Affiliation: Chugai Pharmaceutical Co
- Identification of deamidation and isomerization sites on pharmaceutical recombinant antibody using H(2)(18)OIsamu Terashima
Analytical Technology Research Department, Chugai Pharmaceutical, Tokyo 115 8543, Japan
Anal Biochem 368:49-60. 2007..By means of this procedure, identification of deamidation and isomerization sites can be accomplished easily even when they are difficult or impossible to detect by the usual peptide mapping...