Hiroshi Toyama

Summary

Affiliation: Fujita Health University
Country: Japan

Publications

  1. ncbi In vivo imaging of microglial activation using a peripheral benzodiazepine receptor ligand: [11C]PK-11195 and animal PET following ethanol injury in rat striatum
    Hiroshi Toyama
    Department of Radiology, Fujita Health University, 1 98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Ann Nucl Med 22:417-24. 2008
  2. ncbi Characterization of neuronal damage by iomazenil binding and cerebral blood flow in an ischemic rat model
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Aichi, Japan
    Ann Nucl Med 12:267-73. 1998
  3. ncbi PET imaging of brain with the beta-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer's disease
    Hiroshi Toyama
    Department of Radiology, Fujita Health University, 1 98, Dengakugakubo, Kutsukake, Toyoake, 470 1192, Aichi, Japan
    Eur J Nucl Med Mol Imaging 32:593-600. 2005
  4. ncbi Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography
    Hiroshi Toyama
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    J Nucl Med 45:1398-405. 2004
  5. ncbi Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PET
    Hiroshi Toyama
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Nucl Med Biol 31:251-6. 2004
  6. ncbi Simple and low-cost tele-nuclear medicine conference system with the e-mail protocol
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Japan
    Ann Nucl Med 15:465-70. 2001
  7. ncbi Evaluation of asialoglycoprotein receptor imaging agent as a marker of hepatic ischemia-reperfusion injury and recovery
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Aichi, Japan
    Ann Nucl Med 13:155-60. 1999
  8. ncbi (123)I-BMIPP and (99m)Tc-TF discordance on myocardial scintigraphy and it's correlation with functional recovery following acute myocardial infarction: role of conventional echocardiography
    Shankar K Biswas
    Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470 1192, Japan
    Int J Cardiovasc Imaging 25:765-75. 2009
  9. ncbi The washout rate of (123)I-BMIPP and the evolution of left ventricular function in patients with successfully reperfused ST-segment elevation myocardial infarction: comparisons with the echocardiography
    Shankar K Biswas
    Department of Cardiology, Fujita Health UniversityHospital, Dengakugakubo, Kutsukake, Toyoake, Aichi, Japan
    Int J Cardiovasc Imaging 26:155-64. 2010
  10. ncbi Role of ¹²³I-BMIPP and serum B-type natriuretic peptide for the evaluation of patients with heart failure
    Shankar Kumar Biswas
    Department of Cardiology, Fujita Health University Hospital, 1 98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Singapore Med J 53:398-402. 2012

Detail Information

Publications23

  1. ncbi In vivo imaging of microglial activation using a peripheral benzodiazepine receptor ligand: [11C]PK-11195 and animal PET following ethanol injury in rat striatum
    Hiroshi Toyama
    Department of Radiology, Fujita Health University, 1 98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Ann Nucl Med 22:417-24. 2008
    ..To investigate whether [(11)C]PK-11195, a specific peripheral benzodiazepine receptors (PBRs) ligand for positron emission tomography (PET), can show activated microglia in a rat brain injury model...
  2. ncbi Characterization of neuronal damage by iomazenil binding and cerebral blood flow in an ischemic rat model
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Aichi, Japan
    Ann Nucl Med 12:267-73. 1998
    ..Iomazenil correlated well with the neuron distribution and the finding of a discrepancy between iomazenil and IMP might be useful in evaluating the neuronal damage...
  3. ncbi PET imaging of brain with the beta-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer's disease
    Hiroshi Toyama
    Department of Radiology, Fujita Health University, 1 98, Dengakugakubo, Kutsukake, Toyoake, 470 1192, Aichi, Japan
    Eur J Nucl Med Mol Imaging 32:593-600. 2005
    ..The purpose of this study was to evaluate the capacity of [11C]6-OH-BTA-1 and positron emission tomography (PET) to quantify beta-amyloid (Abeta) plaques in the Tg2576 mouse model of Alzheimer's disease (AD)...
  4. ncbi Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography
    Hiroshi Toyama
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    J Nucl Med 45:1398-405. 2004
    ..In addition, we compared the rCMR(glc) values under isoflurane, ketamine and xylazine anesthesia, and awake states...
  5. ncbi Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PET
    Hiroshi Toyama
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Nucl Med Biol 31:251-6. 2004
    ..Results suggest that anesthesia impedes FDG uptake in mouse brain and affects FDG uptake in heart; however, the effects in the brain and heart differ depending on the type of anesthesia used...
  6. ncbi Simple and low-cost tele-nuclear medicine conference system with the e-mail protocol
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Japan
    Ann Nucl Med 15:465-70. 2001
    ..We developed a tele-nuclear medicine conference system with electronic mail (e-mail) on the Internet...
  7. ncbi Evaluation of asialoglycoprotein receptor imaging agent as a marker of hepatic ischemia-reperfusion injury and recovery
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Aichi, Japan
    Ann Nucl Med 13:155-60. 1999
    ..ASGP-R binding may provide valuable information on ischemia-reperfusion injury and recovery...
  8. ncbi (123)I-BMIPP and (99m)Tc-TF discordance on myocardial scintigraphy and it's correlation with functional recovery following acute myocardial infarction: role of conventional echocardiography
    Shankar K Biswas
    Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470 1192, Japan
    Int J Cardiovasc Imaging 25:765-75. 2009
    ..44, P = 0.004). Mismatched defect score could predict the approximate amount of viable dysfunctional myocardium, and the degree of mismatch showed a significant correlation with the improvement of both systolic and diastolic function...
  9. ncbi The washout rate of (123)I-BMIPP and the evolution of left ventricular function in patients with successfully reperfused ST-segment elevation myocardial infarction: comparisons with the echocardiography
    Shankar K Biswas
    Department of Cardiology, Fujita Health UniversityHospital, Dengakugakubo, Kutsukake, Toyoake, Aichi, Japan
    Int J Cardiovasc Imaging 26:155-64. 2010
    ..We proved that the WR of the BMIPP is a promising indicator of improvement of the LV wall motion (WMSI) following ST-segment elevation myocardial infarction and successful reperfusion...
  10. ncbi Role of ¹²³I-BMIPP and serum B-type natriuretic peptide for the evaluation of patients with heart failure
    Shankar Kumar Biswas
    Department of Cardiology, Fujita Health University Hospital, 1 98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Singapore Med J 53:398-402. 2012
    ..This study aimed to evaluate the usefulness of ¹²³I-BMIPP imaging and serum BNP levels in patients with heart failure (HF)...
  11. ncbi Two activated stages of microglia and PET imaging of peripheral benzodiazepine receptors with [(11)C]PK11195 in rats
    Fumitaka Ito
    Department of Radiology, Fujita Health University, Kutsukake, Toyoake, Aichi, Japan
    Ann Nucl Med 24:163-9. 2010
    ..We evaluated whether [(11)C]PK11195 PET can indicate differences of microglial activation between no treatment and lipopolysaccharide (LPS) treatment in a rat artificial injury model of brain inflammation...
  12. ncbi Synthesis and evaluation of two 18F-labeled 6-iodo-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridine derivatives as prospective radioligands for beta-amyloid in Alzheimer's disease
    Lisheng Cai
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, Maryland 20892, USA
    J Med Chem 47:2208-18. 2004
    ....
  13. ncbi Linearized reference tissue parametric imaging methods: application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain
    Masanori Ichise
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Cereb Blood Flow Metab 23:1096-112. 2003
    ..MRTM2 allowed rapid generation of parametric images with the noise reductions consistent with the simulations. Rapid parametric imaging by MRTM2 should be a useful method for human [11C]DASB positron emission tomography studies...
  14. ncbi Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease
    José A Rodríguez-Gómez
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, Porter Neuroscience Research Center, National Institute of Health, Bethesda, Maryland 20892, USA
    Stem Cells 25:918-28. 2007
    ..This work supports continued interest in ES cells as a source of functional DA neurons...
  15. ncbi Evaluation of 2 scatter correction methods using a striatal phantom for quantitative brain SPECT
    Douglass C Vines
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 0135, USA
    J Nucl Med Technol 31:157-60. 2003
    ..The first is based on thresholding the energy spectrum (ES), and the second is based on a modification of the transmission-dependent convolution subtraction (TDCS) method...
  16. ncbi Discrepancy between myocardial perfusion and fatty acid metabolism following acute myocardial infarction for evaluating the dysfunctional viable myocardium
    Shankar K Biswas
    Research Fellow, Department of Radiology, Fujita Health University Hospital 1 98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Indian Heart J 64:16-22. 2012
    ..This study was designed to evaluate the degree of discrepancy between BMIPP and TF at the subacute state of AMI...
  17. ncbi Relationship between radiation pneumonitis and organizing pneumonia after radiotherapy for breast cancer
    Yumi Oie
    Department of Radiology, Fujita Health University School of Medicine, 1 98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Radiat Oncol 8:56. 2013
    ..The goal of this study was to evaluate the relationship between RP and OP after irradiation for breast cancer...
  18. ncbi Nuclear medicine practice in Japan: a report of the sixth nationwide survey in 2007
    Yasuo Kuwabara
    Department of Radiology, Fukuoka University Hospital, 7 45 1 Nanakuma, Johnan ku, Fukuoka 814 0180, Japan
    Ann Nucl Med 23:209-15. 2009
    ..The Subcommittee on the Survey of Nuclear Medicine Practice in Japan has performed a nationwide survey of nuclear medicine practice every 5 years since 1982 to provide detailed information on its present status...
  19. ncbi Sentinel lymph node navigation surgery in Paget's disease of the vulva
    Gen Kudo
    Department of Radiology, Fujita Health University, School of Medicine, Kutsukake, Toyoake, Japan
    Clin Nucl Med 27:909-10. 2002
  20. ncbi Whole-brain perfusion CT performed with a prototype 256-detector row CT system: initial experience
    Kazuhiro Murayama
    Department of Radiology, Faculty of Radiological Technology, School of Health Sciences, Fujita Health University, Toyoake, Aichi 470 1192, Japan
    Radiology 250:202-11. 2009
    ....
  21. ncbi Evaluation of probable or possible dementia with lewy bodies using 123I-IMP brain perfusion SPECT, 123I-MIBG, and 99mTc-MIBI myocardial SPECT
    Yoshitaka Inui
    Department of Radiology, Fujita Health University, Toyoake, Japan
    J Nucl Med 48:1641-50. 2007
    ....
  22. ncbi Fatty acid metabolism and myocardial perfusion imaging for the evaluation of global left ventricular dysfunction following acute myocardial infarction: comparisons with echocardiography
    Shankar Kumar Biswas
    Dept of Cardiology, Fujita Health University School of Medicine, 1 98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Int J Cardiol 138:290-9. 2010
    ..This study was designed for the first time to assess systolic, diastolic and global LV dysfunction considering BMIPP and TF mismatched defect score (MMDS), and comparing this approach with the conventional Doppler echocardiography...
  23. ncbi Strategies to improve neuroreceptor parameter estimation by linear regression analysis
    Masanori Ichise
    Molecular Imaging Branch, National Institutes of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Cereb Blood Flow Metab 22:1271-81. 2002
    ..For tracers with slow kinetics and low to moderate noise, however, MA2 may provide the lowest bias while maintaining computational ease for pixelwise parameter estimation...