H Funatsu

Summary

Country: Japan

Publications

  1. request reprint
    Funatsu H, Yamashita H, Shimizu E, Kojima R, Hori S. Relationship between vascular endothelial growth factor and interleukin-6 in diabetic retinopathy. Retina. 2001;21:469-77 pubmed
    ..The results of the current study suggest that there is a relationship between VEGF and IL-6 but the role of IL-6 in diabetic retinopathy is unclear and may warrant further investigation. ..
  2. request reprint
    Funatsu H, Yamashita H, Noma H, Mimura T, Yamashita T, Hori S. Increased levels of vascular endothelial growth factor and interleukin-6 in the aqueous humor of diabetics with macular edema. Am J Ophthalmol. 2002;133:70-7 pubmed
    ..618, P <.0001). These results suggest that both VEGF and IL-6 are produced together in the intraocular tissues, and are involved in the pathogenesis of macular edema. ..
  3. request reprint
    Funatsu H, Yamashita H, Ikeda T, Nakanishi Y, Kitano S, Hori S. Angiotensin II and vascular endothelial growth factor in the vitreous fluid of patients with diabetic macular edema and other retinal disorders. Am J Ophthalmol. 2002;133:537-43 pubmed
    ..We found that the levels of both AII and VEGF were elevated in the vitreous fluid of patients with hyperfluorescein DME. Our results suggest that both AII and VEGF are related to the increase of vascular permeability in DME. ..
  4. request reprint
    Funatsu H, Yamashita H, Noma H, Mochizuki H, Mimura T, Ikeda T, et al. Outcome of vitreous surgery and the balance between vascular endothelial growth factor and endostatin. Invest Ophthalmol Vis Sci. 2003;44:1042-7 pubmed
    ..Therefore, the outcome of PDR surgery can probably be predicted by measuring cytokines and/or growth factors in the vitreous fluid, with VEGF and endostatin being good candidates. ..
  5. request reprint
    Funatsu H, Yamashita H, Ikeda T, Mimura T, Eguchi S, Hori S. Vitreous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edema. Ophthalmology. 2003;110:1690-6 pubmed
    ..Interleukin-6 may possibly induce an increase of vascular permeability through a paracrine effect on VEGF in these subjects. ..
  6. request reprint
    Funatsu H, Yamashita H, Shimizu E, Mimura T, Nakamura S, Hori S. Quantitative measurement of retinal thickness in patients with diabetic macular edema is useful for evaluation of therapeutic agents. Diabetes Res Clin Pract. 2004;66:219-27 pubmed
    ..0040). Lisinopril therapy may reduce macular thickness in patients with DME, as shown by this quantitative study. In addition, quantitative measurement of retinal thickness is useful when evaluating therapeutic agents for DME. ..
  7. request reprint
    Funatsu H, Yamashita H, Sakata K, Noma H, Mimura T, Suzuki M, et al. Vitreous levels of vascular endothelial growth factor and intercellular adhesion molecule 1 are related to diabetic macular edema. Ophthalmology. 2005;112:806-16 pubmed
    ..These results suggest that VEGF and ICAM-1 are related to the increase of vascular permeability in DME patients. ..
  8. request reprint
    Funatsu H, Yamashita H, Ikeda T, Mimura T, Shimizu E, Hori S. Relation of diabetic macular edema to cytokines and posterior vitreous detachment. Am J Ophthalmol. 2003;135:321-7 pubmed
    ..To investigate whether angiotensin II (AII) or vascular endothelial growth factor (VEGF) is related to diabetic macular edema (DME) in patients with and without posterior vitreous detachment (PVD)...