Kazumi Osada

Summary

Affiliation: Health Sciences University of Hokkaido
Country: Japan

Publications

  1. doi request reprint Evaluation of the masking of dimethyl sulfide odors by citronellal, limonene and citral through the use of trained odor sensor mice
    Kazumi Osada
    Department of Oral Biology, Division of Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Chem Senses 38:57-65. 2013
  2. ncbi request reprint Citronellal ingestion decreases the appeal of male mouse urinary pheromone for female mice
    Kazumi Osada
    Department of Oral Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Biosci Biotechnol Biochem 76:1781-4. 2012
  3. doi request reprint The identification of attractive volatiles in aged male mouse urine
    Kazumi Osada
    Department of Oral Biology, Division of Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Chem Senses 33:815-23. 2008
  4. ncbi request reprint Experimental study of fatigue provoked by biotin deficiency in mice
    Kazumi Osada
    Department of Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Int J Vitam Nutr Res 74:334-40. 2004
  5. ncbi request reprint Effect of an orally ingested mugwort and mushroom extract mixture on urine odor from aged mice
    Kazumi Osada
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA mail
    Biosci Biotechnol Biochem 72:1249-56. 2008
  6. doi request reprint Alteration of mouse urinary odor by ingestion of the xenobiotic monoterpene citronellal
    Kazumi Osada
    Department of Oral Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Chem Senses 36:137-47. 2011
  7. doi request reprint Profiles of volatiles in male rat urine: the effect of puberty on the female attraction
    Kazumi Osada
    Division of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido, 061 0293, Japan
    Chem Senses 34:713-21. 2009
  8. pmc The scent of age
    Kazumi Osada
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Proc Biol Sci 270:929-33. 2003
  9. pmc Pyrazine analogues are active components of wolf urine that induce avoidance and freezing behaviours in mice
    Kazumi Osada
    Division of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido, Japan
    PLoS ONE 8:e61753. 2013
  10. doi request reprint Butylated hydroxytoluene is a ligand of urinary proteins derived from female mice
    Jae Kwak
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    Chem Senses 36:443-52. 2011

Detail Information

Publications13

  1. doi request reprint Evaluation of the masking of dimethyl sulfide odors by citronellal, limonene and citral through the use of trained odor sensor mice
    Kazumi Osada
    Department of Oral Biology, Division of Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Chem Senses 38:57-65. 2013
    ..The mice were similarly confused when confronted with citral (90 ppm) or limonene (3000 ppm). This study is the first to show that citrus odorants can mask the odor of DS, altering the behavioral responses of trained odor sensor mice...
  2. ncbi request reprint Citronellal ingestion decreases the appeal of male mouse urinary pheromone for female mice
    Kazumi Osada
    Department of Oral Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Biosci Biotechnol Biochem 76:1781-4. 2012
    ..A series of tests revealed that the female mice preferred voided urine odors from aged mice over those from younger adult mice. However, exogenous citronellal directly inhibited the advantage of the aged males with regard to attraction...
  3. doi request reprint The identification of attractive volatiles in aged male mouse urine
    Kazumi Osada
    Department of Oral Biology, Division of Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Chem Senses 33:815-23. 2008
    ..Our results suggest that inbred aged male mice develop an aging odor that is attractive to female mice in an experimental setting and that this attraction is due to increased mouse pheromone signaling...
  4. ncbi request reprint Experimental study of fatigue provoked by biotin deficiency in mice
    Kazumi Osada
    Department of Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Int J Vitam Nutr Res 74:334-40. 2004
    ..These results suggest that depression and/or fatigue are induced in mice by biotin deficiency...
  5. ncbi request reprint Effect of an orally ingested mugwort and mushroom extract mixture on urine odor from aged mice
    Kazumi Osada
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA mail
    Biosci Biotechnol Biochem 72:1249-56. 2008
    ..The results of three sets of generalization trials also strongly supported the results of the chemical studies. Together, these results suggest that ingested AAM decreased the intensity of odors associated with aging in mice...
  6. doi request reprint Alteration of mouse urinary odor by ingestion of the xenobiotic monoterpene citronellal
    Kazumi Osada
    Department of Oral Physiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Chem Senses 36:137-47. 2011
    ..This study is the first to show that ingestion of a xenobiotic can alter mouse urinary odor and confuse the behavioral responses of trained mice to age-related scents...
  7. doi request reprint Profiles of volatiles in male rat urine: the effect of puberty on the female attraction
    Kazumi Osada
    Division of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido, 061 0293, Japan
    Chem Senses 34:713-21. 2009
    ..Our results suggested that this attraction is due to an increased level of chemosignaling...
  8. pmc The scent of age
    Kazumi Osada
    Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
    Proc Biol Sci 270:929-33. 2003
    ..Fractionating and manipulating the levels of these compounds in the urine demonstrated that the mice can distinguish age based on variation in amounts of these specific compounds in the combined urine...
  9. pmc Pyrazine analogues are active components of wolf urine that induce avoidance and freezing behaviours in mice
    Kazumi Osada
    Division of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido, Japan
    PLoS ONE 8:e61753. 2013
    ..Although wolf urine is put to practical use to keep rabbits, rodents, deer and so on at bay, we are unaware of any prior behavioural studies or chemical analyses regarding the fear-inducing impact of wolf urine on laboratory mice...
  10. doi request reprint Butylated hydroxytoluene is a ligand of urinary proteins derived from female mice
    Jae Kwak
    Monell Chemical Senses Center, Philadelphia, PA 19104, USA
    Chem Senses 36:443-52. 2011
    ....
  11. ncbi request reprint Co-administration of proline and inorganic iron enhance the improvement of behavioral and hematological function of iron-deficient anemic rats
    Hideaki Kitajima
    Laboratory of Nutritional Biochemistry, School of Food and Nutritional Sciences, University of Shizuoka, 52 1 Yada, Shizuoka 422 8526, Japan
    J Nutr Sci Vitaminol (Tokyo) 49:7-12. 2003
    ..We propose that the combination of amino acid (especially proline) and inorganic iron might lead to an improvement in behavioral disorders caused by iron-deficient anemia...
  12. ncbi request reprint Age related decreases in neural sensitivity to NaCl in SHR-SP
    Kazumi Osada
    Laboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan
    J Vet Med Sci 65:313-7. 2003
    ..These results suggest that aged SHR-SP may be less able than young SHR-SPs to discriminate among higher concentrations of NaCl solutions...
  13. ncbi request reprint Olfactory fingerprints for major histocompatibility complex-determined body odors II: relationship among odor maps, genetics, odor composition, and behavior
    Michele L Schaefer
    Neuroscience Program, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Neurosci 22:9513-21. 2002
    ..These data on natural odors are consistent with the combinatorial code hypothesis and identify subsets of glomeruli that are apt to play a significant role in mediating individual recognition...