Affiliation: Fujita Health University
- Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout miceKoichi Tanda
Genetic Engineering and Functional Genomics Group, Horizontal Medical Research Organization, Kyoto University Graduate School of Medicine, Kyoto, Japan
Mol Brain 2:19. 2009..We also examined the role of nNOS in dopamine/DARPP-32 signaling in striatal slices from nNOS KO mice and the effects of the administration of a dopamine D1 receptor agonist on behavior in nNOS KO mice...
- Spine-type-specific recruitment of newly synthesized AMPA receptors with learningNaoki Matsuo
Department of Cell Biology and Institute for Childhood and Neglected Diseases, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Science 319:1104-7. 2008..Our results are consistent with a "synaptic tagging" model to allow activated synapses to subsequently capture newly synthesized receptor and also demonstrate a critical functional distinction in the mushroom spines with learning...
- Localization of a stable neural correlate of associative memoryLeon G Reijmers
Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA
Science 317:1230-3. 2007..The ability to manipulate these neurons genetically should allow a more precise dissection of the molecular mechanisms of memory encoding within a distributed neuronal network...
- Roles of STEF/Tiam1, guanine nucleotide exchange factors for Rac1, in regulation of growth cone morphologyNaoki Matsuo
Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
Mol Cell Neurosci 24:69-81. 2003..These data are used to propose a model that extracellular and intracellular information is integrated by STEF/Tiam1 to modulate the balance of Rho GTPase activities in the growth cone and, consequently, to control growth cone behavior...