S Yamashita

Summary

Affiliation: Gunma University
Country: Japan

Publications

  1. ncbi request reprint Choline kinase from yeast
    S Yamashita
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Biochim Biophys Acta 1348:63-9. 1997
  2. ncbi request reprint Phosphatidylserine synthase from yeast
    S Yamashita
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Biochim Biophys Acta 1348:228-35. 1997
  3. ncbi request reprint Identification of the upstream activation sequences responsible for the expression and regulation of the PEM1 and PEM2 genes encoding the enzymes of the phosphatidylethanolamine methylation pathway in Saccharomyces cerevisiae
    T Kodaki
    Department of Biochemistry, Gunma University School of Medicine
    J Biochem 109:276-87. 1991
  4. ncbi request reprint Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli
    K Hosaka
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 264:2053-9. 1989
  5. ncbi request reprint Cloning and characterization of the SCS1 gene required for the expression of genes in yeast phospholipid synthesis
    K Hosaka
    Department of Biochemistry, Gunma University School of Medicine
    J Biochem 115:131-6. 1994
  6. ncbi request reprint Purification, cDNA cloning, and regulation of lysophospholipase from rat liver
    H Sugimoto
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 271:7705-11. 1996
  7. ncbi request reprint Primary structure of the yeast choline transport gene and regulation of its expression
    J Nikawa
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 265:15996-6003. 1990
  8. pmc Cloning, differential regulation and tissue distribution of alternatively spliced isoforms of ADP-ribosylation-factor-dependent phospholipase D from rat liver
    K Katayama
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Biochem J 329:647-52. 1998
  9. ncbi request reprint Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae
    J Nikawa
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 266:11184-91. 1991
  10. ncbi request reprint Characterization of the methyltransferases in the yeast phosphatidylethanolamine methylation pathway by selective gene disruption
    T Kodaki
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Eur J Biochem 185:243-51. 1989

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Choline kinase from yeast
    S Yamashita
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Biochim Biophys Acta 1348:63-9. 1997
    ..The expression of yeast choline kinase is transcriptionally repressed by myo-inositol and choline in a coordinate manner with other phospholipid-synthesizing enzymes in yeast...
  2. ncbi request reprint Phosphatidylserine synthase from yeast
    S Yamashita
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Biochim Biophys Acta 1348:228-35. 1997
    ..An octameric sequence, CATRTGAA (R = A or G), plays an important role in the conferral of the myo-inositol-choline transcriptional regulation...
  3. ncbi request reprint Identification of the upstream activation sequences responsible for the expression and regulation of the PEM1 and PEM2 genes encoding the enzymes of the phosphatidylethanolamine methylation pathway in Saccharomyces cerevisiae
    T Kodaki
    Department of Biochemistry, Gunma University School of Medicine
    J Biochem 109:276-87. 1991
    ....
  4. ncbi request reprint Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli
    K Hosaka
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 264:2053-9. 1989
    ..Thus, it is concluded that choline kinase is mono-cistronic and that the ethanolamine kinase activity is a second activity of choline kinase in the yeast...
  5. ncbi request reprint Cloning and characterization of the SCS1 gene required for the expression of genes in yeast phospholipid synthesis
    K Hosaka
    Department of Biochemistry, Gunma University School of Medicine
    J Biochem 115:131-6. 1994
    ..These results confirm and strengthen the conclusion that the SCS1/INO2 gene is required for expression of inositol-choline-regulated genes in phospholipid synthesis...
  6. ncbi request reprint Purification, cDNA cloning, and regulation of lysophospholipase from rat liver
    H Sugimoto
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 271:7705-11. 1996
    ..Thus a posttranscriptional control mechanism is present for the regulation of 24-kDa lysophospholipase...
  7. ncbi request reprint Primary structure of the yeast choline transport gene and regulation of its expression
    J Nikawa
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 265:15996-6003. 1990
    ..The CTR mRNA level was high in the exponential growth phase but decreased dramatically when cells entered the stationary phase. Similar control had been observed for some enzymes in yeast phospholipid synthesis...
  8. pmc Cloning, differential regulation and tissue distribution of alternatively spliced isoforms of ADP-ribosylation-factor-dependent phospholipase D from rat liver
    K Katayama
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Biochem J 329:647-52. 1998
    ..Both transcripts were hardly detectable in thymus, stomach, testis and muscle. Thus the two PLD1 isoforms were differently regulated and expressed in rat tissues...
  9. ncbi request reprint Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae
    J Nikawa
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 266:11184-91. 1991
    ..Northern blot analysis showed that ITR1 mRNA was much more abundant than ITR2 mRNA. The previously isolated myo-inositol transport mutant was determined to be defective in ITR1...
  10. ncbi request reprint Characterization of the methyltransferases in the yeast phosphatidylethanolamine methylation pathway by selective gene disruption
    T Kodaki
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Eur J Biochem 185:243-51. 1989
    ..These two enzymes accounted for all the activities in the yeast phosphatidylethanolamine methylation pathway...
  11. pmc Functional analysis of the regulatory region of the yeast phosphatidylserine synthase gene, PSS
    T Kodaki
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Bacteriol 173:7992-5. 1991
    ..The TATA box is located at positions -112 to -108. In addition, PSS contains a negative cis-acting sequence between UAS2 and the TATA box...
  12. ncbi request reprint Cloning and expression of cDNA encoding rat liver 60-kDa lysophospholipase containing an asparaginase-like region and ankyrin repeat
    H Sugimoto
    Department of Biochemistry, Gunma University School of Medicine, Maebashi 371 8511, Japan
    J Biol Chem 273:12536-42. 1998
    ....
  13. ncbi request reprint Identification of sna41 gene, which is the suppressor of nda4 mutation and is involved in DNA replication in Schizosaccharomyces pombe
    S Miyake
    Department of Biochemistry, Toho University School of Medicine, Tokyo, Japan
    Genes Cells 3:157-66. 1998
    ..These MCM proteins are thought to bind each other to make a heteromeric complex. The Nda4 protein of Schizosaccharomyces pombe is one of the MCM proteins and is involved in DNA replication...
  14. ncbi request reprint Cloning and sequence of the SCS3 gene which is required for inositol prototrophy in Saccharomyces cerevisiae
    K Hosaka
    Department of Biochemistry, Gunma University School of Medicine
    J Biochem 116:1317-21. 1994
    ..Disruption of the SCS3 locus caused myo-inositol auxotrophy. The gene appeared to be involved in the synthesis of inositol phospholipids from inositol but not in the control of inositol synthesis...
  15. ncbi request reprint Sequence, expression in Escherichia coli, and characterization of lysophospholipase II
    T Toyoda
    Department of Biochemistry, Gunma University School of Medicine, 3 39 22 Showamachi, Maebashi, Gunma 371 8511, Japan
    Biochim Biophys Acta 1437:182-93. 1999
    ..Northern blot analysis and reverse transcription-polymerase chain reaction revealed that lysophospholipase II transcript as well as lysophospholipase I transcript was widely distributed in mouse tissues...
  16. ncbi request reprint Molecular cloning of rat phosphatidylinositol synthase cDNA by functional complementation of the yeast Saccharomyces cerevisiae pis mutation
    S Tanaka
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    FEBS Lett 393:89-92. 1996
    ..The predicted protein sequence is highly homologous to the previously determined yeast phosphatidylinositol synthase sequence. The cDNA hybridized to a 1.7-kb mRNA that was abundantly expressed in rat brain and kidney...
  17. ncbi request reprint Cloning, expression, and characterization of a novel phospholipase D complementary DNA from rat brain
    T Kodaki
    Department of Biochemistry, Gunma University School of Medicine, Maebashi 371, Japan
    J Biol Chem 272:11408-13. 1997
    ..Only a negligible level was found in spleen and pancreas. Thus rPLD2 is a novel type of PLD dependent on phosphatidylinositol 4,5-bisphosphate, but not on the small GTP-binding proteins ADP-ribosylation factor 1 and RhoA...
  18. ncbi request reprint Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae
    Y Tsukagoshi
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Eur J Biochem 169:477-86. 1987
    ..coli) and DNA ligase (T4 phage), suggesting that these five enzymes are evolutionarily related. Statistically significant sequence homology was also noted between the human c-fos gene product and the enzyme...
  19. ncbi request reprint Cloning of a human choline kinase cDNA by complementation of the yeast cki mutation
    K Hosaka
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    FEBS Lett 304:229-32. 1992
    ..The human enzyme resembled the rat liver enzyme over the entire sequence. It also resembled the yeast enzyme in the carboxy-terminal region, but not much in the amino-terminal region...
  20. ncbi request reprint Differential distribution of mRNAs encoding phosphatidylinositol transfer proteins alpha and beta in the central nervous system of the rat
    H Imai
    Department of Neurosurgery, Gunma University School of Medicine, Maebashi, Japan
    Brain Res Mol Brain Res 46:256-64. 1997
    ..The distinct distribution of PI-TP alpha and PI-TP beta mRNAs suggests different functional roles for each of the gene products in the mature nervous system...
  21. ncbi request reprint Characterization of the transacylase activity of rat liver 60-kDa lysophospholipase-transacylase. Acyl transfer from the sn-2 to the sn-1 position
    H Sugimoto
    Department of Biochemistry, Gunma University School of Medicine, Maebashi 371 8511, Japan
    Biochim Biophys Acta 1438:264-72. 1999
    ..23 micromol/min/mg protein. Thus, 60-kDa lysophospholipase-transacylase may play a role in the synthesis of 1-arachidonoyl phosphatidylcholine needed for important cell functions, such as anandamide synthesis...
  22. ncbi request reprint Cloning and expression of human cDNA encoding phosphatidylinositol transfer protein beta
    S Tanaka
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Biochim Biophys Acta 1259:199-202. 1995
    ..1% identity to that of the beta isoform of rat phosphatidylinositol transfer protein. The cDNA hybridized to a 3.4-kb mRNA, which was widely expressed in various human tissues including brain...
  23. ncbi request reprint Identification of transcriptional enhancer factor-4 as a transcriptional modulator of CTP:phosphocholine cytidylyltransferase alpha
    H Sugimoto
    Department of Biochemistry, Gunma University School of Medicine, Maebashi 371-8511, Japan
    J Biol Chem 276:12338-44. 2001
    ..These results provide the first evidence that TEF-4 is an important regulator of CCTalpha gene expression...
  24. ncbi request reprint Identification of two Xenopus laevis genes, xMCM2 and xCDC46, with sequence homology to MCM genes involved in DNA replication
    S Miyake
    Department of Biochemistry, Toho University School of Medicine, Tokyo, Japan
    Gene 175:71-5. 1996
    ..When either xMCM2 or xCDC46 was immunoprecipitated with the specific Ab, the other was also co-precipitated. These results suggest that xMCM2 and xCDC46 physically interact with each other...
  25. ncbi request reprint Purification, characterization, and inhibition by phosphatidic acid of lysophospholipase transacylase from rat liver
    H Sugimoto
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 269:6252-8. 1994
    ..Although less potent, lysophosphatidic acid, palmitoyl-L-carnitine, and fatty acid were also inhibitory to the enzyme...
  26. ncbi request reprint Yeast phosphatidylethanolamine methylation pathway. Cloning and characterization of two distinct methyltransferase genes
    T Kodaki
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 262:15428-35. 1987
    ....
  27. ncbi request reprint IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae
    J Nikawa
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    Mol Microbiol 6:1441-6. 1992
    ..Disruption of the IRE1 locus caused myo-inositol auxotrophy. The IRE1 product is very likely a protein kinase required for myo-inositol synthesis...
  28. ncbi request reprint Possible physiological roles of proteolytic products of actin in neutrophils of patients with Behçet's disease
    S Yamashita
    Department of Biochemistry, Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo, Japan
    Biol Pharm Bull 24:733-7. 2001
    ..These results suggest that the increase of 42-merP and truncated actin in patients with Behçet's disease changes functions of neutrophils..
  29. ncbi request reprint Molecular cloning, characterization, and expression in Escherichia coli of a cDNA encoding mammalian choline kinase
    T Uchida
    Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan
    J Biol Chem 267:10156-62. 1992
    ..These results show that the cloned cDNA encodes one of the choline kinase isoforms present in mammalian tissues...
  30. ncbi request reprint Nestin expression in the kidney with an obstructed ureter
    T Sakairi
    Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Kidney Int 72:307-18. 2007
    ..Nestin expression was located in hypoxic regions of the kidney with an obstructed ureter. Our results indicate that nestin could be a novel marker for tubulointerstitial injury...
  31. ncbi request reprint [Effect of gallic acid derivatives on secretion of Th1 cytokines and Th2 cytokines from anti CD3-stimulated spleen cells]
    K Kato
    Department of Biochemistry, Faculty of Pharmaceutical Sciences, Hoshi University, 4-41, Ebara 2-chome, Shinagawa-ku, Tokyo 142-8501, Japan
    Yakugaku Zasshi 121:451-7. 2001
    ..In conclusion, it seemed that ethyl gallate was the most selective inhibitor for the secretion of Th2 cytokines among gallic acid derivatives used in this study...