Koji Ohira,

Summary

Affiliation: Fujita Health University
Country: Japan

Publications

  1. doi request reprint Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal nets in gamma-aminobutyric acidergic interneurons of the frontal cortex in adult mice
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake 470 1192, Japan
    Mol Brain 6:43. 2013
  2. pmc Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, 470 1192, Japan
    Mol Brain 6:12. 2013
  3. pmc Fluoxetine-induced cortical adult neurogenesis
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Japan
    Neuropsychopharmacology 38:909-20. 2013
  4. pmc Chronic treatment with fluoxetine for more than 6 weeks decreases neurogenesis in the subventricular zone of adult mice
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Japan
    Mol Brain 4:10. 2011
  5. pmc Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders
    Nobuyuki Yamasaki
    Frontier Technology Center, Kyoto University Graduate School of Medicine, Japan
    Mol Brain 1:6. 2008
  6. pmc Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake 470 1192, Japan
    Mol Brain 3:26. 2010
  7. doi request reprint Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, Japan
    Nat Neurosci 13:173-9. 2010
  8. doi request reprint Injury-induced neurogenesis in the mammalian forebrain
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470 1192, Japan
    Cell Mol Life Sci 68:1645-56. 2011
  9. pmc Expression of the AMPA Receptor Subunits GluR1 and GluR2 is Associated with Granule Cell Maturation in the Dentate Gyrus
    Hideo Hagihara
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University Toyoake, Japan
    Front Neurosci 5:100. 2011

Collaborators

Detail Information

Publications9

  1. doi request reprint Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal nets in gamma-aminobutyric acidergic interneurons of the frontal cortex in adult mice
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake 470 1192, Japan
    Mol Brain 6:43. 2013
    ..Thus, in this study, we used immunohistological analysis to assess the effect of FLX treatment on GABAergic interneurons in the medial frontal cortex (mFC) and reticular thalamic nucleus (RTN)...
  2. pmc Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, 470 1192, Japan
    Mol Brain 6:12. 2013
    ..However, the molecular and cellular mechanisms underlying the abnormalities in this mutant remain unknown...
  3. pmc Fluoxetine-induced cortical adult neurogenesis
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Japan
    Neuropsychopharmacology 38:909-20. 2013
    ..Our findings indicate that FLX stimulates the neurogenesis of cortical GABAergic interneurons, which might have, at least, some functions, including a suppressive effect on apoptosis induced by ischemia...
  4. pmc Chronic treatment with fluoxetine for more than 6 weeks decreases neurogenesis in the subventricular zone of adult mice
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Japan
    Mol Brain 4:10. 2011
    ..Since almost all of those studies treated animals with drugs for 2 to 4 weeks as chronic treatment models of antidepressants, it is possible that antidepressant treatments for longer periods would affect adult neurogenesis in the SVZ...
  5. pmc Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders
    Nobuyuki Yamasaki
    Frontier Technology Center, Kyoto University Graduate School of Medicine, Japan
    Mol Brain 1:6. 2008
    ..Based on these results, we propose that an "immature DG" in adulthood might induce alterations in behavior and serve as a promising candidate endophenotype of schizophrenia and other human psychiatric disorders...
  6. pmc Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake 470 1192, Japan
    Mol Brain 3:26. 2010
    ..These findings indicate that TDO might be required at a late-stage of granule cell development, such as during axonal and dendritic growth, synaptogenesis and its maturation...
  7. doi request reprint Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, Japan
    Nat Neurosci 13:173-9. 2010
    ..Our results suggest that layer 1 NPCs are a source of adult neurogenesis under ischemic conditions...
  8. doi request reprint Injury-induced neurogenesis in the mammalian forebrain
    Koji Ohira
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470 1192, Japan
    Cell Mol Life Sci 68:1645-56. 2011
    ..This review focuses on brain insult-induced neurogenesis in the mammalian forebrain, especially in the neocortex...
  9. pmc Expression of the AMPA Receptor Subunits GluR1 and GluR2 is Associated with Granule Cell Maturation in the Dentate Gyrus
    Hideo Hagihara
    Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University Toyoake, Japan
    Front Neurosci 5:100. 2011
    ..Taken together, these findings indicate that GluR1 and GluR2 expression closely correlates with the neuronal maturation state, and that GluR1 and GluR2 are useful markers for mature granule cells in the dentate gyrus...