H Nakashima

Summary

Affiliation: Fukuoka University
Country: Japan

Publications

  1. pmc Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1)
    N Sugiyama
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Rheum Dis 67:1461-7. 2008
  2. pmc The efficacy of incretin therapy in patients with type 2 diabetes undergoing hemodialysis
    Yuichi Terawaki
    Department of Endocrinology and Diabetes Mellitus, School of Medicine, Fukuoka University, 7 45 1 Nanakuma, Jonan ku, Fukuoka 814 0180, Japan
    Diabetol Metab Syndr 5:10. 2013
  3. ncbi An amplification of IL-10 and TGF-beta in patients with IgG4-related tubulointerstitial nephritis
    H Nakashima
    Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
    Clin Nephrol 73:385-91. 2010
  4. pmc A case of IgG4-related tubulointerstitial nephritis concurrent with Henoch-Schönlein purpura nephritis
    Rukako Tamai
    Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University, Nanakuma7 45 1, Johnan ku, Fukuoka City, 814 0180, Japan
    Allergy Asthma Clin Immunol 7:5. 2011
  5. ncbi Absence of association between the MCP-1 gene polymorphism and histological phenotype of lupus nephritis
    H Nakashima
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Lupus 13:165-7. 2004
  6. ncbi Genetically determined interferon-gamma production influences the histological phenotype of lupus nephritis
    K Miyake
    Department of Medicine and Biosystemic Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Rheumatology (Oxford) 41:518-24. 2002
  7. ncbi Anti-monocyte chemoattractant protein-1 gene therapy attenuates nephritis in MRL/lpr mice
    S Shimizu
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    Rheumatology (Oxford) 43:1121-8. 2004
  8. ncbi Strong polarization toward Th1 immune response in ANCA-associated glomerulonephritis
    K Masutani
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
    Clin Nephrol 59:395-405. 2003
  9. ncbi Increased serum levels of circulating CD40 ligand in patients with bullous pemphigoid: preliminary results
    R Watanabe
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Dermatology 215:180-6. 2007
  10. ncbi Predominance of Th1 immune response in diffuse proliferative lupus nephritis
    K Masutani
    Kyushu University, Fukuoka, Japan
    Arthritis Rheum 44:2097-106. 2001

Collaborators

Detail Information

Publications36

  1. pmc Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1)
    N Sugiyama
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Ann Rheum Dis 67:1461-7. 2008
    ....
  2. pmc The efficacy of incretin therapy in patients with type 2 diabetes undergoing hemodialysis
    Yuichi Terawaki
    Department of Endocrinology and Diabetes Mellitus, School of Medicine, Fukuoka University, 7 45 1 Nanakuma, Jonan ku, Fukuoka 814 0180, Japan
    Diabetol Metab Syndr 5:10. 2013
    ..In this study, we examined the efficacy of incretin therapy in patients with insulin-treated type 2 diabetes undergoing hemodialysis...
  3. ncbi An amplification of IL-10 and TGF-beta in patients with IgG4-related tubulointerstitial nephritis
    H Nakashima
    Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
    Clin Nephrol 73:385-91. 2010
    ....
  4. pmc A case of IgG4-related tubulointerstitial nephritis concurrent with Henoch-Schönlein purpura nephritis
    Rukako Tamai
    Division of Nephrology and Rheumatology, Department of Internal Medicine, Faculty of Medicine, Fukuoka University, Nanakuma7 45 1, Johnan ku, Fukuoka City, 814 0180, Japan
    Allergy Asthma Clin Immunol 7:5. 2011
    ..As a result of the treatment with 30mg prednisolone, the swelling of the LNs decreased, but the patient continued to have persistent hematoproteinuria...
  5. ncbi Absence of association between the MCP-1 gene polymorphism and histological phenotype of lupus nephritis
    H Nakashima
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Lupus 13:165-7. 2004
    ..In this study we assessed the significance of the MCP-1 gene in determination of the histological phenotype in lupus nephritis. There was no association between the risk of DPGN and the MCP-1 gene genotype...
  6. ncbi Genetically determined interferon-gamma production influences the histological phenotype of lupus nephritis
    K Miyake
    Department of Medicine and Biosystemic Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Rheumatology (Oxford) 41:518-24. 2002
    ..To clarify whether the interferon-gamma (IFN-gamma) gene (IFNG) is associated with the histological phenotype of lupus nephritis...
  7. ncbi Anti-monocyte chemoattractant protein-1 gene therapy attenuates nephritis in MRL/lpr mice
    S Shimizu
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
    Rheumatology (Oxford) 43:1121-8. 2004
    ..The aim of this study was to examine whether anti-MCP-1 gene therapy inhibits the progression of nephritis in MRL/lpr mice...
  8. ncbi Strong polarization toward Th1 immune response in ANCA-associated glomerulonephritis
    K Masutani
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
    Clin Nephrol 59:395-405. 2003
    ....
  9. ncbi Increased serum levels of circulating CD40 ligand in patients with bullous pemphigoid: preliminary results
    R Watanabe
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Dermatology 215:180-6. 2007
    ..CD40L circulates in soluble form, and some reports suggest that serum soluble CD40L (sCD40L) levels are increased in various autoimmune diseases...
  10. ncbi Predominance of Th1 immune response in diffuse proliferative lupus nephritis
    K Masutani
    Kyushu University, Fukuoka, Japan
    Arthritis Rheum 44:2097-106. 2001
    ..In patients with lupus nephritis, the peripheral blood Th1:Th2 ratio could be useful as a parameter that reflects the renal histologic activity or the strength of the local Thl response...
  11. ncbi Two polymorphisms within interleukin-3 (hIL3) gene detected by mismatch PCR/RFLP
    H Nakashima
    Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Genes Immun 1:156-8. 1999
    ..We clarified that these substitutions were frequent polymorphisms in the Japanese population by using the mismatch-PCR (polymerase chain reaction)/RFLP (restriction fragment length polymorphism) method...
  12. ncbi The combination of polymorphisms within interferon-gamma receptor 1 and receptor 2 associated with the risk of systemic lupus erythematosus
    H Nakashima
    First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    FEBS Lett 453:187-90. 1999
    ..The greatest risk of the development of SLE was detected in the individuals who had the combination of IFNGR1 Met14/Val14 genotype and IFNGR2 Gln64/Gln64 genotype...
  13. ncbi Monocyte chemoattractant protein-1 activates a regional Th1 immunoresponse in nephritis of MRL/lpr mice
    S Shimizu
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Clin Exp Rheumatol 23:239-42. 2005
    ..The aim of this study was to clarify whether blockade of the MCP-1 signal by anti-MCP-1 gene therapy influences the Th1/Th2 balance in MRL/lpr mice...
  14. doi A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome: immunological analysis of B cells, T cells and cytokines
    Y Tamimoto
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Rheumatology (Oxford) 47:821-7. 2008
    ..We performed a dose-escalation study for treatment of Japanese patients with autoimmune diseases including eight with SLE and one with Evans' syndrome...
  15. ncbi Tacrolimus is effective for lupus nephritis patients with persistent proteinuria
    A Uchino
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, and Department of Internal Medicine, Fukuoka University Hospital, Fukuoka, Japan
    Clin Exp Rheumatol 28:6-12. 2010
    ..To evaluate the safety and potential efficacy of tacrolimus for the treatment of patients with lupus nephritis and persistent proteinuria...
  16. ncbi Proliferative activity of cancer cells in front and center areas of carcinoma in situ and invasive sites of esophageal squamous-cell carcinoma
    H Kuwano
    Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Int J Cancer 78:149-52. 1998
    ..These results therefore support the concept of field carcinogenesis...
  17. ncbi Serum chemokine profiles in patients with alopecia areata
    Y Kuwano
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Br J Dermatol 157:466-73. 2007
    ..Although chemokines play an important role in various inflammatory diseases, there have been few studies about the role of chemokines in alopecia areata (AA)...
  18. ncbi Association of polymorphism in the NeuroD/BETA2 gene with type 1 diabetes in the Japanese
    I Iwata
    First Department of Internal Medicine, Kyushu University, Fukuoka, Japan
    Diabetes 48:416-9. 1999
    ..006). Because the variant of the NeuroD/BETA2 gene (Ala45Thr) is associated with type 1 but not type 2 diabetes, it may be implicated in the loss of pancreatic beta-cells in type 1 diabetes...
  19. ncbi Reduced expression of manganese superoxide dismutase mRNA may correlate with invasiveness in esophageal carcinoma
    Y Toh
    Department of Gastroenterologic Surgery, National Kyushu Cancer Center, Fukuoka, Japan
    Oncology 59:223-8. 2000
    ....
  20. ncbi Factors associated with anxiety, depression and suicide ideation in female outpatients with SLE in Japan
    R Ishikura
    Department of Neuropsychiatry, Graduate School of Medical Science, Kyushu University, Fukuoka City, Fukuoka Ken, Japan
    Clin Rheumatol 20:394-400. 2001
    ....
  21. doi T cell-specific overexpression of interleukin-27 receptor α subunit (WSX-1) prevents spontaneous skin inflammation in MRL/lpr mice
    M Kido
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Br J Dermatol 164:1214-20. 2011
    ....
  22. pmc Severity-based treatment for Japanese patients with MPO-ANCA-associated vasculitis: the JMAAV study
    Shoichi Ozaki
    Division of Rheumatology, Department of Internal Medicine, St Marianna University School of Medicine, 2 16 1 Sugao, Miyamae ku, Kawasaki 216 8511, Japan
    Mod Rheumatol 22:394-404. 2012
    ..The regimen employed in this trial was tailor-made based on patients' disease severity and disease type, and it seems that standardization can be consistent with treatment choices made according to severity...
  23. ncbi Single oral administration of pilsicainide versus infusion of disopyramide for termination of paroxysmal atrial fibrillation: a multicenter trial
    K Kumagai
    Department of Cardiology, Fukuoka University School of Medicine, 7 45 1, Nanakuma, Jonan ku, Fukuoka, 814 0180 Japan
    Pacing Clin Electrophysiol 23:1880-2. 2000
    ..In conclusion, a single oral dose of PLS was as effective as an infusion of DISO to restore sinus rhythm in patients with recent-onset AF. PLS consistently terminated AF regardless of its time of onset...
  24. ncbi Treatment of mixed atrial fibrillation and typical atrial flutter by hybrid catheter ablation
    K Kumagai
    Department of Cardiology, Fukuoka University School of Medicine, 7 45 1, Nanakuma, Jonan ku, Fukuoka, 814 0180 Japan
    Pacing Clin Electrophysiol 23:1839-42. 2000
    ..These findings suggest that isthmus ablation combined with PV focal ablation may be effective in mixed AF and typical atrial flutter...
  25. ncbi Role of rapid focal activation in the maintenance of atrial fibrillation originating from the pulmonary veins
    K Kumagai
    Department of Cardiology, Fukuoka University School of Medicine, 7 45 1, Nanakuma, Jonan ku, Fukuoka, 814 0180 Japan
    Pacing Clin Electrophysiol 23:1823-7. 2000
    ..A PV interaction, a RFA triggering another, may be involved in the maintenance of AF. RFA arising from PVs is important not only as a trigger of onset, but also in the maintenance of AF...
  26. ncbi Increased serum levels of a proliferation-inducing ligand in patients with bullous pemphigoid
    R Watanabe
    Department of Dermatology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo, Tokyo 113 8655, Japan
    J Dermatol Sci 46:53-60. 2007
    ..Although the functions of APRIL have not been fully evaluated, recent studies suggest that circulating levels of APRIL are increased in various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis...
  27. ncbi Angiotensin II antagonist prevents electrical remodeling in atrial fibrillation
    H Nakashima
    Second Department of Internal Medicine, School of Medicine, Fukuoka University, Fukuoka, Japan
    Circulation 101:2612-7. 2000
    ..The purpose of this study was to investigate the effects of candesartan and captopril on atrial electrical remodeling...
  28. ncbi Association between IL-4 genotype and IL-4 production in the Japanese population
    H Nakashima
    Department of Medicine and Biosystemic Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
    Genes Immun 3:107-9. 2002
    ..These results make it likely that IL-4 genotype could influence the type of immune response...
  29. ncbi Development of rheumatoid arthritis following autologous peripheral blood stem cell transplantation
    R Imamura
    Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
    Bone Marrow Transplant 30:527-9. 2002
    ..However, the patient developed RA 40 days after transplantation. Our experience suggests that the systemic autoimmune disease, RA, may occur in patients with predisposing factors after autologous PBSCT...
  30. doi Video-assisted thoracic surgery for lung cancer in hemodialysis patients
    T Obuchi
    Department of Thoracic Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
    Asian J Endosc Surg 4:157-60. 2011
    ..At the same time, the use of video-assisted thoracic surgery (VATS) for lung cancer has also increased. However, reports of the outcome of VATS in hemodialysis patients are still quite rare...
  31. ncbi Drug-induced hypersensitivity syndrome associated with transient hypogammaglobulinaemia and increase in serum IgE level
    H Nakashima
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Dermatology 210:349-52. 2005
    ..In addition, serum levels of interferon gamma, interleukin (IL)-4 and soluble IL-2 receptor, which were increased in the early phase of the disease, decreased gradually after the corticosteroid therapy...
  32. ncbi Pathogenesis of esophageal squamous cell carcinoma with lymphoid stroma
    H Kuwano
    Department of Surgery I, Faculty of Medicine, Gunma University, 3-39-22, Showa-machi, Maebashi 371-8511, Japan
    Hepatogastroenterology 48:458-61. 2001
    ....
  33. ncbi New technique for simultaneous catheter mapping of pulmonary veins for catheter ablation in focal atrial fibrillation
    K Kumagai
    Department of Cardiology, Fukuoka University School of Medicine, Fukuoka, Japan
    Cardiology 94:233-8. 2000
    ..The purpose of the present study was to investigate the efficacy of using four mapping catheters in four PVs simultaneously in the ablation of focal AF...
  34. ncbi Genes from nine genomes are separated into their organisms in the dinucleotide composition space
    H Nakashima
    School of Health Sciences, Faculty of Medicine, Kanazawa University, Japan
    DNA Res 5:251-9. 1998
    ..Thus, the distinct feature observed in the dinucleotide composition may reflect the phylogenetic relationship of organisms...
  35. ncbi Supraventricular tachycardia in a patient with Lown-Ganong-Levine syndrome associated with apical hypertrophic cardiomyopathy
    M Hayano
    Department of Internal Medicine, Saga Medical School, Japan
    Jpn Heart J 29:249-56. 1988
    ..To our knowledge, a case of Lown-Ganong-Levine syndrome with apical hypertrophic cardiomyopathy has not been previously described in the literature...
  36. ncbi Comparison of transthoracic Doppler echocardiography and natriuretic peptides in predicting mean pulmonary capillary wedge pressure in patients with chronic atrial fibrillation
    K Matsukida
    First Department of Internal Medicine, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima City, 890-8520, Japan
    J Am Soc Echocardiogr 14:1080-7. 2001
    ....