Research Topics
Species | Takeo FujitaSummaryCountry: Japan Publications
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Publications
Rectal adenocarcinoma metastatic to the thyroid glandTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama, 700 8558, Japan
Int J Clin Oncol 9:515-9. 2004..Thyroid metastasis from colon and rectal carcinoma is rare, with only 11 cases appearing in the literature since 1990. The rarity and prognosis of thyroid metastasis from colon carcinoma are discussed here...- Proteasome inhibitor bortezomib increases PTEN expression and enhances trastuzumab-induced growth inhibition in trastuzumab-resistant cellsTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
Anticancer Drugs 17:455-62. 2006..The proteasome inhibitor PS341 could increase the level of PTEN and inhibit the downstream pathway of ErbB2, interfering with phosphorylation of Akt... - PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancerT Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, 700 8558 Okayama, Japan
Br J Cancer 94:247-52. 2006..PTEN activity might play an important and major role in its HER2/PI3K/Akt-mediated antitumour effect, and could be a useful biomarker for predicting the efficacy of trastuzumab in the treatment of breast cancer... - Clinicopathological relevance of UbcH10 in breast cancerTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, 2 5 1 Shikata cho, Okayama, Japan
Cancer Sci 100:238-48. 2009..Thus, aberrant UbcH10 activity may induce the dysfunction of proper cell cycle progression and result in the aggressive behavior of tumor cells in patients with breast cancer... - Bilateral angiosarcoma of the breast detected by magnetic resonance imaging during pregnancyTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, 2 5 1 Shikata, Okayama 700 8558, Japan
Int J Clin Oncol 14:560-3. 2009..Diagnosed as angiosarcoma preoperatively, excision of the bilateral tumors was performed. Histological findings of the removed bilateral tumors were compatible with high-grade angiosarcoma of the breast... - Paraneoplastic hypercalcemia with adenosquamous carcinoma of the colonTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama 700 8558, Japan
Int J Clin Oncol 10:144-7. 2005..The histopathologic diagnosis was poorly differentiated adenosquamous carcinoma. The patient died due to tumor recurrence 4 months after the second surgery... - Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancerTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, Okayama, Japan
BMC Cancer 9:87. 2009..To assess the potential role of UbcH10 in colon cancer progression, we analyzed the clinicopathological relevance of UbcH10 in colon cancer... - Proteasome inhibitors can alter the signaling pathways and attenuate the P-glycoprotein-mediated multidrug resistanceTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Japan
Int J Cancer 117:670-82. 2005..And influence with MAPK pathways, which have been reported to be associated with the regulation of P-gp, might be contributed to the resensitization brought by proteasome inhibitors... - Tumor inhibitory effect of gefitinib (ZD1839, Iressa) and taxane combination therapy in EGFR-overexpressing breast cancer cell lines (MCF7/ADR, MDA-MB-231)Daisuke Takabatake
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Shikata, Okayama, Japan
Int J Cancer 120:181-8. 2007..These results suggest gefitinib overcomes the drug-resistance of these cells, thereby increasing the effects of taxane on MCF7/ADR cells. Further, activation of the EGFR-Akt pathway by taxane is related to this synergistic effect... - Antitumor effects and drug interactions of the proteasome inhibitor bortezomib (PS341) in gastric cancer cellsTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, Okayama, Japan
Anticancer Drugs 18:677-86. 2007..Our results demonstrate that bortezomib could be an effective antitumor agent in the treatment of gastric cancer, both as single-agent therapy and in combination with conventional chemotherapeutic agents... - Clinical significance of multidetector-row computed tomography in breast surgeryHiroyoshi Doihara
Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, Okayama City, Japan
Breast J 12:S204-9. 2006..Moreover, MDCT can provide appropriate information for the determination of adequate surgical margins and contribute to increases in breast conservation rates... - The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cellsHirokuni Ikeda
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama City, Okayama, Japan
Breast Cancer Res 12:R43. 2010..In this study, we examined the correlation of MAPT expression with the sensitivity of human breast cancer cells to taxanes, and the relationship between ER and MAPT... - Multidetector row computed tomography for diagnosing intraductal extension of breast carcinomaTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama-city, Japan
J Surg Oncol 91:10-6. 2005.... - Long-term survival of a patient with advanced adenosquamous carcinoma of the gallbladder after radical resectionTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama-city, 700-8558, Japan
J Hepatobiliary Pancreat Surg 12:147-50. 2005..Gallbladder carcinoma was diagnosed, and radical resection, including partial gastrectomy, was performed. Histopathologically, adenosquamous carcinoma was diagnosed, and it was graded as si, hinf0, binf0, pv0, a0, t4, n0, and stage IVa... - Anaplastic thyroid carcinoma associated with granulocyte colony-stimulating factor: report of a caseTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8558, Japan
Surg Today 36:63-7. 2006..As a result, her general condition deteriorated rapidly and the patient died 2 weeks after the onset of leukocytosis... - [Significance of multidetector row computed tomography in breast surgery]Takeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University School of Medicine
Nippon Rinsho 65:353-6. 2007 - Solitary cranial metastasis of thyroid carcinoma 13 years after primary surgery: report of a caseTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University School of Medicine, 2 5 1 Shikata cho, Okayama, 700 8558, Japan
Surg Today 39:44-7. 2009..Thus, the patient underwent completion thyroidectomy followed by internal radiotherapy. She has remained well in the 4 years since her operation, without any signs of further recurrence... - Intraoperative prediction of compensatory sweating for thoracic sympathectomyTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
Jpn J Thorac Cardiovasc Surg 53:481-5. 2005..05) and blood flow (p<0.05). CONCLUSION: Intraoperative monitoring of increases in palmar temperature and blood flow may be useful in patients with primary hyperhidrosis, to predict the range of PCS after ETS... - Utility of vessel-sealing systems in thyroid surgeryTakeo Fujita
Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Acta Med Okayama 60:93-8. 2006..However, further evaluation is warranted to adequately determine the relative merits of the VSS compared to conventional handtie methods...