Takeo Fujita

Summary

Country: Japan

Publications

  1. ncbi request reprint Rectal adenocarcinoma metastatic to the thyroid gland
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama, 700 8558, Japan
    Int J Clin Oncol 9:515-9. 2004
  2. ncbi request reprint Proteasome inhibitor bortezomib increases PTEN expression and enhances trastuzumab-induced growth inhibition in trastuzumab-resistant cells
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Anticancer Drugs 17:455-62. 2006
  3. pmc PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancer
    T Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, 700 8558 Okayama, Japan
    Br J Cancer 94:247-52. 2006
  4. doi request reprint Clinicopathological relevance of UbcH10 in breast cancer
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, 2 5 1 Shikata cho, Okayama, Japan
    Cancer Sci 100:238-48. 2009
  5. doi request reprint Bilateral angiosarcoma of the breast detected by magnetic resonance imaging during pregnancy
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, 2 5 1 Shikata, Okayama 700 8558, Japan
    Int J Clin Oncol 14:560-3. 2009
  6. ncbi request reprint Paraneoplastic hypercalcemia with adenosquamous carcinoma of the colon
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama 700 8558, Japan
    Int J Clin Oncol 10:144-7. 2005
  7. pmc Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, Okayama, Japan
    BMC Cancer 9:87. 2009
  8. ncbi request reprint Proteasome inhibitors can alter the signaling pathways and attenuate the P-glycoprotein-mediated multidrug resistance
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Japan
    Int J Cancer 117:670-82. 2005
  9. ncbi request reprint Tumor inhibitory effect of gefitinib (ZD1839, Iressa) and taxane combination therapy in EGFR-overexpressing breast cancer cell lines (MCF7/ADR, MDA-MB-231)
    Daisuke Takabatake
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Shikata, Okayama, Japan
    Int J Cancer 120:181-8. 2007
  10. ncbi request reprint Antitumor effects and drug interactions of the proteasome inhibitor bortezomib (PS341) in gastric cancer cells
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, Okayama, Japan
    Anticancer Drugs 18:677-86. 2007

Detail Information

Publications19

  1. ncbi request reprint Rectal adenocarcinoma metastatic to the thyroid gland
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama, 700 8558, Japan
    Int J Clin Oncol 9:515-9. 2004
    ..Thyroid metastasis from colon and rectal carcinoma is rare, with only 11 cases appearing in the literature since 1990. The rarity and prognosis of thyroid metastasis from colon carcinoma are discussed here...
  2. ncbi request reprint Proteasome inhibitor bortezomib increases PTEN expression and enhances trastuzumab-induced growth inhibition in trastuzumab-resistant cells
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Anticancer Drugs 17:455-62. 2006
    ..The proteasome inhibitor PS341 could increase the level of PTEN and inhibit the downstream pathway of ErbB2, interfering with phosphorylation of Akt...
  3. pmc PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancer
    T Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, 700 8558 Okayama, Japan
    Br J Cancer 94:247-52. 2006
    ..PTEN activity might play an important and major role in its HER2/PI3K/Akt-mediated antitumour effect, and could be a useful biomarker for predicting the efficacy of trastuzumab in the treatment of breast cancer...
  4. doi request reprint Clinicopathological relevance of UbcH10 in breast cancer
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, 2 5 1 Shikata cho, Okayama, Japan
    Cancer Sci 100:238-48. 2009
    ..Thus, aberrant UbcH10 activity may induce the dysfunction of proper cell cycle progression and result in the aggressive behavior of tumor cells in patients with breast cancer...
  5. doi request reprint Bilateral angiosarcoma of the breast detected by magnetic resonance imaging during pregnancy
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, 2 5 1 Shikata, Okayama 700 8558, Japan
    Int J Clin Oncol 14:560-3. 2009
    ..Diagnosed as angiosarcoma preoperatively, excision of the bilateral tumors was performed. Histological findings of the removed bilateral tumors were compatible with high-grade angiosarcoma of the breast...
  6. ncbi request reprint Paraneoplastic hypercalcemia with adenosquamous carcinoma of the colon
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama 700 8558, Japan
    Int J Clin Oncol 10:144-7. 2005
    ..The histopathologic diagnosis was poorly differentiated adenosquamous carcinoma. The patient died due to tumor recurrence 4 months after the second surgery...
  7. pmc Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, Okayama, Japan
    BMC Cancer 9:87. 2009
    ..To assess the potential role of UbcH10 in colon cancer progression, we analyzed the clinicopathological relevance of UbcH10 in colon cancer...
  8. ncbi request reprint Proteasome inhibitors can alter the signaling pathways and attenuate the P-glycoprotein-mediated multidrug resistance
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Japan
    Int J Cancer 117:670-82. 2005
    ..And influence with MAPK pathways, which have been reported to be associated with the regulation of P-gp, might be contributed to the resensitization brought by proteasome inhibitors...
  9. ncbi request reprint Tumor inhibitory effect of gefitinib (ZD1839, Iressa) and taxane combination therapy in EGFR-overexpressing breast cancer cell lines (MCF7/ADR, MDA-MB-231)
    Daisuke Takabatake
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Shikata, Okayama, Japan
    Int J Cancer 120:181-8. 2007
    ..These results suggest gefitinib overcomes the drug-resistance of these cells, thereby increasing the effects of taxane on MCF7/ADR cells. Further, activation of the EGFR-Akt pathway by taxane is related to this synergistic effect...
  10. ncbi request reprint Antitumor effects and drug interactions of the proteasome inhibitor bortezomib (PS341) in gastric cancer cells
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, Okayama, Japan
    Anticancer Drugs 18:677-86. 2007
    ..Our results demonstrate that bortezomib could be an effective antitumor agent in the treatment of gastric cancer, both as single-agent therapy and in combination with conventional chemotherapeutic agents...
  11. ncbi request reprint Clinical significance of multidetector-row computed tomography in breast surgery
    Hiroyoshi Doihara
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, Okayama City, Japan
    Breast J 12:S204-9. 2006
    ..Moreover, MDCT can provide appropriate information for the determination of adequate surgical margins and contribute to increases in breast conservation rates...
  12. pmc The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells
    Hirokuni Ikeda
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama City, Okayama, Japan
    Breast Cancer Res 12:R43. 2010
    ..In this study, we examined the correlation of MAPT expression with the sensitivity of human breast cancer cells to taxanes, and the relationship between ER and MAPT...
  13. ncbi request reprint Multidetector row computed tomography for diagnosing intraductal extension of breast carcinoma
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama City, Japan
    J Surg Oncol 91:10-6. 2005
    ..The present study evaluated the clinical utility of MD-CT for detecting intraductal extension of breast carcinoma, and analyzed clinical parameters affecting the detection of intraductal extension under MD-CT...
  14. ncbi request reprint Long-term survival of a patient with advanced adenosquamous carcinoma of the gallbladder after radical resection
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama City, 700 8558, Japan
    J Hepatobiliary Pancreat Surg 12:147-50. 2005
    ..Gallbladder carcinoma was diagnosed, and radical resection, including partial gastrectomy, was performed. Histopathologically, adenosquamous carcinoma was diagnosed, and it was graded as si, hinf0, binf0, pv0, a0, t4, n0, and stage IVa...
  15. ncbi request reprint Anaplastic thyroid carcinoma associated with granulocyte colony-stimulating factor: report of a case
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Surg Today 36:63-7. 2006
    ..As a result, her general condition deteriorated rapidly and the patient died 2 weeks after the onset of leukocytosis...
  16. ncbi request reprint [Significance of multidetector row computed tomography in breast surgery]
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine
    Nihon Rinsho 65:353-6. 2007
  17. doi request reprint Solitary cranial metastasis of thyroid carcinoma 13 years after primary surgery: report of a case
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, 2 5 1 Shikata cho, Okayama, 700 8558, Japan
    Surg Today 39:44-7. 2009
    ..Thus, the patient underwent completion thyroidectomy followed by internal radiotherapy. She has remained well in the 4 years since her operation, without any signs of further recurrence...
  18. ncbi request reprint Intraoperative prediction of compensatory sweating for thoracic sympathectomy
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Jpn J Thorac Cardiovasc Surg 53:481-5. 2005
    ..The present study investigated whether intraoperative palmar temperature and blood flow are useful for assessing PCS after ETS...
  19. ncbi request reprint Utility of vessel-sealing systems in thyroid surgery
    Takeo Fujita
    Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700 8558, Japan
    Acta Med Okayama 60:93-8. 2006
    ..However, further evaluation is warranted to adequately determine the relative merits of the VSS compared to conventional handtie methods...