T Deguchi

Summary

Affiliation: Gifu University
Country: Japan

Publications

  1. pmc Threat to cefixime treatment for gonorrhea
    Shigeaki Yokoi
    Emerg Infect Dis 13:1275-7. 2007
  2. pmc Alteration in the GyrA subunit of DNA gyrase and the ParC subunit of DNA topoisomerase IV in quinolone-resistant clinical isolates of Staphylococcus epidermidis
    Z Li
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Antimicrob Agents Chemother 42:3293-5. 1998
  3. ncbi request reprint Development of a rapid assay for screening point mutations associated with quinolone resistance in the Pseudomonas aeruginosa parC gene
    T Deguchi
    Department of Urology, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu 500 8705, Japan
    J Infect Chemother 6:26-9. 2000
  4. ncbi request reprint Treatment of uncomplicated gonococcal urethritis by double-dosing of 200 mg cefixime at a 6-h interval
    Takashi Deguchi
    Department of Urology, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu 500 8705, Japan
    J Infect Chemother 9:35-9. 2003
  5. ncbi request reprint Loss of tissue immunoreactive androgen receptor in prostate cancer presenting initially as an intracranial tumor
    H Ehara
    Department of Urology and Pathology, Gifu University School of Medicine, Gifu City, Japan
    Urol Int 63:130-2. 1999
  6. ncbi request reprint Association of Ureaplasma urealyticum (biovar 2) with nongonococcal urethritis
    Takashi Deguchi
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Sex Transm Dis 31:192-5. 2004
  7. pmc Longitudinal quantitative detection by real-time PCR of Mycoplasma genitalium in first-pass urine of men with recurrent nongonococcal urethritis
    Takashi Deguchi
    Department of Urology, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu City, Gifu 500 8705, Japan
    J Clin Microbiol 40:3854-6. 2002
  8. ncbi request reprint [Detection of Neisseria gonorrhoeae in first-voided urine sediments from male urethritis patients by polymerase chain reaction]
    H Komeda
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 66:1209-12. 1992
  9. ncbi request reprint [Detection of Mycoplasma genitalium from male patients with non-gonococcal urethritis by polymerase chain reaction]
    H Komeda
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 68:1376-80. 1994
  10. ncbi request reprint [Detection of Chlamydia trachomatis from urethral swab in male urethritis by polymerase chain reaction]
    T Deguchi
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 65:1555-9. 1991

Detail Information

Publications93

  1. pmc Threat to cefixime treatment for gonorrhea
    Shigeaki Yokoi
    Emerg Infect Dis 13:1275-7. 2007
  2. pmc Alteration in the GyrA subunit of DNA gyrase and the ParC subunit of DNA topoisomerase IV in quinolone-resistant clinical isolates of Staphylococcus epidermidis
    Z Li
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Antimicrob Agents Chemother 42:3293-5. 1998
    ..The simultaneous presence of GyrA and ParC alterations was associated with a high level of fluoroquinolone resistance in the clinical isolates of S. epidermidis...
  3. ncbi request reprint Development of a rapid assay for screening point mutations associated with quinolone resistance in the Pseudomonas aeruginosa parC gene
    T Deguchi
    Department of Urology, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu 500 8705, Japan
    J Infect Chemother 6:26-9. 2000
    ..This rapid and simple assay could be a useful screening device for genetic alterations associated with resistance to quinolones in the P. aeruginosa parC gene...
  4. ncbi request reprint Treatment of uncomplicated gonococcal urethritis by double-dosing of 200 mg cefixime at a 6-h interval
    Takashi Deguchi
    Department of Urology, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu 500 8705, Japan
    J Infect Chemother 9:35-9. 2003
    ..This regimen would not be effective against infection by strains exhibiting cefixime MIC(90)s of > or =0.125 microg/ml. For such strains, a different regimen with a higher dose of cefixime would be required...
  5. ncbi request reprint Loss of tissue immunoreactive androgen receptor in prostate cancer presenting initially as an intracranial tumor
    H Ehara
    Department of Urology and Pathology, Gifu University School of Medicine, Gifu City, Japan
    Urol Int 63:130-2. 1999
    ..In this case, the androgen-independent growth and rapid progression might be associated with the initial loss of the antigen and androgen characteristics of the prostate...
  6. ncbi request reprint Association of Ureaplasma urealyticum (biovar 2) with nongonococcal urethritis
    Takashi Deguchi
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Sex Transm Dis 31:192-5. 2004
    ..urealyticum (biovar 2), but association of each of these species with nongonococcal urethritis (NGU) remains unclear...
  7. pmc Longitudinal quantitative detection by real-time PCR of Mycoplasma genitalium in first-pass urine of men with recurrent nongonococcal urethritis
    Takashi Deguchi
    Department of Urology, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu City, Gifu 500 8705, Japan
    J Clin Microbiol 40:3854-6. 2002
    ..We observed regrowth of M. genitalium persisting in hosts after treatment and a possible association of the increase in the M. genitalium load with emergence of symptoms and signs of nongonococcal urethritis in four of these patients...
  8. ncbi request reprint [Detection of Neisseria gonorrhoeae in first-voided urine sediments from male urethritis patients by polymerase chain reaction]
    H Komeda
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 66:1209-12. 1992
    ..6% (43/45). PCR procedure for detection of pathogens from first-voided urine sediments would be noninvasive and would be applied for the diagnosis of gonococcal urethritis and chlamydial urethritis...
  9. ncbi request reprint [Detection of Mycoplasma genitalium from male patients with non-gonococcal urethritis by polymerase chain reaction]
    H Komeda
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 68:1376-80. 1994
    ..The prevalence of M. genitalium in NGU and in Chlamydia-negative NGU was significantly higher than that in the normal control. These findings suggest that M. genitalium would be a cause of NGU...
  10. ncbi request reprint [Detection of Chlamydia trachomatis from urethral swab in male urethritis by polymerase chain reaction]
    T Deguchi
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 65:1555-9. 1991
    ..In two specimens concluded s negative by culture method, amplified C. trachomatis DNA were detected by PCR. Thus, the PCR would be a more simple and sensitive method for detection of C. trachomatis, compared with the culture method...
  11. ncbi request reprint [Comparison of polymerase chain reaction and IDEIA Chlamydia in detection of Chlamydia trachomatis from first-voided urine of male urethritis patients]
    H Komeda
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 66:1473-8. 1992
    ..6% (65/68) respectively, resulting in a high overall coincidence rate at 95%. Thus, the improved method with PCR using FVU as a specimen is proved to be a useful, non-invasive diagnostic tool for diagnosis of chlamydial urethritis...
  12. ncbi request reprint [Detection of Chlamydia trachomatis in first-voided urine sediments from male urethritis by polymerase chain reaction]
    H Komeda
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 66:831-6. 1992
    ..7% (88/97). Detection of C. trachomatis from first-voided urine sediments by PCR was considered to be noninvasive and useful for the diagnosis of male urethritis due to C. trachomatis...
  13. ncbi request reprint [Detection of Neisseria gonorrhoeae from male patients with urethritis by polymerase chain reaction]
    T Deguchi
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 66:555-60. 1992
    ..5% (64/67). Thus, the PCR procedure developed in this study was sensitive and specific for detection of N. gonorrhoeae and could be applied for diagnosis of gonococcal urethritis...
  14. ncbi request reprint [Detection of Ureaplasma urealyticum by polymerase chain reaction]
    K Tada
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 66:1621-7. 1992
    ..Thus, the PCR procedure was shown to be a simple, rapid and specific method for detection of U. urealyticum and could be applied to detection of U. urealyticum from clinical specimens...
  15. pmc Detection of micrometastatic prostate cancer cells in the bone marrow of patients with prostate cancer
    T Deguchi
    Department of Urology, Gifu University School of Medicine, Gifu shi, Japan
    Br J Cancer 75:634-8. 1997
    ....
  16. ncbi request reprint Comparison of in vitro antimicrobial activity of AM-1155 with those of tosufloxacin and fleroxacin against clinical isolates of Neisseria gonorrhoeae harboring quinolone resistance alterations in GyrA and ParC
    T Deguchi
    Department of Urology, Gifu University, Japan
    Chemotherapy 43:239-44. 1997
    ..Because of its potent in vitro antimicrobial activity and advantageous pharmacokinetic behavior, AM-1155 may be a clinically useful agent for treating gonorrhea including that caused by quinolone-resistant strains...
  17. ncbi request reprint Association of Mycoplasma genitalium persistence in the urethra with recurrence of nongonococcal urethritis
    S I Maeda
    Department of Urology, Toyota Memorial Hospital, Toyota, Japan
    Sex Transm Dis 28:472-6. 2001
    ..CONCLUSIONS: This study suggests that the persistence of M genitalium in the urethra may be associated with recurrence of nongonococcal urethritis...
  18. ncbi request reprint In vivo selection of Pseudomonas Aeruginosa with decreased susceptibilities to fluoroquinolones during fluoroquinolone treatment of urinary tract infection
    M Nakano
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Urology 58:125-8. 2001
    ..We should be aware that inappropriate use of fluoroquinolones could select such a strain harboring a quinolone resistance-associated alteration of DNA gyrase...
  19. ncbi request reprint [Comparison of polymerase chain reaction and enzyme immunoassay (Chlamydiazyme) in detection of Chlamydia trachomatis from male urethritis]
    T Deguchi
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 66:172-6. 1992
    ..9% (29/33). The overall coincidence rate between the two methods was high (94.6%). Thus, the PCR method was more sensitive than Chlamydiazyme for detection of C. trachomatis and specific for diagnosis of chlamydial urethritis...
  20. ncbi request reprint The role of Mycoplasma genitalium and Ureaplasma urealyticum biovar 2 in postgonococcal urethritis
    Shigeaki Yokoi
    Department of Urology, Graduate School of Medicine, Gifu University, Gifu, Japan
    Clin Infect Dis 45:866-71. 2007
    ..Thus, we conducted a study to determine the prevalence of coinfection with genital mycoplasmas and ureaplasmas among men with GU and to assess the role of these pathogens in PGU...
  21. ncbi request reprint Uncommon occurrence of fluoroquinolone resistance-associated alterations in GyrA and ParC in clinical strains of Chlamydia trachomatis
    Shigeaki Yokoi
    Department of Urology, Graduate School of Medicine, Gifu University, 1 1 Yanagaido, Gifu, 501 1194, Japan
    J Infect Chemother 10:262-7. 2004
    ..The present study suggests that fluoroquinolone resistance-associated alterations in GyrA and ParC may be uncommon in clinical strains of C. trachomatis...
  22. doi request reprint Emergence of clinical strains of Mycoplasma genitalium harbouring alterations in ParC associated with fluoroquinolone resistance
    Yasushi Shimada
    Department of Urology, Graduate School of Medicine, Gifu University, 1 1 Yanagido, Gifu 501 1194, Japan
    Int J Antimicrob Agents 36:255-8. 2010
    ..M. genitalium harbouring mutations associated with fluoroquinolone resistance in the parC gene may have emerged clinically and the prevalence may be ca. 10% in Japan...
  23. pmc Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in Central Japan
    Masayasu Ito
    Department of Urology, Gifu University School of Medicine, 1 1 Yanagido, Gifu City 501 1194, Japan
    Antimicrob Agents Chemother 49:137-43. 2005
    ..The emergence of such strains may be the result of the in vivo generation of clones in which interspecies recombination occurred between the penA genes of N. gonorrhoeae and commensal Neisseria species...
  24. ncbi request reprint Tonsillectomy and steroid pulse therapy for recurrent IgA nephropathy in renal allograft
    T Tsuchiya
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Clin Nephrol 73:68-71. 2010
    ..Tonsillectomy combined with steroid pulse therapy can induce clinical remission in patients with recurrent IgAN after renal transplantation...
  25. ncbi request reprint Mycoplasma genitalium: another important pathogen of nongonococcal urethritis
    Takashi Deguchi
    Departments of Urology, Gifu University School of Medicine, Gifu, and Toyota Memorial Hospital, Toyota, Japan
    J Urol 167:1210-7. 2002
    ..We reviewed findings on the pathogenic role of Mycoplasma genitalium in nongonococcal urethritis and the treatment of men with M. genitalium positive nongonococcal urethritis...
  26. ncbi request reprint Treatment of men with urethritis negative for Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum
    Shin ichi Maeda
    Department of Urology, Toyota Memorial Hospital, Toyota, Japan
    Int J Urol 14:422-5. 2007
    ..trachomatis-positive NGU have been performed. We assessed the efficacy of antimicrobial agents that are active against C. trachomatis on non-mycoplasmal, non-ureaplasmal and non-chlamydial NGU (NMNUNCNGU)...
  27. pmc Remarkable increase in central Japan in 2001-2002 of Neisseria gonorrhoeae isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones
    Masayasu Ito
    Department of Urology, Gifu University School of Medicine, Gifu City, Gifu, Japan
    Antimicrob Agents Chemother 48:3185-7. 2004
    ..The majority was sensitive to ceftriaxone and spectinomycin, but a remarkable increase in isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones was observed from 2001 through 2002...
  28. doi request reprint Effect of conversion from twice-daily to once-daily tacrolimus on glucose intolerance in stable kidney transplant recipients
    T Tsuchiya
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Transplant Proc 44:118-20. 2012
    ..The main aim of this study was to evaluate the effect of conversion from twice-daily tacrolimus (tacrolimus-BID) to once-daily tacrolimus (tacrolimus-OD) on glucose intolerance in stable kidney transplant patients...
  29. ncbi request reprint Pathologic significance of Staphylococcus saprophyticus in complicated urinary tract infections
    S Ishihara
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Urology 57:17-20. 2001
    ..CONCLUSIONS: Although this organism is pathogenic in certain circumstances, suggesting the necessity of preoperative antimicrobial elimination, it is usually a colonizer in complicated urinary tract infections...
  30. ncbi request reprint Expression of mitotic Aurora/Ipl1p-related kinases in renal cell carcinomas: an immunohistochemical study
    Hidetoshi Ehara
    Department of Urology, Gifu University School of Medicine, 40 Tsukasa, Gifu 500 8705, Japan
    Urol Res 31:382-6. 2003
    ..Although the precise physiological functions of these kinases are not known, AIRK subfamily expression may play a role in renal cell carcinoma tumorigenesis...
  31. doi request reprint Azithromycin treatment for nongonococcal urethritis negative for Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum
    Shin ichi Maeda
    Department of Urology, Toyota Memorial Hospital, Toyota, Aichi, Japan
    Int J Urol 16:215-6. 2009
    ..A single dose of 1 g azithromycin, which is effective not only for NGU due to specific pathogens but also for NMNUNCNGU, is an appropriate treatment for NGU...
  32. ncbi request reprint Mycoplasma genitalium urethritis in men
    Satoshi Ishihara
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Int J Antimicrob Agents 24:S23-7. 2004
    ..genitalium-positive NGU. Further studies are required to establish the optimal chemotherapy for M. genitalium-positive NGU...
  33. ncbi request reprint Role of local 11 beta-hydroxysteroid dehydrogenase type 2 expression in determining the phenotype of adrenal adenomas
    Tomoatsu Mune
    Third Department of Internal Medicine, Gifu University School of Medicine, Gifu 500 8705, Japan
    J Clin Endocrinol Metab 88:864-70. 2003
    ..Nonfunctioning adenomas and those causing preclinical and overt Cushing's syndrome may represent a continuum with clinical manifestations depending mainly on tumor size and HSD11B2 expression levels...
  34. ncbi request reprint Chemopreventive effects of a flavonoid antioxidant silymarin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice
    Pham Quang Vinh
    Department of Urology, Gifu University School of Medicine, Gifu 500 8705, Japan
    Jpn J Cancer Res 93:42-9. 2002
    ..These findings suggest that silymarin is effective in preventing OH-BBN-induced bladder carcinogenesis in mice...
  35. doi request reprint Renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion: radiological findings mimicking papillary subtype
    Hiroki Kato
    Department of Radiology, Gifu University School of Medicine, Gifu, Japan
    J Magn Reson Imaging 33:217-20. 2011
    ..Therefore, Xp11 translocation carcinoma should be considered, particularly in young patients when radiologic images demonstrate a renal tumor mimicking the papillary subtype...
  36. doi request reprint Emergence and spread of drug resistant Neisseria gonorrhoeae
    Takashi Deguchi
    Department of Urology, Graduate School of Medicine, Gifu University, Gifu, Japan
    J Urol 184:851-8; quiz 1235. 2010
    ..We review drug resistance in N. gonorrhoeae with a particular emphasis on resistance to fluoroquinolones, cefixime and azithromycin...
  37. ncbi request reprint Rapid detection of quinolone resistance-associated gyrA mutations in Neisseria gonorrhoeae with a LightCycler
    Zhiyu Li
    Department of Urology, Gifu University School of Medicine, Japan
    J Infect Chemother 8:145-50. 2002
    ..The mutation status in the gyrA gene assessed by the LightCycler assay was completely in agreement with the results of our previous conventional sequencing analysis, and was associated with the susceptibility to ciprofloxacin...
  38. ncbi request reprint Antimicrobial activity of imipenem against isolates from complicated urinary tract infections
    Satoshi Ishihara
    Department of Urology, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu 500 8705, Japan
    Int J Antimicrob Agents 19:565-9. 2002
    ..Resistant strains were rare in other major uropathogenic species. These results suggest that imipenem is still one of the most reliable antimicrobial drugs...
  39. doi request reprint Microbiological outcome of complicated urinary tract infections treated with levofloxacin: a pharmacokinetic/pharmacodynamic analysis
    Takashi Deguchi
    Department of Urology, Graduate School of Medicine, Gifu University, 1 1 Yanagido, Gifu 501 1194, Japan
    Int J Antimicrob Agents 35:573-7. 2010
    ..faecalis were <1. These findings suggested that, in addition to its plasma concentration, the high concentration of levofloxacin in the urine might play a role in eradicating bacteria...
  40. doi request reprint Failure to detect Mycoplasma genitalium in the pharynges of female sex workers in Japan
    Takashi Deguchi
    Department of Urology, Graduate Medical School of Medicine, Gifu University, 1 1 Yanagido, Gifu, Gifu, 501 1194, Japan
    J Infect Chemother 15:410-3. 2009
    ..M. hominis, U. parvum, and U. urealyticum were detected in throat washings, but M. genitalium was not. These findings do not necessarily rule out the transmission of M. genitalium from the pharynx to the urethra by orogenital sex...
  41. doi request reprint Thyroidization in renal allografts
    Shinichi Ito
    Department of Urology, Graduate School of Medical Science, Gifu University, Gifu, Japan
    Clin Transplant 23:6-9. 2009
    ..Such subclinical urological diseases in the grafts might affect the prognosis of renal function. Therefore, appropriate management of urinary tract diseases is required...
  42. ncbi request reprint [Detection of Chlamydia trachomatis by polymerase chain reaction]
    T Deguchi
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 65:1183-7. 1991
    ..Thus, the PCR was shown to be specific for C. trachomatis and more sensitive than the enzyme immunoassays for detection of chlamydial antigen and the chlamydial rRNA:DNA probe hybridization method...
  43. ncbi request reprint [Clinical evaluation of SD-8828 (antibody coated bacteria assay kit) in urinary tract infection]
    Y Harada
    Department of Urology, Gifu University School of Medicine
    Kansenshogaku Zasshi 66:1283-7. 1992
    ..The overall coincidence rate was high (91.7%). This SD-8828, a new simple assay for ACB, which detects IgG alternating the plate method, may be used as a convenient method in clinical practice...
  44. ncbi request reprint Essential roles of ERK-mediated phosphorylation of vinexin in cell spreading, migration and anchorage-independent growth
    K Mizutani
    Department of Urology, Gifu University School of Medicine, 1 1 Yanagido, Gifu, Japan
    Oncogene 26:7122-31. 2007
    ..Taken together, ERK-mediated phosphorylation of vinexinbeta is strongly suggested to occur in a spatio-temporally regulated manner and play important roles in cell spreading, migration and anchorage-independent growth...
  45. ncbi request reprint Role of local 11beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) expression in determining the phenotype of adrenal adenomas
    Tomoatsu Mune
    Third Department of Internal Medicine, Gifu University School of Medicine, Gifu 500 8705, Japan
    Endocr Res 28:751-2. 2002
  46. pmc Cultivation of Neisseria gonorrhoeae in liquid media and determination of its in vitro susceptibilities to quinolones
    Masaya Takei
    Department of Urology, Gifu University School of Medicine, Japan
    J Clin Microbiol 43:4321-7. 2005
    ..25 to 0.5 times the MIC, gonococcal growth was comparable to that of the growth control. These results suggest that the cultivation of N. gonorrhoeae by use of FB may be useful for evaluation of the antibacterial effects of quinolones...
  47. ncbi request reprint [Testicular pure teratoma: a case report]
    T Tsuchiya
    Department of Urology, Gifu University School of Medicine
    Hinyokika Kiyo 47:117-9. 2001
    ..Despite its histologically benign appearance, primary pure teratoma of the testis has a metastatic and recurrent potential. Therefore, primary pure teratoma should be man aged in the same way as other nonseminomatous germ cell tumors...
  48. ncbi request reprint In vitro activity of fluoroquinolones against Mycoplasma genitalium and their bacteriological efficacy for treatment of M. genitalium-positive nongonococcal urethritis in men
    M Yasuda
    Division of Disease Control, Research Field of Medical Sciences, Department of Urology, Graduate School of Medicine, Gifu University, Gifu, Japan
    Clin Infect Dis 41:1357-9. 2005
    ..In vitro, levofloxacin was less active than gatifloxacin, tosufloxacin, and sparfloxacin. In vivo, the bacteriological efficacy of gatifloxacin was superior to that of levofloxacin or tosufloxacin...
  49. ncbi request reprint Immunohistochemical analysis with multiple antibodies in search of prognostic markers for clear cell renal cell carcinoma
    Nguyen Ba Phuoc
    Department of Urology, Gifu University Graduate School of Medicine, Gifu, Japan
    Urology 69:843-8. 2007
    ..To simultaneously analyze multiple biologic markers to identify strong prognostic markers for disease-specific survival of patients with clear cell renal cell carcinoma (ccRCC)...
  50. ncbi request reprint Failure to detect urethral Trichomonas vaginalis in Japanese men with or without urethritis
    Shin ichi Maeda
    Department of Urology, Toyota Memorial Hospital, Toyota, Japan
    Int J Urol 13:1418-20. 2006
    ..The aim of this study was to determine the prevalence and morbidity of T. vaginalis infection in Japanese men...
  51. ncbi request reprint Prognostic value of the co-expression of carbonic anhydrase IX and vascular endothelial growth factor in patients with clear cell renal cell carcinoma
    Nguyen Ba Phuoc
    Department of Urology, Gifu University Graduate School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
    Oncol Rep 20:525-30. 2008
    ..Furthermore, the co-expression data for CAIX-VEGF provide more accurate prognostic information than the individual data. This information may be useful for survival prediction and risk stratification of patients with ccRCC...
  52. ncbi request reprint Expression of clusterin, XIAP and survivin, and their changes by camptothecin (CPT) treatment in CPT-resistant PC-3 and CPT-sensitive LNCaP cells
    K Mizutani
    Department of Urology, Gifu University Graduate School of Medicine, 1 1 Yanagido, Gifu, Gifu 5011194, Japan
    Exp Oncol 28:209-15. 2006
    ..In the current study, we investigated their expression levels in human prostate cancer cell lines, LNCaP and PC-3 which are sensitive and resistant to camptothecin (CPT), topoisomerase I inhibitor, respectively...
  53. ncbi request reprint Bacillus okuhidensis sp. nov., isolated from the Okuhida spa area of Japan
    Zhiyu Li
    Department of Urology, Gifu University School of Medicine, Japan
    Int J Syst Evol Microbiol 52:1205-9. 2002
    ..On the basis of phylogenetic evidence and phenotypic distinctiveness, a new species, Bacillus okuhidensis sp. nov., is proposed. The type strain of Bacillus okuhidensis is GTC 854T (= JCM 10945T = DSM 13666T)...
  54. ncbi request reprint System for simultaneous detection of 16 pathogens related to urethritis to diagnose mixed infection
    Naruyasu Masue
    Department of Urology, Gifu University, Graduate School of Medicine, Gifu, Japan
    Int J Urol 14:39-42. 2007
    ..Urethritis is not always caused by a single pathogen, and isolation of more than two pathogens from one patient is not uncommon. We developed a method to simultaneously detect 16 pathogens related to urethritis...
  55. ncbi request reprint Prognostic factors for survival of patients after curative surgery for renal cell carcinoma: multivariate analysis of 482 cases
    Masahiro Uno
    Department of Urology, Ogaki Municipal Hospital, 4 86 Minaminokawa, Ogaki, Gifu, 503 8502, Japan
    Int J Clin Oncol 9:510-4. 2004
    ..Even with curative surgery, renal cell carcinoma occasionally recurs in other organs, with fatal results. In this study, we identified independent prognostic factors for survival in patients with renal cell carcinoma after curative surgery...
  56. doi request reprint Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells
    Yasunori Fujita
    Department of Longevity and Aging Research, Gifu International Institute of Biotechnology, Kakamigahara, Gifu, Japan
    Biochem Biophys Res Commun 377:114-9. 2008
    ....
  57. ncbi request reprint Significance of an E-cadherin gene promoter polymorphism for risk and disease severity of prostate cancer in a Japanese population
    Takahiro Goto
    Department of Urology, Graduate School of Medicine, Gifu University, Gifu, Japan
    Urology 70:127-30. 2007
    ..To explore the significance of an E-cadherin gene promoter polymorphism for risk and disease severity of prostate cancer in a Japanese population...
  58. doi request reprint The potential role of prebiopsy magnetic resonance imaging combined with prostate-specific antigen density in the detection of prostate cancer
    Yasuaki Kubota
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Int J Urol 15:322-6; discussion 327. 2008
    ..Thus, we evaluated the combination of MR imaging and PSA density (PSAD) for specificity and sensitivity...
  59. ncbi request reprint Spontaneous disappearance of multiple lung metastases after nephroureterectomy from sarcomatoid carcinoma of the renal pelvis: a case report
    Naruyasu Masue
    Department of Urology, Matsunami General Hospital, Gifu University, Gifu, Japan
    Int J Urol 14:75-8. 2007
    ..Approximately 5 months later, CT revealed that the lung metastases had disappeared. There has been no evidence of disease for 46 months postoperatively...
  60. doi request reprint Nocturia in men less than 50 years of age may be associated with obstructive sleep apnea syndrome
    Yoji Moriyama
    Department of Urology, Gifu University School of Medicine, Gifu, Japan
    Urology 71:1096-8. 2008
    ..To assess the prevalence of nocturia in association with other voiding symptoms in men with obstructive sleep apnea syndrome (OSAS)...
  61. ncbi request reprint [Multiple metastases of the penile cancer: an experience of combination chemotherapy]
    Kosuke Mizutani
    Department of Urology, Gifu University School of Medicine
    Hinyokika Kiyo 50:223-6. 2004
    ..However, the tumors were aggressive and did not respond to the therapy. We discuss the use of combination chemotherapy in the case of advanced penile cancer...
  62. ncbi request reprint [Voiding function and sexual activity in patients following Hautmann neobladder construction]
    Mitsuhiro Taniguchi
    Department of Urology, Gifu Prefectural Hospital, Gifu, Japan
    Nihon Hinyokika Gakkai Zasshi 93:694-701. 2002
    ..We retrospectively evaluated the outcome of Hautmann neobladder reconstruction in terms of complications, lower urinary tract symptoms, and sexual function in a large group of patients who underwent radical cystectomy...
  63. ncbi request reprint [Bilateral laparoscopic adrenalectomy in ACTH-independent macronodular adrenal hyperplasia: a case report]
    Toru Yamada
    Department of Urology, Gifu University School of Medicine
    Hinyokika Kiyo 48:431-4. 2002
    ..The postoperative course was uneventful. We believe that simultaneous bilateral laparoscopic adrenalectomy is feasible, safe, and results in minimal postoperative morbidity for the treatment of AIMAH...
  64. ncbi request reprint Quantitative detection of Ureaplasma parvum (biovar 1) and Ureaplasma urealyticum (biovar 2) in urine specimens from men with and without urethritis by real-time polymerase chain reaction
    Takashi Yoshida
    Research and Development, Mitsubishi Kagaku Bio Clinical Laboratories, Inc, Itabashi, Tokyo, Japan
    Sex Transm Dis 34:416-9. 2007
    ..We also found that the presence of Ureaplasma parvum (biovar 1) in the male urethra might be the result of colonization...
  65. ncbi request reprint Decreased affinity of mosaic-structure recombinant penicillin-binding protein 2 for oral cephalosporins in Neisseria gonorrhoeae
    Susumu Ochiai
    Research and Development Department, Mitsubishi Kagaku Bio Clinical Laboratories, Inc, 3 30 1 Shimura, Itabashi ku, Tokyo 174 8555, Japan
    J Antimicrob Chemother 60:54-60. 2007
    ..The aim of this study was to determine the affinity of mosaic PBP 2 for cephalosporins in N. gonorrhoeae...
  66. pmc Rapid detection of the mosaic structure of the Neisseria gonorrhoeae penA Gene, which is associated with decreased susceptibilities to oral cephalosporins
    Susumu Ochiai
    Advanced Medicine Development Department, R and D and Business Development Segment, Mitsubishi Chemical Medience Corporation, 3 30 1 Shimura, Itabashi ku, Tokyo 174 8555, Japan
    J Clin Microbiol 46:1804-10. 2008
    ..This real-time PCR assay for the detection of mosaic PBP 2 of N. gonorrhoeae is thus useful in the prediction of decreased susceptibilities to oral cephalosporins...
  67. pmc Quantitative detection of Mycoplasma genitalium from first-pass urine of men with urethritis and asymptomatic men by real-time PCR
    Takashi Yoshida
    Research and Development Department, Mitsubishi Kagaku Bio Clinical Laboratories, Inc, Tokyo 174 8555, Japan
    J Clin Microbiol 40:1451-5. 2002
    ..05). The quantitative assessment of M. genitalium loads by the TaqMan assay will provide useful information for understanding the pathogenicity of this mycoplasma in the urogenital tract...
  68. pmc Rapid detection of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum organisms in genitourinary samples by PCR-microtiter plate hybridization assay
    Takashi Yoshida
    Research and Development, Mitsubishi Kagaku Bio Clinical Laboratories, Inc, Itabashi, Tokyo 174 8555, Japan
    J Clin Microbiol 41:1850-5. 2003
    ..Based on these results, this PCR-microtiter plate hybridization assay can be considered an effective tool for the diagnosis of genitourinary infections with mycoplasmas or ureaplasmas...
  69. ncbi request reprint Lack of nationwide surveillance of antimicrobial resistance of Neisseria gonorrhoeae in Japan
    Takashi Deguchi
    Ann Intern Med 149:363-4. 2008
  70. ncbi request reprint Urinary tract-derived Escherichia coli resistant to co-trimoxazole in Japan, where the drug is seldom used for treating acute urinary tract infections
    Satoshi Ishihara
    J Antimicrob Chemother 49:881-2. 2002
  71. ncbi request reprint Detection of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum (biovar 1) and Ureaplasma urealyticum (biovar 2) in patients with non-gonococcal urethritis using polymerase chain reaction-microtiter plate hybridization
    Shin ichi Maeda
    Japanese Research Group for UTI, Kitakyushu, Japan
    Int J Urol 11:750-4. 2004
    ....
  72. ncbi request reprint Quantitative detection and phylogeny-based identification of mycoplasmas and ureaplasmas from human immunodeficiency virus type 1-positive patients
    Osamu Hashimoto
    Research and Development Department, Mitsubishi Kagaku Bio Clinical Laboratories Inc, 3 30 1 Shimura, Itabashi ku, Tokyo 174 8555, Japan
    J Infect Chemother 12:25-30. 2006
    ..8 x 10 copies/ml to 7.2 x 10(3) copies/ml. Overall, this study demonstrates that real-time PCR and phylogenetic analysis are the fastest available methods for the detection of mycoplasmas in the urogenital tract...
  73. ncbi request reprint [Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2003). I. Susceptibility distribution]
    Yoshiaki Kumamoto
    Department of Urology, Sapporo Medical University School of Medicine
    Jpn J Antibiot 58:518-43. 2005
    ..The antibacterial activity of CZOP was relatively good (MIC50: 2 microg/mL)...
  74. pmc Phylogeny-based rapid identification of mycoplasmas and ureaplasmas from urethritis patients
    Takashi Yoshida
    Infectious Disease Laboratory, Mitsubishi Kagaku Bio Clinical Laboratories, Inc, Shimura 3 30 1, Itabashi, Tokyo 174 8555, Japan
    J Clin Microbiol 40:105-10. 2002
    ..genitalium and U. urealyticum. This phylogeny-based identification of mycoplasmas and ureaplasmas provides not only a powerful tool for rapid diagnosis but also the basis for etiological studies of these pathogens...
  75. ncbi request reprint Polymerase chain reaction-based subtyping of ureaplasma parvum and ureaplasma urealyticum in first-pass urine samples from men with or without urethritis
    Takashi Yoshida
    Research and Development Department 1, Mitsubishi Kagaku Bio Clinical Laboratories, Inc, Tokyo, Japan
    Sex Transm Dis 32:454-7. 2005
    ..urealyticum into 3 subtypes: subtype 1 (serovars 2, 5, 8, and 9), subtype 2 (serovars 4, 10, 12, and 13), and subtype 3 (serovars 7 and 11)...
  76. ncbi request reprint [Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2004). I. Susceptibility distribution]
    Yoshiaki Kumamoto
    Department of Urology, Sapporo Medical University School of Medicine
    Jpn J Antibiot 59:177-200. 2006
    ..The antibacterial activities of CZOP and CAZ were considered to be relatively good on MIC50 comparison (MIC50: 2 microg/mL)...
  77. ncbi request reprint [Questionnaire survey on the theory of antimicrobial prophylaxis in urologic surgery]
    Shingo Yamamoto
    Department of Urology, Graduate School of Medicine, Kyoto University
    Hinyokika Kiyo 50:779-86. 2004
    ..Thus, further well-designed clinical trials are required to establish original guidelines in Japan...
  78. ncbi request reprint [Urethral recurrence and distant metastases of bladder cancer 9 years after cystectomy and neobladder]
    Seiichi Kato
    Department of Urology, Gifu Municipal Hospital
    Hinyokika Kiyo 51:195-7. 2005
    ..Chemotherapy was not performed and the patient died 5 months later. We concluded that long-term follow-up for urethral recurrence in women with neobladders was necessary...
  79. ncbi request reprint [Recurrence of bladder cancer in fossa navicularis 17 months after cystourethrectomy: a case report]
    Keita Nakane
    The Department of Urology, Gifu University Graduate School of Medicine
    Hinyokika Kiyo 51:631-3. 2005
    ..Histopathological findings showed urothelial carcinoma pTa, G2>G3, which was identical to primary tumor. Tumor had not invaded the corpus cavernosum. Careful follow-up of the patients with preservation of fossa navicularis is important...
  80. ncbi request reprint [A case of renal pelvic tumor due to phenacetin abuse]
    Keitarou Kojima
    Department of Urology, Toyota Memorial Hospital
    Hinyokika Kiyo 48:293-6. 2002
    ..Histopathological diagnosis was grade 2 transitional cell carcinoma. Interstitial nephritis was also observed. Our case is the twenty-second report of an urinary tract tumor associated with phenacetin abuse in Japan...
  81. ncbi request reprint Association of Lys173Arg polymorphism with CYP11B2 expression in normal adrenal glands and aldosterone-producing adenomas
    Hiromichi Tanahashi
    Department of Diabetes and Endocrinology, Room 2S15, Gifu University, 1 1 Yanagido, Gifu 501 1194, Japan
    J Clin Endocrinol Metab 90:6226-31. 2005
    ..These polymorphisms have been associated with cardiovascular parameters, including hypertension, but not directly with gene expression...
  82. ncbi request reprint [Four cases of idiopathic retroperitoneal fibrosis markedly responsive to steroid therapy]
    Yasuaki Kubota
    The Department of Urology, Toyota Memorial Hospital
    Hinyokika Kiyo 51:315-9. 2005
    ..Prominent calcification in the wall of the abdominal aorta indicated that the arteriosclerosis was related to IRPF. We measured serum antibodies for Chlamydia pneumoniae in four cases...
  83. ncbi request reprint Efficacy of 1-day prophylaxis medication with fluoroquinolone for prostate biopsy
    Katsumi Shigemura
    Division of Urology, Department of Organs Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    World J Urol 23:356-60. 2005
    ..We can perform PBX safely with levofloxacin at 600 mg for 1 day as prophylaxis and recommend this method from the point of view of the decrease of antibiotic-resistant strains...
  84. ncbi request reprint [Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2002). III. Secular changes in susceptibility]
    Yoshiaki Kumamoto
    Department of Urology, Sapporo Medical University School of Medicine
    Jpn J Antibiot 57:311-403. 2004
    ..2% (2/9 strains) in the uncomplicated UTIs group and 3.6% (2/56 strains) in the complicated UTIs group...
  85. ncbi request reprint [Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2002). II. Background of patients]
    Yoshiaki Kumamoto
    Department of Urology, Sapporo Medical University School of Medicine
    Jpn J Antibiot 57:275-87. 2004
    ..E. faecalis was more frequently isolated in the patients with surgery in uncomplicated and complicated UTIs without indwelling catheter and in the patients without surgery in complicated UTIs with indwelling catheter...
  86. ncbi request reprint Abscess of the corpus cavernosum
    Hidetoshi Ehara
    Int J Infect Dis 11:553-4. 2007
  87. ncbi request reprint [Bilateral renal cell carcinoma associated with polycystic kidney disease: case report and literature review]
    Taku Kato
    The Department of Urology, Gifu University, Graduate School of Medicine
    Hinyokika Kiyo 53:117-9. 2007
    ..Renal cell carcinoma in patients with end-stage renal disease is fairly common and is associated with acquired cystic kidney disease. However, renal cell carcinoma associated with polycystic kidney disease is extremely rare...
  88. ncbi request reprint [Clinical evaluation of our first 50 laparoscopic adrenalectomies]
    Shingo Kamei
    The Department of Urology, Gifu University Graduate School of Medicine
    Hinyokika Kiyo 53:107-12. 2007
    ..As our experience with laparoscopic adrenalectomy increased, operation time decreased. Laparoscopic adrenalectomy should be used more widely in the future...
  89. ncbi request reprint [Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2002). I. Susceptibility distribution]
    Yoshiaki Kumamoto
    Department of Urology, Sapporo Medical University School of Medicine
    Jpn J Antibiot 57:246-74. 2004
    ..The antibacterial activity of CZOP was relatively good (MIC50: 8 microg/mL)...
  90. ncbi request reprint [Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2004). III. Secular changes in susceptibility]
    Yoshiaki Kumamoto
    Department of Urology, Sapporo Medical University School of Medicine
    Jpn J Antibiot 59:217-315. 2006
    ..The susceptibility of P. aeruginosa isolated from complicated UTIs has been stable against amikacin (AMK). For annual changes in MIC50, TOB and IPM had a relatively stable and high activity (MIC50: 0.5-2 microg/mL)...
  91. ncbi request reprint [Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2003). III. Secular changes in susceptibility]
    Yoshiaki Kumamoto
    Department of Urology, Sapporo Medical University School of Medicine
    Jpn J Antibiot 58:557-654. 2005
    ..125 microg/mL against uncomplicated UTIs, 0.25 microg/mL against complicated UTIs) like meropenem. The drug sensitivity of P. aeruginosa was generally low and was not much different from that in up to the previous years...
  92. ncbi request reprint [Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2003). II. Background of patients]
    Yoshiaki Kumamoto
    Department of Urology, Sapporo Medical University School of Medicine
    Jpn J Antibiot 58:544-56. 2005
    ..coli was more frequently isolated in the patients without surgery, while P. aeruginosa and E. faecalis were more frequently isolated in the patients with surgery in any UTIs...
  93. ncbi request reprint [Recurrent spontaneous bladder rupture cured by conservative therapy: a case report]
    Noriyasu Hagiwara
    Department of Urology, Ogaki Municipal Hospital
    Hinyokika Kiyo 48:367-70. 2002
    ..Urinary diversion and augmentation cystoplasty should be considered for repeated rupture of the bladder...