Naoto Kuroda

Summary

Affiliation: Graduate School
Country: Japan

Publications

  1. ncbi request reprint Review of renal carcinoma with t(6;11)(p21;q12) with focus on clinical and pathobiological aspects
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Histol Histopathol 28:685-90. 2013
  2. ncbi request reprint Review of renal tumors associated with Birt-Hogg-Dubé syndrome with focus on clinical and pathobiological aspects
    N Kuroda
    Naoto Kuroda Department of Diagnostic Pathology Kochi Red Cross Hospital, Shin honmachi 2 13 51 Kochi City, Kochi 780 8562, Japan tel 81 88 822 1201 fax 81 88 822 1056 e mail
    Pol J Pathol 65:93-9. 2014
  3. ncbi request reprint Review of small cell carcinoma of the kidney with focus on clinical and pathobiological aspects
    N Kuroda
    Naoto Kuroda Department of Diagnostic Pathology Kochi Red Cross Hospital, Shin honmachi 2 13 51 Kochi City, Kochi 780 8562, Japan tel 81 88 822 1201 fax 81 88 822 1056 e mail
    Pol J Pathol 65:15-9. 2014
  4. ncbi request reprint Recent classification of renal epithelial tumors
    Naoto Kuroda
    Department of Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi City, Kochi, 780 8561, Japan
    Med Mol Morphol 47:68-75. 2014
  5. ncbi request reprint Intratumoral peripheral small papillary tufts: a diagnostic clue of renal tumors associated with Birt-Hogg-Dubé syndrome
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan Electronic address
    Ann Diagn Pathol 18:171-6. 2014
  6. ncbi request reprint Review of tubulocystic carcinoma of the kidney with focus on clinical and pathobiological aspects
    N Kuroda
    Naoto Kuroda MD, Department of Diagnostic Pathology, Kochi Red Cross Hospital Shin honmachi 2 13 51, Kochi City, Kochi 780 8562, Japan, tel 81 88 822 1201, fax 81 88 822 1056, E mail
    Pol J Pathol 64:233-7. 2013
  7. ncbi request reprint Recent advances of immunohistochemistry for diagnosis of renal tumors
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Pathol Int 63:381-90. 2013
  8. doi request reprint Chromophobe renal cell carcinoma, oncocytic variant: a proposal of a new variant giving a critical diagnostic pitfall in diagnosing renal oncocytic tumors
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Shin honmachi 2 13 51, Kochi, Japan
    Med Mol Morphol 46:49-55. 2013
  9. ncbi request reprint Review of renal carcinoid tumor with focus on clinical and pathobiological aspects
    N Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Tokyo, Japan
    Histol Histopathol 28:15-21. 2013
  10. ncbi request reprint Review of renal oncocytosis (multiple oncocytic lesions) with focus on clinical and pathobiological aspects
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Histol Histopathol 27:1407-12. 2012

Collaborators

Detail Information

Publications92

  1. ncbi request reprint Review of renal carcinoma with t(6;11)(p21;q12) with focus on clinical and pathobiological aspects
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Histol Histopathol 28:685-90. 2013
    ..As previously reported cases remain limited to date, further examination in a large scale study will be needed in order to elucidate clinical behavior and molecular characteristics...
  2. ncbi request reprint Review of renal tumors associated with Birt-Hogg-Dubé syndrome with focus on clinical and pathobiological aspects
    N Kuroda
    Naoto Kuroda Department of Diagnostic Pathology Kochi Red Cross Hospital, Shin honmachi 2 13 51 Kochi City, Kochi 780 8562, Japan tel 81 88 822 1201 fax 81 88 822 1056 e mail
    Pol J Pathol 65:93-9. 2014
    ..Renal tumors composed of clear cells may behave in an aggressive fashion. However, renal tumors including hybrid oncocytic tumor, chromophobe RCC and oncocytoma behave mostly in an indolent fashion. ..
  3. ncbi request reprint Review of small cell carcinoma of the kidney with focus on clinical and pathobiological aspects
    N Kuroda
    Naoto Kuroda Department of Diagnostic Pathology Kochi Red Cross Hospital, Shin honmachi 2 13 51 Kochi City, Kochi 780 8562, Japan tel 81 88 822 1201 fax 81 88 822 1056 e mail
    Pol J Pathol 65:15-9. 2014
    ..As there are limited genetic data on SmCC of the kidney, a large series studying this will be needed in the future. ..
  4. ncbi request reprint Recent classification of renal epithelial tumors
    Naoto Kuroda
    Department of Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi City, Kochi, 780 8561, Japan
    Med Mol Morphol 47:68-75. 2014
    ..In this article, we briefly review and introduce the clinical, morphological and genetic features of these tumor entities. ..
  5. ncbi request reprint Intratumoral peripheral small papillary tufts: a diagnostic clue of renal tumors associated with Birt-Hogg-Dubé syndrome
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan Electronic address
    Ann Diagn Pathol 18:171-6. 2014
    ..In conclusion, multifocality/bilaterality of renal tumors, discordance of histologic subtypes, and the presence of intratumoral peripheral small papillary tufts may be important clues to identify BHDS-associated renal tumors. ..
  6. ncbi request reprint Review of tubulocystic carcinoma of the kidney with focus on clinical and pathobiological aspects
    N Kuroda
    Naoto Kuroda MD, Department of Diagnostic Pathology, Kochi Red Cross Hospital Shin honmachi 2 13 51, Kochi City, Kochi 780 8562, Japan, tel 81 88 822 1201, fax 81 88 822 1056, E mail
    Pol J Pathol 64:233-7. 2013
    ..We strongly feel that there is enough clinicopathological evidence to corroborate TCK as a separate entity and that it should be incorporated into the next WHO classification of renal tumors as a separate neoplastic category. ..
  7. ncbi request reprint Recent advances of immunohistochemistry for diagnosis of renal tumors
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Pathol Int 63:381-90. 2013
    ..WT1 and CD57 highlights the diagnosis of metanephric adenoma. The combined panel of PAX2 and PAX8 may be useful in the diagnosis of metastatic RCC...
  8. doi request reprint Chromophobe renal cell carcinoma, oncocytic variant: a proposal of a new variant giving a critical diagnostic pitfall in diagnosing renal oncocytic tumors
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Shin honmachi 2 13 51, Kochi, Japan
    Med Mol Morphol 46:49-55. 2013
    ....
  9. ncbi request reprint Review of renal carcinoid tumor with focus on clinical and pathobiological aspects
    N Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Tokyo, Japan
    Histol Histopathol 28:15-21. 2013
    ..Further investigations are warranted in order to elucidate the critical genetic abnormalities responsible for the pathogenesis of this rare entity in renal neoplastic pathology...
  10. ncbi request reprint Review of renal oncocytosis (multiple oncocytic lesions) with focus on clinical and pathobiological aspects
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Histol Histopathol 27:1407-12. 2012
    ..In one tumor, no germ line mutation of folliculin gene was identified. Published data show that tumors follow a benign course. Further studies will be necessary to clarify the pathogenesis of renal oncocytosis...
  11. doi request reprint High-grade mucinous tubular and spindle cell carcinoma: comparative genomic hybridization study
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Ann Diagn Pathol 15:472-5. 2011
    ..Results of our molecular genetic analysis support the idea that high-grade MTSCC is a real counterpart of low-grade MTSCC. There is no evidence to designate such tumors as unclassified renal cell carcinoma...
  12. doi request reprint Acquired cystic disease-associated renal cell carcinoma with sarcomatoid change and rhabdoid features
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi 780 8562, Japan
    Ann Diagn Pathol 15:462-6. 2011
    ..In conclusion, pathologists and urologists should be aware that rhabdoid features may occur in ACD-associated RCC and that the loss of chromosomes 9 and 14 may occur during the process of sarcomatoid change in ACD-associated RCC...
  13. doi request reprint Combined tubular adenocarcinoma and hepatoid adenocarcinoma arising in Barrett esophagus
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi University, 780 8562 Kochi, Japan
    Ann Diagn Pathol 15:450-3. 2011
    ..Esophageal hepatoid adenocarcinoma seems to be closely associated with Barrett esophagus and show the intestinal phenotype rather than gastric phenotype...
  14. ncbi request reprint Smear cytology findings of large cell neuroendocrine carcinoma of the uterine cervix
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Diagn Cytopathol 41:636-9. 2013
    ..Cytotechnologists or pathologists need to consider a differential diagnosis of LCNEC while examining cervical cytologic specimens; therefore, it is important to correctly identify the cytologic characteristics of this tumor...
  15. ncbi request reprint Multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Histol Histopathol 27:969-74. 2012
    ..To date, there are no reports of metastasis, vascular invasion or sarcomatoid change in MCRCC. Accordingly, nephron sparing surgery is first recommended as a therapeutic strategy...
  16. doi request reprint The majority of triple-negative breast cancer may correspond to basal-like carcinoma, but triple-negative breast cancer is not identical to basal-like carcinoma
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, 780 8562, Japan
    Med Mol Morphol 42:128-31. 2009
    ..The use of combination immunohistochemistry including cytokeratins 5, 14, and 17 and p63 may contribute to the detection of basal-like carcinoma...
  17. ncbi request reprint Adult-onset renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusion with smooth muscle stroma and abnormal vessels
    Naoto Kuroda
    Department of Diagnostic Pathology, Charles University Hospital Plzen, Czech Republic
    Pathol Int 59:486-91. 2009
    ..G-band karyotype was unsuccessful. Pathologists should pay attention to the afore-described unusual stromal reaction of adult-onset RCC associated with Xp11.2 translocations/TFE3 gene fusions...
  18. doi request reprint Clear cell chondrosarcoma: an ultrastructural study
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi 780 8562, Japan
    Med Mol Morphol 42:185-8. 2009
    ....
  19. doi request reprint Chronic sclerosing pyelitis with an increased number of IgG4-positive plasma cells
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi 780 8562, Japan
    Med Mol Morphol 42:236-8. 2009
    ..Finally, pathologists and clinicians should be aware of the possibility that the renal pelvis may be involved in IgG4-related systemic disease...
  20. doi request reprint Hybrid peripheral nerve sheath tumor of the nasal cavity showing schwannomatous, neurofibromatous, and perineuriomatous areas
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, 780 8562, Japan
    Med Mol Morphol 43:82-5. 2010
    ..In conclusion, this is the first case of hybrid PNST reported to occur in the nasopharyngeal area. Pathologists should be aware of the possibility that hybrid PNST may present outside soft tissue...
  21. doi request reprint Ureteral small cell carcinoma
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, 780 8562, Japan
    Med Mol Morphol 42:55-7. 2009
    ..In conclusion, we suggest that endocrine cells in the ureteral urothelial epithelium may be precursor cells of ureteral small cell carcinoma...
  22. doi request reprint Coexistent adenomyoepithelioma and invasive ductal carcinoma of the breast: presentation as separate tumors
    Naoto Kuroda
    Departments of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, 780 8562, Japan
    Med Mol Morphol 41:238-42. 2008
    ..Additionally, our preliminary report suggests that the stromal response of adenomyoepithelioma may resemble that of intraductal papilloma...
  23. doi request reprint Chromophobe renal cell carcinoma: useful diagnostic application of imprint cytology and fluorescence in situ hybridization of chromosomes 10 and 21 in two cases of typical and eosinophilic variants
    Naoto Kuroda
    Departments of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, 780 8562, Japan
    Med Mol Morphol 41:227-32. 2008
    ..In conclusion, we suggest that the combination study of imprint cytology and FISH of chromosomes 10 and 21 as well as routine histology may contribute to the accurate diagnosis of chromophobe RCC...
  24. doi request reprint Elastofibroma: a histochemical, immunohistochemical, and ultrastructural study of two patients
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi 780 8562, Japan
    Med Mol Morphol 41:179-82. 2008
    ....
  25. ncbi request reprint Sarcomatoid acquired cystic disease-associated renal cell carcinoma
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi University, Japan
    Histol Histopathol 23:1327-31. 2008
    ..This is the sixth case of sarcomatoid RCC arising in end-stage kidney disease...
  26. doi request reprint Basal-like carcinoma of the breast: further evidence of the possibility that most metaplastic carcinomas may be actually basal-like carcinomas
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, Japan
    Med Mol Morphol 41:117-20. 2008
    ..Our results supply further evidence that most metaplastic carcinomas may be actually be basallike carcinomas...
  27. doi request reprint Significance of D2-40 expression in the diagnosis of gastrointestinal stromal tumor
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, Japan
    Med Mol Morphol 41:109-12. 2008
    ..In conclusion, we suggest that D2-40 may be an available marker of GISTs, but the expression of D2-40 seems to be not associated with the degree of risk of aggressive behavior...
  28. doi request reprint Diagnostic pitfall on the histological spectrum of adult-onset renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, 780 8562, Japan
    Med Mol Morphol 43:86-90. 2010
    ..Moreover, osseous metaplasia as well as psammoma bodies should be added to the histological spectrum of the stromal change in RCC associated with Xp11.2 translocations/TFE3 gene fusions...
  29. doi request reprint Immunohistochemical application of D2-40 as basal cell marker in evaluating atypical small acinar proliferation of initial routine prostatic needle biopsy materials
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi 780 8562, Japan
    Med Mol Morphol 43:165-9. 2010
    ..In conclusion, the combination of immunohistochemistry of P504S, cytokeratin 5, p63, and D2-40 may contribute to the accurate diagnosis of ASAP in the initial prostatic needle biopsy...
  30. doi request reprint Lymphoepithelioma-like carcinoma of the stomach associated with adenosquamous carcinoma
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi 780 8562, Japan
    Med Mol Morphol 43:170-3. 2010
    ..Finally, this is the first case of gastric lymphoepithelioma-like carcinoma associated with adenosquamous carcinoma, and clinicians and pathologists should recognize the presence of such a tumor...
  31. doi request reprint Acquired cystic disease-associated renal cell carcinoma: an immunohistochemical and fluorescence in situ hybridization study
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Shin honmachi, Kochi, Japan
    Med Mol Morphol 44:228-32. 2011
    ..In conclusion, the numerical abnormalities of chromosomes 3 and 16, irrespective of gain or loss, may be characteristic of ACD-associated RCC...
  32. doi request reprint Chromophobe renal cell carcinoma with prominent lymph node metastasis and polysomy of chromosome 21: poorly differentiated form or "presarcomatoid" form?
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi 780 8562, Japan
    Med Mol Morphol 44:168-73. 2011
    ..Fluorescence in situ hybridization showed monosomy of chromosomes 2 and 10 and polysomy of chromosome 21. Finally, we suggest that this tumor may show the poorly differentiated or presarcomatoid form of chromophobe RCC...
  33. pmc Review of juxtaglomerular cell tumor with focus on pathobiological aspect
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Shin honmachi 2 13 51, Kochi City, Kochi 780 8562, Japan
    Diagn Pathol 6:80. 2011
    ..Additionally, pathologists and urologists need to recognize that this neoplasm in most cases pursues a benign course, but aggressive forms may develop in some cases...
  34. doi request reprint Immunohistochemical application of S100A1 in renal oncocytoma, oncocytic papillary renal cell carcinoma, and two variants of chromophobe renal cell carcinoma
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, 780 8562, Japan
    Med Mol Morphol 44:111-5. 2011
    ..Finally, S100A1 immunohistochemistry may be useful in distinguishing renal oncocytoma from chromophobe RCC, but it may be of no use in the differential diagnosis between renal oncocytoma and oncocytic papillary RCC...
  35. doi request reprint Re-evaluation of histological type by immunohistochemical and genetic study of transcription factors (TFE3 and TFEB) of VHL gene mutation-negative clear cell renal cell carcinoma and other special types of renal tumor
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, 780 8562, Japan
    Med Mol Morphol 44:46-51. 2011
    ..Finally, the cutoff value of TFE3 immunohistochemistry should be more than 2+ with a wide range. The translocation-type renal carcinoma seems to be quite rare...
  36. doi request reprint Acquired cystic disease-associated renal cell carcinoma with gain of chromosomes 3, 7, and 16, gain of chromosome X, and loss of chromosome Y
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi 780 8562, Japan
    Med Mol Morphol 43:231-4. 2010
    ..Finally, we suggest that this tumor may show a close relationship between ACD-associated RCC and papillary RCC, but a large-scale study will be needed to clarify the relationship between ACD-associated RCC and papillary RCC...
  37. doi request reprint Hybrid sclerosing adenosis and basal cell hyperplasia of the prostate
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Med Mol Morphol 43:226-30. 2010
    ..Additionally, this case showed that D2-40 is a useful marker of basal cells...
  38. doi request reprint Clear cell renal cell carcinoma with focal renal angiomyoadenomatous tumor-like area
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Ann Diagn Pathol 15:202-6. 2011
    ..Finally, pathologists should pay attention to the presence of clear cell RCC focally resembling RAT...
  39. doi request reprint Clear cell papillary renal cell carcinoma and clear cell renal cell carcinoma arising in acquired cystic disease of the kidney: an immunohistochemical and genetic study
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Ann Diagn Pathol 15:282-5. 2011
    ..Finally, our results provide further evidence that clear cell papillary RCC may be both morphologically and genetically distinct entity from clear cell RCC and papillary RCC...
  40. doi request reprint Familial gastrointestinal stromal tumor with germ line mutation of the juxtamembrane domain of the KIT gene observed in relatively young women
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Japan
    Ann Diagn Pathol 15:358-61. 2011
    ..To correctly diagnose familial GIST, mutual information should be exchanged among clinicians, pathologists, and molecular scientists...
  41. ncbi request reprint Review of acquired cystic disease-associated renal cell carcinoma with focus on pathobiological aspects
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Histol Histopathol 26:1215-8. 2011
    ..In conclusion, ACD-associated RCC may be widely recognized as a distinct entity in the near future because this tumor is morphologically and genetically different from other renal tumor entities that have been previously established...
  42. ncbi request reprint Review of renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions with focus on pathobiological aspect
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Histol Histopathol 27:133-40. 2012
    ..Further research is required to correlate clinical behavior with the expanding genetic spectrum of this tumor, and to establish standard therapy protocols for primary and metastatic lesions...
  43. ncbi request reprint Chromosomal abnormalities of clear cell renal cell carcinoma: frequent gain of chromosome 7
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi 780 8562, Japan
    Pathol Int 60:9-13. 2010
    ..The present study shows that gain of chromosome 7 is not exclusive to papillary RCC, but it can be found in clear cell RCC as well, and this finding may represent a diagnostic pitfall in distinguishing clear cell RCC from papillary RCC...
  44. doi request reprint Renal oncocytoma with and without intravascular extension into the branches of renal vein have the same morphological, immunohistochemical and genetic features
    Ondrej Hes
    Department of Pathology, Charles University Hospital, Pilsen, Czech Republic
    Virchows Arch 452:285-93. 2008
    ....
  45. ncbi request reprint Renal oncocytoma with and without intravascular extension into the branches of renal vein have the same morphological, immunohistochemical, and genetic features
    Ondrej Hes
    Department of Pathology, Charles University Hospital Plzen, Pilsen, Czech Republic
    Virchows Arch 452:193-200. 2008
    ....
  46. ncbi request reprint Increased iron deposition in rat liver fibrosis induced by a high-dose injection of dimethylnitrosamine
    Limei Guo
    Department of Pathology, School of Medicine, Kochi University, Kochi, Japan
    Exp Mol Pathol 81:255-61. 2006
    ..Our data suggest that increased iron deposition may be involved in the initiation and perpetuation of rat liver fibrosis. Iron-laden macrophages may influence HSCs through the action of TGF-beta(1) in DMN-induced liver fibrosis...
  47. ncbi request reprint Vascularization in tissue remodeling after rat hepatic necrosis induced by dimethylnitrosamine
    Yu Lan Jin
    Department of Pathology, Kochi Medical School, Kochi University, Kohasu, Oko cho, Nankoku, Japan
    Med Mol Morphol 39:33-43. 2006
    ..Namely, hepatic sinusoids in DMN-induced necrotic areas may partly be reorganized possibly by vasculogenesis...
  48. ncbi request reprint Carcinoid tumor of the renal pelvis: consideration on the histogenesis
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi City, Japan
    Pathol Int 58:51-4. 2008
    ..Ultrastructurally, neoplastic cells contained dense core granules in the cytoplasm. Urologists and pathologists should recognize that carcinoid tumor may arise from the renal pelvis...
  49. ncbi request reprint Hyaline globule-like structures in undifferentiated sarcoma cells of malignant müllerian mixed tumor of the fallopian tube
    Naoto Kuroda
    Department of Pathology, Kochi Red Cross Hospital, Kochi 780 8562, Japan
    Med Mol Morphol 40:46-9. 2007
    ..Finally, pathologists should keep in mind that undifferentiated sarcoma cells in MMMT of the fallopian tube may contain hyaline globule-like structures in the cytoplasm...
  50. doi request reprint Possible identification of third stromal component in extraadrenal paraganglioma: myofibroblast in fibrous band and capsule
    Naoto Kuroda
    Departments of Diagnostic Pathology, Kochi Red Cross Hospital, Shin honmachi 2 chome 13 51, Kochi City, Kochi 780 8562, Japan
    Med Mol Morphol 41:59-61. 2008
    ..Finally, we identified the third stromal component, namely, myofibroblasts, in the extraadrenal paraganglioma. These myofibroblasts may play a role in the stromal response of host against neoplasm or the regulation of tumor growth...
  51. ncbi request reprint CAM5.2-positive subserosal myofibroblasts in appendicitis
    Tadashi Hamauzu
    Department of Pathology, Program of Bioregulation and Genetics, Kochi Medical School, Kochi University, Kochi, Japan
    Med Mol Morphol 39:209-13. 2006
    ..Finally, many myofibroblasts appearing in the subserosal area of the perforation of appendicitis may be derived from submesothelial cells or mesothelial cells...
  52. doi request reprint A renal epithelioid angiomyolipoma/perivascular epithelioid cell tumor with TFE3 gene break visualized by FISH
    Chisato Ohe
    Department of Pathology, Kansai Medical University, Hirakata Hospital, 2 3 1 Shinmachi, Hirakata, Osaka 573 1191, Japan
    Med Mol Morphol 45:234-7. 2012
    ..Pathologists should recognize that PEComa with TFE3 gene fusion can arise even in the kidney...
  53. ncbi request reprint Anaplastic carcinoma of the pancreas with rhabdoid features and hyaline globule-like structures
    Naoto Kuroda
    Department of Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi City, Kochi 780 8562, Japan
    Med Mol Morphol 40:168-71. 2007
    ..Ultrastructurally, hyaline globule-like structures corresponded to lysosomes. Finally, we report here the first case of anaplastic carcinoma of the pancreas with hyaline globule-like structures...
  54. ncbi request reprint Renal hybrid oncocytic/chromophobe tumors - a review
    Ondrej Hes
    Department of Pathology, Charles University in Prague, Faculty of Medicine in Plzen, Czech Republic
    Histol Histopathol 28:1257-64. 2013
    ..HOCT (all three clinicopathologic groups) seem to behave indolently, as no evidence of aggressive behavior has been documented. However, no report with follow up longer than 10 years has been published. ..
  55. ncbi request reprint Distribution of myofibroblastic cells in the liver and kidney of Meckel-Gruber syndrome
    Naoto Kuroda
    Department of Pathology, Kochi Medical School, Kochi, Japan
    Pathol Int 54:57-62. 2004
    ..In conclusion, myofibroblastic cells were distributed in the liver and kidney of a patient with MGS and their specific distribution in the liver may be indicative of prestage hepatic fibrosis...
  56. ncbi request reprint Anal canal adenocarcinoma with MUC5AC expression suggestive of anal gland origin
    Naoto Kuroda
    Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, Kochi 780 8562, Japan
    Med Mol Morphol 40:50-3. 2007
    ..Finally, our preliminary report suggests that the immunohistochemical combination of CK7, CK19, and MUC5AC may be an available marker for adenocarcinoma of anal ducts/glands origin...
  57. ncbi request reprint Invasive micropapillary carcinoma of the breast: an immunohistochemical study of neoplastic and stromal cells
    Naoto Kuroda
    Department of Pathology, Kochi Medical School, Kochi, Japan
    Int J Surg Pathol 13:51-5. 2005
    ..Similar results for stromal cells were obtained in all cases. Our results from this preliminary investigation suggest that CD34-positive stromal cells may disappear from the stroma of IMC as well as IDC...
  58. ncbi request reprint Low-grade tubular-mucinous renal neoplasm with neuroendocrine differentiation: a histological, immunohistochemical and ultrastructural study
    Naoto Kuroda
    Department of Pathology, Kochi Medical School, Kochi, Japan
    Pathol Int 54:201-7. 2004
    ..Our results render further evidence that LGTMRN is a distinct entity from the hitherto established renal neoplasms. Foci of clear cells and neuroendocrine differentiation should be added to the histological spectrum of LGTMRN...
  59. ncbi request reprint Invasive micropapillary carcinoma of the urinary bladder: an immunohistochemical study of neoplastic and stromal cells
    Naoto Kuroda
    Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Japan
    Int J Urol 13:1015-8. 2006
    ....
  60. ncbi request reprint Distribution and role of myofibroblasts in human normal seminal vesicle stroma
    Nobuyuki Shimasaki
    Department of Urology, Program of Tumor Biology and Regulation, Kochi Medical School, Kochi University, Kohasu, Oko cho, Nangoku, Kochi, Japan
    Med Mol Morphol 40:208-11. 2007
    ..Finally, myofibroblasts are distributed in the lamina propria of human normal seminal vesicles and may play an important role in the ejection of sperm plasm...
  61. ncbi request reprint Vimentin reactivity in renal oncocytoma: immunohistochemical study of 234 cases
    Ondrej Hes
    Department of Pathology, Charles University Hospital, Pilsen, Czech Republic
    Arch Pathol Lab Med 131:1782-8. 2007
    ..Using different staining and analysis methods, we studied vimentin immunoreactivity in a large series of renal oncocytomas with a special emphasis on the immunoreactivity patterns...
  62. ncbi request reprint Sertoli cell tumor of the testis (not otherwise specified) with the expression of neuroendocrine markers and without the expression of inhibin-alpha
    Naoto Kuroda
    Department of Pathology, Kochi Medical School, Kochi, Japan
    Pathol Int 54:719-24. 2004
    ..It is important to differentiate between Sertoli cell tumor and carcinoid tumor because of the positive reaction for neuroendocrine markers in both tumors. Myofibroblasts are a major stromal component of Sertoli cell tumor of the testis...
  63. ncbi request reprint Invasive micropapillary carcinoma of the colon: an immunohistochemical study
    Naoto Kuroda
    Departments of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi City, Kochi, Japan
    Med Mol Morphol 40:226-30. 2007
    ..Additionally, micropapillary carcinoma of the colon may cause a similar stromal reaction to conventional adenocarcinoma of the colon...
  64. ncbi request reprint Large cell neuroendocrine carcinoma of the lung with calcification and expression of osteopontin
    Naoto Kuroda
    Departments of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi City, Kochi, Japan
    Med Mol Morphol 40:218-20. 2007
    ..Immunohistochemically, parts of neoplastic cells of LCNEC and calcified foci were positive for osteopontin. Finally, we suggest that osteopontin as well as dystrophy within the tumor may be involved in the stromal calcification of LCNEC...
  65. ncbi request reprint Myofibroblasts in the stroma of metastatic pulmonary calcification in a patient with chronic renal failure
    Naoto Kuroda
    Department of Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi 780 8562, Japan
    Med Mol Morphol 39:161-3. 2006
    ....
  66. ncbi request reprint Askin tumor with metastasis to the scalp: a histochemical, immunohistochemical and ultrastructural study
    Naoto Kuroda
    Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi City, Kochi, 780 8562, Japan
    Med Mol Morphol 39:221-5. 2006
    ..Even if results are immunohistochemically negative for neuroendocrine markers, the combination of immunohistochemistry of CD99 (MIC2) and Fil-1 may be useful in diagnosing Askin tumor or its metastatic lesion...
  67. doi request reprint Application of immunocytochemistry to the diagnosis of primary epithelioid angiosarcoma of the lung
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi 780 8562, Japan
    Med Mol Morphol 42:250-3. 2009
    ..Finally, we suggest that the immunocytochemical study of imprint cytological materials may supply available information in diagnosing angiosarcoma with epithelioid features lacking characteristic structures...
  68. doi request reprint Solid papillary carcinoma of the breast: imprint cytological and histological findings
    Naoto Kuroda
    Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2 13 51 Shin honmachi, Kochi, 780 8562, Japan
    Med Mol Morphol 43:48-52. 2010
    ..Nuclear atypia generally showed low grade. Finally, clinicians, cytotechnologists, and pathologists should recognize this rare tumor entity because this tumor is a malignant neoplasm showing characteristic pathological findings...
  69. ncbi request reprint Adenoid basal carcinoma arising in the cervical polyp: an immunohistochemical study of stromal cells
    Naoto Kuroda
    Department of Pathology, Kochi Red Cross Hospital, Kochi, Japan
    Med Mol Morphol 40:112-4. 2007
    ..Gynecologists and pathologists should bear in mind that adenoid basal carcinoma may arise in a cervical polyp...
  70. ncbi request reprint Mixed testicular germ cell tumor in an adult with cryptorchidism and Down's syndrome
    Naoto Kuroda
    Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Kochi City, Kochi, Japan
    APMIS 115:1292-5. 2007
    ..To our knowledge this is the first case of mixed germ cell tumor arising in a patient with Down's syndrome and cryptorchidism...
  71. ncbi request reprint Invasive ductal carcinoma of the breast with signet-ring cell and mucinous carcinoma components: diagnostic utility of immunocytochemistry of signet-ring cells in aspiration cytology materials
    Naoto Kuroda
    Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Kochi, Japan
    Diagn Cytopathol 35:171-3. 2007
    ..Finally, our preliminary report suggests that immunocytochemical examination of aspiration cytology materials may provide useful information in searching the primary site of breast carcinoma with signet-ring cells...
  72. ncbi request reprint Anal canal neuroendocrine carcinoma with Pagetoid extension
    Limei Guo
    Department of Pathology, Program of Bioregulation and Genetics, Kochi Medical School, Kochi, Japan
    Pathol Int 54:630-5. 2004
    ..To the best of our knowledge, this is the first case of anal canal neuroendocrine carcinoma with Pagetoid extension into the overlying epithelium of the histological anal canal...
  73. ncbi request reprint Granular cell tumor arising metachronously in the bronchus and esophagus
    Naoto Kuroda
    Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Shinhonmachi 2 chome 13 51, Kochi City, Kochi 780 8562, Japan
    APMIS 114:659-62. 2006
    ..I believe that this is the first case of GCT occurring metachronously in the respiratory and digestive tracts. Clinicians and pathologists should bear in mind that GCT may arise metachronously in the respiratory and digestive tracts...
  74. ncbi request reprint Malignant müllerian mixed tumor (carcinosarcoma) of the fallopian tube: an immunohistochemical study of neoplastic cells
    Naoto Kuroda
    Department of Pathology, Kochi Medical School, Kochi University, Kochi, Japan
    APMIS 113:643-6. 2005
    ..Finally, our preliminary report suggests that MMMT of the fallopian tube may contain immature smooth muscle cells or cells with the myofibroblast-like immunohistochemical phenotype in the undifferentiated component...
  75. ncbi request reprint Combined small cell carcinoma and sarcomatoid squamous cell carcinoma in the renal pelvis
    Nobuyuki Shimasaki
    Department of Urology and Pathology I, Kochi Medical School, Kochi, Japan
    Int J Urol 12:686-9. 2005
    ..Small cell carcinoma or sarcomatoid squamous cell carcinoma of the renal pelvis is very rare. We believe this is the first such case to be reported in the world...
  76. ncbi request reprint Lipomatous pseudohypertrophy of the pancreas: further evidence of advanced hepatic lesion as the pathogenesis
    Naoto Kuroda
    First Department of Pathology, Kochi Medical School, Chikamori Hospital, Kochi, Japan
    Pathol Int 53:98-101. 2003
    ..Although the pathogenesis of lipomatous pseudohypertrophy of the pancreas is not clear, the findings in the present case provide further evidence to support the hypothesis that advanced hepatic lesions cause this lesion...
  77. ncbi request reprint Intracytoplasmic lumina in invasive micropapillary carcinoma of the lung
    Naoto Kuroda
    Department of Pathology and Clinical Laboratory, Kochi Red Cross Hospital, Kochi, Japan
    Diagn Cytopathol 34:224-6. 2006
    ..Additionally, intracytoplasmic lumina were observed in some neoplastic cells. Finally, carcinoma cells with micropapillary morphology may possess the intracytoplasmic lumina in the cytoplasm of metastatic site as well as primary site...
  78. ncbi request reprint Tissue remodeling following submassive hemorrhagic necrosis in rat livers induced by an intraperitoneal injection of dimethylnitrosamine
    Yu Lan Jin
    First Department of Pathology, Kochi Medical School, Kohasu, Oko cho, Nankoku City, Kochi, 783 8505, Japan
    Virchows Arch 442:39-47. 2003
    ....
  79. ncbi request reprint Fungal effusions associated with invasive pulmonary aspergillosis
    Isao Miyoshi
    Department of Medicine, Kochi University School of Medicine, Kochi, Japan
    Intern Med 45:1019-20. 2006
  80. ncbi request reprint Renal tuberculosis (mortar kidney)
    Miyoshi Isao
    Department of Medicine, Kochi University School of Medicine, Kochi
    Intern Med 45:111-2. 2006
  81. ncbi request reprint Collecting duct carcinoma exhibiting diastase-resistant PAS-positive globular cytoplasmic inclusions and rhabdoid features arising in adult polycystic kidney disease: a case report
    Naoto Kuroda
    Department of Pathology, Kochi Medical School, Japan
    Int J Surg Pathol 12:171-7. 2004
    ..Immunohistochemically, large esosinophilic inclusions were reactive for vimentin. Although these findings are rare in CDCs, they should be recognized in the pathologic spectrum of CDCs. Int J Surg Pathol 12(2):171-177, 2004..
  82. ncbi request reprint Pulmonary squamous cell carcinoma with foci of adenocarcinoma containing micropapillary carcinoma in the metastatic lesion of regional lymph nodes
    Naoto Kuroda
    Pathol Int 57:299-301. 2007
  83. ncbi request reprint ARPP protein is selectively expressed in renal oncocytoma, but rarely in renal cell carcinomas
    Kohei Shomori
    Division of Organ Pathology, Department of Microbiology and Pathology, Tottori University, Yonago, Tottori, Japan
    Mod Pathol 20:199-207. 2007
    ....
  84. ncbi request reprint Collecting duct carcinoma of the kidney
    Naoto Kuroda
    Int J Urol 9:715; author reply 716. 2002
  85. ncbi request reprint Deletion of chromosome 3p14.2-p25 involving the VHL and FHIT genes in conventional renal cell carcinoma
    Farkas Sukosd
    Laboratory of Molecular Oncology, Department of Urology, Ruprecht Karls University, D 69120 Heidelberg, Germany
    Cancer Res 63:455-7. 2003
    ..Our data indicate that LOH at chromosome 3p14.2-p25 is specific for conventional RCC and that loss of one allele of both the VHL and FHIT genes occurs in early stage of tumorigenesis...
  86. doi request reprint Chromophobe renal cell carcinoma and 'capsulomas' with acquired cystic disease of the kidney in a long-term hemodialysis patient
    Keisuke Nishihara
    Division of Organ Pathology, Department of Microbiology and Pathology, Faculty of Medicine, Tottori University, Yonago, Japan
    Int J Urol 15:543-5. 2008
    ..Capsulomas' were multiple subcapsular nodules composed almost entirely of smooth muscle-like cells with immunoreactivity for melanosome-associated antigen detected by HMB-45...
  87. ncbi request reprint Prostatic adenocarcinoma with Paneth cell-like change
    Naoto Kuroda
    APMIS 115:857-8. 2007
  88. ncbi request reprint Mantle cell lymphoma with triple-fusion signals of immunoglobulin heavy chain locus/cyclin D1 gene by fluorescence in situ hybridization
    Naoto Kuroda
    Pathol Int 56:478-9. 2006
  89. ncbi request reprint Low-grade renal epithelial tumor originating from the distal nephron
    Naoto Kuroda
    Int J Urol 11:1153; author reply 1154. 2004
  90. ncbi request reprint Miliary tuberculosis not affecting the lungs but complicated by acute respiratory distress syndrome
    Isao Miyoshi
    Department of Hematology and Respiratory Medicine, Kochi University School of Medicine
    Intern Med 44:622-4. 2005
    ..It should be noted that on rare occasions the lungs may not be involved by miliary tuberculosis...
  91. ncbi request reprint Participation of alpha-smooth muscle actin-positive cells in renomedullary interstitial cell tumors
    Naoto Kuroda
    First Department of Pathology, Kochi Medical School, Kohasu, Oko cho, Nankoku City, Kochi 783 8505, Japan
    Oncol Rep 9:745-50. 2002
    ..Furthermore, TGF-beta 1 may contribute to the formation of fibrosis in the tumors...
  92. ncbi request reprint Renal oncocytomatosis in a long-term hemodialysis patient treated by laparoscopic surgery
    Naoto Kuroda
    Int J Urol 10:510. 2003