Tsugio Nakazawa

Summary

Affiliation: Gunma University
Country: Japan

Publications

  1. ncbi [Trend of asthma mortality in Japan]
    Tsugio Nakazawa
    School of Health Sciences, Faculty of Medicine, Gunma University
    Arerugi 53:1112-8. 2004
  2. ncbi Glutathione redox regulates lipopolysaccharide-induced IL-12 production through p38 mitogen-activated protein kinase activation in human monocytes: role of glutathione redox in IFN-gamma priming of IL-12 production
    Mitsuyoshi Utsugi
    First Department of Internal Medicine, Faculty of Medicine, School of Medicine, Gunma University, Maebashi, Japan
    J Leukoc Biol 71:339-47. 2002
  3. ncbi DNA microarray genotyping of N-acetyltransferase 2 polymorphism using carbodiimide as the linker for assessment of isoniazid hepatotoxicity
    Yasuo Shimizu
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma 371 8511, Japan
    Tuberculosis (Edinb) 86:374-81. 2006
  4. ncbi Effect of Y-27632 on release of cytokines from peripheral T cells in asthmatic patients and normal subjects
    Masayuki Aihara
    First Department of Internal Medicine, Faculty of Medicine, School of Medicine, Gunma University, 3 39 15, Showa machi, Maebashi, Gunma 371 8511, Japan
    Int Immunopharmacol 4:557-61. 2004
  5. ncbi Comparison of effects of Y-27632 and Isoproterenol on release of cytokines from human peripheral T cells
    Masayuki Aihara
    First Department of Internal Medicine, Gunma University Faculty of Medicine, School of Medicine, 3 39 15, Showa machi, Maebashi, Gunma 371 8511, Japan
    Int Immunopharmacol 3:1619-25. 2003
  6. ncbi Safety and efficacy of extracorporeal granulocyte and monocyte adsorption apheresis in patients with severe persistent bronchial asthma
    Tamotsu Ishizuka
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, 371 8511, Japan
    Inflammation 29:9-16. 2005
  7. ncbi C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts
    Mitsuyoshi Utsugi
    First Department of Internal Medicine, Gunma University Faculty of Medicine, School of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma, 371 8511, Japan
    Am J Respir Cell Mol Biol 28:754-61. 2003
  8. ncbi Toll-like receptor 4 surface expression on human monocytes and B cells is modulated by IL-2 and IL-4
    Yoshinori Mita
    First Department of Internal Medicine, Faculty of Medicine, Gunma University, 3 39 15, Showa machi, Maebashi, Gunma 371 8511, Japan
    Immunol Lett 81:71-5. 2002
  9. ncbi c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production
    Mitsuyoshi Utsugi
    First Department of Internal Medicine, Gunma University Faculty of Medicine, School of Medicine, Maebashi, Japan
    J Immunol 171:628-35. 2003
  10. ncbi 8-Bromo-cAMP decreases the Ca2+ sensitivity of airway smooth muscle contraction through a mechanism distinct from inhibition of Rho-kinase
    Katsuaki Endou
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Japan
    Am J Physiol Lung Cell Mol Physiol 287:L641-8. 2004

Detail Information

Publications15

  1. ncbi [Trend of asthma mortality in Japan]
    Tsugio Nakazawa
    School of Health Sciences, Faculty of Medicine, Gunma University
    Arerugi 53:1112-8. 2004
  2. ncbi Glutathione redox regulates lipopolysaccharide-induced IL-12 production through p38 mitogen-activated protein kinase activation in human monocytes: role of glutathione redox in IFN-gamma priming of IL-12 production
    Mitsuyoshi Utsugi
    First Department of Internal Medicine, Faculty of Medicine, School of Medicine, Gunma University, Maebashi, Japan
    J Leukoc Biol 71:339-47. 2002
    ....
  3. ncbi DNA microarray genotyping of N-acetyltransferase 2 polymorphism using carbodiimide as the linker for assessment of isoniazid hepatotoxicity
    Yasuo Shimizu
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma 371 8511, Japan
    Tuberculosis (Edinb) 86:374-81. 2006
    ..These findings suggest that our microarray may be clinically useful for predicting drug reactions to INH...
  4. ncbi Effect of Y-27632 on release of cytokines from peripheral T cells in asthmatic patients and normal subjects
    Masayuki Aihara
    First Department of Internal Medicine, Faculty of Medicine, School of Medicine, Gunma University, 3 39 15, Showa machi, Maebashi, Gunma 371 8511, Japan
    Int Immunopharmacol 4:557-61. 2004
    ..Our data suggested that the involvement of RhoA/ROCK pathway in TCR-mediated secretion of IFN-gamma and IL-4 in patients with bronchial asthma differed from that in healthy persons...
  5. ncbi Comparison of effects of Y-27632 and Isoproterenol on release of cytokines from human peripheral T cells
    Masayuki Aihara
    First Department of Internal Medicine, Gunma University Faculty of Medicine, School of Medicine, 3 39 15, Showa machi, Maebashi, Gunma 371 8511, Japan
    Int Immunopharmacol 3:1619-25. 2003
    ..It is suggested that the RhoA/ROCK system plays an important role in the release of Th-1 cytokines and is partially involved in the release of Th-2 cytokines from human T cells activated through T cell receptor (TCR)...
  6. ncbi Safety and efficacy of extracorporeal granulocyte and monocyte adsorption apheresis in patients with severe persistent bronchial asthma
    Tamotsu Ishizuka
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, 371 8511, Japan
    Inflammation 29:9-16. 2005
    ..4% after the therapy. This therapy was not harmful for patients with severe persistent asthma. A placebo-controlled study will be desired to evaluate the efficacy of this nonpharmacological strategy accurately...
  7. ncbi C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts
    Mitsuyoshi Utsugi
    First Department of Internal Medicine, Gunma University Faculty of Medicine, School of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma, 371 8511, Japan
    Am J Respir Cell Mol Biol 28:754-61. 2003
    ..These results suggest that TGF-beta1-induced CTGF mRNA expression is mediated through the JNK-dependent pathway, whereas p38 MAP kinase and ERK pathways minimally contribute...
  8. ncbi Toll-like receptor 4 surface expression on human monocytes and B cells is modulated by IL-2 and IL-4
    Yoshinori Mita
    First Department of Internal Medicine, Faculty of Medicine, Gunma University, 3 39 15, Showa machi, Maebashi, Gunma 371 8511, Japan
    Immunol Lett 81:71-5. 2002
    ....
  9. ncbi c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production
    Mitsuyoshi Utsugi
    First Department of Internal Medicine, Gunma University Faculty of Medicine, School of Medicine, Maebashi, Japan
    J Immunol 171:628-35. 2003
    ..Our findings indicate that JNK negatively affects LPS-induced IL-12 production from human macrophages, and that glutathione redox regulates LPS-induced IL-12 production through the opposite control of JNK and p38 MAP kinase activation...
  10. ncbi 8-Bromo-cAMP decreases the Ca2+ sensitivity of airway smooth muscle contraction through a mechanism distinct from inhibition of Rho-kinase
    Katsuaki Endou
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Japan
    Am J Physiol Lung Cell Mol Physiol 287:L641-8. 2004
    ....
  11. ncbi Effects of fluticasone propionate on bone mineral density in patients with persistent bronchial asthma
    Tamotsu Ishizuka
    First Department of Internal Medicine, Gunma University School of Medicine, Maebashi
    Intern Med 41:798-804. 2002
    ..CONCLUSION: These results indicate that the continuous administration of OCS in patients with severe persistent asthma, particularly in older patients, may affect BMD in the short term even at a low OCS dose...
  12. ncbi Epidemiology of asthma
    Sohei Makino
    Dokkyo University School of Medicine
    Int Arch Allergy Immunol 136:5-13. 2005
  13. ncbi Pharmacologic control of asthma
    Sohei Makino
    Dokkyo University School of Medicine
    Int Arch Allergy Immunol 136:14-49. 2005
  14. ncbi Ambroxol inhibits platelet-derived growth factor production in human monocytic cells
    Mitsuyoshi Utsugi
    First Department of Internal Medicine, Gunma University Faculty of Medicine, School of Medicine, 3-39-15 Showa-machi, Gunma, 371-8511, Maebashi, Japan
    Eur J Pharmacol 436:47-51. 2002
    ..These findings indicate that ambroxol inhibits the lipopolysaccharide-induced PDGF production due to the suppression of p44/42 ERK activity...
  15. ncbi Definition, diagnosis, disease types, and classification of asthma
    Sohei Makino
    Dokkyo University School of Medicine
    Int Arch Allergy Immunol 136:3-4. 2005