Research Topics
| Yukoh SakataSummaryAffiliation: Healthcare Research Institute Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Characterization of dehydration behavior of untreated and pulverized creatine monohydrate powdersYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co, Ltd, 1624 Shimokotachi, Kodacho, Takatagun, Hiroshima 739 1195, Japan
Colloids Surf B Biointerfaces 35:185-91. 2004..Compared with pulverized creatine monohydrate, the particle size of untreated creatine monohydrate was significantly decreased by dehydration...
Evaluation of relationship between molecular behaviour and mechanical strength of pullulan filmsYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co Ltd, 1624 Shimokotachi, Kodacho, Akitakatashi, Hiroshima, Japan
Int J Pharm 374:33-8. 2009..The molecular behaviour of pullulan films due to film contraction and decreased water content were demonstrated by analysing the regression vector consisting of PC1 and PC2...- Effects of solid-state reaction between paracetamol and cloperastine hydrochloride on the pharmaceutical properties of their preparationsYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co, Ltd, 1624 Shimokotachi, Kodacho, Akitakatashi, Hiroshima 739 1195, Japan
Int J Pharm 335:12-9. 2007..The most probable interaction sites between PM and CLH were demonstrated by DSC analysis of a binary mixture of PM and CLH prepared by melt quenching... - Effect of pulverization and dehydration on the pharmaceutical properties of calcium lactate pentahydrate tabletsYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co, Ltd, Akitakata shi, Hiroshima 739 1195, Japan
Colloids Surf B Biointerfaces 51:149-56. 2006..Thus, the pharmaceutical properties of calcium lactate pentahydrate (CLP) tablets are affected both by pulverization and by the extent of dehydration of the bulk powder in the tablet formulation... - A novel white film for pharmaceutical coating formed by interaction of calcium lactate pentahydrate with hydroxypropyl methylcelluloseYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co Ltd, 1624 Shimokotachi, Kodacho, Akitakatashi, Hiroshima 739 1195, Japan
Int J Pharm 317:120-6. 2006..The most probable interaction sites between HPMC and CLP were demonstrated by FT-IR analysis of casting films consisting of HPMC, CLP and PVP... 
Effect of tablet geometrical structure on the dehydration of creatine monohydrate tablets, and their pharmaceutical propertiesYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co, Ltd, 1624 Shimokotachi, Kodacho, Takatagun, Hiroshima 739 1195, Japan
AAPS PharmSciTech 6:E527-35. 2005..The diffraction peaks of the (h00) planes and the micropore structure of the unpulverized monohydrate tablets were affected by pulverization and compression force, respectively...- Characterization of dehydration and hydration behavior of calcium lactate pentahydrate and its anhydrateYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co, Ltd, 1624 Shimokotachi, Kodacho, Akitakatashi, Hiroshima 739 1195, Japan
Colloids Surf B Biointerfaces 46:135-41. 2005..In contrast, the surface roughness of CLA was significantly decreased by hydration. The hydration of CLA followed a three-dimensional diffusion model (Ginstling-Brounshtein equation)... - Effect of pulverization of the bulk powder on the hydration of creatine anhydrate tablets and their pharmaceutical propertiesYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co, Ltd, 1624 Shimokotachi, Kodacho, Takatagun, Hiroshima 739 1195, Japan
Colloids Surf B Biointerfaces 46:92-100. 2005..Therefore, the reduction in tablet hardness depends not only on the hydration behavior but also on the crystal orientation of the CRA powder... - Effect of pulverization on hydration kinetic behaviors of creatine anhydrate powdersYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co Ltd, 1624 Shimokotachi, Kodacho, Takatagun, Hiroshima 739 1195, Japan
Colloids Surf B Biointerfaces 39:187-93. 2004..The transition rate constant of pulverized creatine anhydrate, calculated from the slope of the straight line, was about 1.34-1.36 times higher than that of unpulverized creatine anhydrate... - Improvement of sticking in tablet compaction for tocopherol acetateYukoh Sakata
Healthcare Research Institute, Wakunaga Pharmaceutical Co, Ltd, Japan
Drug Dev Ind Pharm 37:1049-59. 2011..The occurrence of sticking can be prevented not only by the addition of xylitol but also by changing the particle states of TA/FLR/xylitol blends... - Effect of dehydration and urea on stability of homosulfamine in solid statesShiho Kanou
Healthcare Research Institute, Wakunaga Pharmaceutical Co, Ltd, Shimokotachi, Kodacho, Akitakatashi, Hiroshima, Japan
Drug Dev Ind Pharm 34:771-80. 2008..The stability of homosulfamine was influenced not only by the presence of urea and dehydration but also by the surface state and particle size of the crystalline form... - Practical application to time indicator of a novel white film formed by interaction of calcium salts with hydroxypropyl methylcelluloseSumihiro Shiraishi
Research and Development Dept, Qualicaps Co, Ltd, 321 5 Ikezawacho, Yamatokoriyama, Nara 639 1032, Japan
Int J Pharm 383:255-63. 2010....