Y Mizui

Summary

Affiliation: Eisai Co
Country: Japan

Publications

  1. ncbi request reprint Assignment of a disintegrin and metalloproteinase domain 10 (Adam10) gene to mouse chromosome 9
    K Yamazaki
    Tsukuba Research Laboratories, Eisai Co, Ltd, Ibaraki, Japan
    Genomics 46:528-9. 1997
  2. ncbi request reprint Characterization of 5'-flanking region of human aggrecanase-1 (ADAMTS4) gene
    Y Mizui
    Tsukuba Research Laboratories, Eisai Co, Ltd, Ibaraki, Japan
    Mol Biol Rep 27:167-73. 2000
  3. ncbi request reprint Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities
    Yoshiharu Mizui
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3 Tokodai, Tsukuba, Ibaraki 300 2635, Japan
    J Antibiot (Tokyo) 57:188-96. 2004
  4. ncbi request reprint Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23
    K Sagane
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3, Tokodai, Tsukuba, Ibaraki 300 2635, Japan
    Gene 236:79-86. 1999
  5. ncbi request reprint Genetic mapping of mouse tumor necrosis factor-alpha converting enzyme (TACE) to chromosome 12
    K Yamazaki
    Tsukuba Research Laboratories, Eisai Co, Ltd, Ibaraki, Japan
    Genomics 49:336-7. 1998
  6. ncbi request reprint cDNA cloning of mouse tumor necrosis factor-alpha converting enzyme (TACE) and partial analysis of its promoter
    Y Mizui
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3, Tokodai, Tsukuba, Ibaraki 300 2635, Japan
    Gene 233:67-74. 1999
  7. ncbi request reprint Cloning and characterization of mouse glutamine:fructose-6-phosphate amidotransferase 2 gene promoter
    K Yamazaki
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3, Tokodai, Tsukuba, 300 2635, Ibaraki, Japan
    Gene 261:329-36. 2000
  8. ncbi request reprint Radiation hybrid mapping of human ADAM10 gene to chromosome 15
    K Yamazaki
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3, Tokodai, Tsukuba, Ibaraki 300 26, Japan
    Genomics 45:457-9. 1997
  9. ncbi request reprint Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cells
    Y Shinozuka
    Department of Biology, Faculty of Science, Ochanomizu University, Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan
    Biochem Biophys Res Commun 287:229-35. 2001

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Assignment of a disintegrin and metalloproteinase domain 10 (Adam10) gene to mouse chromosome 9
    K Yamazaki
    Tsukuba Research Laboratories, Eisai Co, Ltd, Ibaraki, Japan
    Genomics 46:528-9. 1997
  2. ncbi request reprint Characterization of 5'-flanking region of human aggrecanase-1 (ADAMTS4) gene
    Y Mizui
    Tsukuba Research Laboratories, Eisai Co, Ltd, Ibaraki, Japan
    Mol Biol Rep 27:167-73. 2000
    ..Thus, the NFI site is involved in negative regulation of the human ADAMTS4 promoter activity in chondrocytes...
  3. ncbi request reprint Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities
    Yoshiharu Mizui
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3 Tokodai, Tsukuba, Ibaraki 300 2635, Japan
    J Antibiot (Tokyo) 57:188-96. 2004
    ..For the reason of their novel mechanism of action and excellent in vivo efficacy, pladienolides appear to have major potential for use in cancer treatment...
  4. ncbi request reprint Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23
    K Sagane
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3, Tokodai, Tsukuba, Ibaraki 300 2635, Japan
    Gene 236:79-86. 1999
    ..The structures of these ADAM proteins strongly suggest that they could function as integrin receptors. The implications of the cellular disintegrins in neural development are discussed...
  5. ncbi request reprint Genetic mapping of mouse tumor necrosis factor-alpha converting enzyme (TACE) to chromosome 12
    K Yamazaki
    Tsukuba Research Laboratories, Eisai Co, Ltd, Ibaraki, Japan
    Genomics 49:336-7. 1998
  6. ncbi request reprint cDNA cloning of mouse tumor necrosis factor-alpha converting enzyme (TACE) and partial analysis of its promoter
    Y Mizui
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3, Tokodai, Tsukuba, Ibaraki 300 2635, Japan
    Gene 233:67-74. 1999
    ..Finally, we found that the mouse TACE promoter at nt -2304 to -1 also worked in NIH3T3, 3T3L1 and C6 cell lines...
  7. ncbi request reprint Cloning and characterization of mouse glutamine:fructose-6-phosphate amidotransferase 2 gene promoter
    K Yamazaki
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3, Tokodai, Tsukuba, 300 2635, Ibaraki, Japan
    Gene 261:329-36. 2000
    ..Electrophoretic mobility shift assay showed DNA-protein binding at both Sp1 sites. We also compared the promoter activities of mouse GFAT1 and GFAT2 in several cell lines...
  8. ncbi request reprint Radiation hybrid mapping of human ADAM10 gene to chromosome 15
    K Yamazaki
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3, Tokodai, Tsukuba, Ibaraki 300 26, Japan
    Genomics 45:457-9. 1997
  9. ncbi request reprint Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cells
    Y Shinozuka
    Department of Biology, Faculty of Science, Ochanomizu University, Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan
    Biochem Biophys Res Commun 287:229-35. 2001
    ..These results suggest that glucocorticoids impair insulin synthesis in HIT-T15 cells by decreasing PDX-1 and BETA2/NeuroD and that enhancement of HES-1 expression is involved in this regulation...