Research Topics
| N KurodaSummaryAffiliation: Graduate School Country: Japan Publications
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Detail Information
Publications
Mucinous tubular and spindle cell carcinoma with Fuhrman nuclear grade 3: a histological, immunohistochemical, ultrastructural and FISH studyN Kuroda
Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
Histol Histopathol 23:1517-23. 2008..FISH analysis may be helpful in establishing the diagnosis of this entity. Furthermore, we present the first report of a patient with MTSCC dying of distant metastasis...
The complementary role of beta-catenin in diagnosing various subtypes of renal cell carcinomas and its up-regulation in conventional renal cell carcinomas with high nuclear gradesL Guo
First Department of Pathology, Kochi Medical School, Kochi, Japan
Oncol Rep 8:521-6. 2001..In conventional RCCs with low nuclear grades, beta-catenin expression is generally down-regulated, while it appears to be preserved in those with high nuclear grades...
Distribution and role of CD34-positive stromal cells and myofibroblasts in human normal testicular stromaN Kuroda
Department of Pathology, Program of Bioregulation and Genetics, Kochi Medical School, Kochi, Japan
Histol Histopathol 19:743-51. 2004..This distribution and cytological identification was also confirmed by an ultrastructural study of four cases. Finally, CD34-positive stromal cells and myofibroblasts are major components of human testicular stroma...
Adult-onset herpes simplex virus hepatitis with diffuse myofibroblastic transformation of hepatic stellate cells (Ito cells) in non-necrotic areasM Toi
First Department of Pathology, Kochi Medical School, Kochi, Japan
Pathol Int 51:288-92. 2001..These findings indicate that not only liver cells but also HSC can become necrotic in HSV hepatitis. In contrast, in non-necrotic areas, almost all of the HSC showed active transformation to myofibroblasts...
Expression of CD9/motility-related protein 1 (MRP-1) in renal parenchymal neoplasms: consistent expression in papillary and chromophobe renal cell carcinomasN Kuroda
First Department of Pathology, Kochi Medical School, Kochi, Japan
Hum Pathol 32:1071-7. 2001..These results suggest that CD9 may be a beneficial marker in the differential diagnosis between papillary RCCs and collecting duct carcinomas and also between chromophobe and conventional RCCs...
The distribution of myofibroblasts and CD34-positive stromal cells in normal renal pelvis and ureter and their cancersN Kuroda
Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Kochi City, Kochi, Japan
Histol Histopathol 21:1303-7. 2006..These findings suggest that the invasion of renal pelvic and ureteral cancers may cause the phenotypic change of stromal cells...
Cytokeratin-positive subserosal myofibroblasts in gastroduodenal ulcer; another type of myofibroblastsL Guo
Department of Pathology, Program of Bioregulation and Genetics, Kochi Medical School, Kochi, Japan
Histol Histopathol 21:697-704. 2006..In contrast, in the surface layer of ulceration, stromal cells expressing only ASMA were observed. The cytokeratin-positive subserosal myofibroblastic cell in human gastroduodenal ulcer is a novel type of myofibroblast...
Immunohistochemical identification of intracytoplasmic lumens by cytokeratin typing may differentiate renal oncocytomas from chromophobe renal cell carcinomasN Kuroda
First Department of Pathology, Faculty of Medicine, Kochi University, Kochi, Japan
Histol Histopathol 19:23-8. 2004..Therefore, immunohistochemical identification of ICLs by cytokeratin typing may be useful for differentiating between renal oncocytomas and chromophobe RCCs and be more sensitive in this respect than colloidal iron staining...
Renal leiomyoma: an immunohistochemical, ultrastructural and comparative genomic hybridization studyN Kuroda
Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Kochi, Japan
Histol Histopathol 22:883-8. 2007..Finally, the immunohistochemical panel of smooth muscle markers and ultrastructural and genetic study may be useful in diagnosing renal leiomyoma...
Goblet cell carcinoid of the appendix: Investigation of the expression of beta-catenin and E-cadherinN Kuroda
First Department of Pathology, Kochi Medical School, Kochi, Japan
Pathol Int 51:283-7. 2001..These findings suggest the possibility that, in some cases, the adherens junctions of goblet cell carcinoids are similar to those of typical carcinoids rather than to those of adenocarcinomas...
The disappearance of CD34-positive and alpha-smooth muscle actin-positive stromal cells associated with human intra-uterine and tubal pregnanciesN Kuroda
Department of Pathology, Program of Bioregulation and Genetics, Kochi Medical School, Kochi University, Kochi, Japan
Histol Histopathol 19:707-13. 2004..ASMA-positive stromal cells at the fetal side associated with pregnancy may play a role in the production of villous extracellular matrix or regulation of blood flow...
An immunohistochemical study of developing glomeruli in human fetal kidneysK Naruse
First Department of Pathology and Department of Pediatrics, Kochi Medical School, Kochi, Japan
Kidney Int 57:1836-46. 2000..Our aim was to clarify the characteristics of fetal mesangial cells and glomerular capillary endothelial cells, as well as their changes during glomerulogenesis using immunohistochemistry...
An Asian variant of intravascular lymphoma: unique clinical and pathological manifestation in the gallbladderN Kuroda
Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Kochi, Japan
APMIS 115:371-5. 2007..In conclusion, clinicians and pathologists should keep in mind that the gallbladder may be initially involved in IVL...
The distribution and role of myofibroblasts and CD34-positive stromal cells in normal pancreas and various pancreatic lesionsN Kuroda
Department of Pathology, Kochi Medical School, Kochi, Japan
Histol Histopathol 19:59-67. 2004..Myofibroblasts and CD34-positive stromal cells may play a role in regulating the tumor growth in the capsule of islet cell tumors of the pancreas...
Review of renal oncocytoma with focus on clinical and pathobiological aspectsN Kuroda
First Department of Pathology, Kochi Medical School, Kohasu, Oko cho, Nankoku City, Kochi, Japan
Histol Histopathol 18:935-42. 2003..Therefore, further studies are needed to resolve these problems and also to elucidate the genetic mechanisms responsible for the occurrence of oncocytomas...
Lung adenocarcinoma with a micropapillary pattern: a clinicopathological study of 25 casesN Kuroda
Department of Pathology, Kochi Red Cross Hospital, Kochi, Japan
APMIS 114:381-5. 2006..Lung micropapillary carcinoma of breast type may behave more aggressively than the alveolar type...
Bridging necrosis and reticulin bridging fibrosis induced by intrahepatic involvement of acute biphenotypic leukemiaN Kuroda
Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Kochi City, Kochi, Japan
APMIS 114:908-11. 2006..No cells positive for TGF-beta1 or PDGF-BB were identified. In conclusion, extensive intrahepatic involvement by neoplastic cells in adult acute biphenotypic leukemia may cause the unusual "disorganized" hepatic fibrosis...
Malignant phyllodes tumor of the breast with expression of osteonectin and vinculinN Kuroda
First Department of Pathology, Kochi Medical School, Kochi, Japan
Pathol Int 51:277-82. 2001..Further studies will be necessary to elucidate the significance of vinculin and osteonectin expression in malignant phyllodes tumor...
Review of renal carcinoid tumor with focus on clinical and pathobiological aspectsN Kuroda
Department of Diagnostic Pathology, Kochi Red Cross Hospital, Tokyo, Japan
Histol Histopathol 28:15-21. 2013..Further investigations are warranted in order to elucidate the critical genetic abnormalities responsible for the pathogenesis of this rare entity in renal neoplastic pathology...
Fascin-positive dendritic cells and fibroblastic reticulum cells build a framework of T-cell areas in lymph nodesM Hiroi
The First Department of Pathology, Kochi Medical School, Kohasu, Okoh cho, 783 8505, Nankoku City, Kochi, Japan
Virchows Arch 444:158-63. 2004..In active paracortical response, both FPCs and FRCs are also stimulated and might play a significant role in the maturation of the lymphocytes...
Review of renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions with focus on pathobiological aspectNaoto Kuroda
Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
Histol Histopathol 27:133-40. 2012..Further research is required to correlate clinical behavior with the expanding genetic spectrum of this tumor, and to establish standard therapy protocols for primary and metastatic lesions...
Pulmonary adenocarcinoma with micropapillary component: an immunohistochemical study. Case reportN Kuroda
Department of Pathology, Program of Bioregulation and Genetics, Kochi Medical School, Kochi University, Kohasu, Oko cho, Nankoku City, Kochi, Japan
APMIS 113:550-4. 2005....
Review of renal oncocytosis (multiple oncocytic lesions) with focus on clinical and pathobiological aspectsNaoto Kuroda
Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
Histol Histopathol 27:1407-12. 2012..In one tumor, no germ line mutation of folliculin gene was identified. Published data show that tumors follow a benign course. Further studies will be necessary to clarify the pathogenesis of renal oncocytosis...
Female urethral adenocarcinoma with a heterogeneous phenotypeN Kuroda
Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Kochi, Japan
APMIS 114:314-8. 2006....
Gastric carcinosarcoma with neuroendocrine differentiation as the carcinoma component and leiomyosarcomatous and myofibroblastic differentiation as the sarcomatous componentN Kuroda
Department of Pathology and Laboratory Medicine, Kochi Red Cross Hospital, Kochi, Japan
APMIS 114:234-8. 2006..Pathologists should bear in mind that gastric carcinosarcoma may show various types of differentiation...
Review of sarcomatoid renal cell carcinoma with focus on clinical and pathobiological aspectsN Kuroda
First Department of Pathology, Kochi Medical School, Kohasu, Oko cho, Nankoku City, Kochi, Japan
Histol Histopathol 18:551-5. 2003..Little is know about genetic alterations in sarcomatoid RCCs. Further studies are therefore needed to identify the key gene involved in sarcomatoid transformation of RCCs...
