T Yanai

Summary

Affiliation: Gifu University
Country: Japan

Publications

  1. pmc Constitutive phosphorylation of the mTORC2/Akt/4E-BP1 pathway in newly derived canine hemangiosarcoma cell lines
    Atsuko Murai
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu, 501 1193, Japan
    BMC Vet Res 8:128. 2012
  2. doi request reprint Spontaneous T/NK-cell lymphoma associated with simian lymphocryptovirus in a Japanese macaque (Macaca fuscata)
    A Hirata
    Division of Animal Experiment, Life Science Research Center, Japan
    J Comp Pathol 148:43-6. 2013
  3. doi request reprint An ocular infection model using suckling hamsters inoculated with equine herpesvirus 9 (EHV-9): kinetics of the virus and time-course pathogenesis of EHV-9-induced encephalitis via the eyes
    N El-Habashi
    Department of Veterinary Pathology and Microbiology, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    Vet Pathol 50:56-64. 2013
  4. doi request reprint Disseminated mycosis in a killer whale (Orcinus orca)
    Walied Abdo
    Laboratory of Veterinary Pathology, Gifu University, Gifu, Japan
    J Vet Diagn Invest 24:211-8. 2012
  5. pmc Establishment of canine hemangiosarcoma xenograft models expressing endothelial growth factors, their receptors, and angiogenesis-associated homeobox genes
    Atsushi Kodama
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Gifu University, Gifu, Japan
    BMC Cancer 9:363. 2009
  6. doi request reprint Immunohistochemical demonstration of angiogenesis-associated homeobox proteins in canine vascular tumours
    A Kodama
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 141:199-203. 2009
  7. doi request reprint Kinetics and pathogenicity of oral infection by equine herpesvirus-9 in mice and suckling hamsters
    E El-Nahass
    Department of Veterinary Pathology, Faculty of Applied Biological Science, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 146:211-22. 2012
  8. doi request reprint Kinetics and pathogenicity of equine herpesvirus-9 infection following intraperitoneal inoculation in hamsters
    E El-Nahass
    Department of Veterinary Pathology, Faculty of Applied Biological Science, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 145:271-81. 2011
  9. doi request reprint Study on the infectivity of equine herpesvirus 9 (EHV-9) by different routes of inoculation in hamsters
    N El-Habashi
    Department of Veterinary Pathology and Microbiology, Gifu University, Gifu 501 1193 Japan
    Vet Pathol 48:558-64. 2011
  10. doi request reprint Orbital embryonal rhabdomyosarcoma with metastasis in a young dog
    Y Kato
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 147:191-4. 2012

Collaborators

Detail Information

Publications25

  1. pmc Constitutive phosphorylation of the mTORC2/Akt/4E-BP1 pathway in newly derived canine hemangiosarcoma cell lines
    Atsuko Murai
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu, 501 1193, Japan
    BMC Vet Res 8:128. 2012
    ..Here, we characterized new canine HSA cell lines derived from nude mice-xenografted canine HSAs and investigated the deregulation of the signaling pathways in these cell lines...
  2. doi request reprint Spontaneous T/NK-cell lymphoma associated with simian lymphocryptovirus in a Japanese macaque (Macaca fuscata)
    A Hirata
    Division of Animal Experiment, Life Science Research Center, Japan
    J Comp Pathol 148:43-6. 2013
    ..This is the first report of simian LCV-associated T/NK-cell lymphoma with the predominant expression of T-cell antigens in non-human primates...
  3. doi request reprint An ocular infection model using suckling hamsters inoculated with equine herpesvirus 9 (EHV-9): kinetics of the virus and time-course pathogenesis of EHV-9-induced encephalitis via the eyes
    N El-Habashi
    Department of Veterinary Pathology and Microbiology, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    Vet Pathol 50:56-64. 2013
    ..This conjunctival EHV-9 suckling hamster model may be useful in assessing the neuronal spread of neuropathogenic viruses via the eyes to the brain...
  4. doi request reprint Disseminated mycosis in a killer whale (Orcinus orca)
    Walied Abdo
    Laboratory of Veterinary Pathology, Gifu University, Gifu, Japan
    J Vet Diagn Invest 24:211-8. 2012
    ..The present case involves dual infection with Mucor and Aspergillus species in a killer whale with concurrent herpesvirus...
  5. pmc Establishment of canine hemangiosarcoma xenograft models expressing endothelial growth factors, their receptors, and angiogenesis-associated homeobox genes
    Atsushi Kodama
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Gifu University, Gifu, Japan
    BMC Cancer 9:363. 2009
    ..In the present study, we established 6 xenograft canine HSA tumors and detected the expression of growth factors, their receptors, and angiogenic homeobox genes...
  6. doi request reprint Immunohistochemical demonstration of angiogenesis-associated homeobox proteins in canine vascular tumours
    A Kodama
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 141:199-203. 2009
    ..Overall, homeobox protein expression in HSA appears to have a phenotype similar to that of active ECs in angiogenesis. The expression of homeobox genes associated with angiogenesis might be associated with the malignant growth of HSA...
  7. doi request reprint Kinetics and pathogenicity of oral infection by equine herpesvirus-9 in mice and suckling hamsters
    E El-Nahass
    Department of Veterinary Pathology, Faculty of Applied Biological Science, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 146:211-22. 2012
    ..These findings show that EHV-9 may spread via the trigeminal nerve when mice and hamsters are inoculated orally with virus...
  8. doi request reprint Kinetics and pathogenicity of equine herpesvirus-9 infection following intraperitoneal inoculation in hamsters
    E El-Nahass
    Department of Veterinary Pathology, Faculty of Applied Biological Science, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 145:271-81. 2011
    ..Examination of other organs also revealed the presence of EHV-9, suggesting that the virus might infect tissues other than those of the nervous system...
  9. doi request reprint Study on the infectivity of equine herpesvirus 9 (EHV-9) by different routes of inoculation in hamsters
    N El-Habashi
    Department of Veterinary Pathology and Microbiology, Gifu University, Gifu 501 1193 Japan
    Vet Pathol 48:558-64. 2011
    ..These results suggest that in the animals infected by the oral, ocular, and peritoneal routes, EHV-9 might travel to the brain through nerves, other than by the olfactory route, after initial propagation at the site of viral entry...
  10. doi request reprint Orbital embryonal rhabdomyosarcoma with metastasis in a young dog
    Y Kato
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 147:191-4. 2012
    ..One month later, multiple masses throughout the body were identified, in particular around the cervical region. One of these lesions was sampled and diagnosed as metastatic ERS. The dog died 84 days after the time of first admission...
  11. ncbi request reprint Experimental infection of equine herpesvirus 9 in dogs
    T Yanai
    Department of Veterinary Pathology and Microbiology, Faculty of Agriculture, Gifu University, Japan
    Vet Pathol 40:263-7. 2003
    ..These findings indicate that dogs are fully susceptible to EHV-9 and that EHV-9 can cause fulminant encephalitis with high mortality in dogs, as in gazelles and goats...
  12. doi request reprint Expression of the anti-apoptotic factors Bcl-2 and survivin in canine vascular tumours
    M Murakami
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 139:1-7. 2008
    ..The discrepancy between bcl-2 mRNA and bcl-2 protein expression requires further investigation, but the results suggest that malignant proliferation in canine HSAs is associated with bcl-2 and survivin expression...
  13. doi request reprint Effects of equine herpesvirus-9 infection in pregnant mice and hamsters
    N El-Habashi
    Department of Veterinary Pathology, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 144:103-12. 2011
    ..These results suggest that EHV-9 can cause the death of the fetus or abortion and that these events may be secondary to placental vascular compromise...
  14. doi request reprint Nasal neuroendocrine carcinoma in a free-living Japanese raccoon dog (Nyctereutes procyonoides viverrinus)
    M Kubo
    United Graduate School of Veterinary Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 140:67-71. 2009
    ..The tumour had infiltrated the cerebrum and metastasized to the pituitary gland, mandibular and pulmonary lymph nodes, lungs, thyroid gland and adrenal glands...
  15. doi request reprint A pathological study of sepsis associated with sarcoptic mange in raccoon dogs (Nyctereutes procyonoides) in Japan
    T L D R Nakagawa
    Division of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 141:177-81. 2009
    ..This infection was therefore very similar to "crusted scabies" or "Norwegian scabies" in man and was characterized by severe pathology and high mortality, with deaths frequently occurring due to sepsis...
  16. doi request reprint Pathological features of Mycobacterium kansasii infection in black bearded sakis (Chiropotes satanas)
    A Murai
    Laboratory of Veterinary Pathology, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 147:566-9. 2012
    ..Mycobacterium kansasii was identified by PCR in the lymph nodes of the animal with disseminated disease. Mycobacterial speciation was not as readily achieved in the animal with cutaneous nodules only...
  17. ncbi request reprint Expression of vascular endothelial growth factor, basic fibroblast growth factor, and their receptors (flt-1, flk-1, and flg-1) in canine vascular tumors
    K Yonemaru
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    Vet Pathol 43:971-80. 2006
    ..These results suggest that the expression of the growth factors and their receptors, especially flk-1, might be associated with the malignant proliferation of HSAs...
  18. ncbi request reprint Detection of canine pemphigus foliaceus autoantigen by immunoblotting
    T Iwasaki
    Veterinary Medical Teaching Hospital, Gifu University, Japan
    Vet Immunol Immunopathol 59:1-10. 1997
    ..These results suggested that the autoantibodies in sera from canine PF recognised the 160 kDa desmosomal proteins, which may correspond to the desmoglein 1...
  19. ncbi request reprint Malignant melanoma of the palpebral conjunctiva in a captive fallow deer
    H Sakai
    Department of Veterinary Pathology, Faculty of Agriculture, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Wildl Dis 37:816-9. 2001
    ..Numerous mitotic figures and lymphatic invasions were observed. This is a very rare case of a malignant melanoma arising from the palpebral conjunctiva in a wild ruminant...
  20. ncbi request reprint Gazelle herpesvirus 1: a new neurotropic herpesvirus immunologically related to equine herpesvirus 1
    H Fukushi
    Faculty of Agriculture, Gifu University, Gifu, 501 11, Japan
    Virology 227:34-44. 1997
    ..We conclude that GHV-1 is a new type of equine herpesvirus with strong neurotropism...
  21. ncbi request reprint Teratoma of the umbilical cord in a giraffe (Giraffa camelopardalis reticulata)
    A Murai
    Department of Veterinary Pathology, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    Vet Pathol 44:204-6. 2007
    ..Based on these findings, the tumor was diagnosed as a teratoma originating from the umbilical cord. This is possibly the second reported case of umbilical cord teratoma in animals...
  22. doi request reprint Genetic characterization of Protostrongylus shiozawai from Japanese serows (Capricornis crispus)
    M Murakami
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Parasitol 97:1178-80. 2011
    ..PCR using genetic markers in the ITS-2 region should provide a useful tool for expanded studies of P. shiozawai and other Protostrongylus species...
  23. ncbi request reprint Lingual calcinosis circumscripta in a captive sitatunga
    T Yanai
    Department of Veterinary Pathology, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Wildl Dis 37:813-5. 2001
    ..The amorphous material was positive for PAS and von Kossa's stain. Calcinosis circumscripta is rare in the Bovidae...
  24. ncbi request reprint Experimental infection with equine herpesvirus 9 (EHV-9) in cats
    T Yanai
    Department of Veterinary Pathology and Microbiology, Faculty of Agriculture, Gifu University, 1 1 Yanagido, Gifu, 501 1193, Japan
    J Comp Pathol 128:113-8. 2003
    ..These findings indicate that the cat, like certain other species such as the goat, is susceptible to experimental infection with EHV-9, and may be at risk from natural infection...
  25. doi request reprint Pulmonary zygomycosis with Cunninghamella bertholletiae in a killer whale (Orcinus orca)
    W Abdo
    Department of Veterinary Pathology, Faculty of Applied Biological Science, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    J Comp Pathol 147:94-9. 2012
    ..Bacteriological culture revealed the presence of Proteus mirabilis, Pseudomonas aeruginosa and Pseudomonas oryzihabitans. This case represents the first documentation of zygomycosis associated with C. bertholletiae in a marine mammal...