H Sumino

Summary

Affiliation: Gunma University
Country: Japan

Publications

  1. ncbi request reprint [Investigation of atherosclerosis in postmenopausal women: alteration of atherosclerosis-associated factors and vascular atherosclerosis by oral and transdermal estrogen replacement]
    Hiroyuki Sumino
    Clinical Laboratory Center, Gunma University Hospital, Maebashi 371 8511, Japan
    Rinsho Byori 61:256-62. 2013
  2. ncbi request reprint Effects of hormone replacement therapy on serum angiotensin-converting enzyme activity and plasma bradykinin in postmenopausal women according to angiotensin-converting enzyme-genotype
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Showa machi, Maebashi, Japan
    Hypertens Res 26:53-8. 2003
  3. ncbi request reprint Effects of hormone replacement therapy on weight, abdominal fat distribution, and lipid levels in Japanese postmenopausal women
    H Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Int J Obes Relat Metab Disord 27:1044-51. 2003
  4. ncbi request reprint Hormone replacement therapy decreases insulin resistance and lipid metabolism in Japanese postmenopausal women with impaired and normal glucose tolerance
    Hiroyuki Sumino
    Second Department of Internal Medicine, Faculty of Medicine, Gunma University School of Medicine, Maebashi, Japan
    Horm Res 60:134-42. 2003
  5. ncbi request reprint Effects of conjugated equine estrogen and medroxyprogesterone acetate on lipoprotein(a) and other lipoproteins in japanese postmenopausal women with and without dyslipidemia
    Hiroyuki Sumino
    2nd Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Horm Res 62:1-9. 2004
  6. ncbi request reprint Effects of aging, menopause, and hormone replacement therapy on forearm skin elasticity in women
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Gunma, Japan
    J Am Geriatr Soc 52:945-9. 2004
  7. ncbi request reprint Effects of hormone replacement therapy on blood coagulation and fibrinolysis in hypertensive and normotensive postmenopausal women
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, 3 39 22 Showa mach, Maebashi 371 8511, Japan
    Thromb Res 115:359-66. 2005
  8. ncbi request reprint Effect of antihypertensive therapy on blood rheology in patients with essential hypertension
    H Sumino
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    J Int Med Res 33:170-7. 2005
  9. ncbi request reprint Effect of transdermal hormone replacement therapy on the monocyte chemoattractant protein-1 concentrations and other vascular inflammatory markers and on endothelial function in postmenopausal women
    Hiroyuki Sumino
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Am J Cardiol 96:148-53. 2005
  10. ncbi request reprint Conjugated estrogen plus medroxyprogesterone does not impair blood rheological properties in hypertensive postmenopausal women
    H Sumino
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi 371 8511, Japan
    Maturitas 53:306-14. 2006

Collaborators

Detail Information

Publications55

  1. ncbi request reprint [Investigation of atherosclerosis in postmenopausal women: alteration of atherosclerosis-associated factors and vascular atherosclerosis by oral and transdermal estrogen replacement]
    Hiroyuki Sumino
    Clinical Laboratory Center, Gunma University Hospital, Maebashi 371 8511, Japan
    Rinsho Byori 61:256-62. 2013
    ....
  2. ncbi request reprint Effects of hormone replacement therapy on serum angiotensin-converting enzyme activity and plasma bradykinin in postmenopausal women according to angiotensin-converting enzyme-genotype
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Showa machi, Maebashi, Japan
    Hypertens Res 26:53-8. 2003
    ..01, p < 0.01, and p < 0.01, respectively). These results suggest that the increased plasma bradykinin of PMW by HRT might not be induced solely by the reduction in serum ACE activity...
  3. ncbi request reprint Effects of hormone replacement therapy on weight, abdominal fat distribution, and lipid levels in Japanese postmenopausal women
    H Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Int J Obes Relat Metab Disord 27:1044-51. 2003
    ..To investigate the effects of hormone replacement therapy (HRT) on weight, abdominal fat distribution, and fasting lipid levels in Japanese postmenopausal women (PMW)...
  4. ncbi request reprint Hormone replacement therapy decreases insulin resistance and lipid metabolism in Japanese postmenopausal women with impaired and normal glucose tolerance
    Hiroyuki Sumino
    Second Department of Internal Medicine, Faculty of Medicine, Gunma University School of Medicine, Maebashi, Japan
    Horm Res 60:134-42. 2003
    ..To investigate the effect of combined estrogen and progesterone therapy on insulin resistance (IR) and carbohydrate and lipid metabolism in postmenopausal women (PMW) with impaired (IGT) and normal glucose tolerance (NGT)...
  5. ncbi request reprint Effects of conjugated equine estrogen and medroxyprogesterone acetate on lipoprotein(a) and other lipoproteins in japanese postmenopausal women with and without dyslipidemia
    Hiroyuki Sumino
    2nd Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Horm Res 62:1-9. 2004
    ..We investigated the effects of 12 months of treatment with conjugated equine estrogen and medroxyprogesterone acetate on lipoprotein(a) [Lp(a)] and other lipoproteins in Japanese postmenopausal women (PMW) with and without dyslipidemia...
  6. ncbi request reprint Effects of aging, menopause, and hormone replacement therapy on forearm skin elasticity in women
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Gunma, Japan
    J Am Geriatr Soc 52:945-9. 2004
    ..To investigate the decline per year in skin elasticity in postmenopausal women and how much hormone replacement therapy (HRT) increased elasticity over 12 months...
  7. ncbi request reprint Effects of hormone replacement therapy on blood coagulation and fibrinolysis in hypertensive and normotensive postmenopausal women
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, 3 39 22 Showa mach, Maebashi 371 8511, Japan
    Thromb Res 115:359-66. 2005
    ..Hypertension and estrogens are both prothrombotic. We investigated the effect of 12-month hormone replacement therapy (HRT) on hemostatic factors in mild to moderate essential hypertensive and normotensive postmenopausal women...
  8. ncbi request reprint Effect of antihypertensive therapy on blood rheology in patients with essential hypertension
    H Sumino
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    J Int Med Res 33:170-7. 2005
    ..These rheological differences could contribute to the decrease in cardiovascular disease seen when hypertensive patients are treated effectively...
  9. ncbi request reprint Effect of transdermal hormone replacement therapy on the monocyte chemoattractant protein-1 concentrations and other vascular inflammatory markers and on endothelial function in postmenopausal women
    Hiroyuki Sumino
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Am J Cardiol 96:148-53. 2005
    ..Transdermal HRT may exert an antiatherosclerotic effect by improving MCP-1 and cell adhesion molecule expression and endothelial function...
  10. ncbi request reprint Conjugated estrogen plus medroxyprogesterone does not impair blood rheological properties in hypertensive postmenopausal women
    H Sumino
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi 371 8511, Japan
    Maturitas 53:306-14. 2006
    ....
  11. ncbi request reprint Angiotensin II plays an important role in maintaining blood pressure in postmenopausal women receiving hormone replacement therapy
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Am J Hypertens 18:1340-6. 2005
    ....
  12. ncbi request reprint Effect of transdermal hormone replacement therapy on carotid artery wall thickness and levels of vascular inflammatory markers in postmenopausal women
    Hiroyuki Sumino
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan
    Hypertens Res 28:579-84. 2005
    ....
  13. ncbi request reprint Elevated arterial stiffness in postmenopausal women with osteoporosis
    H Sumino
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi 371 8511, Gunma, Japan
    Maturitas 55:212-8. 2006
    ..Osteoporosis and increased pulse wave velocity (PWV) are cardiovascular risk factors. We investigated the relationship between PWV and bone mass in the lumbar spine in postmenopausal women...
  14. ncbi request reprint Effects of hormone replacement therapy on office and ambulatory blood pressure in Japanese hypertensive postmenopausal women
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Hypertens Res 26:369-76. 2003
    ..We conclude that with respect to BP, HRT might not be harmful in hypertensive PMW whose BP has been well-controlled prior to the initiation of HRT, as well as in normotensive PMW...
  15. ncbi request reprint Hormone replacement therapy increases plasma level of angiotensin II in postmenopausal hypertensive women
    M Umeda
    Department of Laboratory Medicine, Gunma University School of Medicine, Maebashi, Japan
    Am J Hypertens 14:206-11. 2001
    ..Accordingly, the protective effect of HRT against cardiovascular disease in PMW can be provided by a decrease in ACE activity and an increase in bradykinin...
  16. ncbi request reprint Plasma adiponectin levels in post-menopausal women receiving hormone replacement therapy
    H Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Gunma, Japan
    J Int Med Res 32:639-45. 2004
    ..Our data suggest that circulating adiponectin may contribute to lipid homeostasis in PMW. Further studies are needed to elucidate the effects of HRT and oestrogen on adiponectin levels...
  17. pmc Effects of torasemide on cardiac sympathetic nerve activity and left ventricular remodelling in patients with congestive heart failure
    S Kasama
    Department of Cardiovascular Medicine, Gunma University School of Medicine, 3 39 15, Showa machi, Maebashi, Gunma 371 0034, Japan
    Heart 92:1434-40. 2006
    ..To determine the effect of torasemide, a loop diuretic with antialdosteronergic properties, compared with furosemide on cardiac sympathetic nerve activity in patients with congestive heart failure (CHF)...
  18. ncbi request reprint Lecithinized superoxide dismutase induces vasodilation; evidence of direct contribution of superoxide anions to modulating vascular tone
    T Nakamura
    The Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Life Sci 64:PL65-70. 1999
    ..The results of this study indicate that superoxide anions play a prominent role in modulating the vascular tone by enhancing the breakdown of nitric oxide...
  19. ncbi request reprint The somatostatin analog, octreotide, inhibits in vitro outgrowth of smooth muscle cells from canine coronary and carotid atherosclerotic plaque tissues
    H Sakamoto
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Res Commun Mol Pathol Pharmacol 101:25-34. 1998
    ....
  20. ncbi request reprint Decreased basal production of nitric oxide in patients with heart disease
    H Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Chest 113:317-22. 1998
    ..To determine whether the production of endogenous NO is correlated with any hemodynamic parameters, we measured the amount of NO released from the lung tissue of patients with heart disease...
  21. ncbi request reprint Troglitazone improves endothelial function and augments renal klotho mRNA expression in Otsuka Long-Evans Tokushima Fatty (OLETF) rats with multiple atherogenic risk factors
    T Yamagishi
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Hypertens Res 24:705-9. 2001
    ..These findings suggest that troglitazone protects the vascular endothelium against damage caused by the presence of multiple atherogenic factors...
  22. ncbi request reprint Impaired blood rheology and elevated remnant-like lipoprotein particle cholesterol in hypercholesterolaemic subjects
    M Nara
    Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Gunma, Japan
    J Int Med Res 37:308-17. 2009
    ..Impaired RBC deformability may contribute to impaired blood rheology associated with elevated RLP-C in hypercholesterolaemic subjects...
  23. pmc Comparative effects of valsartan and enalapril on cardiac sympathetic nerve activity and plasma brain natriuretic peptide in patients with congestive heart failure
    S Kasama
    Department of Cardiovascular Medicine, Gunma University School of Medicine, Maebashi, Japan
    Heart 92:625-30. 2006
    ....
  24. ncbi request reprint Immunosuppressive drugs inhibit the production of interleukin-6 and interleukin-8 in cultured cardiac myxoma cells
    H Sakamoto
    Second Department of Internal Medicine, Gunma University School of Medicine, Japan
    Res Commun Mol Pathol Pharmacol 97:60-6. 1997
    ..These results suggest that these newer immunosuppressive agents may be useful in reducing the production of IL-6 and IL-8 in patients with cardiac myxoma...
  25. ncbi request reprint Blood rheology and the low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio in dyslipidaemic and normolipidaemic subjects
    T Machida
    Clinical Laboratory Centre, Gunma University Graduate School of Medicine, Gunma, Japan
    J Int Med Res 38:1975-84. 2010
    ..These data suggest that an elevated LDL-C/HDL-C ratio may be helpful in predicting impaired blood rheology...
  26. ncbi request reprint Clinical features associated with circulating concentration of soluble leptin receptor in patients with diabetes
    N Kotajima
    Department of Laboratory Medicine and Medical Laboratory Centre, Gunma University School of Medicine, Gunma, Japan
    J Int Med Res 33:61-7. 2005
    ..Our results suggest that OB-Re might have an important influence on the biological activity of leptin in diabetic subjects...
  27. ncbi request reprint Combined primary aldosteronism and preclinical Cushing's syndrome: an unusual case presentation of adrenal adenoma
    T Honda
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Hypertens Res 24:723-6. 2001
    ..In patients with large aldosterone-producing adenoma, contralateral adrenal insufficiency should be anticipated after the removal of the tumor...
  28. ncbi request reprint Hormone replacement therapy in postmenopausal women with essential hypertension increases circulating plasma levels of bradykinin
    H Sumino
    Cardiovascular Hospital of Central Japan, Gunma
    Am J Hypertens 12:1044-7. 1999
    ..The increased bradykinin levels with a concomitant decrease of plasma ACE activity by HRT in hypertensive PMW seem to be beneficial for reducing the risk of CVD...
  29. ncbi request reprint Antihypertensive agents prevent nephrosclerosis and left ventricular hypertrophy induced in rats by prolonged inhibition of nitric oxide synthesis
    N Akuzawa
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Am J Hypertens 11:697-707. 1998
    ....
  30. ncbi request reprint Impaired blood rheology in critically ill patients in an intensive care unit
    Y Muranaka
    Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Gunma, Japan
    J Int Med Res 34:419-27. 2006
    ..Critically ill patients had impaired blood rheology, which could result from increased white blood cell count, potassium, creatinine and immunoglobulins and may be associated with the pathophysiology of the thromboembolic process...
  31. ncbi request reprint Reduction of viral myocarditis in mice lacking perforin
    H Koike
    Department of Laboratory Medicine, Gunma University School of Medicine, Maebashi, Japan
    Res Commun Mol Pathol Pharmacol 110:229-37. 2001
    ..Blockade of perforin gene expression at an early stage may limit viral myocarditis for therapeutic intervention...
  32. ncbi request reprint Relationships between blood rheology and age, body mass index, blood cell count, fibrinogen, and lipids in healthy subjects
    Koji Seki
    Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan
    Clin Hemorheol Microcirc 34:401-10. 2006
    ..This microchannel method may be useful to study blood rheology which may be associated with various risk factors of cardiovascular disorders...
  33. ncbi request reprint Different effects of oral conjugated estrogen and transdermal estradiol on arterial stiffness and vascular inflammatory markers in postmenopausal women
    Hiroyuki Sumino
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi 371 8511, Gunma, Japan
    Atherosclerosis 189:436-42. 2006
    ....
  34. ncbi request reprint Different effects of transdermal and oral hormone replacement therapy on the renin-angiotensin system, plasma bradykinin level, and blood pressure of normotensive postmenopausal women
    Junko Ichikawa
    Department of Anesthesiology, Tokyo Women s Medical University, Tokyo, Japan
    Am J Hypertens 19:744-9. 2006
    ....
  35. ncbi request reprint Oral administration of candesartan improves the survival of mice with viral myocarditis through modification of cardiac adiponectin expression
    Seiichiro Saegusa
    Department of General Medicine, Kanazawa Medical University, 1 1, Daigaku, Uchinada machi, Kahoku gun, Ishikawa, Japan
    Cardiovasc Drugs Ther 21:155-60. 2007
    ..We hypothesized that candesartan improves cardiac damage by inducing cardiac expression of adiponectin...
  36. ncbi request reprint Additive effects of spironolactone and candesartan on cardiac sympathetic nerve activity and left ventricular remodeling in patients with congestive heart failure
    Shu Kasama
    Department of Cardiovascular Medicine, Gunma University School of Medicine, Maebashi, Japan
    J Nucl Med 48:1993-2000. 2007
    ..We investigated the effects of the angiotensin-receptor blocker candesartan alone and in combination with spironolactone on CSNA in patients with congestive heart failure (CHF)...
  37. doi request reprint Relationship between carotid atherosclerosis and lumbar spine bone mineral density in postmenopausal women
    Hiroyuki Sumino
    Department of Nursing, Faculty of Nursing, Takasaki University of Health and Welfare, Takasaki, Japan
    Hypertens Res 31:1191-7. 2008
    ..Carotid atherosclerosis might be associated with lumbar spine bone mass in postmenopausal women, suggesting that postmenopausal women with osteoporosis may have more advanced carotid atherosclerosis than those with a normal bone mass...
  38. ncbi request reprint Hormone replacement therapy causes a decrease in hepatocyte growth factor in hypertensive women
    Kenichi Tamama
    The Department of Laboratory Medicine, Gunma University School of Medicine, Maebashi, Japan
    J Hypertens 21:1151-6. 2003
    ....
  39. ncbi request reprint Relationship between brachial arterial endothelial function and lumbar spine bone mineral density in postmenopausal women
    Hiroyuki Sumino
    Department of Nursing, Faculty of Nursing, Takasaki University of Health and Welfare, Takasaki, Japan
    Circ J 71:1555-9. 2007
    ..Osteoporosis and endothelial dysfunction have been associated with atherosclerosis. The correlation between brachial arterial endothelial function and lumbar spine bone mineral density (BMD) in postmenopausal women will be investigated...
  40. ncbi request reprint Effect of cerivastatin on endothelial dysfunction and aortic CD36 expression in diabetic hyperlipidemic rats
    Tetsuya Nakamura
    Clinical Investigation and Research Unit, Gunma University Hospital, Maebashi, Japan
    Hypertens Res 27:589-98. 2004
    ..Increased aortic expression of CD36 in response to cerivastatin could explain the reduction in serum triglyceride concentrations with statin therapy and may have pronounced beneficial effects in insulin-resistance syndromes...
  41. ncbi request reprint Effects of hormone replacement therapy on circulating docosahexaenoic acid and eicosapentaenoic acid levels in postmenopausal women
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi 371 8511, Japan
    Endocr J 50:51-9. 2003
    ..We propose that the increase in docosahexaenoic acid and eicosapentaenoic acid may be partially responsible for the beneficial mechanisms by which HRT induces an antiatherosclerotic effect in postmenopausal women...
  42. ncbi request reprint Production of endothelin-1 and big endothelin-1 by human cardiac myxoma cells--implications of the origin of myxomas--
    Hironosuke Sakamoto
    Department of General Practice Medicine, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Circ J 68:1230-2. 2004
    ..Although the origin of cardiac myxomas is still controversial, the 2 main hypotheses are that the tumor cells originate either from multipotential mesenchymal cells or from endocardial neural tissue...
  43. ncbi request reprint Reciprocal expression of vascular endothelial growth factor and nitric oxide synthase by coronary arterial wall cells during chronic inhibition of nitric oxide synthesis in rats
    Hironosuke Sakamoto
    Department of General Medicine, Gunma University School of Medicine, 3 39 22 Showa machi, Maebashi 371 8511, Japan
    Nephron 92:472-4. 2002
    ..These findings strongly suggest a reciprocal relation between VEGF and NO even in a rat model of chronic NO blockade...
  44. ncbi request reprint Production of nitric oxide, but not prostacyclin, is reduced in klotho mice
    Tetsuya Nakamura
    The Second Department of Internal Medicine, Gunma University School of Medicine, Maebaeshi, Japan
    Jpn J Pharmacol 89:149-56. 2002
    ..No immunostaining for NO synthase was noted in the aorta of kl/kl mice. The expression of the klotho gene product may have a role in the regulation of VEGF expression and is tightly linked to endothelial release of NO...
  45. ncbi request reprint Effects of hormone replacement therapy on left ventricular hypertrophy and growth-promoting factors in hypertensive postmenopausal women
    Yoshinori Miya
    Second Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Hypertens Res 25:153-9. 2002
    ..However, the effect of HRT on LVH did not appear to be associated with changes in growth-promoting factors, such as blood pressure, serum ACE activity, plasma aldosterone, and insulin resistance...
  46. ncbi request reprint Genetic influence of hormone-replacement therapy on venous thromboembolism
    Hiroyuki Sumino
    Lancet 362:1242. 2003
  47. ncbi request reprint [Study on blood rheology measured by MC-FAN]
    Koji Seki
    Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi 371 8511
    Rinsho Byori 51:770-5. 2003
    ..These results suggest that MC-FAN is useful to analyze blood rheology in pathophysiological conditions...
  48. ncbi request reprint Effects of aging and postmenopausal hypoestrogenism on skin elasticity and bone mineral density in Japanese women
    Hiroyuki Sumino
    Second Department of Internal Medicine, Gunma University School of Medicine, Japan
    Endocr J 51:159-64. 2004
    ..Additionally, decreased skin elasticity might serve as a predictor of bone loss in postmenopausal women...
  49. doi request reprint Brain atrophy in a murine model of chronic fatigue syndrome and beneficial effect of Hochu-ekki-to (TJ-41)
    Rui Chen
    Department of General Medicine, Kanazawa Medical University, 1 1 Daigaku, Uchinada machi, Kahoku gun, Ishikawa, 920 0293, Japan
    Neurochem Res 33:1759-67. 2008
    ..TJ-41 increased the daily running activity of the model, which was independent of brain recovery...
  50. ncbi request reprint [Hypertension in pregnancy]
    Hiroyuki Sumino
    Department of Internal Medicine, Cardiovascular Hospital of Central Japan
    Nihon Rinsho 62:431-4. 2004
  51. ncbi request reprint Evaluation of cardiac sympathetic nerve activity and left ventricular remodelling in patients with dilated cardiomyopathy on the treatment containing carvedilol
    Shu Kasama
    Department of Cardiovascular Medicine, Gunma University School of Medicine, 3 39 15, Showa machi, Maebashi, Gunma 371 0034, Japan
    Eur Heart J 28:989-95. 2007
    ..However, the influence of carvedilol on cardiac (123)I-meta-iodobenzylguanidine (MIBG) scintigraphic findings and left ventricular (LV) remodelling has not been determined in DCM patients...
  52. ncbi request reprint Reduced-energy diet improves survival of obese KKAy mice with viral myocarditis: induction of cardiac adiponectin expression
    Tsugiyasu Kanda
    Department of General Medicine, Kanazawa Medical University, 1 1 Daigaku, Uchinada machi, Kahoku gun, Ishikawa 920 0293, Japan
    Int J Cardiol 119:310-8. 2007
    ..The induction of adiponectin might provide benefit through a cardioprotective effect against acute heart failure due to viral myocarditis in obese subjects...
  53. ncbi request reprint Inhibition of cyclooxygenase-2 enhances myocardial damage in a mouse model of viral myocarditis
    Takashi Takahashi
    Department of a General Medicine, Kanazawa Medical University, Uchinada machi, Kahoku gun, Ishikawa 920 0293, Japan
    Life Sci 78:195-204. 2005
    ..These results suggest that inhibition of COX-2 may enhance myocardial damage through reciprocal cardiac expression of TNF-alpha and adiponectin in a mouse model of viral myocarditis...
  54. ncbi request reprint Impaired expression of cardiac adiponectin in leptin-deficient mice with viral myocarditis
    Takashi Takahashi
    Department of General Medicine, Kanazawa Medical University, Ishikawa, Japan
    Int Heart J 47:107-23. 2006
    ..These results suggest that impaired expression of cardiac adiponectin may contribute to the progression of viral myocarditis through enhanced expression of TNF-alpha under a leptin-deficient condition...
  55. ncbi request reprint Hypoadiponectinemia in bedridden female patients younger than 75
    Tsugiyasu Kanda
    J Am Geriatr Soc 53:2039-41. 2005