Nobukiyo Tanaka

Summary

Affiliation: Graduate School
Country: Japan

Publications

  1. ncbi request reprint Roles of ATP-binding cassette transporter A7 in cholesterol homeostasis and host defense system
    Nobukiyo Tanaka
    Department of Biochemistry, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    J Atheroscler Thromb 18:274-81. 2011
  2. pmc HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7
    Nobukiyo Tanaka
    Biochemistry, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467 8601, Japan
    Atherosclerosis 217:407-14. 2011
  3. doi request reprint Calmodulin interacts with ATP binding cassette transporter A1 to protect from calpain-mediated degradation and upregulates high-density lipoprotein generation
    Noriyuki Iwamoto
    Biochemistry, Nagoya City University Graduate School of Medical Sciences, Nagoya 467 8601, Japan
    Arterioscler Thromb Vasc Biol 30:1446-52. 2010
  4. pmc Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7
    Nobukiyo Tanaka
    Department of Biochemistry, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    J Lipid Res 51:2591-9. 2010
  5. doi request reprint High plasma levels of matrix metalloproteinase-8 in patients with unstable angina
    Yukihiko Momiyama
    Division of Cardiology, National Hospital Organization Tokyo Medical Center, Meguro ku, Tokyo, Japan
    Atherosclerosis 209:206-10. 2010
  6. ncbi request reprint Associations between plasma C-reactive protein levels and the severities of coronary and aortic atherosclerosis
    Yukihiko Momiyama
    Division of Cardiology, National Hospital Organization Tokyo Medical Center, 2 5 1 Higashigaoka, Tokyo, Japan
    J Atheroscler Thromb 17:460-7. 2010
  7. ncbi request reprint Serum resistin levels and cardiovascular events in patients undergoing percutaneous coronary intervention
    Yukihiko Momiyama
    Department of Cardiology, National Hospital Organization Tokyo Medical Center, Meguro ku, Tokyo, Japan
    J Atheroscler Thromb 18:108-14. 2011
  8. ncbi request reprint ATP-binding cassette transporter A1 gene transcription is downregulated by activator protein 2alpha. Doxazosin inhibits activator protein 2alpha and increases high-density lipoprotein biogenesis independent of alpha1-adrenoceptor blockade
    Noriyuki Iwamoto
    Biochemistry Department, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    Circ Res 101:156-65. 2007

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Roles of ATP-binding cassette transporter A7 in cholesterol homeostasis and host defense system
    Nobukiyo Tanaka
    Department of Biochemistry, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    J Atheroscler Thromb 18:274-81. 2011
    ..In this context, HDL apolipoproteins were shown to enhance phagocytosis by stabilizing ABCA7 against calpain-mediated degradation and increasing its activity, shedding light on a new aspect of the regulation of the host-defense system...
  2. pmc HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7
    Nobukiyo Tanaka
    Biochemistry, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467 8601, Japan
    Atherosclerosis 217:407-14. 2011
    ..These findings provide a molecular basis for enhancement of the host-defense system by statins showing that one of their "pleiotropic" effects is in fact achieved through their reaction to a primary target...
  3. doi request reprint Calmodulin interacts with ATP binding cassette transporter A1 to protect from calpain-mediated degradation and upregulates high-density lipoprotein generation
    Noriyuki Iwamoto
    Biochemistry, Nagoya City University Graduate School of Medical Sciences, Nagoya 467 8601, Japan
    Arterioscler Thromb Vasc Biol 30:1446-52. 2010
    ..To investigate the interaction of ATP-binding cassette transporter A1 (ABCA1) with calmodulin in relation to its calpain-mediated degradation because many calpain substrates bind calmodulin to regulate cellular functions...
  4. pmc Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7
    Nobukiyo Tanaka
    Department of Biochemistry, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    J Lipid Res 51:2591-9. 2010
    ..We thus concluded that extracellular helical apolipoproteins augment ABCA7-associated phagocytosis by stabilizing ABCA7. The results demonstrated direct enhancement of the host defense system by HDL components...
  5. doi request reprint High plasma levels of matrix metalloproteinase-8 in patients with unstable angina
    Yukihiko Momiyama
    Division of Cardiology, National Hospital Organization Tokyo Medical Center, Meguro ku, Tokyo, Japan
    Atherosclerosis 209:206-10. 2010
    ..Thus, plasma MMP-8 levels were found to be high in patients with UAP, suggesting that MMP-8 levels in UAP may reflect coronary plaque instability and that MMP-8 is a promising biomarker for UAP...
  6. ncbi request reprint Associations between plasma C-reactive protein levels and the severities of coronary and aortic atherosclerosis
    Yukihiko Momiyama
    Division of Cardiology, National Hospital Organization Tokyo Medical Center, 2 5 1 Higashigaoka, Tokyo, Japan
    J Atheroscler Thromb 17:460-7. 2010
    ..Limited correlations between C-reactive protein (CRP) and coronary artery disease (CAD) have been reported. Recently, MRI became a useful tool for non-invasively evaluating atherosclerotic plaques in thoracic and abdominal aortas...
  7. ncbi request reprint Serum resistin levels and cardiovascular events in patients undergoing percutaneous coronary intervention
    Yukihiko Momiyama
    Department of Cardiology, National Hospital Organization Tokyo Medical Center, Meguro ku, Tokyo, Japan
    J Atheroscler Thromb 18:108-14. 2011
    ..Resistin is an adipocytokine that may link inflammation and atherosclerosis.We studied the associations of resistin levels with cardiovascular events and restenosis...
  8. ncbi request reprint ATP-binding cassette transporter A1 gene transcription is downregulated by activator protein 2alpha. Doxazosin inhibits activator protein 2alpha and increases high-density lipoprotein biogenesis independent of alpha1-adrenoceptor blockade
    Noriyuki Iwamoto
    Biochemistry Department, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    Circ Res 101:156-65. 2007
    ..Doxazosin inhibits AP2alpha activity independent of alpha(1)-adrenoceptor blockade and increases the ABCA1 expression and HDL biogenesis. AP2alpha is a potent pharmacological target for the increase of HDL...