Makoto Anraku

Summary

Affiliation: Fukuyama University
Country: Japan

Publications

  1. doi request reprint Antioxidant protection of human serum albumin by chitosan
    Makoto Anraku
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Sanzo 1, Gakuen cho, Fukuyama 729 0292, Japan
    Int J Biol Macromol 43:159-64. 2008
  2. doi request reprint Antioxidant effects of a dietary supplement: reduction of indices of oxidative stress in normal subjects by water-soluble chitosan
    Makoto Anraku
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 1 Sanzo, Gakuen cho, Fukuyama 729 0292, Japan
    Food Chem Toxicol 47:104-9. 2009
  3. ncbi request reprint [Surveillance study in collaboration with a university-daycare center for elderly people and nursery school for children on the use of over-the-counter drugs and health food in Fukuyama]
    Makoto Anraku
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Hiroshima, Japan
    Yakugaku Zasshi 130:1093-103. 2010
  4. ncbi request reprint The antioxidative and antilipidemic effects of different molecular weight chitosans in metabolic syndrome model rats
    Makoto Anraku
    Fukuyama University, Japan
    Biol Pharm Bull 33:1994-8. 2010
  5. doi request reprint Antioxidant properties of some different molecular weight chitosans
    Hisao Tomida
    Department of Physical Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 1 Sanzo, Gakuen cho, Fukuyama 729 0292, Japan
    Carbohydr Res 344:1690-6. 2009
  6. ncbi request reprint [Surveillance study on the needs for self-medication of local residents and community pharmacists in Fukuyama]
    Eiji Sato
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan
    Yakugaku Zasshi 131:1117-25. 2011
  7. doi request reprint Polysaccharides as potential antioxidative compounds for extended-release matrix tablets
    Hisao Tomida
    Faculty of Pharmacy and Pharmaceutical Sciences, Department of Physical Pharmaceutics, Fukuyama University, 1 Sanzo, Gakuen cho, Fukuyama 729 0292, Japan
    Carbohydr Res 345:82-6. 2010
  8. ncbi request reprint [Surveillance study on use of over-the-counter drug and health food by school pharmacist for grade-schooler, junior high school student, and high school students]
    Makoto Anraku
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan
    Yakugaku Zasshi 131:835-42. 2011
  9. ncbi request reprint Antioxidant and renoprotective activity of chitosan in nephrectomized rats
    Makoto Anraku
    Faculty of Pharmaceutical Sciences, Sojo University, 4 22 1 Ikeda, Kumamoto 860 0082, Japan Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 1 Sanzo, Gakuen cho, Fukuyama 729 0292, Japan
    Carbohydr Polym 89:302-4. 2012
  10. ncbi request reprint Comparison of receptors and enzymes regulating cholesterol levels in liver between SHR/NDmcr-cp rats and normotensive Wistar Kyoto rats at ten weeks of age
    Akihiro Michihara
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Hiroshima 729 0292, Japan
    Biol Pharm Bull 34:1116-9. 2011

Collaborators

  • Akihiro Michihara
  • Toru Maruyama
  • Eiji Sato
  • Nobuyuki Okamura
  • Hiroaki Nishio
  • Ulrich Kragh-Hansen
  • D Harada
  • Teruyuki Komatsu
  • Janusz M Gebicki
  • Kaneto Uekama
  • Masaki Otagiri
  • Yasunori Iwao
  • Hisao Tomida
  • Kenichiro Kitamura
  • Katsumi Mera
  • Keiichi Kawai
  • Yuhzo Hieda
  • Kimio Tomita
  • Keisuke Nakajou
  • Takeshi Fujii
  • Taira Yasufuku
  • Toshiya Kai
  • Daisuke Kadowaki
  • Yuka Tasaki
  • Kazuki Shimoishi
  • Mikako Hiraike
  • Shiho Wakamatsu
  • Keishi Yamasaki
  • Shen Feng Ma
  • Hidetaka Shimada
  • Tominari Choshi
  • Osamu Hori
  • Satoshi Hibino
  • Noriyuki Hatae
  • Junzo Hirose
  • Haruto Fujioka
  • Yuko Kondo
  • Nobuko Furutani
  • Kenji Akasaki
  • Eiko Fukunaga
  • Taishi Noguchi
  • Mitsuru Hashimoto
  • Kazuaki Taguchi
  • Ayaka Suenaga
  • Hiroshi Nonoguchi
  • Masataka Adachi
  • Motoko Tanaka
  • Do Gia Tuyen
  • Noriyuki Yamaotsu
  • Taku Miyoshi
  • Toshihiko Ikeda
  • Shuichi Hirono

Detail Information

Publications28

  1. doi request reprint Antioxidant protection of human serum albumin by chitosan
    Makoto Anraku
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Sanzo 1, Gakuen cho, Fukuyama 729 0292, Japan
    Int J Biol Macromol 43:159-64. 2008
    ....
  2. doi request reprint Antioxidant effects of a dietary supplement: reduction of indices of oxidative stress in normal subjects by water-soluble chitosan
    Makoto Anraku
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 1 Sanzo, Gakuen cho, Fukuyama 729 0292, Japan
    Food Chem Toxicol 47:104-9. 2009
    ..It may also inhibit oxidation of serum albumin commonly observed in patients undergoing hemodialysis, resulting in reduction of oxidative stress associated with uremia...
  3. ncbi request reprint [Surveillance study in collaboration with a university-daycare center for elderly people and nursery school for children on the use of over-the-counter drugs and health food in Fukuyama]
    Makoto Anraku
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Hiroshima, Japan
    Yakugaku Zasshi 130:1093-103. 2010
    ..The information obtained from the responses received will allow us to provide better pharmaceutical care for both children and elderly people in Fukuyama city...
  4. ncbi request reprint The antioxidative and antilipidemic effects of different molecular weight chitosans in metabolic syndrome model rats
    Makoto Anraku
    Fukuyama University, Japan
    Biol Pharm Bull 33:1994-8. 2010
    ....
  5. doi request reprint Antioxidant properties of some different molecular weight chitosans
    Hisao Tomida
    Department of Physical Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 1 Sanzo, Gakuen cho, Fukuyama 729 0292, Japan
    Carbohydr Res 344:1690-6. 2009
    ....
  6. ncbi request reprint [Surveillance study on the needs for self-medication of local residents and community pharmacists in Fukuyama]
    Eiji Sato
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan
    Yakugaku Zasshi 131:1117-25. 2011
    ....
  7. doi request reprint Polysaccharides as potential antioxidative compounds for extended-release matrix tablets
    Hisao Tomida
    Faculty of Pharmacy and Pharmaceutical Sciences, Department of Physical Pharmaceutics, Fukuyama University, 1 Sanzo, Gakuen cho, Fukuyama 729 0292, Japan
    Carbohydr Res 345:82-6. 2010
    ..These results suggest that an L-chitosan/PA complex would be potentially useful in an extended-release IPC tablet with high antioxidant activity...
  8. ncbi request reprint [Surveillance study on use of over-the-counter drug and health food by school pharmacist for grade-schooler, junior high school student, and high school students]
    Makoto Anraku
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan
    Yakugaku Zasshi 131:835-42. 2011
    ..Therefore, to provide accurate information of medicine and health food for students, the school pharmacist should engage not only in routine work but also in positive guidance about OTC drugs and health food in the future...
  9. ncbi request reprint Antioxidant and renoprotective activity of chitosan in nephrectomized rats
    Makoto Anraku
    Faculty of Pharmaceutical Sciences, Sojo University, 4 22 1 Ikeda, Kumamoto 860 0082, Japan Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 1 Sanzo, Gakuen cho, Fukuyama 729 0292, Japan
    Carbohydr Polym 89:302-4. 2012
    ....
  10. ncbi request reprint Comparison of receptors and enzymes regulating cholesterol levels in liver between SHR/NDmcr-cp rats and normotensive Wistar Kyoto rats at ten weeks of age
    Akihiro Michihara
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Hiroshima 729 0292, Japan
    Biol Pharm Bull 34:1116-9. 2011
    ..These results suggest that the serum cholesterol level in SHR-cp by the balance or regulation between the rise in cholesterol uptake and reduction in cholesterol biosynthesis in the liver is the same as that in WKY...
  11. ncbi request reprint High levels of oxidative stress exist in the brain than serum or kidneys in stroke-prone spontaneously hypertensive rats at ten weeks of age
    Akihiro Michihara
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima 729 0292, Japan
    Biol Pharm Bull 33:518-21. 2010
    ..From these results, it was suggested that levels of oxidative stress were higher in the brain than serum or kidneys of SHRSP at 10 weeks of age, but are not caused by decreases in the expression of SOD and catalase...
  12. ncbi request reprint Antioxidant effects of the highly-substituted carbazole alkaloids and their related carbazoles
    Yuhzo Hieda
    Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Hiroshima 729 0292, Japan
    Bioorg Med Chem Lett 24:3530-3. 2014
    ..The results suggest that these compounds could serve as useful clues for designing and developing novel antioxidants. ..
  13. ncbi request reprint Stabilizing mechanisms in commercial albumin preparations: octanoate and N-acetyl-L-tryptophanate protect human serum albumin against heat and oxidative stress
    Makoto Anraku
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5 1 Oe honmachi, Kumamoto 862 0973, Japan
    Biochim Biophys Acta 1702:9-17. 2004
    ..It was found that N-AcTrp, but not octanoate, has a large protecting effect on the sulfhydryl group. Thus, octanoate has the greatest stabilizing effect against heat, whereas the presence of N-AcTrp diminishes oxidation of HSA...
  14. ncbi request reprint The structure and function of oxidized albumin in hemodialysis patients: Its role in elevated oxidative stress via neutrophil burst
    Katsumi Mera
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862 0973, Japan
    Biochem Biophys Res Commun 334:1322-8. 2005
    ..In binding experiments, HD-HSA showed impaired Site II-ligand binding capabilities. Collectively, the oxidation of plasma proteins, especially HSA, might enhance oxidative stress in HD patients...
  15. ncbi request reprint An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure
    Kazuki Shimoishi
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5 1 Oe honmachi, Kumamoto, Japan
    Pharm Res 24:1283-9. 2007
    ....
  16. ncbi request reprint Intravenous iron administration induces oxidation of serum albumin in hemodialysis patients
    Makoto Anraku
    Department of Biopharmaceutics and Department of Nephrology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    Kidney Int 66:841-8. 2004
    ..Recently, plasma proteins have been demonstrated to be extremely susceptible to oxidative stress. Therefore, we investigated the effect of IVIR on the oxidative status of albumin, a major plasma protein, in HD patients...
  17. ncbi request reprint Changes of net charge and alpha-helical content affect the pharmacokinetic properties of human serum albumin
    Yasunori Iwao
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5 1 Oe honmachi, Kumamoto 862 0973, Japan
    Biochim Biophys Acta 1774:1582-90. 2007
    ..The present information should be useful when designing recombinant, therapeutical albumins or albumin products with a modified plasma half-life...
  18. ncbi request reprint Kinetic studies of covalent binding between N-acetyl-L-cysteine and human serum albumin through a mixed-disulfide using an N-methylpyridinium polymer-based column
    Daisuke Harada
    Division of Pharmacology, Drug Safety and Metabolism, Otsuka Pharmaceutical Factory, Inc, Tokushima, Japan
    Drug Metab Pharmacokinet 19:297-302. 2004
    ..The k(on,NAC) and k(off,Cys) were 0.0094 and 0.45 (h(-1)), respectively, suggesting that the pathological state may affect the binding properties of HSA and NAC...
  19. ncbi request reprint Physicochemical characterization of cross-linked human serum albumin dimer and its synthetic heme hybrid as an oxygen carrier
    Teruyuki Komatsu
    Advanced Research Institute for Science and Engineering, Waseda University, 3 4 1 Okubo, Shinjuku ku, Tokyo 169 8555, Japan
    Biochim Biophys Acta 1675:21-31. 2004
    ..The O2-binding affinity and the O2-association and -dissociation rate constants of this synthetic hemoprotein have also been evaluated...
  20. ncbi request reprint Effect of genetic variation on the thermal stability of human serum albumin
    Ulrich Kragh-Hansen
    Department of Medical Biochemistry, University of Aarhus, DK 8000 Aarhus C, Denmark
    Biochim Biophys Acta 1747:81-8. 2005
    ..The present results can be of both protein chemical relevance and of clinical interest, because they could be useful when designing stable, recombinant HSAs for clinical applications...
  21. ncbi request reprint Hydrolysis of angiotensin II receptor blocker prodrug olmesartan medoxomil by human serum albumin and identification of its catalytic active sites
    Shen Feng Ma
    Graduate School of Pharmaceutical Sciences, Kumamoto University, 5 1 Oe honmachi, Kumamoto 862 0973, Japan
    Drug Metab Dispos 33:1911-9. 2005
    ..Results obtained using a computer docking model are in agreement with the experimental results, and strongly support the hypotheses that we derived from the experiments...
  22. ncbi request reprint Oxidation of Arg-410 promotes the elimination of human serum albumin
    Yasunori Iwao
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862 0973, Japan
    Biochim Biophys Acta 1764:743-9. 2006
    ..Further, the R410A mutants had a short half-life and structure similar to oxidized HSA after oxidation. Therefore, the modification of Arg-410 via oxidative stress may promote the elimination of HSA...
  23. ncbi request reprint Oxidation and carboxy methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients
    Katsumi Mera
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    Hypertens Res 28:973-80. 2005
    ..They also indicate that diabetic complications further exacerbate the progression of oxidative stress by further increasing the amount of these modified HSA molecules...
  24. ncbi request reprint Effect of telmisartan on ambulatory blood pressure monitoring, plasma brain natriuretic peptide, and oxidative status of serum albumin in hemodialysis patients
    Hidetaka Shimada
    Department of Nephrology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    Hypertens Res 28:987-94. 2005
    ..A long-term study in a large population is required to determine the influence of telmisartan therapy on cardiovascular mortality and morbidity in HD patients...
  25. ncbi request reprint The structural and pharmacokinetic properties of oxidized human serum albumin, advanced oxidation protein products (AOPP)
    Yasunori Iwao
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Oe Honmachi, Japan
    Drug Metab Pharmacokinet 21:140-6. 2006
    ..01]; CLspleen, 2118+/-322.1 vs 32+/-2.7 microL/hr [p<0.01]). However, uptake by other organs was not significantly affected by oxidation. These results suggest that the liver and spleen play important roles in elimination of AOPP...
  26. ncbi request reprint The role of N-acetyl-methioninate as a new stabilizer for albumin products
    Makoto Anraku
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5 1 Oe honmachi, Kumamoto 862 0973, Japan
    Int J Pharm 329:19-24. 2007
    ..In the present study, we suggest that use of N-AcMet in albumin preparation is safe and free of risk of side effects...
  27. ncbi request reprint Effect of olmesartan on oxidative stress in hemodialysis patients
    Daisuke Kadowaki
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    Hypertens Res 30:395-402. 2007
    ..Olmesartan effectively lowered the extent of oxidation of albumin in both in vitro and in vivo studies, and this effect might confer benefits beyond a reduction in blood pressure...
  28. ncbi request reprint Validation of the chloramine-T induced oxidation of human serum albumin as a model for oxidative damage in vivo
    Makoto Anraku
    Faculty of Pharmaceutical Sciences, Kumamoto University, 5 1 Oe honmachi, Kumamoto 862 0973, Japan
    Pharm Res 20:684-92. 2003
    ..Important sites of oxidation were studied by mild treatment with chloramine-T and by mutating 34Cys for a serine (C34S)...