effect of a high des-gamma-carboxy prothrombin (DCP) level on the invasiveness and prognosis of small hepatocellular carcinoma...
  2. pmc An easier method for performing a pancreaticojejunostomy for the soft pancreas using a fast-absorbable suture
    Kenichi Hakamada
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:1091-6. 2008
    ..To clarify the usefulness of a new method for performing a pancreaticojejunostomy by using a fast-absorbable suture material irradiated polyglactin 910, and a temporary stent tube for a narrow pancreatic duct with a soft pancreatic texture...
  3. pmc Anaplastic carcinoma associated with a mucinous cystic neoplasm of the pancreas during pregnancy: report of a case and a review of the literature
    Kenichi Hakamada
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:132-5. 2008
    ..Although the origin of anaplastic carcinoma has not been determined yet, it should be remembered that anaplastic carcinoma can occur in association with mucinous cystic neoplasm of more benign histology...
  4. pmc Intraoperative ultrasound as an educational guide for laparoscopic biliary surgery
    Kenichi Hakamada
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:2370-6. 2008
    ....
  5. ncbi request reprint Warm ischemia and reperfusion injury in diet-induced canine fatty livers
    K Takahashi
    Second Department of Surgery, Hirosaki University School of Medicine, Japan
    Transplantation 69:2028-34. 2000
    ..Because extensive investigation of mechanisms underlying such nonfunction has been limited largely to rodents, we made a new fatty liver model in dogs and studied primary nonfunction after warm ischemia...
  6. ncbi request reprint Attenuation of graft injury in porcine liver transplantation from non-heart beating donor by FR167653
    Hiroaki Ono
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki Aomori, Japan
    Hepatogastroenterology 52:885-92. 2005
    ..This study was carried out to investigate whether a newly synthesized cytokine suppressive anti-inflammatory agent, FR167653, attenuates graft injury in OLTx from NHBD...
  7. doi request reprint Plasma exchange-based plasma recycling dialysis system as an artificial liver support
    Kentaro Takahashi
    Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Ther Apher Dial 12:264-70. 2008
    ..Safety of this PE-based PRD system was demonstrated and the removal of toxic substances was significant. This study confirmed the clinical utility of this system as an artificial liver support...
  8. ncbi request reprint [Complete response obtained by preoperative chemotherapy in a case of T4 rectal cancer]
    Hiroshi Yokoyama
    Dept of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Japan
    Gan To Kagaku Ryoho 39:1954-6. 2012
    ..Downstaging chemotherapy is expected to enhance the role of function-preserving surgery for T4 rectal cancer...
  9. doi request reprint Gene expression of ATP-binding cassette transporters during liver regeneration after 90% hepatectomy in rats
    Norihisa Kimura
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036 8562, Aomori Province, Japan
    Int J Mol Med 30:28-34. 2012
    ..Changes in the expression pattern of the ABC transporters, therefore, seem to be the key event in liver failure during liver regeneration...
  10. pmc Resection of a locally advanced hilar tumor and the hepatic artery after stepwise hepatic arterial embolization: a case report
    Takuya Miura
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:3587-90. 2008
    ..One month later, a left hepatectomy with hepatic arterial resection was successfully performed without any major complications...
  11. ncbi request reprint A bioartificial liver that combines plasma dialysis and whole liver perfusion
    Minoru Umehara
    Department of Surgery, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki, Aomori 036 8562, Japan
    Hepatogastroenterology 55:1216-21. 2008
    ..In this system, the patient's plasma was dialyzed with normal plasma recycled through the pig liver...
  12. ncbi request reprint Efficacy of donor splenocytes mixed with bone marrow cells for induction of tolerance in sublethally irradiated mice
    Naoki Hashimoto
    Second Department of Surgery, Hirosaki University School of Medicine, Japan
    Transpl Immunol 10:37-41. 2002
    ..In the present study, various components of SPLCs were purified or removed and were investigated their contribution for enhancement of bone marrow engraftment leading to donor-specific tolerance in sublethally irradiated mice...
  13. doi request reprint Sustained repression and translocation of Ntcp and expression of Mrp4 for cholestasis after rat 90% partial hepatectomy
    Takuya Miura
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036 8562, Japan
    J Hepatol 55:407-14. 2011
    ..To clarify the mechanism of persistent cholestasis after massive hepatectomy, the relationship between such cholestasis and the expression and localization of organic anion transporters for bile acids was examined in a rat model...
  14. ncbi request reprint Introduction of a simulation model for choledocho- and pancreaticojejunostomy
    Shunji Narumi
    Department of Gastrointestinal Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan
    Hepatogastroenterology 59:2333-4. 2012
    ..Our simulator enables surgeons and surgical residents to practice choledocho- and pancreaticojejunostomy through open or laparoscopic approaches...
  15. ncbi request reprint Decreased expression of claudin-1 is correlated with recurrence status in esophageal squamous cell carcinoma
    Keiichi Miyamoto
    Department of Pathology, Hirosaki University School of Medicine, Aomori, Japan
    Biomed Res 29:71-6. 2008
    ..0045). The results indicated that claudin-1 expression was correlated with the recurrence status and poor prognosis in esophageal cancer and claudin-1 expression may be a good indicator of recurrence in esophageal cancer...
  16. pmc Anti-apoptotic effect of claudin-1 in tamoxifen-treated human breast cancer MCF-7 cells
    Harue Akasaka
    Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine, Hirosaki 036 8562, Japan
    BMC Cancer 10:548. 2010
    ..However, the significance of claudin-1 expression in cancer cells is not well understood. Here, we showed for the first time the anti-apoptotic effect of claudin-1 in human breast cancer MCF-7 cells...
  17. pmc A case of invasive hemolymphangioma of the pancreas
    Yoshikazu Toyoki
    Department of Gastroenterological Surgery, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki, Aomori 0368652, Japan
    World J Gastroenterol 14:2932-4. 2008
    ..However, we experienced a case of hemolymphangioma of the pancreas with gastrointestinal bleeding due to invasion to the duodenum. This disease is a very rare entity, but should be considered when patients have gastrointestinal bleeding...
  18. ncbi request reprint [A case of recurrent intestinal GIST with long-term survival-beneficial effect of multimodality therapy using high-dose imatinib and surgery]
    Harue Akasaka
    Dept of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Japan
    Gan To Kagaku Ryoho 39:1975-7. 2012
    ..She continues to be an outpatient 7 years and 5 months after the first operation. The multimodality therapy of high-dose imatinib and surgery is beneficial for the control of recurrent intestinal GIST...
  19. doi request reprint Efficacy of adipose tissue-derived mesenchymal stem cells for fulminant hepatitis in mice induced by concanavalin A
    Norihito Kubo
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan
    J Gastroenterol Hepatol 27:165-72. 2012
    ..The aim of this study was to investigate a therapeutic effect of adipose tissue-derived mesenchymal stem cells (ASCs) on fulminant hepatitis induced by concanavalin A (ConA)...
  20. ncbi request reprint Attenuation of microcirculatory disturbance after liver ischemia by newly synthesized inflammatory cytokine suppressor, FR167653
    Makoto Takiguchi
    Second Department of Surgery, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki, Aomori, 036 8562 Japan
    Hepatogastroenterology 50:789-93. 2003
    ....
  21. ncbi request reprint Plasma exchange-based plasma recycling dialysis system as a potential platform for artificial liver support
    Akimasa Nishimura
    Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
    Artif Organs 30:629-33. 2006
    ..The safety of this system was demonstrated and the removal of toxic substances was significant. This study confirmed the clinical utility of this system as a platform for artificial liver support...
  22. ncbi request reprint Synergistic effect of cold and warm ischemia time on postoperative graft outcome in human liver transplantation
    Eishi Totsukali
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki Japan
    Hepatogastroenterology 51:1413-6. 2004
    ..The aim of this study was to determine whether simultaneously prolonged CIT and WIT was associated with early graft outcome after clinical OLT...
  23. ncbi request reprint Heterotopic gastrointestinal mucosa and pancreatic tissue in a retroperitoneal tumor
    Naoki Hashimoto
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki 036 8562, Japan
    J Hepatobiliary Pancreat Surg 13:351-4. 2006
    ..In addition, evidence of bleeding from the gastric mucosa was observed in the cystic tumor. External secretion from these tissues could have triggered the hemorrhage and expanded the tumor, possibly resulting in the back pain...
  24. pmc Hemosuccus pancreaticus: problems and pitfalls in diagnosis and treatment
    Yoshikazu Toyoki
    Department of Gastroenterological Surgery, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki, Aomori, Japan
    World J Gastroenterol 14:2776-9. 2008
    ....
  25. doi request reprint Characterization of heparan sulfate on hepatocytes in regenerating rat liver
    Akitoshi Kimura
    Department of Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, 036 8562, Japan
    J Hepatobiliary Pancreat Surg 15:608-14. 2008
    ..We investigated serial changes in GAGs, particularly heparan sulfate (HS), in proliferating hepatocytes...
  26. ncbi request reprint [Current status and treatment results of combined modality therapy for locally recurrent rectal cancer]
    Motoi Koyama
    Dept of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Japan
    Gan To Kagaku Ryoho 39:1911-3. 2012
    ..The aim of this study was to clarify the current status of combined modality therapy for locally recurrent rectal cancer...
  27. ncbi request reprint Decreased expression of claudin-1 correlates with recurrence status in breast cancer
    Satoko Morohashi
    Department of Pathology, Hirosaki University School of Medicine, Aomori 036 8562, Japan
    Int J Mol Med 20:139-43. 2007
    ..There was no significance between histological factors and CLDN4 expression. The results indicated that CLDN1 expression correlated with the recurrence status and malignant potential of breast cancer...
  28. ncbi request reprint Hepatic clearance improves after angioplasty of the hepatic vein
    S Narumi
    Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Transplant Proc 36:3091-2. 2004
    ..However, hepatic clearance of drugs quickly recovers after PTA. Close monitoring of immunosuppressive agents is fundamental at the time of angioplasty to avoid acute cellular rejection as developed in our two cases...
  29. doi request reprint The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer
    Yunyan Wu
    Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine, Hirosaki 036 8562, Japan
    Int J Oncol 41:1337-46. 2012
    ..These findings suggest that DEC1 plays an important role in the regulation of these EMT-related factors in pancreatic cancer...
  30. ncbi request reprint Epithelial cell adhesion molecule (EpCAM) overexpression is correlated with malignant potentials of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas
    Shinnosuke Yonaiyama
    Department of Pathology, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki, Aomori 036 8562, Japan
    Biomed Res 34:87-95. 2013
    ..877-64.919; P-value, 0.008). Our study is the first report to demonstrate that EpCAM overexpression is an independent factor for malignancy; therefore, EpCAM overexpression is thought to be a novel predictor of malignant IPMNs...
  31. ncbi request reprint Expression of MRP2 and MRP3 during liver regeneration after 90% partial hepatectomy in rats
    Tung Huei Chang
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Transplantation 77:22-7. 2004
    ..The aim of this study was to research whether there is any change in bilirubin excretion pattern during liver regeneration with reference to expression of MRP2 and MRP3...
  32. ncbi request reprint Usefulness of redox tolerance test in evaluating fatty liver
    E Totsuka
    Second Department of Surgery, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki, Aomori, 036 8562, Japan
    Hepatogastroenterology 48:184-7. 2001
    ..The study aimed to investigate the usefulness of redox tolerance test in diagnosing fatty liver...
  33. ncbi request reprint Efficacy of double filtration plasmapheretic cross-circulation using a high permeability membrane between totally hepatectomized dogs and donor pigs
    M Nara
    Second Department of Surgery, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    Transplantation 72:1736-42. 2001
    ..To solve these problems, we studied the effect of xenogeneic double filtration plasmapheretic cross-circulation (DFPCC) using a high performance semipermeable membrane on totally hepatectomized dogs...
  34. ncbi request reprint Influence of donor cardiopulmonary arrest in human liver transplantation: possible role of ischemic preconditioning
    E Totsuka
    Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Hepatology 31:577-80. 2000
    ..Although the liver function tests are elevated in an organ donor, the hepatic allograft is suitable for OLT if the liver damage is induced by brief donor cardiopulmonary arrest...
  35. ncbi request reprint Synergistic effect of cold and warm ischemia time on postoperative graft function and outcome in human liver transplantation
    E Totsuka
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Transplant Proc 36:1955-8. 2004
    ..2 U/L) and B (1931.3 +/- 362.6 U/L). The simultaneously prolonged cold and warm ischemia times significantly caused hepatic allograft injury and failure, suggesting some cumulative effects of CIT and WIT on postoperative graft function...
  36. ncbi request reprint Attenuation of canine warm ischemic small bowel injury by novel combination of nitric oxide donor, FK409, and cytokine suppressive anti-inflammatory agent FR167653
    E Totsuka
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Transplant Proc 36:1988-90. 2004
    ..In conclusion improvement of the microcirculation by FK409 and inhibition of cytokine release by FR167653 together attenuated warm ischemic small bowel injury...
  37. ncbi request reprint Analysis of clinical variables of donors and recipients with respect to short-term graft outcome in human liver transplantation
    E Totsuka
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Transplant Proc 36:2215-8. 2004
    ..This study was performed to analyze clinical characteristics of recipients and donors, which affect 30-day graft loss after OLT...
  38. doi request reprint Timing for orthotopic liver transplantation in children with biliary atresia: a single-center experience
    Y Toyoki
    Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
    Transplant Proc 40:2494-6. 2008
    ..The purpose of this study was to determine predictive prognostic factors for children with biliary atresia related to the timing for OLT within 15 months after hepatoportoenterostomy (HPE)...
  39. ncbi request reprint Intraoperative blood lactate level as an early predictor of initial graft function in human living donor liver transplantation
    A Nishimura
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
    Transplant Proc 36:2246-8. 2004
    ..This study was performed to investigate whether intraoperative changes in blood lactate levels after hepatic allograft reperfusion reflect initial graft function in living donor liver transplantation (LDLT)...
  40. ncbi request reprint Hepatic vein anastomotic stricture after living donor liver transplantation
    E Totsuka
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Transplant Proc 36:2252-4. 2004
    ..Balloon dilatation was useful and safe as the treatment, while problems have been reported after stent insertion in the hepatic vein...
  41. ncbi request reprint Primary immunosuppression regimen of rapid steroid withdrawal after living related liver transplantation: a single-center experience
    Y Toyoki
    Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Transplant Proc 36:2279-81. 2004
    ..Our immunosuppression regimen includes FK506 and steroid withdrawal by 30 days after transplantation. The aim of this study was to determine the outcomes of liver transplant, using this immunosuppressive regimen...
  42. ncbi request reprint In vitro evaluation of cross-circulation system using semipermeable membrane combined with whole liver perfusion
    M Umehara
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Transplant Proc 36:2349-51. 2004
    ..We developed a cross-circulation system, using a semipermeable membrane combined with whole liver perfusion. Detoxifying functions of the extracorporeal porcine liver and molecular movements across the membrane were evaluated in vitro...
  43. ncbi request reprint [Bevacizumab in combination with mFOLFOX6 or FOLFIRI for previously treated metastatic colorectal cancer]
    Motoi Koyama
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine
    Gan To Kagaku Ryoho 37:1069-73. 2010
    ..We confirmed that the chemotherapy including BV as second-line therapy had high antitumor effect and patient benefit...
  44. doi request reprint Usefulness of in-phase and out-of-phase magnetic resonance imaging for the detection of pancreatic lymphoepithelial cyst
    Daisuke Kudo
    Department of Surgery, Hirosaki University School of Medicine, Aomori, Japan
    Hepatogastroenterology 58:1403-5. 2011
    ..We herein report a case of pancreatic LEC which was preoperatively diagnosed by using in-phase and out-of-phase MRI and was successfully nucleated...
  45. doi request reprint Decrease of hepatic stellate cells in rats with enhanced sensitivity to clofibrate-induced hepatocarcinogenesis
    Daisuke Yamana
    Department of Biochemistry and Genome Biology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan
    Cancer Sci 102:735-41. 2011
    ..The expression levels of most HSC marker genes were low in both control and CF-treated rat livers. A possible link between HSC loss and the development of preneoplastic hepatic foci is discussed...
  46. doi request reprint Torsion of an accessory lobe of the liver in a child: report of a case
    Minoru Umehara
    Department of Pediatric Surgery, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki, Aomori, 036 8562, Japan
    Surg Today 39:80-2. 2009
    ..Torsion of an ALL should be included in the differential diagnosis of a patient with a history of omphalocele, who presents with acute abdominal symptoms...
  47. pmc Decreased postprandial gallbladder emptying in patients with black pigment stones
    Takakazu Sugo
    Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    World J Gastroenterol 14:2825-31. 2008
    ..To analyze gallbladder contractility in patients with black pigment stones (BPSs) and to compare this with patients with cholesterol stones (CSs) and healthy volunteers...
  48. ncbi request reprint Allogeneic chimerism established with a mixture of low dose bone marrow cells and splenocytes in sublethally irradiated mice
    Yukihiro Itabashi
    Second Department of Surgery, Hirosaki University School of Medicine, Japan
    Transpl Immunol 10:25-30. 2002
    ..In this study, we examined the effects of allogeneic chimerism after injecting donor bone marrow cells (BMCs) mixed with splenocytes (SPLCs) to the sublethally conditioned recipients...
  49. ncbi request reprint Living donor liver transplantation from 69 years and 9 months old donor: a case report
    Y Toyoki
    Department of Surgery, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki, Aomori, Japan
    Transplant Proc 35:64-5. 2003
  50. ncbi request reprint CD8 T cell of donor splenocyte mixed with bone marrow cells is more effective than CD4 T cell for induction of donor-specific tolerance in sublethally irradiated mice
    A Yoshida
    Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Transplant Proc 36:2418-22. 2004
    ..In this study, T-cell subsets CD4 (CD4SP) and CD8 (CD8SP) of donor SPLCs were investigated for their contribution to the enhancement of BMC engraftment leading to donor-specific tolerance in sublethally irradiated mice...
  51. ncbi request reprint Improved survival and ammonia metabolism by intraperitoneal transplantation of microencapsulated hepatocytes in totally hepatectomized rats
    Y Umehara
    Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Surgery 130:513-20. 2001
    ..In this study, 4 x 10(7) hepatocytes significantly prolonged the survival of rats that underwent hepatectomy and supported ammonia metabolism. Further development of this technique may permit its use in patients with hepatic failure...
  52. doi request reprint Living donor liver transplantation for a child with recurrent pediatric adult-type hepatocellular carcinoma
    M Nara
    Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
    Transplant Proc 40:2828-9. 2008
    ..There are few reports about liver transplantation for pediatric adult-type HCC. We experienced a case of living donor liver transplantation (LDLT) for a child with recurrent pediatric adult-type HCC...
  53. ncbi request reprint Influence of cold ischemia time and graft transport distance on postoperative outcome in human liver transplantation
    Eishi Totsuka
    Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Surg Today 32:792-9. 2002
    ....
  54. ncbi request reprint Hemolytic crisis with fulminant hepatic failure in Wilson disease without consanguinity
    Junichi Kitazawa
    Department of Pediatrics, Hirosaki City Hospital, Aomori, Japan
    Pediatr Int 46:726-9. 2004