O Gotoh

Summary

Country: Japan

Publications

  1. ncbi A weighting system and algorithm for aligning many phylogenetically related sequences
    O Gotoh
    Department of Biochemistry, Saitama Cancer Center Research Institute, Japan
    Comput Appl Biosci 11:543-51. 1995
  2. ncbi Divergent structures of Caenorhabditis elegans cytochrome P450 genes suggest the frequent loss and gain of introns during the evolution of nematodes
    O Gotoh
    Saitama Cancer Center Research Institute, Saitama, Japan
    Mol Biol Evol 15:1447-59. 1998
  3. ncbi Gene structure and chromosomal location of a human bHLH transcriptional factor DEC1 x Stra13 x SHARP-2/BHLHB2
    M Teramoto
    Department of Biochemistry, Hiroshima University School of Dentistry, Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    J Biochem 129:391-6. 2001
  4. ncbi Structure, evolution, and liver-specific expression of sterol 12alpha-hydroxylase P450 (CYP8B)
    H Ishida
    Department of Biochemistry, Hiroshima University School of Dentistry, Minami Ku, Hiroshima, 734 8553, Japan
    J Biochem 126:19-25. 1999
  5. ncbi Membrane-bound transferrin-like protein (MTf): structure, evolution and selective expression during chondrogenic differentiation of mouse embryonic cells
    K Nakamasu
    Department of Biochemistry, Hiroshima University School of Dentistry, Kasumi 1 2 3, Minami Ku, Hiroshima, Japan
    Biochim Biophys Acta 1447:258-64. 1999
  6. ncbi Structural and phylogenetic analyses of RGD-CAP/beta ig-h3, a fasciclin-like adhesion protein expressed in chick chondrocytes
    T Kawamoto
    Department of Biochemistry, Hiroshima University, School of Dentistry, Japan
    Biochim Biophys Acta 1395:288-92. 1998
  7. ncbi Homology-based gene structure prediction: simplified matching algorithm using a translated codon (tron) and improved accuracy by allowing for long gaps
    O Gotoh
    Saitama Cancer Center Research Institute, 818 Komuro Ina machi, Saitama 362 0806, Japan
    Bioinformatics 16:190-202. 2000
  8. ncbi Structural characterization of the gene encoding rat 25-hydroxyvitamin D3 24-hydroxylase
    Y Ohyama
    Department of Biochemistry, Hiroshima University School of Dentistry, Japan
    Biochemistry 32:76-82. 1993
  9. ncbi Cloning and gene mapping of the mouse homologue of the CBFA2T1 gene associated with human acute myeloid leukemia
    M Niwa-Kawakita
    Laboratory of Experimental Animal Science, Saitama Cancer Center Research Institute, Japan
    Genomics 29:755-9. 1995

Collaborators

Detail Information

Publications9

  1. ncbi A weighting system and algorithm for aligning many phylogenetically related sequences
    O Gotoh
    Department of Biochemistry, Saitama Cancer Center Research Institute, Japan
    Comput Appl Biosci 11:543-51. 1995
    ..Consistency of nearly 90% was attained between structural and sequence alignments of multiple divergent globins, confirming the effectiveness of this strategy in improving the quality of multiple sequence alignment...
  2. ncbi Divergent structures of Caenorhabditis elegans cytochrome P450 genes suggest the frequent loss and gain of introns during the evolution of nematodes
    O Gotoh
    Saitama Cancer Center Research Institute, Saitama, Japan
    Mol Biol Evol 15:1447-59. 1998
    ..All of these findings are explained better by the intron-late view than by the intron-early view...
  3. ncbi Gene structure and chromosomal location of a human bHLH transcriptional factor DEC1 x Stra13 x SHARP-2/BHLHB2
    M Teramoto
    Department of Biochemistry, Hiroshima University School of Dentistry, Kasumi, Minami Ku, Hiroshima 734 8553, Japan
    J Biochem 129:391-6. 2001
    ..The DEC1 gene locates at Chromosome 3p25.3--26 by the FISH method. This is the first study to determine the genomic structure of the DEC1 gene subgroup...
  4. ncbi Structure, evolution, and liver-specific expression of sterol 12alpha-hydroxylase P450 (CYP8B)
    H Ishida
    Department of Biochemistry, Hiroshima University School of Dentistry, Minami Ku, Hiroshima, 734 8553, Japan
    J Biochem 126:19-25. 1999
    ..The enhanced CYP8B mRNA expression in streptozotocin-induced diabetic rats was significantly decreased by insulin within 3 h of its administration. These facts demonstrate a regulatory role of insulin in CYP8B expression as a suppressor...
  5. ncbi Membrane-bound transferrin-like protein (MTf): structure, evolution and selective expression during chondrogenic differentiation of mouse embryonic cells
    K Nakamasu
    Department of Biochemistry, Hiroshima University School of Dentistry, Kasumi 1 2 3, Minami Ku, Hiroshima, Japan
    Biochim Biophys Acta 1447:258-64. 1999
    ..The structural characteristics and the expression pattern suggest that during development and in adult tissues, MTf has some functions that are different from those of other transferrins...
  6. ncbi Structural and phylogenetic analyses of RGD-CAP/beta ig-h3, a fasciclin-like adhesion protein expressed in chick chondrocytes
    T Kawamoto
    Department of Biochemistry, Hiroshima University, School of Dentistry, Japan
    Biochim Biophys Acta 1395:288-92. 1998
    ..Phylogenetic analysis showed that a portion of the common ancestor gene for RGD-CAP/beta ig-h3 and OSF2 was duplicated to form four repeat domains before the separation of the genes followed by the divergence of vertebrate species...
  7. ncbi Homology-based gene structure prediction: simplified matching algorithm using a translated codon (tron) and improved accuracy by allowing for long gaps
    O Gotoh
    Saitama Cancer Center Research Institute, 818 Komuro Ina machi, Saitama 362 0806, Japan
    Bioinformatics 16:190-202. 2000
    ..Accurate prediction of CDSs may be achieved by directly matching the DNA sequence with a known protein sequence or profile of a homologous family member(s)...
  8. ncbi Structural characterization of the gene encoding rat 25-hydroxyvitamin D3 24-hydroxylase
    Y Ohyama
    Department of Biochemistry, Hiroshima University School of Dentistry, Japan
    Biochemistry 32:76-82. 1993
    ..The structure of the gene is discussed in relation to present knowledge about the mechanism of regulation of the 25-hydroxyvitamin D3 24-hydroxylase and calcium homeostasis...
  9. ncbi Cloning and gene mapping of the mouse homologue of the CBFA2T1 gene associated with human acute myeloid leukemia
    M Niwa-Kawakita
    Laboratory of Experimental Animal Science, Saitama Cancer Center Research Institute, Japan
    Genomics 29:755-9. 1995
    ..The chromosomal location was also confirmed by fluorescence in situ hybridization...