T Sugihara

Summary

Affiliation: Chugai Research Institute for Molecular Medicine
Country: Japan

Publications

  1. ncbi request reprint A novel testis-specific metallothionein-like protein, tesmin, is an early marker of male germ cell differentiation
    T Sugihara
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, 1 1 Higashi, Tsukuba, 305 8566, Japan
    Genomics 57:130-6. 1999
  2. ncbi request reprint Gros1, a potential growth suppressor on chromosome 1: its identity to basement membrane-associated proteoglycan, leprecan
    S C Kaul
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
    Oncogene 19:3576-83. 2000
  3. ncbi request reprint A novel alternatively spliced form of murine vascular endothelial growth factor, VEGF 115
    T Sugihara
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, 1 1 Higashi, Tsukuba, Ibaraki 305, Japan
    J Biol Chem 273:3033-8. 1998
  4. ncbi request reprint The ARF-p53 senescence pathway in mouse and human cells
    R Wadhwa
    National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    Histol Histopathol 19:311-6. 2004
  5. ncbi request reprint Genetic differences between the pancytosolic and perinuclear forms of murine mortalin
    R Wadhwa
    Children s Medical Research Institute, Sydney, New South Wales, Australia
    Exp Cell Res 226:381-6. 1996
  6. ncbi request reprint Cloning and characterization of a novel gene, striamin, that interacts with the tumor suppressor protein p53
    R Wadhwa
    Chugai Research Institute for Molecular Medicine, 153 2 Nagai, Niihari Mura, Niihari Gun, Ibaraki 300 41, Japan
    J Biol Chem 274:14948-55. 1999
  7. ncbi request reprint Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway
    T Sugihara
    Chugai Research Institute for Molecular Medicine, 153 2 Nagai, Niihari Mura, Ibaraki 300 41, Japan
    J Biol Chem 276:18649-52. 2001
  8. ncbi request reprint Cell cycle analysis and expression of cell cycle regulator genes in myeloma cells overexpressing cyclin D1
    K Yata
    Division of Haematology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Br J Haematol 114:591-9. 2001
  9. ncbi request reprint Homozygous missense mutation (band 3 Fukuoka: G130R): a mild form of hereditary spherocytosis with near-normal band 3 content and minimal changes of membrane ultrastructure despite moderate protein 4.2 deficiency
    T Inoue
    Department of Medicine, Kawasaki Medical School, Kurashiki City, Japan
    Br J Haematol 102:932-9. 1998
  10. ncbi request reprint Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells
    T Otsuki
    Department of Hygiene, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Br J Haematol 127:292-8. 2004

Collaborators

Detail Information

Publications10

  1. ncbi request reprint A novel testis-specific metallothionein-like protein, tesmin, is an early marker of male germ cell differentiation
    T Sugihara
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, 1 1 Higashi, Tsukuba, 305 8566, Japan
    Genomics 57:130-6. 1999
    ..Furthermore, adult W/Wv sterile mice that harbor the c-kit mutation lacked tesmin expression. The gene is assigned to mouse chromosome 19B, which has been reported to translocate (11;19) in male sterile mice...
  2. ncbi request reprint Gros1, a potential growth suppressor on chromosome 1: its identity to basement membrane-associated proteoglycan, leprecan
    S C Kaul
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
    Oncogene 19:3576-83. 2000
    ..We describe here cloning, expression and biological activity analysis implying that this novel proteoglycan is a potential growth suppressor on chromosome 1p31, frequently altered in many malignancies...
  3. ncbi request reprint A novel alternatively spliced form of murine vascular endothelial growth factor, VEGF 115
    T Sugihara
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, 1 1 Higashi, Tsukuba, Ibaraki 305, Japan
    J Biol Chem 273:3033-8. 1998
    ..We analyzed these three P1 clones on Southern blots with common and specific probes for VEGF 164 and VEGF 115. The results support the hypothesis that VEGF 115 is a new alternatively spliced form of mouse VEGF...
  4. ncbi request reprint The ARF-p53 senescence pathway in mouse and human cells
    R Wadhwa
    National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    Histol Histopathol 19:311-6. 2004
    ....
  5. ncbi request reprint Genetic differences between the pancytosolic and perinuclear forms of murine mortalin
    R Wadhwa
    Children s Medical Research Institute, Sydney, New South Wales, Australia
    Exp Cell Res 226:381-6. 1996
    ..Furthermore, there appears to be a correlation between frequency of spontaneous immortalization of cultured mouse fibroblasts and the mot loci present in the mouse strain from which they were derived...
  6. ncbi request reprint Cloning and characterization of a novel gene, striamin, that interacts with the tumor suppressor protein p53
    R Wadhwa
    Chugai Research Institute for Molecular Medicine, 153 2 Nagai, Niihari Mura, Niihari Gun, Ibaraki 300 41, Japan
    J Biol Chem 274:14948-55. 1999
    ..Furthermore, it repressed p53 activity in p53-mediated reporter assays. Fluorescence in situ hybridization with a mouse P1 genomic clone localized the gene to chromosome 12C3, which is syntenic to human chromosome 14q21-22...
  7. ncbi request reprint Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway
    T Sugihara
    Chugai Research Institute for Molecular Medicine, 153 2 Nagai, Niihari Mura, Ibaraki 300 41, Japan
    J Biol Chem 276:18649-52. 2001
    ..The data demonstrated a novel mechanism of down-regulation of the p19ARF-p53 pathway...
  8. ncbi request reprint Cell cycle analysis and expression of cell cycle regulator genes in myeloma cells overexpressing cyclin D1
    K Yata
    Division of Haematology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Br J Haematol 114:591-9. 2001
    ....
  9. ncbi request reprint Homozygous missense mutation (band 3 Fukuoka: G130R): a mild form of hereditary spherocytosis with near-normal band 3 content and minimal changes of membrane ultrastructure despite moderate protein 4.2 deficiency
    T Inoue
    Department of Medicine, Kawasaki Medical School, Kurashiki City, Japan
    Br J Haematol 102:932-9. 1998
    ..2 deficiencies...
  10. ncbi request reprint Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells
    T Otsuki
    Department of Hygiene, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Br J Haematol 127:292-8. 2004
    ..5. These results suggested that PGP9.5 may be a good marker for myeloma among haematological malignancies. In addition, it may indicate certain cellular features of myeloma cells, such as sensitivity to proteasome inhibitors...