Yoshinori Ito

Summary

Affiliation: Fujita Health University
Country: Japan

Publications

  1. ncbi request reprint Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population
    Y Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192, Japan
    Cancer Lett 163:171-8. 2001
  2. ncbi request reprint Colorectal cancer and serum C-reactive protein levels: a case-control study nested in the JACC Study
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Toyoake City, Japan
    J Epidemiol 15:S185-9. 2005
  3. ncbi request reprint Cancer mortality and serum levels of carotenoids, retinol, and tocopherol: a population-based follow-up study of inhabitants of a rural area of Japan
    Yoshinori Ito
    Department of Environmental Health, Fujita Health University School of Health Sciences, Toyoake City, Aichi Prefecture, 470 1192, Japan
    Asian Pac J Cancer Prev 6:10-5. 2005
  4. ncbi request reprint Serum carotenoids and mortality from lung cancer: a case-control study nested in the Japan Collaborative Cohort (JACC) study
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192
    Cancer Sci 94:57-63. 2003
  5. pmc The effect of serum carotenoids on atrophic gastritis among the inhabitants of a rural area in Hokkaido, Japan
    Y Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Dengakugakubo, Kutsukake cho, 470 1192, Toyoake City, Aichi Prefecture, Japan
    Environ Health Prev Med 6:184-8. 2001
  6. ncbi request reprint Serum antioxidants and subsequent mortality rates of all causes or cancer among rural Japanese inhabitants
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Toyoake, Japan
    Int J Vitam Nutr Res 72:237-50. 2002
  7. doi request reprint Variations in serum transforming growth factor-beta1 levels with gender, age and lifestyle factors of healthy Japanese adults
    Yingsong Lin
    Department of Public Health, Aichi Medical University School of Medicine, Nagakute, Japan
    Dis Markers 27:23-8. 2009
  8. ncbi request reprint Serum insulin-like growth factors I and II, insulin-like growth factor binding protein-3 and risk of breast cancer in the Japan Collaborative Cohort study
    Fumio Sakauchi
    Department of Public Health, Sapporo Medical University School of Medicine, Japan
    Asian Pac J Cancer Prev 10:51-5. 2009
  9. ncbi request reprint Lung cancer mortality and serum levels of carotenoids, retinol, tocopherols, and folic acid in men and women: a case-control study nested in the JACC Study
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Japan
    J Epidemiol 15:S140-9. 2005
  10. ncbi request reprint Lack of association between risk of biliary tract cancer and circulating IGF (Insulin-like Growth Factor) -I, IGF-II or IGFBP-3 (IGF-binding Protein-3): A nested case-control study in a large scale cohort study in Japan
    Kiyoko Yagyu
    Department of Public Health, Aichi Medical University School of Medicine, Japan
    Asian Pac J Cancer Prev 10:63-7. 2009

Collaborators

Detail Information

Publications82

  1. ncbi request reprint Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population
    Y Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192, Japan
    Cancer Lett 163:171-8. 2001
    ..20 (95% C.I.: 1.10-4.39) and 0.34 (95% C.I.: 0.17-0.68), respectively. The above results suggested that GLA plays a role in reducing the incidence of AG, whereas DHA may increase a risk of AG...
  2. ncbi request reprint Colorectal cancer and serum C-reactive protein levels: a case-control study nested in the JACC Study
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Toyoake City, Japan
    J Epidemiol 15:S185-9. 2005
    ..We investigated whether serum levels of C-reactive protein (CRP), a biomarker of inflammation, are associated with colorectal cancer, using serum samples collected in the Japan Collaborative Cohort Study (JACC Study)...
  3. ncbi request reprint Cancer mortality and serum levels of carotenoids, retinol, and tocopherol: a population-based follow-up study of inhabitants of a rural area of Japan
    Yoshinori Ito
    Department of Environmental Health, Fujita Health University School of Health Sciences, Toyoake City, Aichi Prefecture, 470 1192, Japan
    Asian Pac J Cancer Prev 6:10-5. 2005
    ..High intake of green-yellow vegetables contributing to serum levels of alpha- and beta- carotenes, as well as lycopene, may reduce the risk of cancer mortality, especially from colorectal cancer, in rural Japanese...
  4. ncbi request reprint Serum carotenoids and mortality from lung cancer: a case-control study nested in the Japan Collaborative Cohort (JACC) study
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192
    Cancer Sci 94:57-63. 2003
    ..the lowest quartile was 0.39 (95% CI, 0.19-0.79). Higher serum levels of carotenoids such as alpha- and beta-carotenes may play a role in preventing death from lung cancer among Japanese...
  5. pmc The effect of serum carotenoids on atrophic gastritis among the inhabitants of a rural area in Hokkaido, Japan
    Y Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Dengakugakubo, Kutsukake cho, 470 1192, Toyoake City, Aichi Prefecture, Japan
    Environ Health Prev Med 6:184-8. 2001
    ..These results suggest that frequent intake of foods ric, in carotenoids with provitamin A activity may reduce the risk of AG...
  6. ncbi request reprint Serum antioxidants and subsequent mortality rates of all causes or cancer among rural Japanese inhabitants
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Toyoake, Japan
    Int J Vitam Nutr Res 72:237-50. 2002
    ..However, high serum levels of tocopherols and retinol did not demonstrate clear associations with either low mortality rates from all causes or cancer of all sites...
  7. doi request reprint Variations in serum transforming growth factor-beta1 levels with gender, age and lifestyle factors of healthy Japanese adults
    Yingsong Lin
    Department of Public Health, Aichi Medical University School of Medicine, Nagakute, Japan
    Dis Markers 27:23-8. 2009
    ..0001). These findings suggest that serum TGF-beta1 levels appear to be modulated by {gender}, age and lifestyle factors such as obesity, cigarette smoking, and alcohol drinking in healthy Japanese adults...
  8. ncbi request reprint Serum insulin-like growth factors I and II, insulin-like growth factor binding protein-3 and risk of breast cancer in the Japan Collaborative Cohort study
    Fumio Sakauchi
    Department of Public Health, Sapporo Medical University School of Medicine, Japan
    Asian Pac J Cancer Prev 10:51-5. 2009
    ..47), which was likely to be inversely associated with the risk. In postmenopausal women, IGFBP-3 showed a marginal dose-dependent association with the risk (trend P= 0.06). Further studies are needed to confirm these findings...
  9. ncbi request reprint Lung cancer mortality and serum levels of carotenoids, retinol, tocopherols, and folic acid in men and women: a case-control study nested in the JACC Study
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Japan
    J Epidemiol 15:S140-9. 2005
    ..To examine the association by sex, we extended the follow-up and analyzed additional serum samples...
  10. ncbi request reprint Lack of association between risk of biliary tract cancer and circulating IGF (Insulin-like Growth Factor) -I, IGF-II or IGFBP-3 (IGF-binding Protein-3): A nested case-control study in a large scale cohort study in Japan
    Kiyoko Yagyu
    Department of Public Health, Aichi Medical University School of Medicine, Japan
    Asian Pac J Cancer Prev 10:63-7. 2009
    ..Associations between IGF-I or IGF-II and gallbladder or bile duct cancer thus were lacking or very weak. The observed U- and inverse U-shaped association of IGFBP-3 with the cancers is not suggestive of any meaningful relationships...
  11. ncbi request reprint Serum soluble fas levels and superoxide dismutase activity and the risk of death from pancreatic cancer: A nested case-control study within the Japanese Collaborative Cohort Study
    Yingsong Lin
    Department of Public Health, Aichi Medical University School of Medicine, Japan
    Asian Pac J Cancer Prev 10:81-5. 2009
    ..Furthermore, no significant risk trends were noted. Our results do not support the hypothesis that serum sFas levels and SOD activity are associated with pancreatic cancer risk...
  12. ncbi request reprint Selection of cases and controls for the nested case-control study within the Japan Collaborative Cohort Study: the First-wave
    Akiko Tamakoshi
    Department of Public Health, Aichi Medical University School of Medicine, Japan
    Asian Pac J Cancer Prev 10:1-5. 2009
    ....
  13. ncbi request reprint Insulin-like growth factor (IGF)-I, IGF-II, IGF binding protein-3, and risk of colorectal cancer: a nested case-control study in the Japan Collaborative Cohort study
    Sadao Suzuki
    Department of Public Health, Nagoya City University Graduate School of Medical Sciences, Japan
    Asian Pac J Cancer Prev 10:45-9. 2009
    ..Although these markers might be etiologically significant in relation to colorectal cancer, we did not obtain evidence supporting this hypothesis...
  14. ncbi request reprint Association of serum retinol and carotenoids with insulin-like growth factors and insulin-like growth factor binding protein-3 among control subjects of a nested case-control study in the Japan Collaborative Cohort Study
    Koji Suzuki
    Department of Public Health, Fujita Health University, Japan
    Asian Pac J Cancer Prev 10:29-35. 2009
    ....
  15. ncbi request reprint Serum oxidized low-density lipoprotein levels and risk of colorectal cancer: a case-control study nested in the Japan Collaborative Cohort Study
    Koji Suzuki
    Department of Public Health, Fujita Health University School of Health Sciences, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192, Japan
    Cancer Epidemiol Biomarkers Prev 13:1781-7. 2004
    ..045). Analyses restricted to colon cancer cases and corresponding controls yielded similar relationships between serum oxLDL and oLAB levels and risk. In conclusion, higher levels of serum oxLDL may increase risk of colorectal cancer...
  16. ncbi request reprint Risk factors for kidney cancer in a Japanese population: findings from the JACC Study
    Masakazu Washio
    Department of Public Health, Sapporo Medical University School of Medicine, Hokkaido, Japan
    J Epidemiol 15:S203-11. 2005
    ..Although the incidence of kidney cancer in Japan is lower than the rates in the other industrialized countries, there is no doubt that it is increasing...
  17. ncbi request reprint Relationship of soluble fas with body mass index in healthy Japanese adults
    Akiko Tamakoshi
    Department of Public Health, Aichi Medical University School of Medicine, Japan
    Asian Pac J Cancer Prev 10:41-4. 2009
    ..Our result suggests that serum sFas rises to down-regulate increased apoptosis in atherogenesis processes caused by obesity...
  18. ncbi request reprint Relationship of serum superoxide dismutase activity and lifestyle in healthy Japanese adults
    Masanori Nojima
    Department of Public Health, Sapporo Medical University School of Medicine, Japan
    Asian Pac J Cancer Prev 10:37-40. 2009
    ..In conclusion, our findings do suggest associations between serum SOD activity and lifestyle factors. However, for further study, establishment of a standard measurement method for SOD activity should be a high priority...
  19. ncbi request reprint Serum heat shock protein 70 levels and lung cancer risk: a case-control study nested in a large cohort study
    Koji Suzuki
    Department of Public Health, Fujita Health University School of Helath Sciences, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192, Japan
    Cancer Epidemiol Biomarkers Prev 15:1733-7. 2006
    ..029). High levels of serum Hsp70 might thus be associated with increased risk of lung cancer among Japanese males, although further studies are needed to clarify associations between chronic inflammation and lung cancer...
  20. doi request reprint Cigarette smoking and serum soluble Fas levels: Findings from the JACC study
    Akiko Tamakoshi
    Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan
    Mutat Res 679:79-83. 2009
    ..21 (95% CI: 2.14-2.27) ng/ml, 2.29 (2.22-2.36) ng/ml, and 2.36 (2.30-2.43) ng/ml, respectively. However, no dose-response relationship was observed between the number of cigarettes smoked per day and sFas levels among smokers...
  21. ncbi request reprint Association of abdominal obesity with decreased serum levels of carotenoids in a healthy Japanese population
    Koji Suzuki
    Department of Public Health, School of Health Sciences, Fujita Health University, 1 98 Dengakugakubo Kutsukake cho, Toyoake, Aichi 470 1192, Japan
    Clin Nutr 25:780-9. 2006
    ..Few epidemiological studies have investigated the relationship between abdominal adiposity and serum levels of carotenoids. This study investigated the relationship between total and abdominal obesity and serum levels of carotenoids...
  22. doi request reprint Soluble Fas level and cancer mortality: findings from a nested case-control study within a large-scale prospective study
    Akiko Tamakoshi
    Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan
    Int J Cancer 123:1913-6. 2008
    ..Our results suggest that serum sFas has a possibility to detect people at high risk for cancer prior to diagnosis, since it increased before cancer diagnosis in those apparently healthy people...
  23. ncbi request reprint Active smoking, passive smoking, and breast cancer risk: findings from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk
    Yingsong Lin
    Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan
    J Epidemiol 18:77-83. 2008
    ..We examined the association between breast cancer incidence and active and passive smoking in the Japan Collaborative Cohort Study for Evaluation of Cancer Risk...
  24. doi request reprint Effect of physical activity on breast cancer risk: findings of the Japan collaborative cohort study
    Sadao Suzuki
    Department of Public Health, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
    Cancer Epidemiol Biomarkers Prev 17:3396-401. 2008
    ..This study aimed to examine prospectively the association between physical activity and breast cancer risk in a non-Western population...
  25. ncbi request reprint Relationship between obesity and serum markers of oxidative stress and inflammation in Japanese
    Koji Suzuki
    Department of Public Health, Fujita Health University School of Health Sciences, Toyoake, Aichi 470 1192, Japan
    Asian Pac J Cancer Prev 4:259-66. 2003
    ....
  26. ncbi request reprint Effectiveness of cervical cancer screening over cervical cancer mortality among Japanese women
    Khandoker Aklimunnessa
    Department of Public Health, Sapporo Medical University School of Medicine, Sapporo 060 8556, Japan
    Jpn J Clin Oncol 36:511-8. 2006
    ..Therefore, the present study evaluated the association of CC mortality with self-reported CC screening and some other factors by a nationwide cohort study...
  27. ncbi request reprint Diabetes mellitus and kidney cancer risk: the results of Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study)
    Masakazu Washio
    Department of Public Health, Sapporo Medical University School of Medicine, Sapporo, Japan
    Int J Urol 14:393-7. 2007
    ..Diabetes mellitus (DM) is reported as being a risk factor associated with kidney cancer in Western countries. The incidence of both kidney cancer and DM is lower in Japan than the other developed countries, albeit on the rise...
  28. ncbi request reprint Association between Interleukin-1B C-31T polymorphism and obesity in Japanese
    Koji Suzuki
    Department of Public Health, School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan
    J Epidemiol 19:131-5. 2009
    ..However, the association between interleukin-1beta (IL-1beta) and obesity remains controversial. We therefore investigated the association between IL-1B C-31T polymorphism and obesity in Japanese...
  29. ncbi request reprint Dietary habits and risk of urothelial cancer death in a large-scale cohort study (JACC Study) in Japan
    Fumio Sakauchi
    Department of Public Health, Sapporo Medical University School of Medicine, Japan
    Nutr Cancer 50:33-9. 2004
    ..It was suggested that urothelial cancer death could be potentially preventable by smoking cessation and regular intake of milk and fruit...
  30. ncbi request reprint Stability of frozen serum levels of insulin-like growth factor-I, insulin-like growth factor-II, insulin-like growth factor binding protein-3, transforming growth factor beta, soluble Fas, and superoxide dismutase activity for the JACC study
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Japan
    J Epidemiol 15:S67-73. 2005
    ..We conducted to investigate whether levels of serum components measured after 9 years of frozen storage are stable or not...
  31. doi request reprint Association of serum carotenoids with high molecular weight adiponectin and inflammation markers among Japanese subjects
    Koji Suzuki
    Department of Public Health, Fujita Health University School of Health Sciences, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192, Japan
    Clin Chim Acta 411:1330-4. 2010
    ..However, no studies have investigated the association between serum concentrations of adiponectin and carotenoids in the general population...
  32. ncbi request reprint Mortality rates from cancer or all causes and SOD activity level and Zn/Cu ratio in peripheral blood: population-based follow-up study
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan
    J Epidemiol 12:14-21. 2002
    ..In contrast, serum TBARS levels do not appear to be a biomarker for the risk of death from cancer...
  33. doi request reprint Possible protective effect of serum beta-carotene levels on the association between interleukin-1B C-31T polymorphism and hypertension in a Japanese population
    Atsumi Yanagisawa
    Clinical Laboratory Medicine, Fujita Health University Graduate School of Health Research, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192, Japan
    Clin Nutr 28:198-202. 2009
    ..We investigated the effect of serum beta-carotene levels on the association between the interleukin-1beta (IL-1B) C-31T polymorphism and hypertension...
  34. doi request reprint Inverse association of serum carotenoids with prevalence of metabolic syndrome among Japanese
    Koji Suzuki
    Department of Public Health, Fujita Health University School of Health Sciences, Dengakugakubo, Kutsukake cho, Toyoake, Aichi, Japan
    Clin Nutr 30:369-75. 2011
    ..The purpose of this study was to examine the association of serum carotenoid levels, which have potent antioxidant effects, with metabolic syndrome and metabolic syndrome components in Japanese subjects...
  35. ncbi request reprint The relationship between smoking habits and serum levels of 8-OHdG, oxidized LDL antibodies, Mn-SOD and carotenoids in rural Japanese residents
    Koji Suzuki
    Department of Public Health, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan
    J Epidemiol 13:29-37. 2003
    ..Serum levels of 8-OHdG, oLAB, and carotenoids may be useful biomarkers of oxidative conditions affected by smoking...
  36. ncbi request reprint Relationship between serum carotenoids and hyperglycemia: a population-based cross-sectional study
    Koji Suzuki
    Department of Public Health, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan
    J Epidemiol 12:357-66. 2002
    ..22-0.65), 0.35 (0.21-0.59), 0.57 (0.35-0.93), 0.35 (0.20-0.59), and 0.88 (0.54-1.46) for high HbA1c, respectively. In conclusion, intake of vegetables and fruits rich in carotenoids might be a protective factor against hyperglycemia...
  37. doi request reprint Green tea consumption and the risk of pancreatic cancer in Japanese adults
    Yingsong Lin
    Department of Public Health, Aichi Medical University School of Medicine, Nagakute cho, Aichi, Japan
    Pancreas 37:25-30. 2008
    ..Green tea polyphenols have been shown to inhibit tumor growth in animal and in vitro studies. We examined the relationship between green tea consumption and the risk of death from pancreatic cancer in a large Japanese cohort...
  38. ncbi request reprint Association of serum carotenoid levels with N-terminal pro-brain-type natriuretic peptide: a cross-sectional study in Japan
    Koji Suzuki
    Department of Public Health, Fujita Health University School of Health Sciences, Toyoake, Aichi 470 1192, Japan
    J Epidemiol 23:163-8. 2013
    ..However, no studies have reported an association between serum carotenoids and N-terminal pro-brain-type natriuretic peptide (NT-proBNP) in the general population...
  39. pmc Blood pressure, levels of serum lipids, liver enzymes and blood glucose by aldehyde dehydrogenase 2 and drinking habit in Japanese men
    Sayuri Nakamura
    Department of Adult Nursing, Fujita Health University School of Health Sciences, 1 98 Dengakugakubo, Kutsukake cho, 470 1192, Toyoake, Aichi, Japan
    Environ Health Prev Med 11:82-8. 2006
    ..The association of blood pressure and levels of serum lipids, liver enzymes, blood glucose and aldehyde dehydrogenase 2 (ALDH2) with drinking habit was examined in Japanese men...
  40. ncbi request reprint A population-based follow-up study on mortality from cancer or cardiovascular disease and serum carotenoids, retinol and tocopherols in Japanese inhabitants
    Yoshinori Ito
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, 466 8550 Japan
    Asian Pac J Cancer Prev 7:533-46. 2006
    ..To investigate whether high serum levels of carotenoids can reduce mortality rates, a population-based follow-up study was conducted among Japanese inhabitants...
  41. ncbi request reprint A prospective study on the possible association between having children and colon cancer risk: findings from the JACC Study
    Koji Tamakoshi
    Department of Public Health Health Information Dynamics, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Cancer Sci 95:243-7. 2004
    ..From these prospective data, having children may reduce risk of colon cancer among women, but not among men, suggesting that modifications of hormone profiles secondary to pregnancies may influence female colon cancer risk...
  42. ncbi request reprint Dietary fiber and risk of colorectal cancer in the Japan collaborative cohort study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Cancer Epidemiol Biomarkers Prev 16:668-75. 2007
    ..The role of dietary fiber in the prevention of colorectal cancer seems to remain inconsistent, and further investigations in various populations are warranted. (..
  43. ncbi request reprint Concurrent chemoradiotherapy for limited-disease small cell lung cancer in elderly patients aged 75 years or older
    Toshio Shimizu
    Division of Internal Medicine and Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan
    Jpn J Clin Oncol 37:181-5. 2007
    ..The optimal treatment for limited-disease small cell lung cancer (LD-SCLC) in patients aged 75 years or older remains unknown...
  44. ncbi request reprint Cigarette smoking, alcohol drinking, and oral and pharyngeal cancer mortality in Japan
    R Ide
    Department of Clinical Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyusyu, Japan
    Oral Dis 14:314-9. 2008
    ..To prospectively examine the association of cigarette smoking and alcohol drinking with oral and pharyngeal carcinogenesis, we analyzed data from a nation-wide large-scale cohort study in Japan...
  45. ncbi request reprint Serum phytoestrogens and prostate cancer risk in a nested case-control study among Japanese men
    Kotaro Ozasa
    Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kamigyo ku, Kyoto 602 8566, Japan
    Cancer Sci 95:65-71. 2004
    ..39, 95% CI; 0.13, 0.89, trend P = 0.02 for the first dataset). Their effects seemed to be independent of serum sex hormones. In conclusion, serum genistein, daidzein, and equol seemed to dose-dependently reduce prostate cancer risk...
  46. pmc Significant association between Helicobacter pylori infection and serum C-reactive protein
    Yoshiko Ishida
    Department of Preventive Medicine, Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Med Sci 5:224-9. 2008
    ..Helicobacter pylori (H. pylori) infection in gastric mucosa may cause systemic inflammatory reaction. This study aimed to examine the association between the infection and serum high sensitivity C-reactive protein (hsCRP)...
  47. ncbi request reprint Attributable and absolute risk of lung cancer death by smoking status: findings from the Japan Collaborative Cohort Study
    Masahiko Ando
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Cancer 105:249-54. 2003
    ..For all current smokers, immediate cessation is encouraged because it offers the only realistic way to avoid a substantial increase in lung cancer mortality brought about by further continuation of smoking...
  48. ncbi request reprint Lung cancer mortality and body mass index in a Japanese cohort: findings from the Japan Collaborative Cohort Study (JACC Study)
    Takaaki Kondo
    Department of Medical Technology, Nagoya University School of Health Sciences, 1 20 Daikominami 1 chome, Nagoya, Japan
    Cancer Causes Control 18:229-34. 2007
    ..To determine the relationship of body mass index (BMI) and BMI changes during adulthood to lung cancer mortality in a large-sized Japanese cohort...
  49. ncbi request reprint Smoking and colorectal cancer in a non-Western population: a prospective cohort study in Japan
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464 8681, Japan
    J Epidemiol 13:323-32. 2003
    ..The risk of colorectal cancer in relation to smoking habits has been examined mostly in Caucasians, and evidence for other ethnic groups is still scarce...
  50. ncbi request reprint Cardiovascular disease mortality and serum carotenoid levels: a Japanese population-based follow-up study
    Yoshinori Ito
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    J Epidemiol 16:154-60. 2006
    ..Some observational epidemiologic studies suggest that dietary and serum carotenoids are associated with reduced cardiovascular disease mortality...
  51. ncbi request reprint Perceived psychologic stress and colorectal cancer mortality: findings from the Japan Collaborative Cohort Study
    Masayo Kojima
    Department of Health Promotion and Preventive Medicine, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
    Psychosom Med 67:72-7. 2005
    ..The purpose of this research was to examine the relationship between perceived psychologic stress and colorectal cancer mortality in a prospective large-scale study...
  52. ncbi request reprint Glucose intolerance and colorectal cancer risk in a nested case-control study among Japanese People
    Kotaro Ozasa
    Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Japan
    J Epidemiol 15:S180-4. 2005
    ..Glucose intolerance may increase the risk of developing colorectal cancer...
  53. ncbi request reprint Alcohol consumption and colorectal cancer risk: findings from the JACC Study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    J Epidemiol 15:S173-9. 2005
    ..Because alcohol drinking is a potential risk factor for colorectal cancer, the trend in alcohol consumption in Japan may partly explain the increase in incidence and mortality rates of this malignancy until 1990-1995...
  54. ncbi request reprint Medical history of circulatory diseases and colorectal cancer death in the JACC Study
    Yoshiyuki Watanabe
    Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Japan
    J Epidemiol 15:S168-72. 2005
    ..Host factors expressed by individual past medical history of hypertension, stroke, and myocardial infarction may have a relationship with colorectal cancer...
  55. ncbi request reprint Diet and colorectal cancer mortality: results from the Japan Collaborative Cohort Study
    Masayo Kojima
    Department of Health Promotion and Preventive Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho, Nagoya, Japan
    Nutr Cancer 50:23-32. 2004
    ..Further investigation is therefore necessary to confirm the association between diet and colorectal cancer, especially by subsites and gender...
  56. ncbi request reprint Updated information on risk factors for lung cancer: findings from the JACC Study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Japan
    J Epidemiol 15:S134-9. 2005
    ..Updated information on risk factors for lung cancer, therefore, is of great importance. The Japan Collaborative Cohort Study, a large prospective study started in 1988, has provided such information...
  57. ncbi request reprint Leptin is associated with an increased female colorectal cancer risk: a nested case-control study in Japan
    Koji Tamakoshi
    Department of Public Health Health Information Dynamics, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Oncology 68:454-61. 2005
    ..To elucidate whether leptin is involved in the etiology of female colorectal cancer...
  58. ncbi request reprint Serum insulin-like growth factors, insulin-like growth factor-binding protein-3, and risk of lung cancer death: a case-control study nested in the Japan Collaborative Cohort (JACC) Study
    Kenji Wakai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya 466 8550, Japan
    Jpn J Cancer Res 93:1279-86. 2002
    ..A higher level of circulating IGFBP-3 and / or IGF-II may decrease lung cancer risk. Elevated serum IGF-I may increase the risk, but this could partly be attributable to latent tumors...
  59. ncbi request reprint Profile of the JACC study
    Akiko Tamakoshi
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    J Epidemiol 15:S4-8. 2005
    ..A large-scale population-based cohort study would offer the best evidence of a relation between lifestyle and cancer...
  60. ncbi request reprint Serum carotenoids and other antioxidative substances associated with urothelial cancer risk in a nested case-control study in Japanese men
    Kotaro Ozasa
    Department of Epidemiology for Community Health and Medicin, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan
    J Urol 173:1502-6. 2005
    ..We assayed whether high serum carotenoids and antioxidative substances decrease the risk of urothelial cancer in a case-control study nested in a community based cohort in Japan, that is the Japan Collaborative Cohort Study...
  61. ncbi request reprint Serum carotenoids, retinol, and tocopherols, and colorectal cancer risk in a Japanese cohort: effect modification by sex for carotenoids
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Institute, Nagoya 464 8681, Japan
    Nutr Cancer 51:13-24. 2005
    ..010) and 0.29 (0.07-1.17; trend P = 0.098), respectively. The effects of some carotenoids on colorectal cancer risk may be modified by sex or by factors associated with sex, including smoking and drinking habits...
  62. ncbi request reprint Serum levels of polyunsaturated fatty acids and risk of colorectal cancer: a prospective study
    Masayo Kojima
    Department of Health Promotion and Preventive Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    Am J Epidemiol 161:462-71. 2005
    ..No adverse effects of high serum levels of omega-6 polyunsaturated fatty acids on colorectal cancer risk were detected...
  63. ncbi request reprint Dietary habits and risk of urothelial cancer incidence in the JACC Study
    Fumio Sakauchi
    Department of Public Health, Sapporo Medical University School of Medicine
    J Epidemiol 15:S190-5. 2005
    ..In the present study, the associations of dietary habits with the risk of urothelial cancer incidence were evaluated taking into consideration sex, age, and smoking habits...
  64. ncbi request reprint Association of serum carotenoid concentration and dietary habits among the JACC Study subjects
    Kotaro Ozasa
    Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Japan
    J Epidemiol 15:S220-7. 2005
    ....
  65. ncbi request reprint Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study
    Kotaro Ozasa
    Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Japan
    J Epidemiol 15:S196-202. 2005
    ....
  66. ncbi request reprint A prospective study of reproductive and menstrual factors and colon cancer risk in Japanese women: findings from the JACC study
    Koji Tamakoshi
    Department of Public Health Health Information Dynamics, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya 466 8550, Japan
    Cancer Sci 95:602-7. 2004
    ....
  67. ncbi request reprint Prospective cohort study of the risk of prostate cancer among rotating-shift workers: findings from the Japan collaborative cohort study
    Tatsuhiko Kubo
    Department of Clinical Epidemiology, University of Occupational and Environmental Health, Kitakyushu, Japan
    Am J Epidemiol 164:549-55. 2006
    ..2, 7.7), whereas fixed-night work was associated with a small and nonsignificant increase in risk. This report is the first known to reveal a significant relation between rotating-shift work and prostate cancer...
  68. ncbi request reprint Alcohol consumption and lung cancer mortality in Japanese men: results from Japan collaborative cohort (JACC) study
    Yoshikazu Nishino
    Division of Epidemiology, Miyagi Cancer Center Research Institute, Japan
    J Epidemiol 16:49-56. 2006
    ..The relationship between alcohol consumption and increased risk of lung cancer is controversial. This study was set up to investigate the association between alcohol consumption and death from lung cancer in a large Japanese cohort...
  69. ncbi request reprint High prevalence of HER-2/neu and p53 overexpression in inflammatory breast cancer
    Masataka Sawaki
    Department of Medical Oncology, Cancer Institute Hospital and Cancer Chemotherapy Center, Japanese Foundation for Cancer Research
    Breast Cancer 13:172-8. 2006
    ..We have summarized a single-center experience involving IBC patients. Our objectives are to clarify molecular alterations of HER-2/neu and p53 in IBC and to investigate the prognostic factors...
  70. ncbi request reprint Intake frequency of fish and serum levels of long-chain n-3 fatty acids: a cross-sectional study within the Japan Collaborative Cohort Study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya, Japan
    J Epidemiol 15:211-8. 2005
    ..Whether reported fish consumption reflects the fatty acid intake, however, has to be elucidated...
  71. ncbi request reprint Genotype announcement to Japanese smokers who attended a health checkup examination
    Nobuyuki Hamajima
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    J Epidemiol 16:45-7. 2006
    ..Genotype announcement may be one of the effective methods to induce smoking cessation, but the studies are limited throughout the world...
  72. doi request reprint Epstein-Barr virus nuclear antigen 1-specific CD4+ T cells directly kill Epstein-Barr virus-carrying natural killer and T cells
    Ayako Demachi-Okamura
    Division of Immunology, Aichi Cancer Center Research Institute, Nagoya, Japan
    Cancer Sci 99:1633-42. 2008
    ....
  73. ncbi request reprint Possible interactions of the endothelial constitutive nitric oxide synthase genotype with alcohol drinking and walking time for high serum uric acid levels among Japanese
    Kazuko Nishio
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Metabolism 54:1302-8. 2005
    ..These findings would be informative for men with high SUA levels...
  74. ncbi request reprint Short-course palliative radiotherapy for airway stenosis in non-small cell lung cancer
    Keiji Nihei
    Division of Radiation Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa 277 8577, Japan
    Int J Clin Oncol 7:284-8. 2002
    ..We investigated, retrospectively, the outcome of short-course palliative radiotherapy for airway stenosis in non-small cell lung cancer...
  75. ncbi request reprint Pro-gastrin-releasing peptide as a factor predicting the incidence of brain metastasis in patients with small cell lung carcinoma with limited disease receiving prophylactic cranial irradiation
    Kan Yonemori
    Division of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan
    Cancer 104:811-6. 2005
    ..The authors retrospectively analyzed the characteristics of the first failure event due to brain metastasis (FBM) in patients treated with PCI...
  76. ncbi request reprint Altered myocardial flow reserve and endothelial function late after Kawasaki disease
    Hideto Furuyama
    Department of Pediatrics, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Pediatr 142:149-54. 2003
    ..Our purpose was to assess myocardial flow reserve (MFR) and endothelial function in various myocardial regions after KD by using positron emission tomography...
  77. ncbi request reprint Absence of associations between influenza-associated encephalopathy and human herpesvirus 6 or human herpesvirus 7
    Jun ichi Kawada
    Department of Pediatrics, Nagoya University School of Medicine, Japan
    Pediatr Infect Dis J 22:115-9. 2003
    ..AIM To confirm or refute the association between influenza-associated encephalopathy and HHV-6 or HHV-7...
  78. ncbi request reprint Associations between serum C-reactive protein (CRP) levels and polymorphisms of CRP, interleukin 1B, and tumor necrosis factor genes among Japanese health checkup examinees
    Masato Kikuchi
    Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 8:87-92. 2007
    ..Since the biological mechanism is not clear, further investigations are required to confirm the association...
  79. ncbi request reprint Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell growth in vitro and in vivo
    Hiroaki Uchida
    Department of Molecular Medicine, Sapporo Medical University, Sapporo 060 8556, Japan
    Mol Ther 10:162-71. 2004
    ..Moreover, intratumoral injection of Adv-siSurv significantly suppressed tumor growth in a xenograft model using U251 glioma cells. This novel modality may be a promising tool for cancer therapy...
  80. ncbi request reprint Interferon-gamma differentially regulates susceptibility of lung cancer cells to telomerase-specific cytotoxic T lymphocytes
    Kouhei Tajima
    Division of Immunology, Aichi Cancer Center Research Institute, Nagoya, Japan
    Int J Cancer 110:403-12. 2004
    ....
  81. doi request reprint Alcohol consumption and mortality from stroke and coronary heart disease among Japanese men and women: the Japan collaborative cohort study
    Satoyo Ikehara
    Public Health, Department of Social and Environmental Medicine, Osaka University, Graduate School of Medicine, Osaka, Japan
    Stroke 39:2936-42. 2008
    ..However, the sex-specific association between alcohol consumption and mortality from stroke and coronary heart disease remains unclear...
  82. ncbi request reprint Improvement in the prognosis of Japanese breast cancer patients from 1946 to 2001--an institutional review
    Masataka Yoshimoto
    Department of Breast Surgery, Cancer Institute Hospital, Kami Ikebukuro 1 37 1, Toshima ku, Tokyo 170 8455, Japan
    Jpn J Clin Oncol 34:457-62. 2004
    ..Breast cancer has emerged as one of the most frequent malignancies among Japanese women; however, the long-term survival of Japanese breast cancer patients is uncertain...