Y Yamada

Summary

Affiliation: Chugai Pharmaceutical Co
Country: Japan

Publications

  1. ncbi request reprint Molecular cloning of a novel vascular endothelial growth factor, VEGF-D
    Y Yamada
    Gene Search Program, Chugai Research Institute for Molecular Medicine, Niihari, Ibaraki, Japan
    Genomics 42:483-8. 1997
  2. ncbi request reprint Cloning, characterization, and expression analysis of mouse enamelysin
    J Caterina
    Matrix Metalloproteinase Unit, National Institute of Dental and Craniofacial Research, Bethesda, MD 20892 4380, USA
    J Dent Res 79:1697-703. 2000
  3. ncbi request reprint Molecular diversity and functional characterization of voltage-dependent calcium channels (CACN4) expressed in pancreatic beta-cells
    Y Ihara
    Department of Metabolism and Clinical Nutrition Kyoto University Faculty of Medicine, Japan
    Mol Endocrinol 9:121-30. 1995
  4. ncbi request reprint Cloning and expression of laminin alpha 2 chain (M-chain) in the mouse
    S M Bernier
    Laboratory of Development of Biology, National Institute of Dental Research, Bethesda, Maryland, USA
    Matrix Biol 14:447-55. 1995
  5. ncbi request reprint Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter
    Y Aihara
    Laboratory of Molecular Genetics, Department of Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Gunma, Japan
    J Neurochem 74:2622-5. 2000
  6. ncbi request reprint Molecular characterization of the S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase involved in isoquinoline alkaloid biosynthesis in Coptis japonica
    T Morishige
    Division of Applied Life Science, Graduate School of Agriculture, Kyoto University, Kyoto 606 8502, Japan
    J Biol Chem 275:23398-405. 2000
  7. ncbi request reprint Cloning, genomic organization and chromosomal assignment of the mouse p190-B gene
    P D Burbelo
    Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC 20007
    Biochim Biophys Acta 1443:203-10. 1998
  8. ncbi request reprint Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype
    Y Yamada
    Department of Metabolism and Clinical Nutrition, Kyoto University Faculty of Medicine, Japan
    Biochem Biophys Res Commun 195:844-52. 1993
  9. ncbi request reprint Human gastric inhibitory polypeptide receptor: cloning of the gene (GIPR) and cDNA
    Y Yamada
    Department of Metabolism and Clinical Nutrition, Kyoto University Faculty of Medicine, Japan
    Genomics 29:773-6. 1995
  10. ncbi request reprint Molecular cloning of a novel receptor-type protein tyrosine phosphatase from murine fetal liver
    T Yoneya
    Pharmaceutical Research Laboratory, Kirin Brewery Co Ltd, Gunma, Japan
    Gene 194:241-7. 1997

Collaborators

Detail Information

Publications62

  1. ncbi request reprint Molecular cloning of a novel vascular endothelial growth factor, VEGF-D
    Y Yamada
    Gene Search Program, Chugai Research Institute for Molecular Medicine, Niihari, Ibaraki, Japan
    Genomics 42:483-8. 1997
    ..The high level of conservation between mouse and human VEGF-D may emphasize the biological importance of this gene. Recently the murine gene, FIGF, which is identical to mouse VEGF-D, was reported...
  2. ncbi request reprint Cloning, characterization, and expression analysis of mouse enamelysin
    J Caterina
    Matrix Metalloproteinase Unit, National Institute of Dental and Craniofacial Research, Bethesda, MD 20892 4380, USA
    J Dent Res 79:1697-703. 2000
    ..Characterization of mouse enamelysin demonstrated that it is highly conserved in both its sequence content and pattern of expression relative to the porcine, human, and bovine homologues previously described...
  3. ncbi request reprint Molecular diversity and functional characterization of voltage-dependent calcium channels (CACN4) expressed in pancreatic beta-cells
    Y Ihara
    Department of Metabolism and Clinical Nutrition Kyoto University Faculty of Medicine, Japan
    Mol Endocrinol 9:121-30. 1995
    ..Furthermore, the present study suggests that the expression of the beta-subunit as well as the alpha 1-subunit may participate in the regulation of insulin secretion...
  4. ncbi request reprint Cloning and expression of laminin alpha 2 chain (M-chain) in the mouse
    S M Bernier
    Laboratory of Development of Biology, National Institute of Dental Research, Bethesda, Maryland, USA
    Matrix Biol 14:447-55. 1995
    ....
  5. ncbi request reprint Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter
    Y Aihara
    Laboratory of Molecular Genetics, Department of Cell Biology, Institute for Molecular and Cellular Regulation, Gunma University, Gunma, Japan
    J Neurochem 74:2622-5. 2000
    ..These results indicate that BNPI and DNPI, which coordinate Na(+)-dependent P(i) transport in the neuron-rich regions of the brain, may form a new class within the Na(+)/P(i) cotransporter family...
  6. ncbi request reprint Molecular characterization of the S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase involved in isoquinoline alkaloid biosynthesis in Coptis japonica
    T Morishige
    Division of Applied Life Science, Graduate School of Agriculture, Kyoto University, Kyoto 606 8502, Japan
    J Biol Chem 275:23398-405. 2000
    ..The molecular evolution of these two related O-methyltransferases is discussed...
  7. ncbi request reprint Cloning, genomic organization and chromosomal assignment of the mouse p190-B gene
    P D Burbelo
    Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC 20007
    Biochim Biophys Acta 1443:203-10. 1998
    ..The high level of sequence homology between the human and the mouse suggests that there is a strong selective pressure to maintain the p190-B protein structure...
  8. ncbi request reprint Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype
    Y Yamada
    Department of Metabolism and Clinical Nutrition, Kyoto University Faculty of Medicine, Japan
    Biochem Biophys Res Commun 195:844-52. 1993
    ..These results suggest that diverse actions of somatostatin are mediated by at least five somatostatin receptor subtypes with potentially different function...
  9. ncbi request reprint Human gastric inhibitory polypeptide receptor: cloning of the gene (GIPR) and cDNA
    Y Yamada
    Department of Metabolism and Clinical Nutrition, Kyoto University Faculty of Medicine, Japan
    Genomics 29:773-6. 1995
    ..The human GIPR gene is about 13.8 kb long, consists of 14 exons, and carries 17 Alu repeats...
  10. ncbi request reprint Molecular cloning of a novel receptor-type protein tyrosine phosphatase from murine fetal liver
    T Yoneya
    Pharmaceutical Research Laboratory, Kirin Brewery Co Ltd, Gunma, Japan
    Gene 194:241-7. 1997
    ..7 kb, and these transcripts were expressed in a tissue-specific manner. During embryogenesis, only the 6-kb transcript was detected...
  11. ncbi request reprint Role of FK506-binding protein 12 in development of the chick embryonic heart
    K Obata
    United Graduate School of Agricultural Science, Gifu University, Gifu, Japan
    Biochem Biophys Res Commun 283:613-20. 2001
    ..These results suggest that FKBP12 is important in the regulation of contractile function and phenotypic expression in chick cardiomyocytes during embryonic development...
  12. ncbi request reprint Molecular cloning of delta-4, a new mouse and human Notch ligand
    T Yoneya
    Pharmaceutical Research Laboratory, Kirin Brewery Co Ltd, Miyahara, Takasaki, Gunma 370 1295, Japan
    J Biochem 129:27-34. 2001
    ..Soluble forms of the extracellular portion of Delta-4 inhibit the apparent proliferation of human aortic endothelial cells, but not human pulmonary arterial endothelial cells...
  13. ncbi request reprint Molecular cloning and partial characterization of a novel collagen chain, alpha 1(XVI), consisting of repetitive collagenous domains and cysteine-containing non-collagenous segments
    N Yamaguchi
    Department of Tissue Physiology, Tokyo Medical and Dental University
    J Biochem 112:856-63. 1992
    ..The gene of alpha 1(XVI) chain, COL16A1, is mapped on the short arm of human chromosome 1 (1p13-p34)...
  14. ncbi request reprint Cloning of a functional splice variant of L-type calcium channel beta 2 subunit from rat heart
    Y Yamada
    Department of Cellular Physiology and Signal Transduction, Sapporo Medical University School of Medicine, Sapporo 060 8556, Japan
    J Biol Chem 276:47163-70. 2001
    ..Taken together, these observations suggest that the beta(2c) subunit is a functional beta(2) subunit expressed in heart and that the short N-terminal region plays a major role in modifying inactivation kinetics...
  15. ncbi request reprint Vascular endothelial growth factor and cellular chemotaxis: a possible autocrine pathway in adult T-cell leukemia cell invasion
    T Hayashibara
    Department of Haematology, Molecular Medicine Unit, Atomic Disease Institute, Nagasaki University School of Medicine, Japan
    Clin Cancer Res 7:2719-26. 2001
    ..Collectively, these data lead us to propose a possible autocrine mechanism involving VEGF operating by way of Flt-1, in which ATL cells up-regulate their own chemotaxis to facilitate their invasion into various organs...
  16. ncbi request reprint Exogenous clustered neuropilin 1 enhances vasculogenesis and angiogenesis
    Y Yamada
    Department of Cell Differentiation, Institute of Molecular Embryology and Genetics, University School of Medicine, Kumamoto, Japan
    Blood 97:1671-8. 2001
    ..Moreover, NP-1-Fc rescued the defective vascularity of np-1(-/-) embryos in vivo. These results suggest that a dimer form of soluble NP-1 delivers VEGF165 to VEGFR-2-positive endothelial cells and promotes angiogenesis...
  17. pmc The alpha chain of laminin-1 is independently secreted and drives secretion of its beta- and gamma-chain partners
    P D Yurchenco
    Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
    Proc Natl Acad Sci U S A 94:10189-94. 1997
    ..Such an alpha-chain-dependent mechanism could allow for the regulation of laminin export into a nascent basement membrane, and might serve an important role in controlling basement membrane formation...
  18. pmc Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion
    K Honda
    Pathology Division, National Cancer Center Research Institute, Tokyo 104, Japan
    J Cell Biol 140:1383-93. 1998
    ..These findings suggest that cytoplasmic actinin-4 regulates the actin cytoskeleton and increases cellular motility and that its inactivation by transfer to the nucleus abolishes the metastatic potential of human cancers...
  19. ncbi request reprint Bio-kinetics of radon ingested from drinking water
    T Ishikawa
    Radon Research Group, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba, 263 8555, Japan
    Radiat Prot Dosimetry 105:65-70. 2003
    ..The present results, however, suggest that a part of radon stayed longer in the stomach than expected in the previous models...
  20. ncbi request reprint Analysis of cDNAs from a mouse embryo tooth library: identification of novel genes during tooth development
    F J Unda
    Department of Cell Biology, Faculty of Medicine and Dentistry, University of the Basque Country, Leioa 48940, Vizcaya, Spain
    Connect Tissue Res 43:176-9. 2002
    ..5 mouse molars. In this work, we report the partial cDNA sequences of 10 noncharacterized genes and we show cell expression of the transcripts on mouse embryo molars by in situ hybridization...
  21. ncbi request reprint Disrupted expression of matrix genes in the growth plate of the mouse cartilage matrix deficiency (cmd) mutant
    A W Wai
    Department of Biochemistry, University of Hong Kong, China
    Dev Genet 22:349-58. 1998
    ..The discordance of gene expression in cmd chondrocytes may be additional factors contributing to the disrupted cellular architecture of the growth plate resulting from the primary absence of aggrecan...
  22. ncbi request reprint The alpha4bbeta7-integrin is dynamically expressed on murine eosinophils and involved in eosinophil trafficking to the intestine
    E B Brandt
    Division of Allergy and Immunology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Clin Exp Allergy 36:543-53. 2006
    ..Most studies have focused on the role of the alpha4beta1-adhesion complex, but eosinophils also express the alpha4beta7-integrin complex...
  23. ncbi request reprint Changes in cortical and cerebellar bcl-2 mRNA levels in the developing hydrocephalic rat (LEW-HYR) as measured by a real time quantified RT-PCR
    Y Yamada
    Department of Neurosurgery, Tokyo Medical University, 6 7 1 Nishi shinjuku, Shinjuku ku, Tokyo 160 0023, Japan
    Neuroscience 114:165-71. 2002
    ....
  24. ncbi request reprint Spatiotemporal, allelic, and enforced expression of Ximpact, the Xenopus homolog of mouse imprinted gene impact
    Y Yamada
    Human Genome Center, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Tokyo, Minato ku, 108 8639, Japan
    Biochem Biophys Res Commun 256:162-9. 1999
    ..Overexpression of Ximpact by RNA microinjection resulted in a higher than normal rate of gastrulation defects, suggesting the need for tight control of its dosage in early development...
  25. ncbi request reprint Identification of a novel promoter and exons of the c-ERBB-2 gene
    M Nezu
    Genetics Division, National Cancer Center Research Institute, 1 1, Tsukiji 5 chome, Chuo Ku, Tokyo, 104 0045, Japan
    Biochem Biophys Res Commun 258:499-505. 1999
    ..Although the presence of the predicted protein product was not examined, this report is important in that it provides a new aspect of the c-ERBB-2 protooncogene products...
  26. pmc Failure of ureteric bud invasion: a new model of renal agenesis in mice
    T Kamba
    Department of Pathology and Biology of Diseases, Kyoto University Graduate School of Medicine, Kyoto Saitama, Japan
    Am J Pathol 159:2347-53. 2001
    ..Studies of fubi1 congenic mice indicated that interaction of two or more loci is essential for the FUBI phenotype...
  27. pmc A zinc finger transcription factor, alphaA-crystallin binding protein 1, is a negative regulator of the chondrocyte-specific enhancer of the alpha1(II) collagen gene
    K Tanaka
    Craniofacial Developmental Biology and Regeneration Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mol Cell Biol 20:4428-35. 2000
    ..Cotransfection of CRYBP1 with Sox9 into BALB/c 3T3 cells inhibited activation of the Col2a1 enhancer by Sox9. These results suggest a novel mechanism that negatively regulates cartilage-specific expression of Col2a1...
  28. ncbi request reprint Cloning, characterization and immunolocalization of human ameloblastin
    M MacDougall
    University of Texas Health Science Center at San Antonio, Dental School, 78229 3900, USA
    Eur J Oral Sci 108:303-10. 2000
    ..Immunohistochemistry studies on embryonic human teeth using an antibody to recombinant ameloblastin indicated ameloblastin expression by ameloblasts with localization in the enamel matrix associated with the sheath structures...
  29. ncbi request reprint Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase family
    N Shiraishi
    Tokyo Research Laboratories, Kyowa Hakko Kogyo Company, Limited, 3 6 6 Asahi machi, Machida shi, Tokyo 194 8533, Japan
    J Biol Chem 276:3498-507. 2001
    ..Considering the differences in substrate specificity and distribution, each beta1,3-N-acetylglucosaminyltransferase may play different roles...
  30. ncbi request reprint Multiple variants of receptor-type protein tyrosine phosphatase beta are expressed in the central nervous system of Xenopus
    S Nagata
    Department of Chemical and Biological Sciences, Faculty of Science, Japan Women s University, 112 8681, Tokyo, Japan
    Gene 262:81-8. 2001
    ..The results of these as well as reverse-transcribed polymerase chain reaction analyses suggest that the amounts of different XRPTPbeta variants are regulated in tissue- and developmental stage-specific manners...
  31. ncbi request reprint Identification and characterization of a cDNA for mouse ameloblastin
    D Simmons
    University of Texas Health Science Center at San Antonio, Dental School, USA
    Connect Tissue Res 39:3-12; discussion 63-7. 1998
    ..Reverse transcriptase-PCR analysis using mouse first and second mandibular molar mRNA indicated initial expression at E-14. This is one day after the initial expression of tuftelin (E-13) and one day prior to that of amelogenin (E-15)...
  32. ncbi request reprint Highly potent nociceptin analog containing the Arg-Lys triple repeat
    K Okada
    Laboratory of Structure Function Biochemistry, Kyushu University, Fukuoka, 812 8581, Japan
    Biochem Biophys Res Commun 278:493-8. 2000
    ....
  33. pmc Metabolic engineering of plant alkaloid biosynthesis
    F Sato
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan
    Proc Natl Acad Sci U S A 98:367-72. 2001
    ..Ectopic expression of SMT caused the accumulation of benzylisoquinoline alkaloids in E. californica. The prospects and limitations of engineering plant alkaloid metabolism are discussed...
  34. ncbi request reprint Two dominant host resistance genes to pre-B lymphoma in wild-derived inbred mouse strain MSM/Ms
    A Pataer
    Department of Pathology and Biology of Disease, Graduate School of Medicine, Japan
    Cancer Res 56:3716-20. 1996
    ..0). All 13 pre-B lymphoma-bearing backcross mice were homozygous for SL/Kh-derived alleles at these loci. We named the gene on chromosome 17 Msmr1 (for MSM resistance 1) and that on chromosome 18 Msmr 2 (for MSM resistance 2)...
  35. ncbi request reprint Gene organization in the ada-rplL region of Streptomyces virginiae
    M Katayama
    Department of Biotechnology, Faculty of Engineering, Osaka University, Japan
    Gene 171:135-6. 1996
    ..Six of the ORFs (secE-rplL) were oriented in the same direction, but the other two (ada and aat) had the opposite orientation. The gene organization of the secE-rplL region in Sv was identical to that in Escherichia coli...
  36. pmc Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats
    M Sasaki
    Proc Natl Acad Sci U S A 84:935-9. 1987
    ..Part of the cysteine-rich region is homologous to epidermal growth factor and other proteins that contain epidermal growth factor-like repeats...
  37. ncbi request reprint Structure of the amino-terminal portion of the murine alpha 1(IV) collagen chain and the corresponding region of the gene
    P D Killen
    Laboratory of Developmental Biology and Anomalies, National Institute of Dental Research, Bethesda, Maryland 20892
    J Biol Chem 263:8706-9. 1988
    ..The exon structure for the helical portion of the 7 S domain is different from that of the major helical domain, suggesting that they evolved differently...
  38. pmc Osteonectin mRNA: distribution in normal and transformed cells
    M F Young
    Nucleic Acids Res 14:4483-97. 1986
    ..The level of osteonectin mRNA was drastically decreased in chick embryo fibroblasts transformed by Rous sarcoma virus...
  39. ncbi request reprint Alpha 1 type IV collagen gene evolved differently from fibrillar collagen genes
    Y Sakurai
    J Biol Chem 261:6654-7. 1986
    ..These sizes do not appear to be related to the 54-base pair coding unit which is characteristic of fibrillar collagen exons, suggesting that the alpha 1 type IV collagen gene evolved differently from the fibrillar collagen genes...
  40. ncbi request reprint Isolation and partial characterization of genomic clones coding for a human pro-alpha 1 (II) collagen chain and demonstration of restriction fragment length polymorphism at the 3' end of the gene
    A M Nunez
    Biochemistry 24:6343-8. 1985
    ..5-kb RNA for the rat type II procollagen chain. Finally, studies of genomic DNAs from normal individuals reveal the presence of a HindIII and a BamHI polymorphic site at the 3' end of the gene...
  41. ncbi request reprint Identification of cDNA clones encoding different domains of the basement membrane heparan sulfate proteoglycan
    D M Noonan
    Laboratory of Developmental Biology and Anomalies, National Institute of Dental Research, Bethesda, Maryland 20892
    J Biol Chem 263:16379-87. 1988
    ..The sequence DSGEY was found four times in this domain and could be heparan sulfate attachment sites...
  42. ncbi request reprint Gastric inhibitory polypeptide: structure and chromosomal localization of the human gene
    N Inagaki
    Department of Medicine, Kyoto University School of Medicine, Japan
    Mol Endocrinol 3:1014-21. 1989
    ..The promoter region of the human GIP gene contains potential binding sites for a number of transcriptional factors including Sp 1, AP-1, and AP-2. The human GIP gene has been assigned to chromosome 17q21.3----q22...
  43. ncbi request reprint Amino acid sequence of the non-collagenous globular domain (NC1) of the alpha 1(IV) chain of basement membrane collagen as derived from complementary DNA
    I Oberbäumer
    Eur J Biochem 147:217-24. 1985
    ..These DNA and protein sequences are compared to the corresponding sequences of other collagens and discussed with respect to their structural and biological significance...
  44. pmc Characterization of the promoter for the rat and human link protein gene
    C Rhodes
    Laboratory of Developmental Biology, National Institute of Dental Research, National Institutes of Health, Bethesda, MD 20892
    Nucleic Acids Res 19:1933-9. 1991
    ..These results indicate the presence of positive cisacting regulatory elements in both the promoter and first intron of the rat gene for link protein...
  45. ncbi request reprint The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule
    D M Noonan
    Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy
    J Biol Chem 266:22939-47. 1991
    ..The variety of domains in perlecan suggest multiple interactions with other molecules...
  46. pmc Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney
    Y Yamada
    Department of Biochemistry and Molecular Biology, University of Chicago, IL 60637
    Proc Natl Acad Sci U S A 89:251-5. 1992
    ..Thus, the biological effects of somatostatin are mediated by a family of receptors that are expressed in a tissue-specific manner...
  47. ncbi request reprint Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase
    Y Yamada
    Department of Metabolism and Clinical Nutrition, Kyoto University Faculty of Medicine, Japan
    Mol Endocrinol 6:2136-42. 1992
    ..These results indicate that the diverse biological effects of somatostatin are mediated by a family of receptor with distinct, but overlapping, tissue distributions, unique pharmacological properties, and potentially different functions...
  48. ncbi request reprint Isolation and characterization of a genomic clone encoding chick alpha 1 type III collagen
    Y Yamada
    J Biol Chem 258:2758-61. 1983
    ..R-loop electron microscopic analysis indicates that at least 16 exons are interspersed in a 9-kilobase DNA segment that contains the third distal part of the alpha 1 type III collagen gene...
  49. ncbi request reprint Identification of genomic DNA coding for chicken type II procollagen
    L J Sandell
    J Biol Chem 258:11617-21. 1983
    ..This region of the chicken alpha 1 (type II) procollagen gene is encoded within a shorter segment of the chicken genome than is the corresponding region of the alpha 2(type I) procollagen gene...
  50. ncbi request reprint Full-length sequence, localization, and chromosomal mapping of ameloblastin. A novel tooth-specific gene
    P H Krebsbach
    Laboratory of Developmental Biology, NIDR and the Laboratory of Molecular Microbiology, NIAID, National Institutes of Health, Bethesda, Maryland 20892 4370, USA
    J Biol Chem 271:4431-5. 1996
    ..Thus, ameloblastin represents a unique ameloblast-specific gene product that may be important in enamel matrix formation and mineralization...
  51. ncbi request reprint p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking
    P D Burbelo
    Laboratory of Developmental Biology, NIDR, National Institutes of Health, Bethesda, Maryland 20892 4370, USA
    J Biol Chem 270:30919-26. 1995
    ..These results identify a novel second member of the p190 family and establish the existence of a novel transmembrane link between integrins and a new protein p190-B and Rho...
  52. ncbi request reprint Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms
    Y Yamada
    Howard Hughes Medical Institute, University of Chicago, Illinois 60637
    Genomics 15:449-52. 1993
    ..1, respectively. Highly informative simple tandem repeat DNA polymorphisms were identified in SSTR1 and SSTR2...
  53. pmc Cloning of the large subunit of activator 1 (replication factor C) reveals homology with bacterial DNA ligases
    P D Burbelo
    Laboratory of Developmental Biology, National Institute of Dental Research, National Institutes of Health, Bethesda, MD 20892
    Proc Natl Acad Sci U S A 90:11543-7. 1993
    ..The finding that the region required for the binding of murine A1 p145 to DNA has similarity to a domain found in DNA ligases suggests that this region may be utilized by both proteins in recognizing DNA...
  54. ncbi request reprint Deficiency of merosin in dystrophic dy mice and genetic linkage of laminin M chain gene to dy locus
    Y Sunada
    Howard Hughes Medical Institute, University of Iowa College of Medicine, Iowa City 52242
    J Biol Chem 269:13729-32. 1994
    ....
  55. ncbi request reprint A cloned rat CD38-homologous protein and its expression in pancreatic islets
    Q Li
    Department of Metabolism and Clinical Nutrition, Kyoto University Faculty of Medicine, Japan
    Biochem Biophys Res Commun 202:629-36. 1994
    ..The presence of rat CD38H in the pancreatic islets suggests that CD38H may be involved in insulin secretion by synthesizing cADP-ribose...
  56. ncbi request reprint Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures
    A Utani
    Laboratory of Developmental Biology, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892
    J Biol Chem 269:19167-75. 1994
    ..These results suggest that distinct sites within the C-terminal alpha-helical region of the laminin long arm are critical for the chain-specific assembly of these macro-molecules...
  57. ncbi request reprint A new type of defect in the gene for bilirubin uridine 5'-diphosphate-glucuronosyltransferase in a patient with Crigler-Najjar syndrome type I
    S Aono
    Department of Perinatology, Institute for Developmental Research, Aichi Prefecture Colony, Japan
    Pediatr Res 35:629-32. 1994
    ..Our results suggest that a homozygous nonsense or deletion mutation is detected not only in the exons common to UGT1A and UGT1D genes but also in unique exon 1 of UGT1A in CN type I...
  58. ncbi request reprint Mouse cartilage matrix deficiency (cmd) caused by a 7 bp deletion in the aggrecan gene
    H Watanabe
    Laboratory of Developmental Biology, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892
    Nat Genet 7:154-7. 1994
    ..DNA sequencing of the aggrecan gene identified a 7 bp deletion in exon 5 resulting in a severely truncated molecule. The finding of an aggrecan mutation in the cmd mouse confirms the critical role of aggrecan in cartilage formation...
  59. ncbi request reprint Cloning and expression of the mouse laminin gamma 2 (B2t) chain, a subunit of epithelial cell laminin
    S Sugiyama
    Laboratory of Developmental Biology, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892
    Eur J Biochem 228:120-8. 1995
    ..This protein complex is characteristic of the kalinin (nicein/epiligrin) complex, and provides further evidence that these proteins are identical and that the gamma 2 chain is the subunit of the epithelial-cell-specific laminin...
  60. ncbi request reprint A compilation of partial sequences of randomly selected cDNA clones from the rat incisor
    Y Matsuki
    Laboratory of Developmental Biology, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892
    J Dent Res 74:307-12. 1995
    ..Further characterization of the clones described in this paper should lead to the discovery of novel genes important for tooth development...
  61. pmc Isolation of genomic DNA clones spanning the entire fibronectin gene
    H Hirano
    Proc Natl Acad Sci U S A 80:46-50. 1983
    ..These results suggest that the gene for fibronectin may have arisen by multiple gene duplications of a primordial gene or genes approximately equal to 150 base pairs long...
  62. ncbi request reprint Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3
    S Seino
    Department of Medicine, University of Chicago, Illinois 60637
    Genomics 13:1375-7. 1992