Hiroshi Toyama

Summary

Affiliation: Fujita Health University
Country: Japan

Publications

  1. doi request reprint In vivo imaging of microglial activation using a peripheral benzodiazepine receptor ligand: [11C]PK-11195 and animal PET following ethanol injury in rat striatum
    Hiroshi Toyama
    Department of Radiology, Fujita Health University, 1 98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Ann Nucl Med 22:417-24. 2008
  2. ncbi request reprint Characterization of neuronal damage by iomazenil binding and cerebral blood flow in an ischemic rat model
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Aichi, Japan
    Ann Nucl Med 12:267-73. 1998
  3. ncbi request reprint Evaluation of asialoglycoprotein receptor imaging agent as a marker of hepatic ischemia-reperfusion injury and recovery
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Aichi, Japan
    Ann Nucl Med 13:155-60. 1999
  4. ncbi request reprint Simple and low-cost tele-nuclear medicine conference system with the e-mail protocol
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Japan
    Ann Nucl Med 15:465-70. 2001
  5. ncbi request reprint PET imaging of brain with the beta-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer's disease
    Hiroshi Toyama
    Department of Radiology, Fujita Health University, 1 98, Dengakugakubo, Kutsukake, Toyoake, 470 1192, Aichi, Japan
    Eur J Nucl Med Mol Imaging 32:593-600. 2005
  6. ncbi request reprint Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography
    Hiroshi Toyama
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    J Nucl Med 45:1398-405. 2004
  7. ncbi request reprint Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PET
    Hiroshi Toyama
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Nucl Med Biol 31:251-6. 2004
  8. doi request reprint (123)I-BMIPP and (99m)Tc-TF discordance on myocardial scintigraphy and it's correlation with functional recovery following acute myocardial infarction: role of conventional echocardiography
    Shankar K Biswas
    Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470 1192, Japan
    Int J Cardiovasc Imaging 25:765-75. 2009
  9. doi request reprint The washout rate of (123)I-BMIPP and the evolution of left ventricular function in patients with successfully reperfused ST-segment elevation myocardial infarction: comparisons with the echocardiography
    Shankar K Biswas
    Department of Cardiology, Fujita Health UniversityHospital, Dengakugakubo, Kutsukake, Toyoake, Aichi, Japan
    Int J Cardiovasc Imaging 26:155-64. 2010
  10. pmc Discrepancy between myocardial perfusion and fatty acid metabolism following acute myocardial infarction for evaluating the dysfunctional viable myocardium
    Shankar K Biswas
    Department of Radiology, Fujita Health University Hospital, Dengakugakubo, Kutsukake, Toyoake, Aichi, Japan
    Indian Heart J 64:16-22. 2012

Detail Information

Publications25

  1. doi request reprint In vivo imaging of microglial activation using a peripheral benzodiazepine receptor ligand: [11C]PK-11195 and animal PET following ethanol injury in rat striatum
    Hiroshi Toyama
    Department of Radiology, Fujita Health University, 1 98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Ann Nucl Med 22:417-24. 2008
    ..To investigate whether [(11)C]PK-11195, a specific peripheral benzodiazepine receptors (PBRs) ligand for positron emission tomography (PET), can show activated microglia in a rat brain injury model...
  2. ncbi request reprint Characterization of neuronal damage by iomazenil binding and cerebral blood flow in an ischemic rat model
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Aichi, Japan
    Ann Nucl Med 12:267-73. 1998
    ..Iomazenil correlated well with the neuron distribution and the finding of a discrepancy between iomazenil and IMP might be useful in evaluating the neuronal damage...
  3. ncbi request reprint Evaluation of asialoglycoprotein receptor imaging agent as a marker of hepatic ischemia-reperfusion injury and recovery
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Aichi, Japan
    Ann Nucl Med 13:155-60. 1999
    ..ASGP-R binding may provide valuable information on ischemia-reperfusion injury and recovery...
  4. ncbi request reprint Simple and low-cost tele-nuclear medicine conference system with the e-mail protocol
    H Toyama
    Department of Radiology, Fujita Health University, Toyoake, Japan
    Ann Nucl Med 15:465-70. 2001
    ..We developed a tele-nuclear medicine conference system with electronic mail (e-mail) on the Internet...
  5. ncbi request reprint PET imaging of brain with the beta-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer's disease
    Hiroshi Toyama
    Department of Radiology, Fujita Health University, 1 98, Dengakugakubo, Kutsukake, Toyoake, 470 1192, Aichi, Japan
    Eur J Nucl Med Mol Imaging 32:593-600. 2005
    ..The purpose of this study was to evaluate the capacity of [11C]6-OH-BTA-1 and positron emission tomography (PET) to quantify beta-amyloid (Abeta) plaques in the Tg2576 mouse model of Alzheimer's disease (AD)...
  6. ncbi request reprint Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography
    Hiroshi Toyama
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    J Nucl Med 45:1398-405. 2004
    ..In addition, we compared the rCMR(glc) values under isoflurane, ketamine and xylazine anesthesia, and awake states...
  7. ncbi request reprint Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PET
    Hiroshi Toyama
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Nucl Med Biol 31:251-6. 2004
    ..Results suggest that anesthesia impedes FDG uptake in mouse brain and affects FDG uptake in heart; however, the effects in the brain and heart differ depending on the type of anesthesia used...
  8. doi request reprint (123)I-BMIPP and (99m)Tc-TF discordance on myocardial scintigraphy and it's correlation with functional recovery following acute myocardial infarction: role of conventional echocardiography
    Shankar K Biswas
    Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470 1192, Japan
    Int J Cardiovasc Imaging 25:765-75. 2009
    ..44, P = 0.004). Mismatched defect score could predict the approximate amount of viable dysfunctional myocardium, and the degree of mismatch showed a significant correlation with the improvement of both systolic and diastolic function...
  9. doi request reprint The washout rate of (123)I-BMIPP and the evolution of left ventricular function in patients with successfully reperfused ST-segment elevation myocardial infarction: comparisons with the echocardiography
    Shankar K Biswas
    Department of Cardiology, Fujita Health UniversityHospital, Dengakugakubo, Kutsukake, Toyoake, Aichi, Japan
    Int J Cardiovasc Imaging 26:155-64. 2010
    ..We proved that the WR of the BMIPP is a promising indicator of improvement of the LV wall motion (WMSI) following ST-segment elevation myocardial infarction and successful reperfusion...
  10. pmc Discrepancy between myocardial perfusion and fatty acid metabolism following acute myocardial infarction for evaluating the dysfunctional viable myocardium
    Shankar K Biswas
    Department of Radiology, Fujita Health University Hospital, Dengakugakubo, Kutsukake, Toyoake, Aichi, Japan
    Indian Heart J 64:16-22. 2012
    ..This study was designed to evaluate the degree of discrepancy between BMIPP and TF at the subacute state of AMI...
  11. ncbi request reprint Role of ¹²³I-BMIPP and serum B-type natriuretic peptide for the evaluation of patients with heart failure
    Shankar Kumar Biswas
    Department of Cardiology, Fujita Health University Hospital, 1 98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Singapore Med J 53:398-402. 2012
    ..This study aimed to evaluate the usefulness of ¹²³I-BMIPP imaging and serum BNP levels in patients with heart failure (HF)...
  12. doi request reprint Two activated stages of microglia and PET imaging of peripheral benzodiazepine receptors with [(11)C]PK11195 in rats
    Fumitaka Ito
    Department of Radiology, Fujita Health University, Kutsukake, Toyoake, Aichi, Japan
    Ann Nucl Med 24:163-9. 2010
    ..We evaluated whether [(11)C]PK11195 PET can indicate differences of microglial activation between no treatment and lipopolysaccharide (LPS) treatment in a rat artificial injury model of brain inflammation...
  13. ncbi request reprint Linearized reference tissue parametric imaging methods: application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain
    Masanori Ichise
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Cereb Blood Flow Metab 23:1096-112. 2003
    ..MRTM2 allowed rapid generation of parametric images with the noise reductions consistent with the simulations. Rapid parametric imaging by MRTM2 should be a useful method for human [11C]DASB positron emission tomography studies...
  14. ncbi request reprint Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease
    José A Rodríguez-Gómez
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, Porter Neuroscience Research Center, National Institute of Health, Bethesda, Maryland 20892, USA
    Stem Cells 25:918-28. 2007
    ..This work supports continued interest in ES cells as a source of functional DA neurons...
  15. ncbi request reprint Synthesis and evaluation of two 18F-labeled 6-iodo-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridine derivatives as prospective radioligands for beta-amyloid in Alzheimer's disease
    Lisheng Cai
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, Bethesda, Maryland 20892, USA
    J Med Chem 47:2208-18. 2004
    ....
  16. ncbi request reprint Evaluation of 2 scatter correction methods using a striatal phantom for quantitative brain SPECT
    Douglass C Vines
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 0135, USA
    J Nucl Med Technol 31:157-60. 2003
    ..The first is based on thresholding the energy spectrum (ES), and the second is based on a modification of the transmission-dependent convolution subtraction (TDCS) method...
  17. pmc Relationship between radiation pneumonitis and organizing pneumonia after radiotherapy for breast cancer
    Yumi Oie
    Department of Radiology, Fujita Health University School of Medicine, 1 98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Radiat Oncol 8:56. 2013
    ..The goal of this study was to evaluate the relationship between RP and OP after irradiation for breast cancer...
  18. doi request reprint Nuclear medicine practice in Japan: a report of the sixth nationwide survey in 2007
    Yasuo Kuwabara
    Department of Radiology, Fukuoka University Hospital, 7 45 1 Nanakuma, Johnan ku, Fukuoka 814 0180, Japan
    Ann Nucl Med 23:209-15. 2009
    ..The Subcommittee on the Survey of Nuclear Medicine Practice in Japan has performed a nationwide survey of nuclear medicine practice every 5 years since 1982 to provide detailed information on its present status...
  19. doi request reprint Whole-brain perfusion CT performed with a prototype 256-detector row CT system: initial experience
    Kazuhiro Murayama
    Department of Radiology, Faculty of Radiological Technology, School of Health Sciences, Fujita Health University, Toyoake, Aichi 470 1192, Japan
    Radiology 250:202-11. 2009
    ....
  20. ncbi request reprint Evaluation of probable or possible dementia with lewy bodies using 123I-IMP brain perfusion SPECT, 123I-MIBG, and 99mTc-MIBI myocardial SPECT
    Yoshitaka Inui
    Department of Radiology, Fujita Health University, Toyoake, Japan
    J Nucl Med 48:1641-50. 2007
    ....
  21. doi request reprint (89)Sr bremsstrahlung single photon emission computed tomography using a gamma camera for bone metastases
    Seiichiro Ota
    Department of Radiology, Fujita Health University School of Medicine, 1 98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470 1192, Japan
    Ann Nucl Med 28:112-9. 2014
    ..Strontium-89 chloride ((89)Sr) bremsstrahlung single photon emission computed tomography (SPECT) imaging was evaluated for detecting more detailed whole body (89)Sr distribution...
  22. ncbi request reprint Sentinel lymph node navigation surgery in Paget's disease of the vulva
    Gen Kudo
    Department of Radiology, Fujita Health University, School of Medicine, Kutsukake, Toyoake, Japan
    Clin Nucl Med 27:909-10. 2002
  23. doi request reprint Fatty acid metabolism and myocardial perfusion imaging for the evaluation of global left ventricular dysfunction following acute myocardial infarction: comparisons with echocardiography
    Shankar Kumar Biswas
    Dept of Cardiology, Fujita Health University School of Medicine, 1 98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Int J Cardiol 138:290-9. 2010
    ..This study was designed for the first time to assess systolic, diastolic and global LV dysfunction considering BMIPP and TF mismatched defect score (MMDS), and comparing this approach with the conventional Doppler echocardiography...
  24. ncbi request reprint Strategies to improve neuroreceptor parameter estimation by linear regression analysis
    Masanori Ichise
    Molecular Imaging Branch, National Institutes of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Cereb Blood Flow Metab 22:1271-81. 2002
    ..For tracers with slow kinetics and low to moderate noise, however, MA2 may provide the lowest bias while maintaining computational ease for pixelwise parameter estimation...
  25. doi request reprint Incidental detection of rupture of substitute urinary bladder on bone scan
    Kazuhiro Yamanouchi
    Department of Radiology, Fujita Health University, Aichi, Japan
    Clin Nucl Med 38:543-5. 2013
    ..The radionuclides used in bone scans accumulate in the bone and are excreted in the urine. Incidental detection of rupture of a substitute urinary bladder may lead to appropriate intermediate neobladder repair...