Research Topics
| Naoki MantaniSummaryAffiliation: Gunma University Country: Japan Publications
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Detail Information
Publications
Herbal medicine and false-positive results on lymphocyte transformation testNaoki Mantani
Department of Japanese Oriental Kampo Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930 0194, Japan
Yakugaku Zasshi 122:399-402. 2002..These examples suggest that LTT for Kampo formulae may be unreliable as a diagnostic method for drug-induced liver injury...
Rhubarb use in patients treated with Kampo medicines--a risk for gastric cancer?Naoki Mantani
Department of Japanese Oriental Kampo Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930 0194, Japan
Yakugaku Zasshi 122:403-5. 2002..Rhubarb use may have little connection with the development of gastric cancer in practice, even if some ingredients in rhubarb have shown carcinogenic activity in experimental studies...
A comparative study between excess-dose users and regular-dose users of rhubarb contained in Kampo medicinesN Mantani
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani
Phytomedicine 9:373-6. 2002....
Challenge tests and kampo medicines: case report and review of the literatureNaoki Mantani
Department of Integrated Japanese Oriental Medicine, Faculty of Medicine, Gunma University School of Medicine, Maebashi, Japan
Am J Chin Med 31:643-8. 2003..The safety and availability of challenge with a small dose of Kampo medicine should be further examined in a larger population with Kampo medicine-induced liver injury...
Lymphocyte transformation test for medicinal herbs yields false-positive results for first-visit patientsNaoki Mantani
Department of Integrated Japanese Oriental Medicine, Gunma University School of Medicine, Maebashi, Japan
Clin Diagn Lab Immunol 10:479-80. 2003..LTTs for both herbs were positive in 12 of 14 patients, suggesting that LTTs for these herbs are unreliable for the diagnosis of Kampo medicine-induced liver injury...
Four cases of panic disorder successfully treated with Kampo (Japanese herbal) medicines: Kami-shoyo-san and Hange-koboku-toNaoki Mantani
Department of Japanese Oriental Kampo Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama, Japan
Psychiatry Clin Neurosci 56:617-20. 2002..These Kampo medicines may be useful as additional or alternative treatments for panic disorder...
A case-control study of purple urine bag syndrome in geriatric wardsNaoki Mantani
Department of Integrated Japanese Oriental Medicine, Faculty of Medicine, Gunma University School of Medicine, 3 39 15 Showa Machi, Maebashi 371 8511, Japan
J Infect Chemother 9:53-7. 2003..These data suggest that a higher bacterial yield in urine acts as the most important factor in PUBS, in combination with other facilitating factors, such as female-specific ones and the alkaline condition of urine...
Macrophage-mediated inhibitory effect of Zingiber officinale Rosc, a traditional oriental herbal medicine, on the growth of influenza A/Aichi/2/68 virusNobuko Imanishi
Department of Oriental Medicine, Toyama Medical and Pharmaceutical University, Toyama 930-0194, Japan
Am J Chin Med 34:157-69. 2006..These data suggested that ZOR itself has no inhibitory effect on the growth of influenza virus, but could exert its effect via macrophage activation leading to production of TNF-alpha...
Natural killer cytolytic activity is associated with the expression of killer cell immunoglobulin-like receptors on peripheral lymphocytes in humanToshiaki Kogure
Department of Integrated Japanese Oriental Medicine, School of Medicine, Gunma University, 3 39 22 Showa machi, Maebashi Gunma 371 8511, Japan
Mediators Inflamm 12:117-21. 2003....
The efficacy of herbal medicine (kampo) in reducing the adverse effects of IFN-beta in chronic hepatitis CMosaburo Kainuma
Department of Japanese Oriental Medicine, Toyama Medical and Pharmaceutical University, Japan
Am J Chin Med 30:355-67. 2002..This study indicates that Kampo medicines are useful for reducing the adverse effects accompanying IFN treatment in patients with chronic hepatitis C without reducing the antiviral effects...
Inducible activity of ginger rhizome (Zingiber offifinale Rosc.) on the mRNA expression of macrophage-inducible nitric oxide (NO) synthase and NO production in a macrophage cell line, RAW264.7 cellsNobuko Imanishi
Department of Oriental Medicine, Toyama Medical and Pharmaceutical University, Sugitani 2630, Toyama 930-0194, Japan
Am J Chin Med 32:727-35. 2004..The activity of ZOR can be considered to contribute, at least in part, to the beneficial effects of ZOR through the macNOS-mediated activation of the biodefense mechanism...
Suppressive effects of Stephania tetrandra on the neutrophil function in patients with rheumatoid arthritisNobuyasu Sekiya
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani 2630, Toyama 930 0194, Japan
Phytother Res 18:247-9. 2004..The findings of this study suggest that the suppressive effect of ST administration on excessive granulocyte activation resulted in the improvement of inflammation with rheumatoid arthritis...
The effect of interleukin-15 on the expression of killer-cell immunoglobulin-like receptors on peripheral natural killer cells in humanToshiaki Kogure
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930 0194, Japan
Mediators Inflamm 11:219-24. 2002..These findings suggest that IL-15 induces the effector functions of resting NK cells throughout the body, and thereby plays a critical role in the activation of tissue-associated immune responses...
Gene expression of cell surface antigens in the early phase of murine influenza pneumonia determined by a cDNA expression array techniqueShinya Sakai
Department of Japanese Oriental Kampo Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930 0194, Japan
Mediators Inflamm 11:359-61. 2002..To study the gene expression pattern induced by influenza virus infection, it is useful to reveal the pathogenesis of influenza virus infection; but this has not been well examined, especially in vivo study...
[Relationships among urine pH, serum uric acid and pyuria in hospitalized elderly patients]Naoki Mantani
Department of Integrated Japanese Oriental Medicine, Faculty of Medicine, Gunma University School of Medicine
Nippon Ronen Igakkai Zasshi 41:542-5. 2004..The relationships among serum uric acid, serum creatinine, urine pH, and pyuria should be examined further in a larger population and in experimental studies...
Reexamination of the relation between menstrual cycle and kampo diagnosis, yin-yangNaoki Mantani
Department of Japanese Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani 2630, Toyama 930-0194, Japan
Am J Chin Med 31:137-40. 2003..Current reexamination of the relationship between yin-yang and menstruation in a larger population is warranted...
Additional inhibitory effect of tea extract on the growth of influenza A and B viruses in MDCK cellsNobuko Imanishi
Department of Oriental Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan
Microbiol Immunol 46:491-4. 2002....
[Opinions of doctors and nurses about appropriate medical treatment for terminally ill geriatric patients]Naoki Mantani
Department of Integrated Japanese Oriental Medicine, Department of General Medicine, Gunma University School of Medicine
Nippon Ronen Igakkai Zasshi 40:504-8. 2003..0544 and 0.0531, respectively). We expect that the present study will activate a discussion of what constitutes appropriate medical treatment for terminally ill geriatric patients...
Modified diagnostic criteria of drug-induced liver injury proposed by the international consensus meetingMotoh Iwasa
Department of Internal Medicine, Division of Gastroenterology and Hepatology Mie University School of Medicine, Tsu, Japan
Hepatogastroenterology 52:869-74. 2005..It remains controversial whether the revised criteria can exclude drugs not causing liver injury...
