Yasuhiro Shibata

Summary

Affiliation: Gunma University
Country: Japan

Publications

  1. ncbi The evaluation of rat prostate blood flow using a laser speckle flowmetry: a comparative study using the microsphere method in castrated and androgen-replenished rats
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urol Res 32:44-8. 2004
  2. ncbi Participation of adrenomedullin and its relation with vascular endothelial growth factor in androgen regulation of prostatic blood flow in vivo
    Yasuhiro Shibata
    Department of Urology, Gunma University Graduate School of Medicine, Gunma, Japan
    Urology 68:1127-31. 2006
  3. ncbi Administration of extract of mushroom Phellinus linteus induces prostate enlargement with increase in stromal component in experimentally developed rat model of benign prostatic hyperplasia
    Yasuhiro Shibata
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Urology 66:455-60. 2005
  4. ncbi Dramatic remission of hormone refractory prostate cancer achieved with extract of the mushroom, Phellinus linteus
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urol Int 73:188-90. 2004
  5. ncbi Direct regulation of prostate blood flow by vascular endothelial growth factor and its participation in the androgenic regulation of prostate blood flow in vivo
    Yasuhiro Shibata
    Department of Urology, Graduate School of Medicine, Gunma University, 3 39 Showa machi, Maebashi, Gunma 371 8511, Japan
    Endocrinology 145:4507-12. 2004
  6. ncbi Role of androgen on blood flow and capillary structure in rat seminal vesicles
    Yoshihiro Ono
    Department of Urology, Gunma University School of Medicine, Maebashi 371 8511, Japan
    Tohoku J Exp Med 202:193-201. 2004
  7. ncbi Effect of castration monotherapy on the levels of adrenal androgens in cancerous prostatic tissues
    Seiji Arai
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Steroids 76:301-8. 2011
  8. ncbi Effect of androgen concentration on seminal vesicle blood flow in rats-establishment of new highly sensitive simultaneous androgen measurement method
    Bunzo Kashiwagi
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Urology 66:218-23. 2005
  9. ncbi Androgen-dependent blood flow control and morphological changes of the capillaries in rat prostate
    Yoshihiro Ono
    Department of Urology, Gunma University School of Medicine, 3 39 22 Showa machi, Maebashi City, Gunma 371 8511, Japan
    Int J Androl 27:50-6. 2004
  10. ncbi Rapamycin enhances docetaxel-induced cytotoxicity in a androgen-independent prostate cancer xenograft model by survivin downregulation
    Yasuyuki Morikawa
    Department of Urology, Gunma University Graduate School of Medicine, Maeabshi, Japan
    Biochem Biophys Res Commun 419:584-9. 2012

Collaborators

Detail Information

Publications24

  1. ncbi The evaluation of rat prostate blood flow using a laser speckle flowmetry: a comparative study using the microsphere method in castrated and androgen-replenished rats
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urol Res 32:44-8. 2004
    ....
  2. ncbi Participation of adrenomedullin and its relation with vascular endothelial growth factor in androgen regulation of prostatic blood flow in vivo
    Yasuhiro Shibata
    Department of Urology, Gunma University Graduate School of Medicine, Gunma, Japan
    Urology 68:1127-31. 2006
    ..ADM is abundantly expressed in the prostate. We focused on ADM and evaluated its participation and relation with VEGF in androgen prostatic blood flow regulation using a castrated rat model...
  3. ncbi Administration of extract of mushroom Phellinus linteus induces prostate enlargement with increase in stromal component in experimentally developed rat model of benign prostatic hyperplasia
    Yasuhiro Shibata
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Urology 66:455-60. 2005
    ..However, until now, their effect on noncancerous benign prostate growth has not been examined...
  4. ncbi Dramatic remission of hormone refractory prostate cancer achieved with extract of the mushroom, Phellinus linteus
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urol Int 73:188-90. 2004
    ..We describe a hormone refractory prostate cancer patient with rapidly progressive bone metastasis who showed dramatic response to intake of an extract from the mushroom, Phellinus linteus...
  5. ncbi Direct regulation of prostate blood flow by vascular endothelial growth factor and its participation in the androgenic regulation of prostate blood flow in vivo
    Yasuhiro Shibata
    Department of Urology, Graduate School of Medicine, Gunma University, 3 39 Showa machi, Maebashi, Gunma 371 8511, Japan
    Endocrinology 145:4507-12. 2004
    ..Alternative treatment targeted toward anti-VEGF activity as a substitute for ordinary antiandrogenic therapy may be effective against prostate diseases, especially those with androgen-independent and hyperhemorrhagic status...
  6. ncbi Role of androgen on blood flow and capillary structure in rat seminal vesicles
    Yoshihiro Ono
    Department of Urology, Gunma University School of Medicine, Maebashi 371 8511, Japan
    Tohoku J Exp Med 202:193-201. 2004
    ..These results indicate that the maintenance of the blood flow and morphological profiles in capillaries depend on androgen-supplementation levels in seminal vesicles...
  7. ncbi Effect of castration monotherapy on the levels of adrenal androgens in cancerous prostatic tissues
    Seiji Arai
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Steroids 76:301-8. 2011
    ..The levels of DHEA were high in PCa tissues, irrespective of ADT. We assumed that DHEA played a significant role in the synthesis of T and DHT in PCa tissues after ADT...
  8. ncbi Effect of androgen concentration on seminal vesicle blood flow in rats-establishment of new highly sensitive simultaneous androgen measurement method
    Bunzo Kashiwagi
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Urology 66:218-23. 2005
    ..To clarify the effect of androgen concentration on blood flow regulation in seminal vesicles and to identify the androgen most responsible for this effect...
  9. ncbi Androgen-dependent blood flow control and morphological changes of the capillaries in rat prostate
    Yoshihiro Ono
    Department of Urology, Gunma University School of Medicine, 3 39 22 Showa machi, Maebashi City, Gunma 371 8511, Japan
    Int J Androl 27:50-6. 2004
    ..These results clearly demonstrated that the androgen-dependent ultrastructural and morphological features in subepithelial capillaries revealed local microcirculatory conditions correlating the organ blood flow changes in VP...
  10. ncbi Rapamycin enhances docetaxel-induced cytotoxicity in a androgen-independent prostate cancer xenograft model by survivin downregulation
    Yasuyuki Morikawa
    Department of Urology, Gunma University Graduate School of Medicine, Maeabshi, Japan
    Biochem Biophys Res Commun 419:584-9. 2012
    ..Furthermore, we examined the relationship between these treatments and survivin, which is a member of the inhibitory apoptosis family...
  11. ncbi Changes in testosterone and dihydrotestosterone levels in male rat accessory sex organs, serum, and seminal fluid after castration: establishment of a new highly sensitive simultaneous androgen measurement method
    Bunzo Kashiwagi
    Department of Urology, Gunma University Graduated School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    J Androl 26:586-91. 2005
    ....
  12. ncbi Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate
    Yasuhiro Shibata
    Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Urology 62:942-6. 2003
    ..The results support the basic aspects of the advantage of preoperative treatment with CMA, flutamide, and bicalutamide, similar to finasteride, in reducing perioperative hemorrhage...
  13. ncbi Further evidence for null association of phenol sulfotransferase SULT1A1 polymorphism with prostate cancer risk: a case-control study of familial prostate cancer in a Japanese population
    Hidekazu Koike
    Maebashi, 3718511, Japan
    Int Urol Nephrol 40:947-51. 2008
    ..These findings suggested that genetic polymorphism of SULT1A1 might not be involved in genetic susceptibility to prostate cancer...
  14. ncbi New quantification method for estradiol in the prostatic tissues of benign prostatic hyperplasia using liquid chromatography-tandem mass spectrometry
    Seiji Arai
    Department of Urology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi 371 8511, Japan
    Steroids 75:13-9. 2010
    ..These results showed that our present method would be useful for elucidating the role of prostatic tissue E2 in the development of prostatic disorders with a small amount of tissue samples...
  15. ncbi Positive effect of prostaglandin on regulation of prostatic blood flow
    Bunzo Kashiwagi
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi, Japan
    Urology 68:682-6. 2006
    ..We estimated that PGE2 participated in the signaling pathway of hormonal regulation of the prostatic blood flow...
  16. ncbi Diagnostic significance of [-2]pro-PSA and prostate dimension-adjusted PSA-related indices in men with total PSA in the 2.0-10.0 ng/mL range
    Kazuto Ito
    Department of Urology, Gunma University Graduate School of Medicine, 3 39 22, Showa machi, Maebashi, Gunma, 371 8511, Japan
    World J Urol 31:305-11. 2013
    ....
  17. ncbi Luteinizing hormone (LH)-releasing hormone agonist reduces serum adrenal androgen levels in prostate cancer patients: implications for the effect of LH on the adrenal glands
    Masahiro Nishii
    Department of Urology, Gunma University Graduate School of Medicine, 3 39 22 Showamachi, Meabashi 371 8511, Japan
    J Androl 33:1233-8. 2012
    ..The long-term LH-RH agonist treatment reduced adrenal-originated adrenal androgens. LH receptors in the adrenal cortex cells of the reticular layer might account for the underlying mechanism of reduced adrenal androgens...
  18. ncbi Survivin is associated with cell proliferation and has a role in 1a,25-dihydroxyvitamin D3 induced cell growth inhibition in prostate cancer
    Hidekazu Koike
    Department of Urology, Gunma University Graduate School of Medicine, Gunma, Japan
    J Urol 185:1497-503. 2011
    ..We also examined the antitumor sensitization effect of survivin inhibition in 1a,25-dihydroxyvitamin D(3) treatment for prostate cancer cells...
  19. ncbi Lead time of prostate cancer detected in population based screening for prostate cancer in Japan
    Kazuto Ito
    Department of Urology, Gunma University School of Medicine, Maebashi, Japan
    J Urol 178:1258-63; discussion 1263-4. 2007
    ..We clarified that lead time bias in screen detected prostate cancer is important for evaluating the outcome of any individual screening system...
  20. ncbi Placental growth factor gene expression in human prostate cancer and benign prostate hyperplasia
    Kazuhisa Matsumoto
    Department of Urology, Gunma University School of Medicine, 3-39-22 Showa-machi, Maebashi, 371-8511, Gunma, Japan
    Anticancer Res 23:3767-73. 2003
    ..01). CONCLUSION: PlGF mRNA was expressed in human prostate. Significantly lower levels of PlGF in CAP in comparison with those in BPH or CAP-Tx suggested that PlGF might have effects on vasculogenesis and angiogenesis in prostate disease...
  21. ncbi Pretreatment total testosterone levels in patients with prostate cancer in the past two decades in Japan
    Yoshitaka Sekine
    Department of Urology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma pref 371 8511, Japan
    Cancer Detect Prev 31:149-53. 2007
    ..We studied the association of pretreatment total testosterone levels with the clinical stage and histological grade of prostate cancer...
  22. ncbi [Cholesterol granuloma of the kidney: a case report]
    Kohei Okamoto
    Department of Urology, Gunma University Graduate School of Medicine, Maebashi City, Gunma
    Nihon Hinyokika Gakkai Zasshi 102:586-90. 2011
    ..In this patient, the cholesterol granuloma could be barely distinguished from the cancer by using imaging techniques...
  23. ncbi Preparation of a single prostate needle biopsy specimen for histological diagnosis and RNA analysis
    Yoshitatsu Fukabori
    Department of Urology, Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi 321 0293, Japan
    J Urol 176:1204-7. 2006
    ..However, we developed a method for obtaining substances such as RNA and we also made pathological diagnosis possible from a single needle biopsy specimen, improving reliability...
  24. ncbi [Septic shock following flexible transurethral lithotripsy showing favourable response after multidisciplinary treatment mainly composed of recombinant thrombomodulin : a case report]
    Haruo Kato
    The Department of Urology, Gunma University Graduate School of Medicine, Japan
    Hinyokika Kiyo 58:499-502. 2012
    ..The risk of complications is expected to increase with the spread of f-TUL, and prompt action must be taken...