K Kaira

Summary

Affiliation: Graduate School
Country: Japan

Publications

  1. doi request reprint Prognostic impact of (18)F-FDG uptake on PET in non-small cell lung cancer patients withpostoperative recurrence following platinum-based chemotherapy
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan Electronic address
    Respir Investig 52:121-8. 2014
  2. doi request reprint Biological significance of 18F-FDG uptake on PET in patients with non-small-cell lung cancer
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan Electronic address
    Lung Cancer 83:197-204. 2014
  3. doi request reprint Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    BMC Cancer 13:482. 2013
  4. ncbi request reprint Biological correlation of ¹⁸F-FDG uptake on PET in pulmonary neuroendocrine tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho Sunto gun, Shizuoka, 411 8777, Japan
    Anticancer Res 33:4219-28. 2013
  5. doi request reprint Phase II study of oral S-1 and cisplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan Electronic address
    Lung Cancer 82:449-54. 2013
  6. doi request reprint Phase II study of oral S-1 plus cisplatin with bevacizumab for advanced non-squamous non-small cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan Electronic address
    Lung Cancer 82:103-8. 2013
  7. doi request reprint Clinicopathological significance of L-type amino acid transporter 1 (LAT1) expression in patients with adenoid cystic carcinoma
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma University, Showa machi, Maebashi, Gunma, 371 8511, Japan
    Pathol Oncol Res 19:649-56. 2013
  8. doi request reprint The role of βIII-tubulin in non-small cell lung cancer patients treated by taxane-based chemotherapy
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi cho, Sunto gun, Shizuoka, 411 8777, Japan
    Int J Clin Oncol 18:371-9. 2013
  9. doi request reprint Prognostic and predictive factors in resected non-small-cell lung cancer
    Kyoichi Kaira
    Shizuoka Cancer Center, Division of Thoracic Oncology, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka, 411 8777, Japan 81 55 989 5222 81 55 989 5634
    Expert Opin Med Diagn 4:373-81. 2010
  10. doi request reprint 18F-FDG uptake on PET in primary mediastinal non-thymic neoplasm: a clinicopathological study
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan
    Eur J Radiol 81:2423-9. 2012

Detail Information

Publications105 found, 100 shown here

  1. doi request reprint Prognostic impact of (18)F-FDG uptake on PET in non-small cell lung cancer patients withpostoperative recurrence following platinum-based chemotherapy
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan Electronic address
    Respir Investig 52:121-8. 2014
    ..Only patients with postoperative recurrences who received platinum-based chemotherapy as the initial treatment after recurrence were included in the study...
  2. doi request reprint Biological significance of 18F-FDG uptake on PET in patients with non-small-cell lung cancer
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan Electronic address
    Lung Cancer 83:197-204. 2014
    ..The aim of this study is to investigate the underlying biologic mechanisms of 2-[18F]-fluoro-2-deoxy-d-glucose (18F-FDG) uptake on positron emission tomography (PET) in non-small cell lung cancer (NSCLC)...
  3. doi request reprint Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    BMC Cancer 13:482. 2013
    ..This study was conducted to determine biological significance of LAT1 expression and investigate whether LAT1 could be a prognostic biomarker for biliary tract cancer...
  4. ncbi request reprint Biological correlation of ¹⁸F-FDG uptake on PET in pulmonary neuroendocrine tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho Sunto gun, Shizuoka, 411 8777, Japan
    Anticancer Res 33:4219-28. 2013
    ..We therefore, conducted a study including the analysis of the underlying biology of (18)F-FDG uptake...
  5. doi request reprint Phase II study of oral S-1 and cisplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan Electronic address
    Lung Cancer 82:449-54. 2013
    ..To determine the efficacy and safety of oral S-1 in combination with cisplatin and thoracic radiotherapy in patients with unresectable stage III non-small-cell lung cancer (NSCLC)...
  6. doi request reprint Phase II study of oral S-1 plus cisplatin with bevacizumab for advanced non-squamous non-small cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan Electronic address
    Lung Cancer 82:103-8. 2013
    ..We conducted a phase II study to evaluate the efficacy and safety of S-1 plus cisplatin with bevacizumab followed by maintenance bevacizumab in patients with advanced non-squamous non-small cell lung cancer (NSCLC)...
  7. doi request reprint Clinicopathological significance of L-type amino acid transporter 1 (LAT1) expression in patients with adenoid cystic carcinoma
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma University, Showa machi, Maebashi, Gunma, 371 8511, Japan
    Pathol Oncol Res 19:649-56. 2013
    ..LAT1 is a promising clinical marker to predict the outcome after surgery in patients with ACC...
  8. doi request reprint The role of βIII-tubulin in non-small cell lung cancer patients treated by taxane-based chemotherapy
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi cho, Sunto gun, Shizuoka, 411 8777, Japan
    Int J Clin Oncol 18:371-9. 2013
    ..The aim of this study is to evaluate whether class III β-tubulin (TUBB3) expression could predict progression-free survival or overall survival in relapsed non-small cell lung cancer (NSCLC) patients treated with taxene-based chemotherapy...
  9. doi request reprint Prognostic and predictive factors in resected non-small-cell lung cancer
    Kyoichi Kaira
    Shizuoka Cancer Center, Division of Thoracic Oncology, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka, 411 8777, Japan 81 55 989 5222 81 55 989 5634
    Expert Opin Med Diagn 4:373-81. 2010
    ..Take home message: Search for new prognostic/predictive markers remains an important task for lung cancer diagnosis and treatment...
  10. doi request reprint 18F-FDG uptake on PET in primary mediastinal non-thymic neoplasm: a clinicopathological study
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan
    Eur J Radiol 81:2423-9. 2012
    ..However, little is known about PET imaging of (18)F-FDG in primary non-thymic mediastinal neoplasms. The aim of this study is to explore the clinicopathological significance of (18)F-FDG PET in primary mediastinal (non-thymic) neoplasms...
  11. pmc Prognostic significance of L-type amino-acid transporter 1 expression in surgically resected pancreatic cancer
    K Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Br J Cancer 107:632-8. 2012
    ..However, little is known regarding the clinical significance of LAT1 expression in pancreatic cancer. This study was conducted to determine the prognostic significance of LAT1 expression...
  12. doi request reprint Thymidylate synthase expression is closely associated with outcome in patients with pulmonary adenocarcinoma
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan
    Med Oncol 29:1663-72. 2012
    ..In patients with non-AC, TS expression was not closely correlated with outcome and these biomarkers. A positive TS expression was a powerful prognostic factor to predict a poor outcome in completely resected AC patients...
  13. doi request reprint Depolarized MUC1 expression is closely associated with hypoxic markers and poor outcome in resected non-small cell lung cancer
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan
    Int J Surg Pathol 20:223-32. 2012
    ..Depolarized MUC1 expression was significantly associated with poor outcome. Glucose metabolism, hypoxia, angiogenesis, amino acid metabolism, and EGFR pathway may play an important role in the development of depolarized MUC1 expression...
  14. doi request reprint ¹⁸F-FDG uptake on PET could be a predictive marker of excision repair cross-complementation group 1 (ERCC1) expression in patients with thoracic neoplasms?
    K Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan
    Neoplasma 59:257-63. 2012
    ..Moreover, ERCC1 expression was also closely associated with the expression of Glut1, VEGF and MVD.Our results indicated that 18F-FDG uptake may be an alternative biomarker for predicting ERCC1 expression in patients with thymoma...
  15. doi request reprint Relationship between 18F-FDG uptake on positron emission tomography and molecular biology in malignant pleural mesothelioma
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka, Japan
    Eur J Cancer 48:1244-54. 2012
    ..However, no satisfactory biologic explanation exists for this phenomenon. The aim of this study is to investigate the underlying biologic mechanisms of (18)F-FDG uptake...
  16. doi request reprint MUC1 expression in pulmonary metastatic tumors: a comparison of primary lung cancer
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho Sunto gun, Shizuoka, 411 8777, Japan
    Pathol Oncol Res 18:439-47. 2012
    ..Polarized MUC1 has a different expression pattern between primary and metastatic tumors with adenocarcinoma, and depolarized MUC1 is closely associated with glucose metabolism and hypoxia...
  17. doi request reprint Expression of thymidylate synthase, orotate phosphoribosyltransferase and dihydropyrimidine dehydrogenase in thymic epithelial tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, Sunto gun, Shizuoka, Japan
    Lung Cancer 74:419-25. 2011
    ..Therefore, we investigated the expression of TS, OPRT and DPD in thymic epithelial tumors...
  18. doi request reprint 18F-FMT uptake seen within primary cancer on PET helps predict outcome of non-small cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    J Nucl Med 50:1770-6. 2009
    ..L-[3-(18)F]-alpha-methyl tyrosine ((18)F-FMT) is an amino-acid tracer for PET imaging. We evaluated the prognostic significance of (18)F-FMT PET in patients with non-small cell lung cancer...
  19. doi request reprint A phase II study of amrubicin, a synthetic 9-aminoanthracycline, in patients with previously treated lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Lung Cancer 69:99-104. 2010
    ..This study was designed to confirm the efficacy and safety of amrubicin, a new anthracycline agent, in patients with previously treated non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)...
  20. doi request reprint Phase 2 study of S-1 plus carboplatin in patients with advanced non-small cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Lung Cancer 68:253-7. 2010
    ..The combination of S-1 plus carboplatin is an active and well-tolerated regimen for the treatment of patients with advanced NSCLC. Further investigations are required to confirm our results in randomized trials...
  21. ncbi request reprint L-type amino acid transporter 1 (LAT1) expression in malignant pleural mesothelioma
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan
    Anticancer Res 31:4075-82. 2011
    ..The overexpression of LAT1 was closely associated with poor outcome in patients with MPM. LAT1 is closely associated with tumor development and progression in patients with MPM...
  22. doi request reprint L-type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    J Surg Oncol 99:433-8. 2009
    ..We investigated the significance of LAT1 expression to evaluate malignant potential in thymic epithelial tumors...
  23. doi request reprint CD98 expression is associated with poor prognosis in resected non-small-cell lung cancer with lymph node metastases
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Ann Surg Oncol 16:3473-81. 2009
    ..The purpose of this study was to evaluate the prognostic value of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in resectable non-small-cell lung cancer (NSCLC) patients with N1 and N2 nodal involvement...
  24. doi request reprint Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Lung Cancer 66:120-6. 2009
    ..The purpose of this study was to evaluate the prognostic value of l-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in patients with stage I pulmonary adenocarcinoma...
  25. doi request reprint Correlation of angiogenesis with 18F-FMT and 18F-FDG uptake in non-small cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunman 371 8511, Japan
    Cancer Sci 100:753-8. 2009
    ..The present study demonstrated that the metabolic activity of primary tumors as evaluated by PET study with 18F-FMT and 18F-FDG is related to tumor angiogenesis and the proliferative activity in NSCLC...
  26. doi request reprint Forearm muscle metastasis as an initial clinical manifestation of lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Shouwa machi, Maebashi, Gunma, Japan
    South Med J 102:79-81. 2009
    ..Skeletal muscle metastasis as a mode of presentation of primary lung cancer is an unusual phenomenon...
  27. doi request reprint Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in early stage squamous cell carcinoma of the lung
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Cancer Sci 100:248-54. 2009
    ..A cooperative expression of LAT 1 and CD98 is a significant pathological factor for predicting the poor prognosis in patients with resectable stage I squamous cell carcinoma of the lung...
  28. doi request reprint Evaluation of thoracic tumors with (18)F-FMT and (18)F-FDG PET-CT: a clinicopathological study
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Int J Cancer 124:1152-60. 2009
    ..Our results suggest that coexpression of LAT1 and CD98 in addition to cell proliferation and angiogenesis is relavant for the progression and metastasis of lung cancer...
  29. doi request reprint Laryngeal sarcoidosis detected by FDG positron emission tomography
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan
    Clin Nucl Med 33:878-9. 2008
    ..PET imaging demonstrated increased FDG uptake in the larynx. The histologic examination revealed laryngeal sarcoidosis. We report a case of laryngeal sarcoidosis and emphasize the role of FDG PET...
  30. doi request reprint Pulmonary pleomorphic carcinoma: a clinicopathological study including EGFR mutation analysis
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, Sunto gun, Shizuoka, Japan
    J Thorac Oncol 5:460-5. 2010
    ..Especially, the information on the epidermal growth factor receptor (EGFR) mutation status of pulmonary pleomorphic carcinoma is sparse...
  31. doi request reprint Biologic correlation of 2-[18F]-fluoro-2-deoxy-D-glucose uptake on positron emission tomography in thymic epithelial tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan
    J Clin Oncol 28:3746-53. 2010
    ..However, no satisfactory biologic explanation exists for this phenomenon. The aim of this study was to investigate the underlying biologic mechanisms of [(18)F]FDG uptake...
  32. ncbi request reprint Prognostic significance of thymidylate synthase expression in the adjuvant chemotherapy after resection for pulmonary metastases from colorectal cancer
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho Sunto gun, Shizuoka 411 8777, Japan
    Anticancer Res 31:2763-71. 2011
    ..The aim of this study was to evaluate the prognostic significance of molecular biomarkers including TS expression, after pulmonary metastasectomy followed by 5-fluorouracil-based adjuvant chemotherapy...
  33. doi request reprint Expression of 4F2hc (CD98) in pulmonary neuroendocrine tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan
    Oncol Rep 26:931-7. 2011
    ..Our results suggest that 4F2hc may play a significant role in tumor progression, hypoxic conditions and poor outcome in patients with pulmonary NE tumors...
  34. doi request reprint Correlation between 18F-FDG uptake on PET and molecular biology in metastatic pulmonary tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan
    J Nucl Med 52:705-11. 2011
    ..However, no satisfactory biologic explanation exists for this phenomenon. The aim of this study was to investigate the underlying biologic mechanisms of (18)F-FDG uptake in metastatic pulmonary tumors...
  35. doi request reprint Expression of excision repair cross-complementation group 1, breast cancer susceptibility 1, and β III-tubulin in thymic epithelial tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, Sunto gun, Shizuoka, Japan
    J Thorac Oncol 6:606-13. 2011
    ..We investigated the clinical significance of excision repair cross-complementation group 1 (ERCC1), breast cancer susceptibility 1 (BRCA1), and class III β-tubulin (TUBB3) expression in thymic epithelial tumors...
  36. doi request reprint MUC1 expression in thymic epithelial tumors: MUC1 may be useful marker as differential diagnosis between type B3 thymoma and thymic carcinoma
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka, Japan
    Virchows Arch 458:615-20. 2011
    ..A positive expression of MUC1 was significantly associated with poor outcome in this disease. MUC1 may be useful marker for differentiating thymic carcinoma from type B3 thymoma...
  37. doi request reprint 18F-FDG uptake on PET helps predict outcome and response after treatment in unresectable thymic epithelial tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, Sunto gun, Japan
    Ann Nucl Med 25:247-53. 2011
    ..We evaluated the usefulness of (18)F-FDG PET for monitoring after treatment in unresectable thymic epithelial tumors...
  38. doi request reprint Comparison of L-type amino acid transporter 1 expression and L-[3-18F]-α-methyl tyrosine uptake in outcome of non-small cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Nucl Med Biol 37:911-6. 2010
    ..The purpose of this study is to compare the prognostic significance of (18)F-FAMT uptake in the primary tumors with that of LAT1 expression in patients with NSCLC...
  39. doi request reprint Assessment of therapy response in lung cancer with ¹⁸F-α-methyl tyrosine PET
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Japan
    AJR Am J Roentgenol 195:1204-11. 2010
    ..PET with a novel tracer, L-[3-¹⁸F]-α-methyl tyrosine (¹⁸F-FMT), has been studied in lung cancer. We evaluated ¹⁸F-FMT PET for therapy response in comparison with ¹⁸F-FDG PET...
  40. doi request reprint Ratio of standardized uptake value on PET helps predict response and outcome after chemotherapy in advanced non-small cell lung cancer
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka, 411 8777, Japan
    Ann Nucl Med 24:697-705. 2010
    ..Thus, we evaluated the ratio of SUV(max) of the metastatic tumor to the primary tumor (M/P ratio) to determine whether it could be a useful marker in predicting response and outcome after chemotherapy in advanced NSCLC...
  41. ncbi request reprint CD98 expression is associated with the grade of malignancy in thymic epithelial tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, Sunto gun, Shizuoka 411 8777, Japan
    Oncol Rep 24:861-7. 2010
    ..CD98 expression was associated with the grade of malignancy in thymic epithelial tumors. Moreover, CD98 expression was closely correlated with angiogenesis and cell cycle control, and was useful for predicting poor outcome...
  42. doi request reprint Biologic correlates of ¹⁸F-FDG uptake on PET in pulmonary pleomorphic carcinoma
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka, 411 8777, Japan
    Lung Cancer 71:144-50. 2011
    ..Therefore, we conducted the study including the underlying biologic analysis of ¹⁸F-FDG uptake...
  43. ncbi request reprint Relationship between LAT1 expression and response to platinum-based chemotherapy in non-small cell lung cancer patients with postoperative recurrence
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho Sunto gun, Shizuoka, 411 8777, Japan
    Anticancer Res 31:3775-82. 2011
    ..The aim of this study was to investigate whether L-type amino acid transporter 1 (LAT1) expression can predict poor outcome after chemotherapy in patients with non-small cell lung cancer (NSCLC)...
  44. doi request reprint l-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms
    Kyoichi Kaira
    Deparmtent of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Cancer Sci 99:2380-6. 2008
    ..Moreover, LAT1 expression was significantly correlated with cell proliferation and angiogenesis...
  45. ncbi request reprint Descending necrotizing mediastinitis after upper gastrointestinal endoscopy
    K Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Endoscopy 39:E29. 2007
  46. doi request reprint Primary mediastinal synovial sarcoma: a report of 2 cases
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan
    J Comput Assist Tomogr 32:238-41. 2008
    ..They were treated with radiotherapy and chemotherapy. However, there was complete obstruction of esophagus resulting from progressive diseases. The radiographic findings and treatment were discussed...
  47. ncbi request reprint A phase I dose escalation study of weekly docetaxel and carboplatin in elderly patients with nonsmall cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Am J Clin Oncol 30:51-6. 2007
    ....
  48. ncbi request reprint A phase I dose-escalation study of S-1 plus carboplatin in patients with advanced non-small-cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Japan
    Anticancer Drugs 18:471-6. 2007
    ..Objective responses were seen in four patients (response rate 33%). The combination of S-1 plus carboplatin is a feasible and well-tolerated regimen for the treatment of patients with advanced non-small-cell lung cancer...
  49. ncbi request reprint Small cell carcinoma of the parotid gland
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Otolaryngol Head Neck Surg 136:330-1. 2007
  50. ncbi request reprint Value of FDG positron emission tomography in monitoring the effects of therapy in progressive pulmonary sarcoidosis
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Clin Nucl Med 32:114-6. 2007
  51. ncbi request reprint Fulminant hepatic failure resulting from small-cell lung cancer and dramatic response of chemotherapy
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    World J Gastroenterol 12:2466-8. 2006
    ..Both symptoms remitted following chemotherapy, suggesting swift diagnosis and administration of chemotherapy to be effective in treatment of fulminant hepatic failure and encephalopathy...
  52. ncbi request reprint Diagnostic usefulness of fluorine-18-alpha-methyltyrosine positron emission tomography in combination with 18F-fluorodeoxyglucose in sarcoidosis patients
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Chest 131:1019-27. 2007
    ..This study was conducted to investigate the usefulness of (18)F-FMT PET in combination with fluorine-18-fluorodeoxyglucose ((18)F-FDG) PET for the diagnosis of sarcoidosis in patients with suspected malignancy...
  53. doi request reprint B-cell non-Hodgkin lymphoma presenting as an endobronchial polypoid mass
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Shouwa machi, Maebashi, Gunma, Japan
    J Thorac Oncol 3:530-1. 2008
  54. ncbi request reprint Phase I trial of oral S-1 plus gemcitabine in elderly patients with nonsmall cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Anticancer Drugs 19:289-94. 2008
    ..Objective responses were seen in four patients (response rate, 42.9%). The combination of S-1 plus gemcitabine is a feasible and well-tolerated regimen for the treatment of elderly patients with advanced NSCLC...
  55. doi request reprint Phase I study of oral S-1 plus Cisplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Int J Radiat Oncol Biol Phys 75:109-14. 2009
    ..To determine the maximum tolerated dose (MTD) and recommended dose (RD) of S-1 in combination with cisplatin and thoracic radiotherapy in patients with unresectable Stage III non-small-cell lung cancer (NSCLC)...
  56. ncbi request reprint Rapid growth of malignant pleural mesothelioma
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    J Thorac Oncol 2:966-7. 2007
  57. doi request reprint Pulmonary traumatic pneumatocele and hematoma
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, 371 8511, Japan
    Jpn J Radiol 27:100-2. 2009
    ..Chest imaging revealed multiple pneumatoceles in bilateral lung fields. The patient was treated conservatively without surgical intervention. The pneumatocele had completely disappeared after 4 months...
  58. ncbi request reprint Coinfection of invasive pulmonary aspergillosis and pneumocystis jiroveci pneumonia in a non-HIV patient
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebachi, Gunma 371 8511, Japan
    Acta Med Okayama 61:235-8. 2007
    ..Our case demonstrated that short-term systemic steroid therapy in non-HIV patients with underlying chronic lung conditions and malignancies was a risk factor for IPA and PCP, and for a combination of these infections...
  59. ncbi request reprint Fluorine-18-alpha-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer: a clinicopathologic study
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Clin Cancer Res 13:6369-78. 2007
    ..Tumor uptake of [(18)F]FMT was compared with that of 2-[(18)F]-fluoro-2-deoxy-D-glucose ([(18)F]FDG) and correlated with L-type amino acid transporter 1 (LAT1) expression...
  60. ncbi request reprint Pseudomesotheliomatous adenocarcinoma of the lung with synchronous gastric and esophageal cancer
    K Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Australas Radiol 51:B265-7. 2007
    ..We herein report a very rare case of concomitant pseudomesotheliomatous adenocarcinoma, gastric cancer and esophageal cancer...
  61. doi request reprint Expression of L-type amino acid transporter 1 (LAT1) in neuroendocrine tumors of the lung
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Pathol Res Pract 204:553-61. 2008
    ..The present results suggest that LAT1 may play a significant role in cellular proliferation, lymph node metastasis, and poor outcome in patients with NE tumors of the lung...
  62. pmc Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I-III nonsmall cell lung cancer
    K Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
    Br J Cancer 98:742-8. 2008
    ..There was a significant correlation between LAT1 expression and Ki-67 labelling index. LAT1 expression is a promising pathological factor to predict the prognosis in patients with resectable stage I-III NSCLC...
  63. pmc The role of [¹⁸F]fluorodeoxyglucose positron emission tomography in thymic epithelial tumors
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka, 411 8777, Japan
    Cancer Imaging 11:195-201. 2011
    ..Two papers reported that the degree of [18F]FDG uptake in thymic epithelial tumors is based on glucose metabolism. [18F]FDG-PET may have a further use for radiological differential diagnosis of thymomas and thymic carcinomas...
  64. doi request reprint L-type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non-small cell lung cancer
    Hisao Imai
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan
    Histopathology 54:804-13. 2009
    ..To evaluate the prognostic value of L-type amino acid transporter 1 (LAT1) in patients with stage I non-small cell lung cancer (NSCLC)...
  65. ncbi request reprint Phase II study of weekly docetaxel and cisplatin in patients with non-small cell lung cancer
    Kyoichi Kaira
    Department of Respiratory Medicine, Maebashi Red Cross Hospital, Gunma, Japan
    Anticancer Drugs 16:455-60. 2005
    ..Weekly docetaxel and cisplatin is an effective and safe combination in the treatment of patients with advanced NSCLC...
  66. ncbi request reprint Expectoration of bronchogenic tumour tissue
    K Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Intern Med J 37:340-2. 2007
  67. ncbi request reprint Usefulness of FDG-PET for early prediction of the response to gefitinib in non-small cell lung cancer
    Noriaki Sunaga
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma 371 8511, Japan
    Lung Cancer 59:203-10. 2008
    ..The present preliminary study suggests that FDG-PET may be able to predict response to gefitinib in the early stage of therapy in patients with advanced NSCLC and may have a potential prognostic role...
  68. ncbi request reprint Phase II prospective study of the efficacy of gefitinib for the treatment of stage III/IV non-small cell lung cancer with EGFR mutations, irrespective of previous chemotherapy
    Noriaki Sunaga
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, and Department of Respiratory Medicine, National Nishigunma Hospital, Japan
    Lung Cancer 56:383-9. 2007
    ..The objective of this study was to prospectively evaluate the efficacy of gefitinib in patients with stage III/IV NSCLC whose tumors carried EGFR mutations, irrespective of previous chemotherapy...
  69. doi request reprint Evaluation of the safety and compliance of 3-week cycles of vinorelbine on days 1 and 8 and cisplatin on day 1 as adjuvant chemotherapy in Japanese patients with completely resected pathological stage IB to IIIA non-small cell lung cancer: a retrospective
    Takehito Shukuya
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Nagaizumi, Shizuoka, Japan
    Jpn J Clin Oncol 39:158-62. 2009
    ....
  70. doi request reprint High-grade neuroendocrine carcinoma of the lung shows increased thymidylate synthase expression compared to other histotypes
    Takashi Ibe
    Division of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    J Surg Oncol 102:11-7. 2010
    ..Thymidylate synthase (TS) expression has been reported in various tumors, including non-small-cell lung carcinoma (NSCLC), but not in high-grade neuroendocrine (HGNE) carcinoma of the lung...
  71. ncbi request reprint The relationship between oxidative stress and acid stress in adult patients with mild asthma
    J J Zhao
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan
    J Investig Allergol Clin Immunol 18:41-5. 2008
    ..However, the relationship between these 2 markers and pulmonary function has not been determined in mild asthma patients...
  72. pmc Pulmonary adenocarcinoma presenting as a giant pleural mass
    K Kaira
    Maebashi Red Cross Hospital, Department of Respiratory Medicine, 3 21 36 Asahi cho, Maebashi, Gunma 377 0014, Japan
    Thorax 60:356. 2005
  73. ncbi request reprint A case of primary peritoneal serous papillary carcinoma initially presented by massive bilateral pleural effusions
    K Kaira
    Department of Respiratory Medicine, Maebashi Red Cross Hospital Maebashi, Gunma, Japan
    Eur J Gynaecol Oncol 27:197-9. 2006
    ..Physicians should be aware of a possibility of PSPC when the radiographic findings show massive bilateral pleural effusion due to pleural carcinomatosis, with high serum levels of CA125...
  74. ncbi request reprint Education and imaging. Hepatobiliary and pancreatic: multifocal nodular hepatic steatosis associated with the metabolic syndrome
    T Ichikawa
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    J Gastroenterol Hepatol 22:1693. 2007
  75. pmc Mutation detection of epidermal growth factor receptor and KRAS genes using the smart amplification process version 2 from formalin-fixed, paraffin-embedded lung cancer tissue
    Yohei Miyamae
    Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi 371 8511, Japan
    J Mol Diagn 12:257-64. 2010
    ..This study confirms that the SmartAmp2 assay is suitable for use with DNA extracted from FFPE as well as frozen tissues...
  76. ncbi request reprint Phase I study of biweekly paclitaxel and carboplatin for frail patients with advanced non-small cell lung cancer
    Noriko Yanagitani
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Am J Clin Oncol 30:487-91. 2007
    ....
  77. doi request reprint Pooled analysis of the reports of erlotinib after failure of gefitinib for non-small cell lung cancer
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan
    Lung Cancer 68:99-104. 2010
    ..We sought to compile the available clinical reports to better understand the effectiveness of erlotinib after failure of gefitinib...
  78. doi request reprint Evaluation of S-1 as third- or further-line chemotherapy in advanced non-small-cell lung cancer
    Akira Ono
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi cho, Sunto gun, Shizuoka, 411 8777, Japan
    Int J Clin Oncol 15:161-5. 2010
    ..We conducted a retrospective study to evaluate the efficacy and tolerability of S-1 in patients with failure of second- or further-line chemotherapy...
  79. doi request reprint Efficacy of chemotherapy with carboplatin and paclitaxel for unresectable thymic carcinoma
    Satoshi Igawa
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007, Nagaizumi, Shizuoka 411 8777, Japan
    Lung Cancer 67:194-7. 2010
    ..Thymic carcinoma is a very rarely encountered neoplasm and no optimal chemotherapeutic regimen has been established yet...
  80. ncbi request reprint Epigenetic inactivation of the RAS-effector gene RASSF2 in lung cancers
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma 371 8511, Japan
    Int J Oncol 31:169-73. 2007
    ..Our results indicate that aberrant methylation of the RASSF2 gene with the subsequent loss of RASSF2 expression plays an important role in the pathogenesis of lung cancers...
  81. pmc Usefulness of peptide nucleic acid (PNA)-clamp smart amplification process version 2 (SmartAmp2) for clinical diagnosis of KRAS codon 12 mutations in lung adenocarcinoma: comparison of PNA-clamp SmartAmp2 and PCR-related methods
    Takuya Araki
    Department of Clinical Pharmacology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi 371 8511, Japan
    J Mol Diagn 12:118-24. 2010
    ..In this study, we confirmed that PNA-clamp SmartAmp2 has high sensitivity and accuracy and is suitable for the clinical diagnosis of KRAS codon 12 mutations...
  82. ncbi request reprint Spontaneous expectoration of primary pulmonary synovial sarcoma
    Rieko Watanabe
    Department of Respiratory Medicine, Maebashi Red Cross Hospital, Asahi cho, Maebashi, Gunma, Japan
    J Thorac Oncol 1:1025-6. 2006
  83. ncbi request reprint Intense accumulation of gallium-67 citrate in pancreatic endocrine tumor
    Rieko Watanabe
    Department of Respiratory Medicine, Maebashi Red Cross Hospital, Maebashi, Gunma 371 0014, Japan
    Radiat Med 24:456-8. 2006
    ..No report has described findings of Ga-67 citrate scintigraphy of pancreatic endocrine tumors. Pancreatic endocrine tumor should be included in a differential diagnosis when such scintigraphic findings are encountered...
  84. doi request reprint Oncogenic KRAS-induced epiregulin overexpression contributes to aggressive phenotype and is a promising therapeutic target in non-small-cell lung cancer
    N Sunaga
    Department of Medicine and Molecular Science, Gunma University School of Medicine, Gunma, Japan
    Oncogene 32:4034-42. 2013
    ..Our findings suggest that oncogenic KRAS-induced EREG overexpression contributes to an aggressive phenotype and could be a promising therapeutic target in oncogenic KRAS-driven NSCLC...
  85. doi request reprint Long-term survivors of more than 5 years in advanced non-small cell lung cancer
    Kyoichi Kaira
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Sunto gun, Shizuoka 411 8777, Japan
    Lung Cancer 67:120-3. 2010
    ..The aim of this study is to evaluate the rate of long-term survival of more than 5 years in advanced non-small cell lung cancer (NSCLC)...
  86. doi request reprint Lung cancer producing granulocyte colony-stimulating factor and rapid spreading to peritoneal cavity
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    J Thorac Oncol 3:1054-5. 2008
    ..The final diagnosis obtained at autopsy demonstrated diffuse metastases spreading to peritoneal cavity resulting from G-CSF-producing lung cancer...
  87. doi request reprint Comparison of chemotherapy for unresectable pulmonary high-grade non-small cell neuroendocrine carcinoma and small-cell lung cancer
    Satoshi Igawa
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007, Nagaizumi, Shizuoka 411 8777, Japan
    Lung Cancer 68:438-45. 2010
    ....
  88. ncbi request reprint Gefitinib plus paclitaxel after failure of gefitinib in non-small cell lung cancer initially responding to gefitinib
    Takehito Shukuya
    Division of Thoracic Oncology, Shizuoka Cancer Center, Suntou gun, Shizuoka 411 8777, Japan
    Anticancer Res 29:2747-51. 2009
    ..New therapeutic modalities are needed for non-small cell lung cancer (NSCLC) patients whose tumors have become resistant to gefitinib...
  89. doi request reprint Primary thymic mucosa-associated lymphoid tissue lymphoma: diagnostic tips
    Kimihiro Shimizu
    Division of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    J Thorac Oncol 5:117-21. 2010
    ..Thymic MALT lymphoma needs to be included in the differential diagnosis in Asian patients with a cystic thymic mass accompanied by autoimmune disease or hyperglobulinemia...
  90. ncbi request reprint L-type amino-acid transporter 1 expression predicts the response to preoperative hyperthermo-chemoradiotherapy for advanced rectal cancer
    Takeshi Ebara
    Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Anticancer Res 30:4223-7. 2010
    ..To evaluate whether expression of L-type amino acid transporter 1 (LAT1) in pretreatment rectal cancer biopsies is predictive of tumour response to neoadjuvant hyperthermo-chemoradiotherapy (HCRT)...
  91. ncbi request reprint Serum amylase is a sensitive tumor marker for amylase-producing small cell lung cancer?
    Noriko Yanagitani
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma, 371 8511, Japan
    Int J Clin Oncol 12:231-3. 2007
    ..However, unfortunately, he died owing to deterioration of lung cancer. In this patient, the serum amylase level was found to be a highly sensitive marker of lung cancer...
  92. ncbi request reprint Pulmonary toxicity associated with vinorelbine-based chemotherapy in breast cancer
    Noriko Yanagitani
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
    Gan To Kagaku Ryoho 35:1619-21. 2008
    ..After discontinuing the above vinorelbine therapy, the patient's condition improved. We therefore diagnosed this as a case of vinorelbine-and trastuzumab-induced interstitial pneumonia...
  93. ncbi request reprint [Lung cancer]
    Eriko Ayabe
    Division of Thoracic Oncology, Shizuoka Cancer Center, Japan
    Gan To Kagaku Ryoho 36:21-5. 2009
    ..Novel potential biomarkers for prognostication have been developed by genomic methods. Biomarker development for early detection is much awaited for the future...
  94. doi request reprint Thymic squamous cell carcinoma producing granulocyte colony-stimulating factor associated with a high serum level of interleukin 6
    Eriko Ayabe
    Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo Nagaizumi cho, Shizuoka 411 8777, Japan
    Int J Clin Oncol 14:534-6. 2009
    ..He was treated with thoracic radiotherapy, and chest imaging revealed a marked reduction of tumor size. He was doing well at 8 months after tumor diagnosis...
  95. ncbi request reprint Management of malignant pericardial effusion with instillation of mitomycin C in non-small cell lung cancer
    Kyoichi Kaira
    Maebashi Red Cross Hospital, Department of Respiratory Medicine, 3 21 36, Asahi cho, Maebashi, Gunma 377 0014, Japan
    Jpn J Clin Oncol 35:57-60. 2005
    ....
  96. ncbi request reprint Barium sulphate aspiration
    Kyoichi Kaira
    Department of Respiratory Medicine, Gunma University, Shouwa machi, Maebashi, Gunma 371 8511, Japan
    Lancet 364:2220. 2004
  97. ncbi request reprint Small cell carcinoma of the larynx in a long-term survivor of small-cell lung cancer
    Kyoichi Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    J Clin Oncol 24:2961-3. 2006
  98. ncbi request reprint Inhibition of L-type amino acid transporter 1 has antitumor activity in non-small cell lung cancer
    Hisao Imai
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3 39 Showa machi, Maebashi, Gunma 371 8511, Japan
    Anticancer Res 30:4819-28. 2010
    ..L-type amino acid transporter 1 (LAT1) is highly expressed in various human neoplasms. Antitumor activity of inhibiting LAT1 was analyzed in non-small cell lung cancer (NSCLC)...
  99. ncbi request reprint [Thymic cancer effectively treated by combination chemotherapy of carboplatin and etoposide with concurrent radiotherapy]
    Kyoichi Kaira
    Dept of Respiratory Medicine, Maebashi Red Cross Hospital
    Gan To Kagaku Ryoho 32:1989-92. 2005
    ..Finally, the thymic cancer and small pulmonary metastatic lesions were all resected. This concurrent chemoradiotherapy can be effective against inoperable squamous cell carcinoma of the thymus...
  100. ncbi request reprint [A case of multidrug-resistant non-small cell lung cancer responding to TS-1]
    Hisao Imai
    Dept of Medicine and Molecular Science, Gunma University Graduate School of Medicine
    Gan To Kagaku Ryoho 34:221-4. 2007
    ..Chest computed tomography showed a partial response. Hematologic and non-hematologic toxicities were mild with the TS-1 administration. TS-1 could be an effective agent for treatment of multidrug-resistant non-small cell lung cancer...
  101. ncbi request reprint Effective combination chemotherapy of carboplatin and paclitaxel in the treatment of a recurrent small-cell lung cancer patient
    Kyoichi Kaira
    Dept of Medicine and Molecular Science, Gunma University Graduate School of Medicine
    Gan To Kagaku Ryoho 34:225-7. 2007
    ..Our result suggests that weekly chemotherapy with carboplatin and paclitaxel could be a well-tolerated and effective regimen for salvage chemotherapy of recurrent SCLC...