Akira Yagi

Summary

Affiliation: Fukuyama University
Country: Japan

Publications

  1. ncbi Biodisposition of FITC-labeled aloemannan in mice
    A Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan
    Planta Med 67:297-300. 2001
  2. ncbi In vivo metabolism of aloemannan
    A Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Japan
    Planta Med 65:417-20. 1999
  3. ncbi Antioxidant, free radical scavenging and anti-inflammatory effects of aloesin derivatives in Aloe vera
    A Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Gakuen cho, Fukuyama, Japan
    Planta Med 68:957-60. 2002
  4. ncbi Radical scavenging glycoprotein inhibiting cyclooxygenase-2 and thromboxane A2 synthase from aloe vera gel
    A Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Gakuen cho, Fukuyama, Hiroshima, Japan
    Planta Med 69:269-71. 2003
  5. ncbi [Anti-inflammatory constituents, aloesin and aloemannan in Aloe species and effects of tanshinon VI in Salvia miltiorrhiza on heart]
    Akira Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 985 Gakuen cho, Fukuyama 729 0292, Japan
    Yakugaku Zasshi 123:517-32. 2003
  6. ncbi Monoamine oxidase inhibitors from Gentiana lutea
    Hiroyuki Haraguchi
    Faculty of Life Science and Biotechnology, Fukuyama University, Gakuen cho, Fukuyama 729 0292, Japan
    Phytochemistry 65:2255-60. 2004
  7. ncbi A flavone from Manilkara indica as a specific inhibitor against aldose reductase in vitro
    Hiroyuki Haraguchi
    Faculty of Life Science and Biotechnology, Fukuyama University, Gakuen cho, Fukuyama 729 0292, Japan
    Planta Med 69:853-5. 2003
  8. ncbi Simultaneous determination of glycyrrhizin metabolites formed by the incubation of glycyrrhizin with rat feces by semi-micro high-performance liquid chromatography
    Nobuyuki Okamura
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Gakuen cho, Hiroshima, Japan
    Biol Pharm Bull 26:658-61. 2003
  9. ncbi Effects of tanshinone VI on the hypertrophy of cardiac myocytes and fibrosis of cardiac fibroblasts of neonatal rats
    Toshiyuki Maki
    Department of Pharmacology, Tokyo University of Pharmacy and Life Science, Hachioji, Japan
    Planta Med 68:1103-7. 2002
  10. ncbi Effects of tanshinone VI on phosphorylation of ERK and Akt in isolated cardiomyocytes and cardiac fibroblasts
    Toru Arino
    Department of Molecular and Cellular Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Eur J Pharmacol 580:298-305. 2008

Detail Information

Publications10

  1. ncbi Biodisposition of FITC-labeled aloemannan in mice
    A Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan
    Planta Med 67:297-300. 2001
    ..An FITC-degraded fraction (3) with a molecular weight of 3 KD was obtained by 6-h incubation with 10% feces homogenate on Sephadex G-25 column chromatography and was shown to be a mixture of FITC-9 and 12 x hexose on TOF-MS...
  2. ncbi In vivo metabolism of aloemannan
    A Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Japan
    Planta Med 65:417-20. 1999
    ..Hydrolysis of AM showed hexosamine peaks on HPAE. The findings suggest that the immunomodulation of AM may come from not only neutral polysaccharides but also contaminated hexosamine in AM...
  3. ncbi Antioxidant, free radical scavenging and anti-inflammatory effects of aloesin derivatives in Aloe vera
    A Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Gakuen cho, Fukuyama, Japan
    Planta Med 68:957-60. 2002
    ..nicotinamide adenine dinucleotide NADPH:reduced nicotinamide adenine dinucleotide phosphate NBT:nitroblue tetrazolium Pg:prostaglandin SOD:superoxide dismutase TBA:thiobarbituric acid TCA:trichloroacetic acid XOD:xanthine oxidase..
  4. ncbi Radical scavenging glycoprotein inhibiting cyclooxygenase-2 and thromboxane A2 synthase from aloe vera gel
    A Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Gakuen cho, Fukuyama, Hiroshima, Japan
    Planta Med 69:269-71. 2003
    ..The glycoprotein fraction showed a radical scavenging activity against superoxide anion generated by the xanthine-xanthine oxidase system as well as inhibition of cyclooxygenase-2 and reduction of thromboxane A 2 synthase level in vitro...
  5. ncbi [Anti-inflammatory constituents, aloesin and aloemannan in Aloe species and effects of tanshinon VI in Salvia miltiorrhiza on heart]
    Akira Yagi
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 985 Gakuen cho, Fukuyama 729 0292, Japan
    Yakugaku Zasshi 123:517-32. 2003
    ....
  6. ncbi Monoamine oxidase inhibitors from Gentiana lutea
    Hiroyuki Haraguchi
    Faculty of Life Science and Biotechnology, Fukuyama University, Gakuen cho, Fukuyama 729 0292, Japan
    Phytochemistry 65:2255-60. 2004
    ..These compounds, and the hydrolysis product of 1, displayed competitive inhibitory properties against MAO-B which was more effective than MAO-A...
  7. ncbi A flavone from Manilkara indica as a specific inhibitor against aldose reductase in vitro
    Hiroyuki Haraguchi
    Faculty of Life Science and Biotechnology, Fukuyama University, Gakuen cho, Fukuyama 729 0292, Japan
    Planta Med 69:853-5. 2003
    ..A structure-activity relationship study revealed that the increasing number of hydroxy groups in the B-ring contributes to the increase in aldose reductase inhibition by C-glucosyl flavones...
  8. ncbi Simultaneous determination of glycyrrhizin metabolites formed by the incubation of glycyrrhizin with rat feces by semi-micro high-performance liquid chromatography
    Nobuyuki Okamura
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Gakuen cho, Hiroshima, Japan
    Biol Pharm Bull 26:658-61. 2003
    ..However, the metabolic time courses of 3-dehydroglycyrrhetic acid when incubated in aerobic conditions revealed that it apparently continued increasing during the whole incubation period...
  9. ncbi Effects of tanshinone VI on the hypertrophy of cardiac myocytes and fibrosis of cardiac fibroblasts of neonatal rats
    Toshiyuki Maki
    Department of Pharmacology, Tokyo University of Pharmacy and Life Science, Hachioji, Japan
    Planta Med 68:1103-7. 2002
    ..Abbreviations. ANP:atrial natriuretic peptide DMEM:Dulbecco-modified Eagle's medium ET-1:endothelin-1 FB-CM:fibroblast-conditioned medium FBS:fetal bovine serum IGF-1:insulin-like growth factor-1 PE:phenylephrine tsh:tanshinone VI..
  10. ncbi Effects of tanshinone VI on phosphorylation of ERK and Akt in isolated cardiomyocytes and cardiac fibroblasts
    Toru Arino
    Department of Molecular and Cellular Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Eur J Pharmacol 580:298-305. 2008
    ..These results suggest that tanshinone VI is a possible agent that can attenuate the humoral factor-induced hypertrophy of cardiomyocytes and fibrosis of cardiac fibroblasts via an attenuation of ERK phosphorylation in these cells...