Yasuhiro Shibata

Summary

Affiliation: Gunma University
Country: Japan

Publications

  1. ncbi request reprint The evaluation of rat prostate blood flow using a laser speckle flowmetry: a comparative study using the microsphere method in castrated and androgen-replenished rats
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urol Res 32:44-8. 2004
  2. ncbi request reprint Dramatic remission of hormone refractory prostate cancer achieved with extract of the mushroom, Phellinus linteus
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urol Int 73:188-90. 2004
  3. ncbi request reprint Direct regulation of prostate blood flow by vascular endothelial growth factor and its participation in the androgenic regulation of prostate blood flow in vivo
    Yasuhiro Shibata
    Department of Urology, Graduate School of Medicine, Gunma University, 3 39 Showa machi, Maebashi, Gunma 371 8511, Japan
    Endocrinology 145:4507-12. 2004
  4. ncbi request reprint Participation of adrenomedullin and its relation with vascular endothelial growth factor in androgen regulation of prostatic blood flow in vivo
    Yasuhiro Shibata
    Department of Urology, Gunma University Graduate School of Medicine, Gunma, Japan
    Urology 68:1127-31. 2006
  5. ncbi request reprint Administration of extract of mushroom Phellinus linteus induces prostate enlargement with increase in stromal component in experimentally developed rat model of benign prostatic hyperplasia
    Yasuhiro Shibata
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Urology 66:455-60. 2005
  6. ncbi request reprint Androgen-dependent blood flow control and morphological changes of the capillaries in rat prostate
    Yoshihiro Ono
    Department of Urology, Gunma University School of Medicine, 3 39 22 Showa machi, Maebashi City, Gunma 371 8511, Japan
    Int J Androl 27:50-6. 2004
  7. ncbi request reprint Role of androgen on blood flow and capillary structure in rat seminal vesicles
    Yoshihiro Ono
    Department of Urology, Gunma University School of Medicine, Maebashi 371 8511, Japan
    Tohoku J Exp Med 202:193-201. 2004
  8. doi request reprint Effect of castration monotherapy on the levels of adrenal androgens in cancerous prostatic tissues
    Seiji Arai
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Steroids 76:301-8. 2011
  9. ncbi request reprint Effect of androgen concentration on seminal vesicle blood flow in rats-establishment of new highly sensitive simultaneous androgen measurement method
    Bunzo Kashiwagi
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Urology 66:218-23. 2005
  10. doi request reprint Influence of castration on bladder blood flow and function during the rapid phase of androgen deprivation
    Tomohiro Magari
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Scand J Urol 47:236-41. 2013

Collaborators

Detail Information

Publications27

  1. ncbi request reprint The evaluation of rat prostate blood flow using a laser speckle flowmetry: a comparative study using the microsphere method in castrated and androgen-replenished rats
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urol Res 32:44-8. 2004
    ....
  2. ncbi request reprint Dramatic remission of hormone refractory prostate cancer achieved with extract of the mushroom, Phellinus linteus
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urol Int 73:188-90. 2004
    ..We describe a hormone refractory prostate cancer patient with rapidly progressive bone metastasis who showed dramatic response to intake of an extract from the mushroom, Phellinus linteus...
  3. ncbi request reprint Direct regulation of prostate blood flow by vascular endothelial growth factor and its participation in the androgenic regulation of prostate blood flow in vivo
    Yasuhiro Shibata
    Department of Urology, Graduate School of Medicine, Gunma University, 3 39 Showa machi, Maebashi, Gunma 371 8511, Japan
    Endocrinology 145:4507-12. 2004
    ..Alternative treatment targeted toward anti-VEGF activity as a substitute for ordinary antiandrogenic therapy may be effective against prostate diseases, especially those with androgen-independent and hyperhemorrhagic status...
  4. ncbi request reprint Participation of adrenomedullin and its relation with vascular endothelial growth factor in androgen regulation of prostatic blood flow in vivo
    Yasuhiro Shibata
    Department of Urology, Gunma University Graduate School of Medicine, Gunma, Japan
    Urology 68:1127-31. 2006
    ..ADM is abundantly expressed in the prostate. We focused on ADM and evaluated its participation and relation with VEGF in androgen prostatic blood flow regulation using a castrated rat model...
  5. ncbi request reprint Administration of extract of mushroom Phellinus linteus induces prostate enlargement with increase in stromal component in experimentally developed rat model of benign prostatic hyperplasia
    Yasuhiro Shibata
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Urology 66:455-60. 2005
    ..However, until now, their effect on noncancerous benign prostate growth has not been examined...
  6. ncbi request reprint Androgen-dependent blood flow control and morphological changes of the capillaries in rat prostate
    Yoshihiro Ono
    Department of Urology, Gunma University School of Medicine, 3 39 22 Showa machi, Maebashi City, Gunma 371 8511, Japan
    Int J Androl 27:50-6. 2004
    ..These results clearly demonstrated that the androgen-dependent ultrastructural and morphological features in subepithelial capillaries revealed local microcirculatory conditions correlating the organ blood flow changes in VP...
  7. ncbi request reprint Role of androgen on blood flow and capillary structure in rat seminal vesicles
    Yoshihiro Ono
    Department of Urology, Gunma University School of Medicine, Maebashi 371 8511, Japan
    Tohoku J Exp Med 202:193-201. 2004
    ..These results indicate that the maintenance of the blood flow and morphological profiles in capillaries depend on androgen-supplementation levels in seminal vesicles...
  8. doi request reprint Effect of castration monotherapy on the levels of adrenal androgens in cancerous prostatic tissues
    Seiji Arai
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Steroids 76:301-8. 2011
    ..The levels of DHEA were high in PCa tissues, irrespective of ADT. We assumed that DHEA played a significant role in the synthesis of T and DHT in PCa tissues after ADT...
  9. ncbi request reprint Effect of androgen concentration on seminal vesicle blood flow in rats-establishment of new highly sensitive simultaneous androgen measurement method
    Bunzo Kashiwagi
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Urology 66:218-23. 2005
    ..To clarify the effect of androgen concentration on blood flow regulation in seminal vesicles and to identify the androgen most responsible for this effect...
  10. doi request reprint Influence of castration on bladder blood flow and function during the rapid phase of androgen deprivation
    Tomohiro Magari
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Scand J Urol 47:236-41. 2013
    ..This study examined the effects of androgen deprivation on bladder blood flow (BBF) and bladder function during the acute phase in castrated rats...
  11. doi request reprint Diagnostic significance of [-2]pro-PSA and prostate dimension-adjusted PSA-related indices in men with total PSA in the 2.0-10.0 ng/mL range
    Kazuto Ito
    Department of Urology, Gunma University Graduate School of Medicine, 3 39 22, Showa machi, Maebashi, Gunma, 371 8511, Japan
    World J Urol 31:305-11. 2013
    ....
  12. doi request reprint Rapamycin enhances docetaxel-induced cytotoxicity in a androgen-independent prostate cancer xenograft model by survivin downregulation
    Yasuyuki Morikawa
    Department of Urology, Gunma University Graduate School of Medicine, Maeabshi, Japan
    Biochem Biophys Res Commun 419:584-9. 2012
    ..Furthermore, we examined the relationship between these treatments and survivin, which is a member of the inhibitory apoptosis family...
  13. ncbi request reprint Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urology 62:942-6. 2003
    ..The effectiveness of antiandrogens on the control of hemorrhagic status in prostatic diseases has been previously reported...
  14. ncbi request reprint Changes in testosterone and dihydrotestosterone levels in male rat accessory sex organs, serum, and seminal fluid after castration: establishment of a new highly sensitive simultaneous androgen measurement method
    Bunzo Kashiwagi
    Department of Urology, Gunma University Graduated School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    J Androl 26:586-91. 2005
    ....
  15. doi request reprint Further evidence for null association of phenol sulfotransferase SULT1A1 polymorphism with prostate cancer risk: a case-control study of familial prostate cancer in a Japanese population
    Hidekazu Koike
    Maebashi, 3718511, Japan
    Int Urol Nephrol 40:947-51. 2008
    ..These findings suggested that genetic polymorphism of SULT1A1 might not be involved in genetic susceptibility to prostate cancer...
  16. doi request reprint New quantification method for estradiol in the prostatic tissues of benign prostatic hyperplasia using liquid chromatography-tandem mass spectrometry
    Seiji Arai
    Department of Urology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi 371 8511, Japan
    Steroids 75:13-9. 2010
    ..These results showed that our present method would be useful for elucidating the role of prostatic tissue E2 in the development of prostatic disorders with a small amount of tissue samples...
  17. ncbi request reprint Positive effect of prostaglandin on regulation of prostatic blood flow
    Bunzo Kashiwagi
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Urology 68:682-6. 2006
    ..We estimated that PGE2 participated in the signaling pathway of hormonal regulation of the prostatic blood flow...
  18. doi request reprint Luteinizing hormone (LH)-releasing hormone agonist reduces serum adrenal androgen levels in prostate cancer patients: implications for the effect of LH on the adrenal glands
    Masahiro Nishii
    Department of Urology, Gunma University Graduate School of Medicine, 3 39 22 Showamachi, Meabashi 371 8511, Japan
    J Androl 33:1233-8. 2012
    ..The long-term LH-RH agonist treatment reduced adrenal-originated adrenal androgens. LH receptors in the adrenal cortex cells of the reticular layer might account for the underlying mechanism of reduced adrenal androgens...
  19. ncbi request reprint Lead time of prostate cancer detected in population based screening for prostate cancer in Japan
    Kazuto Ito
    Department of Urology, Gunma University School of Medicine, Maebashi, Japan
    J Urol 178:1258-63; discussion 1263-4. 2007
    ..We clarified that lead time bias in screen detected prostate cancer is important for evaluating the outcome of any individual screening system...
  20. ncbi request reprint Placental growth factor gene expression in human prostate cancer and benign prostate hyperplasia
    Kazuhisa Matsumoto
    Department of Urology, Gunma University School of Medicine, 3 39 22 Showa machi, Maebashi, 371 8511, Gunma, Japan
    Anticancer Res 23:3767-73. 2003
    ..The presence of PlGF in human prostate has not been studied. In the current study, we investigated the gene expression profiles of PlGF in human prostate...
  21. doi request reprint Survivin is associated with cell proliferation and has a role in 1a,25-dihydroxyvitamin D3 induced cell growth inhibition in prostate cancer
    Hidekazu Koike
    Department of Urology, Gunma University Graduate School of Medicine, Gunma, Japan
    J Urol 185:1497-503. 2011
    ..We also examined the antitumor sensitization effect of survivin inhibition in 1a,25-dihydroxyvitamin D(3) treatment for prostate cancer cells...
  22. pmc Time-dependent effects of castration on the bladder function and histological changes in the bladder and blood vessels
    Tomohiro Magari
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi Department of Urology, Kurosawa Hospital, Takasaki, Japan
    Asian J Androl 16:457-60. 2014
    ..001). In conclusion, our findings indicate that castration does not alter BBF, but leads to histological changes in the bladder as well as its associated blood vessels. ..
  23. ncbi request reprint Pretreatment total testosterone levels in patients with prostate cancer in the past two decades in Japan
    Yoshitaka Sekine
    Department of Urology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma pref 371 8511, Japan
    Cancer Detect Prev 31:149-53. 2007
    ..We studied the association of pretreatment total testosterone levels with the clinical stage and histological grade of prostate cancer...
  24. ncbi request reprint [Cholesterol granuloma of the kidney: a case report]
    Kohei Okamoto
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi City, Gunma
    Nihon Hinyokika Gakkai Zasshi 102:586-90. 2011
    ..In this patient, the cholesterol granuloma could be barely distinguished from the cancer by using imaging techniques...
  25. ncbi request reprint Preparation of a single prostate needle biopsy specimen for histological diagnosis and RNA analysis
    Yoshitatsu Fukabori
    Department of Urology, Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi 321 0293, Japan
    J Urol 176:1204-7. 2006
    ..However, we developed a method for obtaining substances such as RNA and we also made pathological diagnosis possible from a single needle biopsy specimen, improving reliability...
  26. ncbi request reprint An innovative LC-MS/MS-based method for determining CYP 17 and CYP 19 activity in the adipose tissue of pre- and postmenopausal and ovariectomized women using 13C-labeled steroid substrates
    Toshihiko Kinoshita
    Department of Obstetrics and Gynecology T K, A T, N T, Toho University Medical Center Sakura Hospital, Chiba 285 8741, Japan Department of Analytical Research S H, Y W, H M, M O, ASKA Pharma Medical Co Ltd, Kawasaki 213 8522, Japan Department of Urology Y S, Gunma University Graduate School of Medicine, Maebashi 371 8511, Japan and Department of Clinical Analysis K Y, Tohoku Pharmaceutical University, Sendai 981 8558, Japan
    J Clin Endocrinol Metab 99:1339-47. 2014
    ..Does adipose tissue produce steroid hormones like an endocrine organ?..
  27. ncbi request reprint [Septic shock following flexible transurethral lithotripsy showing favourable response after multidisciplinary treatment mainly composed of recombinant thrombomodulin : a case report]
    Haruo Kato
    The Department of Urology, Gunma University Graduate School of Medicine, Japan
    Hinyokika Kiyo 58:499-502. 2012
    ..The risk of complications is expected to increase with the spread of f-TUL, and prompt action must be taken...