Research Topics
| Fusao KawaiSummaryAffiliation: Fujita Health University Country: Japan Publications
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Detail Information
Publications
Odorants suppress voltage-gated currents in retinal horizontal cells in goldfishF Kawai
Department of Physiology, School of Medicine, Fujita Health University, 1 98 Dengakugakubo, Kutsukakechou, Toyoake, Aichi, Japan
Neurosci Lett 281:151-4. 2000..This suggests that odorants may suppress the voltage-gated currents in retinal horizontal cells by the same mechanism described in olfactory receptor cells...
[Ion channels and action potentials in olfactory receptor cells]Fusao Kawai
Department of Physiology, School of Medicine, Fujita Health University, Toyoake, Japan
Nihon Shinkei Seishin Yakurigaku Zasshi 27:201-5. 2007..This review discusses current knowledge concerning the mechanisms of spike generation in ORCs. It also reviews how neurotransmitters and hormones modulate ionic currents and action potentials in ORCs...
Suppression by an h current of spontaneous Na+ action potentials in human cone and rod photoreceptorsFusao Kawai
Department of Physiology, School of Medicine, Fujita Health University, Aichi, Japan
Invest Ophthalmol Vis Sci 46:390-7. 2005..The sense of vision in humans is robust, and visual flickering is rarely experienced. To investigate this mechanism, electrophysiological and molecular biological techniques were used on human cone and rod photoreceptors...
cGMP modulates spike responses of retinal ganglion cells via a cGMP-gated currentFusao Kawa
Department of Neuroscience, University of Pennsylvania, Philadelphia, USA
Vis Neurosci 19:373-80. 2002..Modulation of this channel via the long-range NO-synthase amacrine cell may contribute to control of contrast gain by peripheral mechanisms...
Modulation by hyperpolarization-activated cationic currents of voltage responses in human rodsFusao Kawai
Department of Physiology, Fujita Health University, 1 98 Dengakugakubo, Kutsukakechou, Toyoake, Aichi, Japan
Brain Res 943:48-55. 2002..We suggest that I(h) becomes activated in the course of large hyperpolarizations generated by bright-light illumination and may modify the waveform of the photovoltage in human rods...
Ca2+-activated K+ currents regulate odor adaptation by modulating spike encoding of olfactory receptor cellsFusao Kawai
Department of Physiology, Fujita Health University, Toyoake, Aichi, 470 1192, Japan
Biophys J 82:2005-15. 2002..I conclude that not only the ciliary machinery but also the somatic membrane currents are crucial to odor adaptation...
Na(+) action potentials in human photoreceptorsF Kawai
Department of Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi 470 1192, Japan
Neuron 30:451-8. 2001..This served to amplify the release of a neurotransmitter when a bright light is turned off, and thus selectively amplify the off response to the light signal...
Enhancement by T-type Ca2+ currents of odor sensitivity in olfactory receptor cellsF Kawai
Department of Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi, 470 1192, Japan
J Neurosci 21:RC144. 2001..We conclude that I(Ca,T) contributes to enhance odor sensitivity by lowering the threshold of spike generation in ORCs...
Modulation by cGMP of the voltage-gated currents in newt olfactory receptor cellsF Kawai
Department of Physiology, School of Medicine, Fujita Health University, 1 98 Dengakugakubo, Kutsukakechou, Toyoake, Aichi, 470 1192, Japan
Neurosci Res 39:327-37. 2001..We suggest that cGMP may lower the threshold in olfactory perception by decreasing the current threshold to generate spikes, and also prevent the saturation of odor signals by increasing the maximum spike frequency...
Direct suppression by odorants of cyclic nucleotide-gated currents in the newt photoreceptorsF Kawai
Department of Physiology, School of Medicine, Fujita Health University, 1 98 Dengakugakubo, Kutsukakechou, Toyoake, 470 1192, Aichi, Japan
Brain Res 876:180-4. 2000..This suggests that odorants suppress the CNG currents directly rather than via the second messenger system in photoreceptors, and also likely in olfactory receptor cells...
Dopamine modulates the voltage response of human rod photoreceptors by inhibiting the h currentFusao Kawai
Department of Physiology, School of Medicine, Fujita Health University, Aichi, Japan
Invest Ophthalmol Vis Sci 52:4113-7. 2011..The purpose of this study was to determine how dopamine modulates I(h) in human rods and regulates voltage responses...
Patch-clamp recording of human retinal photoreceptors and bipolar cellsMahito Ohkuma
Department of Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan
Photochem Photobiol 83:317-22. 2007..Sodium channels may serve to amplify the release of a neurotransmitter and to accelerate the light-dark change in photosignals...
Spike encoding of olfactory receptor cellsKenji Narusuye
Department of Physiology, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukakechou, Toyoake, Aichi 470-1192, Japan
Neurosci Res 46:407-13. 2003..This review discusses current knowledge concerning the mechanisms of spike generation in ORCs. It also reviews how neurotransmitters and hormones modulate ionic currents and action potentials in ORCs...
