Research Topics
Genomes and GenesSpecies | Masako TakedaSummaryAffiliation: Health Sciences University of Hokkaido Country: Japan Publications
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Publications
Immunohistochemical detection of neurotrophin-3 and -4, and their receptors in mouse taste bud cellsMasako Takeda
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Ishikari, Hokkaido 061 0293, Japan
Arch Histol Cytol 68:393-403. 2005..5 and gustducin. We conclude that NT4 may exert trophic actions on all types of taste bud cells by binding to their TrkB receptors, and NT3 may also have a similar, though negligible role...
Expression of glial cell line-derived neurotrophic factor (GDNF) and GDNF family receptor alpha1 in mouse taste bud cells after denervationMasako Takeda
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Ishikari, Hokkaido, Japan
Anat Sci Int 80:105-10. 2005..Thus, GDNF- and GFRalpha1-immunoreactive taste bud cells after denervation vanished following the disappearance of the taste buds and reappeared at the same time as the taste buds reappeared...
Induction of apoptosis by colchicine in taste bud and epithelial cells of the mouse circumvallate papillaeM Takeda
Department of Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Ishikari, Hokkaido 061 0293, Japan
Cell Tissue Res 302:391-5. 2000..These results indicate that colchicine treatment of mice induces the apoptosis of taste bud and epithelial cells in the circumvallate papillae and dorsal epithelial cells around the circumvallate papillae...
Expression of GDNF and GFR alpha 1 in mouse taste bud cellsMasako Takeda
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Ishikari, Hokkaido 061 0293, Japan
J Comp Neurol 479:94-102. 2004..We conclude that GDNF in the type-II cells may exert trophic actions on type-I, -II, and -III taste bud cells by binding to their GFR alpha 1 receptors...
Expression of bHLH transcription factors NSCL1 and NSCL2 in the mouse olfactory systemYuko Suzuki
Department of Oral Histology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
Chem Senses 28:603-8. 2003..Moreover, the temporal pattern of expression suggests that NSCL1 and NSCL2 may function during development rather than in the adult stage...
Expression of BDNF and TrkB in mouse taste buds after denervation and in circumvallate papillae during developmentNobuhiko Uchida
Department of Oral Surgery, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Hokkaido, Japan
Arch Histol Cytol 66:17-25. 2003....
Expression of Hes6 and NeuroD in the olfactory epithelium, vomeronasal organ and non-sensory patchesYuko Suzuki
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
Chem Senses 28:197-205. 2003..At P3-P7, expression of NeuroD and Hes6 disappeared in the region corresponding to the presumptive non-sensory patches. The loss of these genes may stop the differentiation and may cause apoptosis of GBCs and ORNs...
Gene expression of beta-catenin is up-regulated in inner dental epithelium and enamel knots during molar tooth morphogenesis in the mouseNobuko Obara
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari Tobetsu, Hokkaido 061 0293, Japan
Cell Tissue Res 325:197-201. 2006..These findings raise the possibility that the up-regulation of the gene expression and the stabilization of the protein by Wnt signaling play a role in the regulation of the activities of beta-catenin in tooth morphogenesis...
Distinct expression pattern of insulin-like growth factor family in rodent taste budsYuko Suzuki
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
J Comp Neurol 482:74-84. 2005..The activity of these IGFs may be modulated through their interaction with IGFBP-2, -5, and 6...
Expression of neural cell-adhesion molecule mRNA during mouse molar tooth developmentNobuko Obara
Department of Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido, Japan
Arch Oral Biol 47:805-13. 2002..This study newly identifies the dental papilla and the stratum intermedium as NCAM-expressing sites...
Expression of NeuroD in the mouse taste budsYuko Suzuki
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
Cell Tissue Res 307:423-8. 2002..These results suggest that NeuroD is expressed in a mature cell type, type-II cells, but not in type-III cells...
Immunofluorescence detection of cadherins in mouse tooth germs during root developmentN Obara
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
Arch Oral Biol 44:415-21. 1999..These results suggest that the two cadherins play a part in root as well as in crown development, and indicate that the decrease in the amount of these molecules and the fragmentation of the epithelial root sheath are interrelated...
A comparative study of an olfactory epithelial area lacking olfactory neurons and a nearby presence of TGF-alpha-like immunoreactive olfactory neuronsY Suzuki
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
Anat Embryol (Berl) 203:239-47. 2001..Three-dimensional analysis of double-labeled (TGF-alpha, PGP9.5) serial sections revealed a unique relation among the epithelial patches, TGF-alpha-like immunoreactive neurons and olfactory epithelium...
Olfactory epithelium consisting of supporting cells and horizontal basal cells in the posterior nasal cavity of miceY Suzuki
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
Cell Tissue Res 299:313-25. 2000..This suggests that the epithelium consisting of supporting cells and horizontal basal cells is generated by the apoptotic death of olfactory cells and globose basal cells during postnatal development...
Bulbectomy of neonatal mice induces migration of basal cells from the olfactory epitheliumY Suzuki
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
Brain Res Dev Brain Res 108:295-8. 1998..At 1 month, not only basal cells but also olfactory cells and presumed supporting cells were involved in the clusters in the lamina propria and olfactory bulb, suggesting that migrated cells do not transform to other phenotypes...
Colchicine-induced cell death and proliferation in the olfactory epithelium and vomeronasal organ of the mouseY Suzuki
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
Anat Embryol (Berl) 198:43-51. 1998..In the next month, these regions became normal olfactory epithelium. This suggests that the globose basal cells in the surrounding normal olfactory epithelium might invade these regions to give rise to the olfactory cells...
Expression of insulin-like growth factor family in the rat olfactory epitheliumYuko Suzuki
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293 Japan
Anat Embryol (Berl) 205:401-5. 2002..IGFBPs may modulate IGF-I activity via their production by Bowman's glands, olfactory cells, and supporting cells themselves...
Effect of denervation on lymphocytes and dendritic cells in the rat circumvallate and foliate papillaeY Suzuki
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
Anat Embryol (Berl) 196:447-55. 1997..The finding suggests that gammadelta T lymphocytes and dendritic cells in the rat circumvallate and foliate papillae interact with each other to respond to changes such as the presence or absence of taste buds in the epithelium...
Distribution of the neural cell adhesion molecule (NCAM) during pre- and postnatal development of mouse incisorsN Obara
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
Anat Embryol (Berl) 195:193-202. 1997..These differences in the distribution of NCAM between the incisors and the molars might be related to the fact that rodent incisors continue to grow throughout the life of the animal...
Expression of E- and P-cadherin during tooth morphogenesis and cytodifferentiation of ameloblastsN Obara
Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
Anat Embryol (Berl) 197:469-75. 1998....
Expression of serine protease inhibitor 3 in ocular tissues in endotoxin-induced uveitis in ratA Takamiya
Department of Anatomy, Asahikawa Medical College, Asahikawa, Japan
Invest Ophthalmol Vis Sci 42:2427-33. 2001..To ascribe the serine protease inhibitor 3 (SPI-3) as an ocular acute inflammatory molecule and to clarify its producing cells in an endotoxin-induced uveitis (EIU) model...
Immunoelectron-microscopic study of Kit-expressing cells in the jejunum of wildtype and Ws/Ws ratsM Takeda
Department of Anatomy, Yamanashi Medical University, Tamaho, Japan
Cell Tissue Res 304:21-30. 2001..The present study suggests that Ws/Ws rats could provide an interesting model to investigate the physiological significance of pacemaker activity because they manifest a defect in IC-MY...
Inflammation induces serine protease inhibitor 3 expression in the rat pineal glandA Takamiya
Department of Anatomy, Asahikawa Medical College, 2 1 Midorigaoka Higashi Asahikawa, Hokkaido 078 8510, Japan
Neuroscience 113:387-94. 2002..We conclude that although the functional consequences of SPI-3 in the pineal gland during systemic inflammation are unknown, SPI-3 may have a crucial role in preventing some degenerative proteolysis induced by inflammatory stimuli...
Expression of the neural cell adhesion molecule (NCAM) during second- and third-molar development in the mouseN Obara
Department of Oral Anatomy, School of Dentistry, Higashi Nippon Gakuen University, Hokkaido, Japan
Anat Embryol (Berl) 188:13-20. 1993..On the other hand, the common sequence of NCAM expression in the tooth germs later than the cap stage suggests that NCAM plays an essential role in the formation of the basic structure of the teeth and periodontal tissues...
