Hitoshi Hasegawa

Summary

Affiliation: Ehime University
Country: Japan

Publications

  1. doi request reprint Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β production
    Hitoshi Hasegawa
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon, Ehime 791 0295, Japan
    Biochem Biophys Res Commun 415:526-31. 2011
  2. ncbi request reprint Molecular cloning and expression of mouse homologue of SFA-1/PETA-3 (CD151), a member of the transmembrane 4 superfamily
    H Hasegawa
    First Department of Internal Medicine, Ehime University, School of Medicine, Shigenobu, Japan
    Biochim Biophys Acta 1353:125-30. 1997
  3. ncbi request reprint A case of Weber-Christian disease associated with myelodysplastic syndrome
    Nobumasa Hojo
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Onsen gun, Ehime, 791 0295, Japan
    Mod Rheumatol 14:73-6. 2004
  4. ncbi request reprint Chemokine blockade for lupus model mice
    Hitoshi Hasegawa
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Shitsukawa 454, Toon City, Ehime 791 0295, Japan
    Front Biosci 13:2900-8. 2008
  5. ncbi request reprint Antagonist of interferon-inducible protein 10/CXCL10 ameliorates the progression of autoimmune sialadenitis in MRL/lpr mice
    Hitoshi Hasegawa
    First Department of Internal Medicine, Ehime University School of Medicine, Ehime, Japan
    Arthritis Rheum 54:1174-83. 2006
  6. ncbi request reprint Therapeutic effect of CXCR3-expressing regulatory T cells on liver, lung and intestinal damages in a murine acute GVHD model
    H Hasegawa
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Ehime, Japan
    Gene Ther 15:171-82. 2008
  7. pmc Therapy for pneumonitis and sialadenitis by accumulation of CCR2-expressing CD4+CD25+ regulatory T cells in MRL/lpr mice
    Hitoshi Hasegawa
    First Department of Internal Medicine, Division of Pathogenomics, Ehime University School of Medicine, Shitsukawa 454, Toon City, Ehime 791 0295, Japan
    Arthritis Res Ther 9:R15. 2007
  8. ncbi request reprint Antagonist of monocyte chemoattractant protein 1 ameliorates the initiation and progression of lupus nephritis and renal vasculitis in MRL/lpr mice
    Hitoshi Hasegawa
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Ehime, Japan
    Arthritis Rheum 48:2555-66. 2003
  9. ncbi request reprint SFA-1/PETA-3 (CD151), a member of the transmembrane 4 superfamily, associates preferentially with alpha 5 beta 1 integrin and regulates adhesion of human T cell leukemia virus type 1-infected T cells to fibronectin
    H Hasegawa
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Japan
    J Immunol 161:3087-95. 1998
  10. ncbi request reprint Increased chemokine receptor CCR7/EBI1 expression enhances the infiltration of lymphoid organs by adult T-cell leukemia cells
    H Hasegawa
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Ehime 791 0295, Japan
    Blood 95:30-8. 2000

Detail Information

Publications51

  1. doi request reprint Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β production
    Hitoshi Hasegawa
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon, Ehime 791 0295, Japan
    Biochem Biophys Res Commun 415:526-31. 2011
    ..LPC is a bioactive lysolipid highly abundant in the circulation. Therefore, LPC may contribute to the maintenance and function of human nTregs in vivo...
  2. ncbi request reprint Molecular cloning and expression of mouse homologue of SFA-1/PETA-3 (CD151), a member of the transmembrane 4 superfamily
    H Hasegawa
    First Department of Internal Medicine, Ehime University, School of Medicine, Shigenobu, Japan
    Biochim Biophys Acta 1353:125-30. 1997
    ..The expression patterns of mouse and human CD151 genes are similar...
  3. ncbi request reprint A case of Weber-Christian disease associated with myelodysplastic syndrome
    Nobumasa Hojo
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Onsen gun, Ehime, 791 0295, Japan
    Mod Rheumatol 14:73-6. 2004
    ..This finding appears to implicate a T-cell immune response in the pathogenesis of Weber-Christian disease...
  4. ncbi request reprint Chemokine blockade for lupus model mice
    Hitoshi Hasegawa
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Shitsukawa 454, Toon City, Ehime 791 0295, Japan
    Front Biosci 13:2900-8. 2008
    ..In this article, we review the role of chemokines and chemokine receptors involved in the pathogenesis of autoimmune diseases and the therapeutic approach of chemokine blockade in lupus model mice...
  5. ncbi request reprint Antagonist of interferon-inducible protein 10/CXCL10 ameliorates the progression of autoimmune sialadenitis in MRL/lpr mice
    Hitoshi Hasegawa
    First Department of Internal Medicine, Ehime University School of Medicine, Ehime, Japan
    Arthritis Rheum 54:1174-83. 2006
    ..We undertook the present study to investigate the expression of chemokines during the development of autoimmune sialadenitis in MRL/lpr mice and the therapeutic effect of chemokine antagonists on sialadenitis...
  6. ncbi request reprint Therapeutic effect of CXCR3-expressing regulatory T cells on liver, lung and intestinal damages in a murine acute GVHD model
    H Hasegawa
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Ehime, Japan
    Gene Ther 15:171-82. 2008
    ..This method may provide a new therapeutic approach for organ damage in acute GVHD...
  7. pmc Therapy for pneumonitis and sialadenitis by accumulation of CCR2-expressing CD4+CD25+ regulatory T cells in MRL/lpr mice
    Hitoshi Hasegawa
    First Department of Internal Medicine, Division of Pathogenomics, Ehime University School of Medicine, Shitsukawa 454, Toon City, Ehime 791 0295, Japan
    Arthritis Res Ther 9:R15. 2007
    ..This method may provide a new therapeutic approach for organ-specific autoimmune diseases in which the target antigens remain undefined...
  8. ncbi request reprint Antagonist of monocyte chemoattractant protein 1 ameliorates the initiation and progression of lupus nephritis and renal vasculitis in MRL/lpr mice
    Hitoshi Hasegawa
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Ehime, Japan
    Arthritis Rheum 48:2555-66. 2003
    ..To examine whether chemokine antagonists inhibit the initiation and progression of lupus nephritis in MRL/lpr mice...
  9. ncbi request reprint SFA-1/PETA-3 (CD151), a member of the transmembrane 4 superfamily, associates preferentially with alpha 5 beta 1 integrin and regulates adhesion of human T cell leukemia virus type 1-infected T cells to fibronectin
    H Hasegawa
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Japan
    J Immunol 161:3087-95. 1998
    ..This suggests that the increased expression of these integrins may contribute to lymphoma formation through the adhesion of ATL cells to the extracellular matrix and dendritic cells, rather than contributing to transmigration...
  10. ncbi request reprint Increased chemokine receptor CCR7/EBI1 expression enhances the infiltration of lymphoid organs by adult T-cell leukemia cells
    H Hasegawa
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Ehime 791 0295, Japan
    Blood 95:30-8. 2000
    ..These findings suggest that increased CCR7/EBI1 expression plays a role in lymphoid organ infiltration of ATL cells. (Blood. 2000; 30-38)..
  11. ncbi request reprint Increased chemokine receptor expression and the infiltration of lymphoid organs
    H Hasegawa
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Japan
    Leuk Lymphoma 42:1221-8. 2001
    ..Chemokines are known to mediate their effects through 7 transmembrane-domain G-protein-coupled receptors. Here, we review the role of chemokines and their receptors in lymphocyte's migration into lymphoid organs...
  12. ncbi request reprint IK cytokine ameliorates the progression of lupus nephritis in MRL/lpr mice
    Masatake Muraoka
    Ehime University School of Medicine, Ehime, Japan
    Arthritis Rheum 54:3591-600. 2006
    ..In this study, we investigated whether IK cytokine can ameliorate the progression of lupus nephritis in MRL/lpr mice...
  13. ncbi request reprint Antagonist of fractalkine (CX3CL1) delays the initiation and ameliorates the progression of lupus nephritis in MRL/lpr mice
    Atsushi Inoue
    Ehime University School of Medicine, Ehime, Japan
    Arthritis Rheum 52:1522-33. 2005
    ..Fractalkine (Fkn)/CX3CL1 and its receptor, CX3CR1, form one such chemokine system. We therefore undertook this study to investigate whether Fkn antagonist inhibits the initiation and progression of lupus nephritis in MRL/lpr mice...
  14. ncbi request reprint Antagonist of secondary lymphoid-tissue chemokine (CCR ligand 21) prevents the development of chronic graft-versus-host disease in mice
    Miho Sasaki
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Ehime, Japan
    J Immunol 170:588-96. 2003
    ..Therefore, our results suggest that SLC antagonist has beneficial effects for the prevention of chronic GVHD...
  15. pmc Human herpesvirus 6 infection impairs Toll-like receptor signaling
    Yuichi Murakami
    Departmemt of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, Japan
    Virol J 7:91. 2010
    ..These data show that HHV-6 impairs intracellular signaling through TLRs indicating the novel mechanism of HHV-6-mediated immunomodulation...
  16. ncbi request reprint Germ cell tumor concomitant with acquired immune deficiency syndrome
    Toshiki Ochi
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon
    Intern Med 48:2129-32. 2009
    ....
  17. doi request reprint Clinical significance of co-expression of CD21 and LFA-1 in B-cell lymphoma
    Kazushi Tanimoto
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon, Ehime 791 0295, Japan
    Int J Hematol 89:497-507. 2009
    ..These data suggest that CD21 is tightly related to LFA-1 expression in BCL and the absence of CD21/LFA-1 expression is associated with pleural/peritoneal fluid involvement by BCL, a potential indicator of disease progression of BCL...
  18. doi request reprint CD151 regulates HGF-stimulated morphogenesis of human breast cancer cells
    Sebastian K Klosek
    Department of Oral and Maxillofacial Surgery, Ehime University Graduate School of Medicine, 454 Shitsukawa, Toon, Ehime 791 0295, Japan
    Biochem Biophys Res Commun 379:1097-100. 2009
    ..Hence, the regulation of CD151 expression might contribute to changes in HGF/c-Met signaling and thereby modulate the phenotypic characteristics of cancer cells...
  19. ncbi request reprint CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase
    Masashi Kohno
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Ehime 791 0295, Japan
    Int J Cancer 97:336-43. 2002
    ..These findings indicate that the CD151 molecule enhances cell motility, invasion and metastasis of cancer cells and that FAK is needed for these events through CD151...
  20. ncbi request reprint [Rituximab for managing refractory thrombotic thrombocytopenic purpura: a report of three cases]
    Jun Yamanouchi
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Japan
    Rinsho Ketsueki 54:205-9. 2013
    ..These results suggest that rituximab should be given as early as possible in TTP, but large clinical studies are required to determine the optimal use of rituximab in TTP...
  21. doi request reprint Identification of an epitope derived from CML66, a novel tumor-associated antigen expressed broadly in human leukemia, recognized by human leukocyte antigen-A*2402-restricted cytotoxic T lymphocytes
    Koichiro Suemori
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon, Ehime 791 0295, Japan
    Cancer Sci 99:1414-9. 2008
    ..These data indicate that the CML66-derived epitope identified in the present study is a new target antigen for cellular immunotherapy of human leukemia...
  22. doi request reprint Syndrome of inappropriate secretion of antidiuretic hormone induced by tacrolimus in a patient with systemic lupus erythematosus
    Koichiro Suemori
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, 791 0295, Japan
    Mod Rheumatol 21:97-100. 2011
    ..This case strongly suggests that SIADH is a potentially important complication of tacrolimus administration, irrespective of dosage, and should be borne in mind whenever the drug is used...
  23. ncbi request reprint Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18
    Masashi Kohno
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon, Japan
    Biochem Biophys Res Commun 347:827-32. 2006
    ..NAGly also inhibited forskolin-induced cAMP production in a pertussis toxin-sensitive manner in the GPR18-transfected CHO cells. This is the first study to demonstrate that NAGly is a natural ligand for GPR18...
  24. ncbi request reprint Transcriptional downregulation of DC-SIGN in human herpesvirus 6-infected dendritic cells
    Hironari Niiya
    First Department of Internal Medicine and Department of Dermatology, Ehime University School of Medicine, Shigenobu, Ehime 791 0295, Japan
    J Gen Virol 85:2639-42. 2004
    ..The present study demonstrates for the first time that expression of DC-SIGN is altered at the transcriptional level by virus infection...
  25. doi request reprint Peroxisome proliferator-activated receptor α and γ agonists together with TGF-β convert human CD4+CD25- T cells into functional Foxp3+ regulatory T cells
    Jin Lei
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Ehime, Japan
    J Immunol 185:7186-98. 2010
    ..Moreover, trichostatin A and retinoic acid enhanced the generation of iTregs synergistically with PPARα and PPARγ agonists...
  26. ncbi request reprint Endothelial adhesion molecules in glomerular lesions: association with their severity and diversity in lupus models
    Kimihiko Nakatani
    Department of Pathology and Department of Internal Medicine, Ehime University School of Medicine, Onsen gun, Ehime, Japan
    Kidney Int 65:1290-300. 2004
    ..To clarify whether vascular endothelial adhesion molecules in glomeruli might contribute to the severity and diversity of glomerular lesions in lupus nephritis, their expression in lupus models was analyzed...
  27. ncbi request reprint Munchausen syndrome with foreign-body granuloma mimicking rheumatic diseases
    Masashi Kohno
    First Department of Internal Medicine, Ehime University School of Medicine, Shigenobu, Onsen gun, Ehime, 791 0295, Japan
    Mod Rheumatol 14:66-9. 2004
    ..Because the nursing staff later discovered that the patient had been carrying out self-injection, a diagnosis of Munchausen syndrome was made. Munchausen syndrome should be included in the differential diagnosis of rheumatic diseases...
  28. doi request reprint Protein kinase C inhibitor generates stable human tolerogenic dendritic cells
    Takuya Matsumoto
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon, Ehime 791 0295, Japan
    J Immunol 191:2247-57. 2013
    ..Conventional PKCI-treated DCs may be useful for tolerance-inducing therapy, as they satisfy the required functional characteristics for clinical-grade tolerogenic DCs. ..
  29. ncbi request reprint Absence of chlamydial infection in Japanese patients with ocular adnexal lymphoma of mucosa-associated lymphoid tissue
    Yoshihiro Yakushijin
    First Department of Internal Medicine, Ehime University School of Medicine, Ehime, Japan
    Int J Hematol 85:223-30. 2007
    ....
  30. ncbi request reprint CD151 forms a functional complex with c-Met in human salivary gland cancer cells
    Sebastian Krystian Klosek
    Department of Oral and Maxillofacial Surgery, Ehime University School of Medicine, Shitsukawa, Toon, Ehime 791 0295, Japan
    Biochem Biophys Res Commun 336:408-16. 2005
    ..These results suggest that CD151 forms a structural and functional complex with c-Met and integrin alpha3/alpha6, and exerts its oncogenic functions through excessive activation of the HGF/c-Met signalling pathway...
  31. ncbi request reprint Remitting seronegative symmetric synovitis with pitting edema: scintigraphic and magnetic resonance imaging findings
    Takashi Takeguchi
    Department of Radiology, Ehime University School of Medicine, Shigenbucho, Japan
    Clin Nucl Med 28:766-8. 2003
    ..The authors present scintigraphic and magnetic resonance images in a case of RS3PE...
  32. ncbi request reprint An Asian case of fibroblastic rheumatism: clinical, radiological, and histological features
    Shohei Watanabe
    Department of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan
    Mod Rheumatol 20:423-6. 2010
    ..This is the first FR published case of FR in an Asian individual, and 23 published cases were reviewed...
  33. ncbi request reprint Estimation of the initial dose setting of vancomycin therapy with use of cystatin C as a new marker of renal function
    Akihiro Tanaka
    Division of Pharmacy, Ehime University Hospital, Ehime, Japan
    Ther Drug Monit 29:261-4. 2007
    ..These results suggest that serum cystatin C is a good marker of renal function in comparison with serum creatinine for dose setting of vancomycin, especially in an elderly population...
  34. ncbi request reprint [A case of pyomyositis following influenza virus infection]
    Masashi Kohno
    First Department of Internal Medicine, Ehime University, School of Medicine
    Kansenshogaku Zasshi 77:505-9. 2003
    ..Pyomyositis following Influenza virus infection must be considered as a differential diagnosis of myalgia after Influenza virus infection...
  35. ncbi request reprint Preparation and characterization of recombinant murine p65/L-plastin expressed in Escherichia coli and high-titer antibodies against the protein
    Hiroto Shinomiya
    Department of Immunology and Host Defenses, Ehime University School of Medicine, Ehime 791 0295, Japan
    Biosci Biotechnol Biochem 67:1368-75. 2003
    ....
  36. ncbi request reprint Follicular dendritic cell tumor as an unknown primary tumor
    Yoshihiro Yakushijin
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Tohon shi, Ehime 791 0295, Japan
    Int J Clin Oncol 12:56-8. 2007
    ..In conclusion, we found this unknown primary tumor to be consistent with a follicular dendritic cell tumor with anaplastic features...
  37. ncbi request reprint Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry
    Yoichiro Takahashi
    Second Department of Internal Medicine, Akita University School of Medicine, Akita, Japan
    Biochem Biophys Res Commun 356:45-52. 2007
    ..These results reveal the essential role of Orai1 and its N-terminal sequence in SOCE...
  38. ncbi request reprint Chondroitin sulfate B exerts its inhibitory effect on secondary lymphoid tissue chemokine (SLC) by binding to the C-terminus of SLC
    Jun Hirose
    Molecular and Cellular Recognition, Osaka University Graduate School of Medicine C8, 2 2, Yamada oka, Suita, Osaka 565 0871, Japan
    Biochim Biophys Acta 1571:219-24. 2002
    ....
  39. ncbi request reprint Expression of CCR9 in HTLV-1+ T cells and ATL cells expressing Tax
    Daisuke Nagakubo
    Department of Microbiology and SORST, Kinki University School of Medicine, Osaka Sayama, Osaka, Japan
    Int J Cancer 120:1591-7. 2007
    ..Collectively, CCR9 is inducible in ATL cells expressing Tax and may play a role in the gastrointestinal involvement of ATL...
  40. ncbi request reprint Induction of an antitumor immunological response by an intratumoral injection of dendritic cells pulsed with genetically engineered Semliki Forest virus to produce interleukin-18 combined with the systemic administration of interleukin-12
    Ryuya Yamanaka
    Clinical Gene Therapy Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Neurosurg 99:746-53. 2003
    ..The aim of this study was to investigate further immunogene treatment of malignant brain tumor to improve its therapeutic efficacy...
  41. ncbi request reprint Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1-transformed T cells
    Osamu Yoshie
    Department of Microbiology, Kinki University School of Medicine, Osaka, Japan
    Blood 99:1505-11. 2002
    ..Thus, HTLV-1-infected CCR4(+) T cells may have growth advantages by deviating host immune responses to Th2. CCR4 expression may also account for frequent infiltration of ATL into tissues such as skin and lymph nodes...
  42. doi request reprint Autocrine and paracrine chemokine receptor 7 activation in head and neck cancer: implications for therapy
    Jun Wang
    Department of Otolaryngology, University of Pittsburgh Medical School, Pittsburgh, PA, USA
    J Natl Cancer Inst 100:502-12. 2008
    ..Constitutive prosurvival signaling by the phosphoinositide-3 kinase/Akt pathway has been observed in SCCHN cells independent of epidermal growth factor receptor (EGFR) signaling...
  43. ncbi request reprint Identification of cutaneous lymphocyte-associated antigen as sialyl 6-sulfo Lewis X, a selectin ligand expressed on a subset of skin-homing helper memory T cells
    Katsuyuki Ohmori
    Department of Clinical Pathology, Kyoto University School of Medicine, Japan
    Blood 107:3197-204. 2006
    ..We propose that CLA, which is expressed without any activation stimuli on peripheral skin-homing helper memory T cells in healthy persons, is at least partly the sialyl 6-sulfo Le(x) determinant...
  44. ncbi request reprint Skin irritants and contact sensitizers induce Langerhans cell migration and maturation at irritant concentration
    John J L Jacobs
    Department of Pathobiology, Utrecht University, Utrecht, The Netherlands
    Exp Dermatol 15:432-40. 2006
    ..In contrast, only allergenic compounds induced LC migration with partial maturation at subtoxic concentration. This effectively demonstrates that irritation is physiologically needed stimuli for inducing LC maturation...
  45. ncbi request reprint L-nitro-arginine inhibits increase in endothelin binding sites induced by ischemia and reperfusion
    Takashi Saito
    The 2nd Department of Internal Medicine, Akita University School of Medicine, 1 1 1 Hondo, Akita 010, Japan
    J Mol Cell Cardiol 34:1041-7. 2002
    ..01), but abolished either by LNA or SOD (P<0.01 and P<0.05, respectively). These results indicate that increase in ET-receptor by ischemia and reperfusion is mediated by free radicals generated via L-arginine to NO pathway...
  46. ncbi request reprint Pitavastatin inhibits upregulation of intermediate conductance calcium-activated potassium channels and coronary arteriolar remodeling induced by long-term blockade of nitric oxide synthesis
    Yutaka Terata
    Second Department of Internal Medicine, Akita University, Akita, Japan
    Pharmacology 68:169-76. 2003
    ..While in L+P group, rats received both LNAME and pitavastatin (PTV: 1 mg/kg/day in drinking water). Temporal profile of ImK mRNA was examined by RT-PCR using specific primers for ImK...
  47. ncbi request reprint [Primary Sjögren's syndrome with recurrent aseptic meningitis]
    Etsuko Matsubara
    The First Department of Internal Medicine, Ehime University School of Medicine
    Nihon Naika Gakkai Zasshi 95:1548-50. 2006
  48. ncbi request reprint Delayed recovery of effector memory CD4+ T cells by highly active antiretroviral therapy in a patient with HIV-1 infection
    Shinji Okada
    Department of Infectious and Respiratory Diseases, Tohoku University Graduate School of Medicine, Sendai, Japan
    Tohoku J Exp Med 196:213-8. 2002
    ..It suggests the possibility of delay in recovery of immune systems after the initiation of the therapy in HIV-1-infected patients, despite the prompt recovery of total CD4 + T cells...
  49. pmc CD151 regulates epithelial cell-cell adhesion through PKC- and Cdc42-dependent actin cytoskeletal reorganization
    Masaki Shigeta
    Institute for Protein Research, Osaka University, 3 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    J Cell Biol 163:165-76. 2003
    ..Together, these results indicate that CD151 is involved in epithelial cell-cell adhesion as a modulator of PKC- and Cdc42-dependent actin cytoskeletal reorganization...
  50. ncbi request reprint Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway
    Sathit Pichyangkul
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    J Immunol 172:4926-33. 2004
    ....
  51. pmc Potentiation of the ligand-binding activity of integrin alpha3beta1 via association with tetraspanin CD151
    Ryoko Nishiuchi
    Institute for Protein Research and Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565 0871, Japan
    Proc Natl Acad Sci U S A 102:1939-44. 2005
    ....