Kazufumi Akiyama

Summary

Affiliation: Dokkyo University School of Medicine
Country: Japan

Publications

  1. ncbi request reprint High plasma concentrations of paroxetine impede clinical response in patients with panic disorder
    Takashi Watanabe
    Department of Psychiatry, Dokkyo Medical University School of Medicine, Tochigi, Japan
    Ther Drug Monit 29:40-4. 2007
  2. doi request reprint Association of the Hermansky-Pudlak syndrome type 4 (HPS4) gene variants with cognitive function in patients with schizophrenia and healthy subjects
    Go Kuratomi
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi 3210293, Japan
    BMC Psychiatry 13:276. 2013
  3. doi request reprint Chronic methamphetamine psychosis after long-term abstinence in Japanese incarcerated patients
    Kazufumi Akiyama
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, Japan
    Am J Addict 20:240-9. 2011
  4. doi request reprint mRNA expression of the Nurr1 and NGFI-B nuclear receptor families following acute and chronic administration of methamphetamine
    Kazufumi Akiyama
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321 0293, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:1957-66. 2008
  5. ncbi request reprint mRNA expression of activity-regulated cytoskeleton-associated protein (arc) in the amygdala-kindled rats
    Kazufumi Akiyama
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, Japan
    Brain Res 1189:236-46. 2008
  6. ncbi request reprint Longitudinal clinical course following pharmacological treatment of methamphetamine psychosis which persists after long-term abstinence
    Kazufumi Akiyama
    Department of Psychiatry, Dokkyo Medical University School of Medicine, Kitakobayashi 880, Mibu, Tochigi 00 321 0293, Japan
    Ann N Y Acad Sci 1074:125-34. 2006
  7. doi request reprint Genetic and pharmacokinetic factors affecting the initial pharmacotherapeutic effect of paroxetine in Japanese patients with panic disorder
    Yoshinori Saeki
    Department of Psychiatry, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu machi, Shimotsuga, Tochigi, 321 0293, Japan
    Eur J Clin Pharmacol 65:685-91. 2009
  8. doi request reprint Determinants of pharmacodynamic trajectory of the therapeutic response to paroxetine in Japanese patients with panic disorder
    Shin Ishiguro
    Department of Psychiatry, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu machi, Shimotsuga, Tochigi 321 0293, Japan
    Eur J Clin Pharmacol 67:1213-21. 2011
  9. doi request reprint An association study on polymorphisms in the PEA15, ENTPD4, and GAS2L1 genes and schizophrenia
    Atsushi Saito
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Japan
    Psychiatry Res 185:9-15. 2011
  10. doi request reprint An association study of the Hermansky-Pudlak syndrome type 4 gene in schizophrenic patients
    Atsushi Saito
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, Mibu, Tochigi 321 0293, Japan
    Psychiatr Genet 23:163-73. 2013

Collaborators

Detail Information

Publications13

  1. ncbi request reprint High plasma concentrations of paroxetine impede clinical response in patients with panic disorder
    Takashi Watanabe
    Department of Psychiatry, Dokkyo Medical University School of Medicine, Tochigi, Japan
    Ther Drug Monit 29:40-4. 2007
    ..2 in the equation above, plasma concentration of paroxetine is calculated to be about 25 ng/mL, which is suggested to be the upper end of the therapeutic window for the initial phase of the treatment with paroxetine for panic disorder...
  2. doi request reprint Association of the Hermansky-Pudlak syndrome type 4 (HPS4) gene variants with cognitive function in patients with schizophrenia and healthy subjects
    Go Kuratomi
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi 3210293, Japan
    BMC Psychiatry 13:276. 2013
    ..The purpose of the present study was to investigate whether HPS4 is associated with cognitive functions in patients with schizophrenia and healthy controls and with the clinical profiles of patients with schizophrenia...
  3. doi request reprint Chronic methamphetamine psychosis after long-term abstinence in Japanese incarcerated patients
    Kazufumi Akiyama
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, Japan
    Am J Addict 20:240-9. 2011
    ..The present study provides evidence that a subpopulation of Meth abusers suffered from chronic Meth psychosis in long-term abstinence, and also highlights the involvement of affective symptoms in its severity. ..
  4. doi request reprint mRNA expression of the Nurr1 and NGFI-B nuclear receptor families following acute and chronic administration of methamphetamine
    Kazufumi Akiyama
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321 0293, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:1957-66. 2008
    ..These results suggest that Nurr1 and NGFI-B mRNA play differential roles upon exposure to METH...
  5. ncbi request reprint mRNA expression of activity-regulated cytoskeleton-associated protein (arc) in the amygdala-kindled rats
    Kazufumi Akiyama
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, Japan
    Brain Res 1189:236-46. 2008
    ..These results support that arc serves as an effector IEG whose mRNA is associated with synaptic reorganization in kindling...
  6. ncbi request reprint Longitudinal clinical course following pharmacological treatment of methamphetamine psychosis which persists after long-term abstinence
    Kazufumi Akiyama
    Department of Psychiatry, Dokkyo Medical University School of Medicine, Kitakobayashi 880, Mibu, Tochigi 00 321 0293, Japan
    Ann N Y Acad Sci 1074:125-34. 2006
    ..These results suggest that both psychotic and affective symptoms are involved in therapeutic response and prognosis of METH psychosis...
  7. doi request reprint Genetic and pharmacokinetic factors affecting the initial pharmacotherapeutic effect of paroxetine in Japanese patients with panic disorder
    Yoshinori Saeki
    Department of Psychiatry, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu machi, Shimotsuga, Tochigi, 321 0293, Japan
    Eur J Clin Pharmacol 65:685-91. 2009
    ..The objective of this study was to evaluate genetic and pharmacokinetic factors affecting the initial pharmacotherapeutic effect of paroxetine (PAX) in Japanese patients with panic disorder (PD)...
  8. doi request reprint Determinants of pharmacodynamic trajectory of the therapeutic response to paroxetine in Japanese patients with panic disorder
    Shin Ishiguro
    Department of Psychiatry, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu machi, Shimotsuga, Tochigi 321 0293, Japan
    Eur J Clin Pharmacol 67:1213-21. 2011
    ..The objective of this study was to evaluate genetic and pharmacokinetic factors to establish the pharmacotherapeutic effect of paroxetine (PAX) in patients with panic disorder (PD)...
  9. doi request reprint An association study on polymorphisms in the PEA15, ENTPD4, and GAS2L1 genes and schizophrenia
    Atsushi Saito
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Japan
    Psychiatry Res 185:9-15. 2011
    ..The present study fails to provide evidence for the contribution of PEA15, ENTPD4, and GAS2L1 genes to the etiology of schizophrenia in the Japanese population...
  10. doi request reprint An association study of the Hermansky-Pudlak syndrome type 4 gene in schizophrenic patients
    Atsushi Saito
    Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, Mibu, Tochigi 321 0293, Japan
    Psychiatr Genet 23:163-73. 2013
    ....
  11. ncbi request reprint The impact of CYP2D6 genotypes on the plasma concentration of paroxetine in Japanese psychiatric patients
    Mikito Ueda
    Department of Psychiatry, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520 2192, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 30:486-91. 2006
    ..The present results suggest that having one non-functional allele is the marker for high plasma concentration of PAX when relatively high daily dose of PAX is administered...
  12. ncbi request reprint Association study of putative promoter polymorphisms in the neuroplastin gene and schizophrenia
    Atsushi Saito
    Department of Psychiatry, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
    Neurosci Lett 411:168-73. 2007
    ..These results suggest that NPTN may be involved in genetic susceptibility to schizophrenia...
  13. ncbi request reprint Effect of acute and chronic treatment with methamphetamine on mRNA expression of synaptotagmin IV and 25 KDa-synaptic-associated protein in the rat brain
    Taketo Isao
    Department of Psychiatry, Dokkyo University School of Medicine, Tochigi, Japan
    Psychiatry Clin Neurosci 58:410-9. 2004
    ..The results of the present study suggest that SytIV may play an important role in the synaptic plasticity underlying METH-induced neuroadaptive changes including behavioral sensitization...