George Imataka

Summary

Affiliation: Dokkyo University School of Medicine
Country: Japan

Publications

  1. ncbi request reprint Brain hypothermia therapy for status epilepticus in childhood
    G Imataka
    Department of Pediatrics Dokkyo Medical University School of Medicine, Tochigi, Japan
    Eur Rev Med Pharmacol Sci 18:1883-8. 2014
  2. pmc Long-term, high-dose intravenous immunoglobulin therapy in a patient with banker-type juvenile dermatomyositis
    George Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi, 321 0293, Japan
    Cell Biochem Biophys 69:747-8. 2014
  3. pmc Better prognosis in newborns with trisomy 13 who received intensive treatments: a retrospective study of 16 patients
    Keiko Tsukada
    Department of Pediatrics, Dokkyo Medical University School of Medicine, Kitakobayashi 880, Mibu, Tochigi, 321 0293, Japan
    Cell Biochem Biophys 63:191-8. 2012
  4. ncbi request reprint Diagnosis of sex chromosomal abnormalities in neonatal intensive care units
    G Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, Tochigi, Japan
    Genet Couns 24:399-403. 2013
  5. pmc Autopsy report of a 7-year old patient with the mosaic trisomy 13
    George Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, 880 Mibu, Shimotsuga, Tochigi, 321 0293, Japan
    Cell Biochem Biophys 67:813-7. 2013
  6. pmc Novel c.2216T > C (p.I739T) mutation in exon 13 and c.1481T > A (p.L494X) mutation in exon 8 of MUT gene in a female with methylmalonic acidemia
    George Imataka
    Department of Pediatrics, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi, 321 0293, Japan
    Cell Biochem Biophys 67:185-7. 2013
  7. ncbi request reprint Partial epilepsy and developmental delay in infant with ring chromosome 14
    G Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, Tochigi, Japan
    Genet Couns 24:81-3. 2013
  8. ncbi request reprint Dandy-Walker syndrome and chromosomal abnormalities
    George Imataka
    Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan
    Congenit Anom (Kyoto) 47:113-8. 2007
  9. ncbi request reprint Survival of trisomy 18 cases in Japan
    G Imataka
    Department of Pediatrics, Dokkyo University School of Medicine, Japan
    Genet Couns 18:303-8. 2007
  10. pmc Chromosome analysis using spectral karyotyping (SKY)
    George Imataka
    Department of Pediatrics, Dokkyo Medical University, Shimotsuga, Tochigi, Japan
    Cell Biochem Biophys 62:13-7. 2012

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Brain hypothermia therapy for status epilepticus in childhood
    G Imataka
    Department of Pediatrics Dokkyo Medical University School of Medicine, Tochigi, Japan
    Eur Rev Med Pharmacol Sci 18:1883-8. 2014
    ..At the Dokkyo Medical University Hospital, we introduced a brain hypothermia therapy protocol for treating childhood status epilepticus and acute encephalitis/encephalopathy in 2004...
  2. pmc Long-term, high-dose intravenous immunoglobulin therapy in a patient with banker-type juvenile dermatomyositis
    George Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi, 321 0293, Japan
    Cell Biochem Biophys 69:747-8. 2014
    ..IVIg was administered every four weeks for six cycles thereafter, and the patient was able to walk more quickly with an improvement in quality of life. No apparent adverse effects were observed during IVIg treatment. ..
  3. pmc Better prognosis in newborns with trisomy 13 who received intensive treatments: a retrospective study of 16 patients
    Keiko Tsukada
    Department of Pediatrics, Dokkyo Medical University School of Medicine, Kitakobayashi 880, Mibu, Tochigi, 321 0293, Japan
    Cell Biochem Biophys 63:191-8. 2012
    ..This study provides useful information concerning genetic counseling, especially from an ethical point of view, before providing intensive management to newborns with trisomy 13...
  4. ncbi request reprint Diagnosis of sex chromosomal abnormalities in neonatal intensive care units
    G Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, Tochigi, Japan
    Genet Couns 24:399-403. 2013
    ..This seems to be due to the fact that sex chromosome abnormalities are likely to be clinically invisible in the NICU...
  5. pmc Autopsy report of a 7-year old patient with the mosaic trisomy 13
    George Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, 880 Mibu, Shimotsuga, Tochigi, 321 0293, Japan
    Cell Biochem Biophys 67:813-7. 2013
    ..These pathological changes have never previously been reported in the literature on trisomy 13, and the present patient is one of the oldest autopsied individuals with the mosaic trisomy 13. ..
  6. pmc Novel c.2216T > C (p.I739T) mutation in exon 13 and c.1481T > A (p.L494X) mutation in exon 8 of MUT gene in a female with methylmalonic acidemia
    George Imataka
    Department of Pediatrics, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi, 321 0293, Japan
    Cell Biochem Biophys 67:185-7. 2013
    ..Further tests on residual enzyme activity, as well as experience with more cases, may shed light on the relationship between gene mutations and phenotypes in MMA...
  7. ncbi request reprint Partial epilepsy and developmental delay in infant with ring chromosome 14
    G Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, Tochigi, Japan
    Genet Couns 24:81-3. 2013
    ..When refractory epilepsy is encountered in infancy with developmental delay of unknown cause, chromosome analysis should be performed...
  8. ncbi request reprint Dandy-Walker syndrome and chromosomal abnormalities
    George Imataka
    Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan
    Congenit Anom (Kyoto) 47:113-8. 2007
    ..There are various types of chromosomal abnormalities associated with DWS; most of them are reported in chromosome 3, 9, 13 and 18. We also summarize some other chromosomal abnormalities and various congenital malformation syndromes...
  9. ncbi request reprint Survival of trisomy 18 cases in Japan
    G Imataka
    Department of Pediatrics, Dokkyo University School of Medicine, Japan
    Genet Couns 18:303-8. 2007
    ..This evidence is valuable in order to perform genetic counseling concerning the natural history of trisomy 18 not only in Japan but also in other countries...
  10. pmc Chromosome analysis using spectral karyotyping (SKY)
    George Imataka
    Department of Pediatrics, Dokkyo Medical University, Shimotsuga, Tochigi, Japan
    Cell Biochem Biophys 62:13-7. 2012
    ..In this review, we will explain the principle of the spectral karyotyping, as well as its specificity and limitation in detecting the genetic defects within clinical application by presenting two case reports...
  11. ncbi request reprint Electroencephalography-guided resection of dysembryoplastic neuroepithelial tumor: case report
    George Imataka
    Department of Pediatrics, Dokkyo Medical University, Tochigi, Japan
    Neurol Med Chir (Tokyo) 48:318-21. 2008
    ..In this case, intraoperative electrocorticography was very useful to identify the possible focus and prevent unnecessary resection of the adjacent tissue. Total removal of the tumor resulted in a dramatic reduction of seizure activity...
  12. ncbi request reprint Down syndrome with acute epiglottitis
    George Imataka
    Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan
    Pediatr Int 47:333-5. 2005
  13. ncbi request reprint Callosal agenesis followed postnatally after prenatal diagnosis
    George Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan
    Congenit Anom (Kyoto) 46:160-2. 2006
    ..Here, we report the course of the case, and discuss the way prenatal ultrasonography should be used as a prenatal screening method, and the importance of counseling before the test...
  14. doi request reprint Drug-indiced aseptic meningitis: development of subacute sclerosing panencephalitis following repeated intraventricular infusion therapy with interferon alpha/beta
    George Imataka
    Department of Pediatrics, Dokkyo Medical University School of Medicine, Kitakobayashi 880, Mibu, Tochigi 321 0293, Japan
    Cell Biochem Biophys 61:699-701. 2011
    ..We, therefore, concluded that the longterm intraventricular IFN-α/β infusion therapy of SSPE involved the potential risk of DIAM with serious irreversible neurological sequelae and should be monitored carefully...
  15. ncbi request reprint An analysis of epilepsy with chromosomal abnormalities
    Hideo Yamanouchi
    Department of Pediatrics and Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi 321 0293, Japan
    Brain Dev 27:370-7. 2005
    ..One of the two patients with del(15)(q12)[Angelman syndrome] had giant-amplitude visual evoked potential, suggesting hyperexcitability of the visual cortex...
  16. ncbi request reprint [Long-term remission in an acute monoblastic leukemia patient with down syndrome after cord blood transplantation]
    Hidemitsu Kurosawa
    Department of Pediatrics, Dokkyo University School of Medicine
    Rinsho Ketsueki 46:274-7. 2005
    ..This patient remained well controlled in complete remission for 4 years, representing a rare case of DS with chemotherapy-resistant AML successfully treated with a CBT...
  17. doi request reprint Acute encephalopathy in children with Dravet syndrome
    Akihisa Okumura
    Department of Pediatrics, Juntendo University Faculty of Medicine, Bunkyo ku, Tokyo, Japan
    Epilepsia 53:79-86. 2012
    ..The occurrence of acute encephalopathy in children with Dravet syndrome has been reported sporadically. This study clarified the features of acute encephalopathy in children with Dravet syndrome...
  18. ncbi request reprint Reversible altered consciousness with brain atrophy caused by valproic acid
    Hideo Yamanouchi
    Department of Pediatrics, Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi 321 0293, Japan
    Pediatr Neurol 28:382-4. 2003
    ..Cerebral atrophy was nonexistent 2 months later. This rapidly developing but reversible alteration of consciousness in parallel with brain atrophy is recognized as a rare idiosyncratic adverse effect of valproic acid...
  19. ncbi request reprint Acute infantile encephalopathy predominantly affecting the frontal lobes
    Hideo Yamanouchi
    Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan
    Pediatr Neurol 34:93-100. 2006
    ..These unique features suggest that the frontal lobes are the focus of this novel subtype of acute encephalopathy, which we propose to call acute infantile encephalopathy predominantly affecting the frontal lobes...
  20. ncbi request reprint Chronic active Epstein-Barr virus infection with dilatation of the Valsalva sinus
    Yuya Sato
    Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan
    Pediatr Int 48:643-5. 2006
  21. ncbi request reprint X-linked thrombocytopenia in a girl
    Hirokazu Inoue
    Division of Haematology, Department of Paediatrics, Dokkyo University School of Medicine, Tochigi, Japan
    Br J Haematol 118:1163-5. 2002
    ..The X-inactivation analysis of the patients lymphocytes showed a random pattern of X-chromosome inactivation. To our knowledge, this is the first confirmed report of XLT in a female...
  22. ncbi request reprint Recurrent erythroblastopenia associated with Varicella zoster virus infection in an infant
    Takayuki Matsunaga
    Division of Hematology, Department of Pediatrics, Dokkyo University School of Medicine, Mibu, Japan
    Pediatr Int 45:355-8. 2003
  23. ncbi request reprint Congenital bilateral perisylvian syndrome associated with congenital constriction band syndrome
    Hideo Yamanouchi
    Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan
    J Child Neurol 17:448-50. 2002
    ..We believe that the combination of these two malfornative disorders was not coincidental; instead, fetal circulatory disturbance related to chronic abruptio placentae could account for this combination...
  24. ncbi request reprint Acute purulent meningitis associated with chronic subdural hematoma and subdural hygroma
    George Imataka
    Department of Pediatrics, Dokkyo Medical University Faculty of Medicine, Mibu, Shimotsuga, Tochigi, Japan
    Turk J Pediatr 49:437-40. 2007
    ....
  25. ncbi request reprint Ultrastructural and cytochemical characterization of human cord blood cells
    Tetsuya Mikami
    Department of Pediatrics, Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu machi, Tochigi 321 0293, Japan
    Med Electron Microsc 35:96-101. 2002
    ..We identified that cord blood cells were different from normal peripheral blood cells and bone marrow cells, confirming the functional differences that were previously assumed...
  26. ncbi request reprint gamma-Globulin-induced modulation with necrotic-like morphology of peripheral blood neutrophils
    Kenichi Sugita
    Department of Pediatrics, Dokkyo University School of Medicine, Mibu, Tochigi, Japan
    Eur J Pharmacol 513:141-4. 2005
    ..The modulatory effect of in vitro IgG was not observed in neutrophils from healthy volunteers and was significantly correlated with the antifebrile effect of in vivo IgG...
  27. ncbi request reprint [Mitochondrial diseases due to drug toxicity]
    Hideo Yamanouchi
    Department of Pediatrics, Dokkyo University School of Medicine
    Nihon Rinsho 60:473-7. 2002
  28. ncbi request reprint [Wolfram syndrome]
    George Imataka
    Department of Pediatrics, Dokkyo University School of Medicine
    Nihon Rinsho 60:466-8. 2002
  29. ncbi request reprint Anti-apoptotic effect of nerve growth factor is lost in congenital insensitivity to pain with anhidrosis (CIPA) B lymphocytes
    Yuya Sato
    Department of Pediatrics, Dokkyo University School of Medicine, Mibu, Tochigi, Japan
    J Clin Immunol 24:302-8. 2004
    ..We concluded that this phenomenon is one of the pathogeneses of CIPA...
  30. ncbi request reprint Expression of the N-methyl-D-aspartate receptor subunit R1 in the developing human hippocampus
    George Imataka
    Department of Pediatrics, Dokkyo University School of Medicine, Shimotsuga, Tochigi, Japan
    J Child Neurol 21:236-9. 2006
    ....
  31. ncbi request reprint [Coenzyme Q10 deficiency]
    George Imataka
    Department of Pediatrics, Dokkyo University School of Medicine
    Nihon Rinsho 60:462-5. 2002
  32. ncbi request reprint [Etiology and management of neonatal seizures--successful treatment by midazolam]
    Naoko Kawaguchi
    Department of Pediatrics, Dokkyo University School of Medicine, Shimotsuga Tochigi
    No To Hattatsu 38:5-9. 2006
    ..We consider that midazolam is effective and relatively safe for the management of neonatal seizures...
  33. ncbi request reprint Severe hyperbilirubinemia in a 10-year-old girl with a combined disorder of hereditary spherocytosis and Gilbert syndrome
    Kenichi Sugita
    Department of Pediatrics, Dokkyo University School of Medicine, Mibu, Tochigi, Japan
    Pediatr Int 49:540-2. 2007
  34. ncbi request reprint Suppressive effect of intravenous immunoglobulin on peripheral blood neutrophil count in patients with idiopathic thrombocytopenic purpura
    Kenichi Sugita
    Department of Pediatrics, Dokkyo University School of Medicine, Mibu, Tochigi, Japan
    J Pediatr Hematol Oncol 27:7-10. 2005
    ..To determine the effect of intravenous immunoglobulin (IVIG) on neutrophil count, the authors studied patients with idiopathic thrombocytopenic purpura (ITP)...
  35. doi request reprint Outcome of acute necrotizing encephalopathy in relation to treatment with corticosteroids and gammaglobulin
    Akihisa Okumura
    Department of Pediatrics, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Brain Dev 31:221-7. 2009
    ..To examine the relation between outcome and treatment with steroids and gammaglobulin in children with acute necrotizing encephalopathy...
  36. ncbi request reprint Fusion of an AF4-related gene, LAF4, to MLL in childhood acute lymphoblastic leukemia with t(2;11)(q11;q23)
    Mitsuteru Hiwatari
    Department of Pediatrics, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Oncogene 22:2851-5. 2003
    ..These findings suggest that LAF4, AF4 and AF5q31 might define a new family particularly involved in the pathogenesis of 11q23-associated ALL...
  37. ncbi request reprint Burkitt lymphoma associated with large gastric folds, pancreatic involvement, and biliary tract obstruction
    Hidemitsu Kurosawa
    Division of Hematology, Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan
    J Pediatr Hematol Oncol 24:310-2. 2002
    ..After completing 6 months of chemotherapy, the patient has been disease-free without neurologic complications for 2.5 years...
  38. ncbi request reprint [Lineage switch on recurrence from minimally differentiated acute leukemia (M0) to acute megakaryocytic leukemia (M7)]
    Yoshio Hatae
    Department of Pediatrics, Sapporo National Hospital
    Rinsho Ketsueki 43:543-7. 2002
    ..The patient simultaneously developed severe pneumonia and died in February, 1998. A lineage switch on relapse and resistance to chemotherapy may be associated with the occurrence of genetic aberration...