Affiliation: Hamamatsu University School of Medicine
- Tubulin tyrosination navigates the kinesin-1 motor domain to axonsYoshiyuki Konishi
Department of Molecular Anatomy, Hamamatsu University School of Medicine, Handayama, Shizuoka, Japan
Nat Neurosci 12:559-67. 2009..Our study identifies a molecular mechanism that discriminates the axonal microtubules from somatodendritic microtubules, as well as a previously unknown linkage between tubulin modification and polarized trafficking in neurons...
- Developments and applications of mass microscopyMitsutoshi Setou
Department of Molecular Anatomy, Hamamatsu University School of Medicine, 1 20 1 Handayama, Higashi ku, Hamamatsu, Shizuoka, 431 3192, Japan
Med Mol Morphol 43:1-5. 2010..In this Award Lecture Review, we focus on some of the recent developments in clinical applications to show how mass microscopy can be employed to assess medical molecular morphology...
- Axonal gradient of arachidonic acid-containing phosphatidylcholine and its dependence on actin dynamicsHyun Jeong Yang
Department of Cell Biology and Anatomy, Hamamatsu University School of Medicine, 1 20 1, Handayama, Hamamatsu 431 3192, Japan
J Biol Chem 287:5290-300. 2012..Inhibitors of actin dynamics (cytochalasin D and phallacidin) disrupted this gradient. This is the first report of the gradual distribution of AA-PC along the axon and its association with actin dynamics...
- Identification of tubulin deglutamylase among Caenorhabditis elegans and mammalian cytosolic carboxypeptidases (CCPs)Yoshishige Kimura
Department of Molecular Anatomy, Hamamatsu University School of Medicine, 1 20 1 Handayama, Hamamatsu, Shizuoka 431 3192, Japan
J Biol Chem 285:22936-41. 2010..Together, these data from two evolutionarily divergent systems identify C. elegans CCPP-6 and its mammalian ortholog CCP5 as a tubulin deglutamylase...