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Affiliation: Daiichi Sankyo Co
Uto Y. Imidazo[1,2-a]pyridines as cholesterol 24-hydroxylase (CYP46A1) inhibitors: a patent evaluation (WO2014061676). Expert Opin Ther Pat. 2015;25:373-7 pubmed publisher
..These compounds represent a novel pharmacophore that is different from other structural motifs described in the prior patent publications by Takeda Pharmaceutical Company Ltd. ..
Uto Y. 1,2-Benzisoxazole compounds: a patent review (2009 - 2014). Expert Opin Ther Pat. 2015;25:643-62 pubmed publisher
..It is fair to assume that the wide and frequent use of benzisoxazoles in drug discovery and development will continue into the future. ..
Uto Y. Recent progress in the discovery and development of stearoyl CoA desaturase inhibitors. Chem Phys Lipids. 2016;197:3-12 pubmed publisher
..This review aims to summarize the examples of the recently reported novel SCD1 inhibitors and to highlight the emerging areas of target indications that may hold promise for the development of SCD1 inhibitors. ..
Uto Y. 1, 2-Benzisoxazole: A Privileged Structure with a Potential for Polypharmacology. Curr Pharm Des. 2016;22:3201-11 pubmed