Haruki Nishizawa

Summary

Affiliation: Fujita Health University
Country: Japan

Publications

  1. ncbi request reprint The etiological role of allogeneic fetal rejection in pre-eclampsia
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan
    Am J Reprod Immunol 58:11-20. 2007
  2. doi request reprint Mouse model for allogeneic immune reaction against fetus recapitulates human pre-eclampsia
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    J Obstet Gynaecol Res 34:1-6. 2008
  3. doi request reprint Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, 1 98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Mol Hum Reprod 14:595-602. 2008
  4. ncbi request reprint Analysis of nitric oxide metabolism as a placental or maternal factor underlying the etiology of pre-eclampsia
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University, Toyoake, Japan
    Gynecol Obstet Invest 68:239-47. 2009
  5. pmc Comparative gene expression profiling of placentas from patients with severe pre-eclampsia and unexplained fetal growth restriction
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Fujita Health University, Toyoake, Japan
    Reprod Biol Endocrinol 9:107. 2011
  6. doi request reprint Impact of indoleamine 2,3-dioxygenase on the antioxidant system in the placentas of severely pre-eclamptic patients
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Syst Biol Reprod Med 57:174-8. 2011
  7. doi request reprint Genetic variation in the indoleamine 2,3-dioxygenase gene in pre-eclampsia
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Am J Reprod Immunol 64:68-76. 2010
  8. ncbi request reprint Decreased expression of apelin in placentas from severe pre-eclampsia patients
    Hiromi Inuzuka
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Toyoake, Japan
    Hypertens Pregnancy 32:410-21. 2013
  9. pmc Age-related decrease of meiotic cohesins in human oocytes
    Makiko Tsutsumi
    Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, Japan
    PLoS ONE 9:e96710. 2014
  10. doi request reprint Polymorphisms in the annexin A5 gene promoter in Japanese women with recurrent pregnancy loss
    Hironori Miyamura
    Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192, Japan
    Mol Hum Reprod 17:447-52. 2011

Collaborators

Detail Information

Publications14

  1. ncbi request reprint The etiological role of allogeneic fetal rejection in pre-eclampsia
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan
    Am J Reprod Immunol 58:11-20. 2007
    ..It has been demonstrated that allogeneic fetal rejection in normal pregnancy is prevented by placental indoleamine 2,3-dioxygenase (IDO). Further, an immunological etiology has been implicated in pre-eclampsia...
  2. doi request reprint Mouse model for allogeneic immune reaction against fetus recapitulates human pre-eclampsia
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    J Obstet Gynaecol Res 34:1-6. 2008
    ..From this observation, we hypothesized that induction of maternal allogeneic immune reaction by reduced IDO activity is one of the causes of pre-eclampsia...
  3. doi request reprint Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, 1 98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470 1192, Japan
    Mol Hum Reprod 14:595-602. 2008
    ..These data might imply that PAPP-A2 may be up-regulated in pre-eclamptic pregnancy to compensate for IGFBP5-mediated suppression of the IGF pathway, although final birthweights are still low in pre-eclamptic pregnancy...
  4. ncbi request reprint Analysis of nitric oxide metabolism as a placental or maternal factor underlying the etiology of pre-eclampsia
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University, Toyoake, Japan
    Gynecol Obstet Invest 68:239-47. 2009
    ..Defective nitric oxide (NO)-mediated vasodilation is widely regarded as an underlying cause of hypertension in pre-eclampsia, although there are also arguments against this hypothesis...
  5. pmc Comparative gene expression profiling of placentas from patients with severe pre-eclampsia and unexplained fetal growth restriction
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Fujita Health University, Toyoake, Japan
    Reprod Biol Endocrinol 9:107. 2011
    ..The aim of this study was to further investigate the mechanisms underlying pre-eclampsia and unexplained FGR...
  6. doi request reprint Impact of indoleamine 2,3-dioxygenase on the antioxidant system in the placentas of severely pre-eclamptic patients
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Syst Biol Reprod Med 57:174-8. 2011
    ..These results show that oxidative stress is associated with decreased IDO activity in the pre-eclamptic placenta and suggest an impact of low IDO activity other than immune modulation in promoting the onset of this disorder...
  7. doi request reprint Genetic variation in the indoleamine 2,3-dioxygenase gene in pre-eclampsia
    Haruki Nishizawa
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    Am J Reprod Immunol 64:68-76. 2010
    ..To investigate the contribution of genomic variations in the indoleamine 2,3-dioxygenase (IDO) gene to the onset of pre-eclampsia...
  8. ncbi request reprint Decreased expression of apelin in placentas from severe pre-eclampsia patients
    Hiromi Inuzuka
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Toyoake, Japan
    Hypertens Pregnancy 32:410-21. 2013
    ..Apelin is a small peptide that may potentially act as an angiogenic factor. The expression of apelin was examined at the RNA and protein levels in this study...
  9. pmc Age-related decrease of meiotic cohesins in human oocytes
    Makiko Tsutsumi
    Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, Japan
    PLoS ONE 9:e96710. 2014
    ....
  10. doi request reprint Polymorphisms in the annexin A5 gene promoter in Japanese women with recurrent pregnancy loss
    Hironori Miyamura
    Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192, Japan
    Mol Hum Reprod 17:447-52. 2011
    ..Our data indicate that SNP5 is a novel risk factor for this disease in the Japanese population...
  11. doi request reprint CD9 gene variations are not associated with female infertility in humans
    Sachie Nishiyama
    Division of Molecular Genetics, Institute for Comprehensive Medical Science, Toyoake, Japan
    Gynecol Obstet Invest 69:116-21. 2010
    ..To determine whether genetic alterations in the CD9 gene are associated with female infertility in humans...
  12. doi request reprint Spontaneous spinal epidural hematoma during pregnancy: three case reports
    Shin Tada
    Department of Obstetrics and Gynecology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
    J Obstet Gynaecol Res 37:1734-8. 2011
    ..Pregnancy-induced structural changes of the vascular walls and hemodynamic changes may play a role in the pathogenesis of spontaneous spinal epidural hematoma...
  13. doi request reprint Bilateral interruption of mid-fallopian tubes and ovarian anomalies including ectopic ovary and cystic teratoma, a previously unreported combination
    Sachie Nishiyama
    Department of Obstetrics and Gynecology, Fujita Health University, Toyoake, Aichi, Japan
    J Minim Invasive Gynecol 17:534-7. 2010
    ..The complex of these anomalies is rare. A fundamental error might have existed in the mesenchyme of the gonadal ridges of the early embryo, rather than the epithelial origin of the müllerian and wolffian ducts...
  14. pmc Mutations of the SYCP3 gene in women with recurrent pregnancy loss
    Hasbaira Bolor
    Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi 470 1192, Japan
    Am J Hum Genet 84:14-20. 2009
    ..Combined with the fact that similar mutations have been previously identified in two males with azoospermia, our current data suggest that sexual dimorphism in response to meiotic disruption occurs even in humans...