N Fujise

Summary

Country: Japan

Publications

  1. ncbi request reprint Characterization of structural domains of human osteoclastogenesis inhibitory factor
    K Yamaguchi
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, 519 Ishibashi machi, Shimotsuga gun, Tochigi 329 0512, Japan
    J Biol Chem 273:5117-23. 1998
  2. ncbi request reprint Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro
    H Yasuda
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, Tochigi, Japan
    Endocrinology 139:1329-37. 1998
  3. ncbi request reprint Possible involvement of p21/waf1 in the growth inhibition of HepG2 cells induced by hepatocyte growth factor
    N Shima
    Research Institute of Life Science, Snow Brand Milk Products, CO, Ltd, Tochigi, Japan
    J Cell Physiol 177:130-6. 1998
  4. ncbi request reprint Characterization of monomeric and homodimeric forms of osteoclastogenesis inhibitory factor
    A Tomoyasu
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, Tochigi, Japan
    Biochem Biophys Res Commun 245:382-7. 1998
  5. ncbi request reprint Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin
    A Mizuno
    Research Institute of Life Science, Snow Brand Milk Products, CO, Ltd, Tochigi, Japan
    Biochem Biophys Res Commun 247:610-5. 1998
  6. ncbi request reprint Effective administration route for the deleted form of hepatocyte growth factor To exert its pharmacological effects
    Y Uematsu
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, 519 Shimoishibashi, Ishibashi Machi, Shimotsuga gun, Tochigi 329 0512
    J Pharm Sci 88:131-5. 1999

Collaborators

  • Y Sato
  • K Yano
  • H Ozawa
  • E Gohda
  • K Irie
  • Norio Amizuka
  • K Higashio
  • H Yasuda
  • T Morinaga
  • E Tsuda
  • N Shima
  • K Yamaguchi
  • M Goto
  • Y Uematsu
  • A Tomoyasu
  • A Murakami
  • S Mochizuki
  • N Nakagawa
  • T Kanno
  • A Mizuno
  • K Kohsaka
  • H Masunaga
  • N Washida
  • M Kuriyama
  • F Kobayashi
  • G K Michalopoulos
  • D B Stolz
  • M Miyazaki
  • S i Mochizuki
  • T Gomibuchi
  • M Kinosaki

Detail Information

Publications6

  1. ncbi request reprint Characterization of structural domains of human osteoclastogenesis inhibitory factor
    K Yamaguchi
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, 519 Ishibashi machi, Shimotsuga gun, Tochigi 329 0512, Japan
    J Biol Chem 273:5117-23. 1998
    ....
  2. ncbi request reprint Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro
    H Yasuda
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, Tochigi, Japan
    Endocrinology 139:1329-37. 1998
    ..These results suggest that the sites are involved in cell-to-cell signaling between stromal cells and osteoclast progenitors and that OPG/OCIF inhibits osteoclastogenesis by interrupting the signaling through the sites...
  3. ncbi request reprint Possible involvement of p21/waf1 in the growth inhibition of HepG2 cells induced by hepatocyte growth factor
    N Shima
    Research Institute of Life Science, Snow Brand Milk Products, CO, Ltd, Tochigi, Japan
    J Cell Physiol 177:130-6. 1998
    ..Immunoprecipitation analysis revealed accumulation of cdk2-associated p21/waf1 in the HGF-treated HepG2. Together, the results suggest that sustained induction of p21/waf1 mediates growth inhibition in HepG2 in the presence of HGF...
  4. ncbi request reprint Characterization of monomeric and homodimeric forms of osteoclastogenesis inhibitory factor
    A Tomoyasu
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, Tochigi, Japan
    Biochem Biophys Res Commun 245:382-7. 1998
    ....
  5. ncbi request reprint Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin
    A Mizuno
    Research Institute of Life Science, Snow Brand Milk Products, CO, Ltd, Tochigi, Japan
    Biochem Biophys Res Commun 247:610-5. 1998
    ..These results demonstrate that OCIF/OPG is a key factor acting as a negative regulator against osteoclastogenesis. The OCIF/OPG knockout mice provide the first animal model for osteoporosis without other obvious abnormalities...
  6. ncbi request reprint Effective administration route for the deleted form of hepatocyte growth factor To exert its pharmacological effects
    Y Uematsu
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, 519 Shimoishibashi, Ishibashi Machi, Shimotsuga gun, Tochigi 329 0512
    J Pharm Sci 88:131-5. 1999
    ..The steady-state level of dHGF was 7- to 9-fold higher in liver than in plasma, and the higher level in liver was sustained beyond the steady-state...