T Sugihara

Summary

Affiliation: Chugai Research Institute for Molecular Medicine
Country: Japan

Publications

  1. ncbi A novel testis-specific metallothionein-like protein, tesmin, is an early marker of male germ cell differentiation
    T Sugihara
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, 1 1 Higashi, Tsukuba, 305 8566, Japan
    Genomics 57:130-6. 1999
  2. ncbi Gros1, a potential growth suppressor on chromosome 1: its identity to basement membrane-associated proteoglycan, leprecan
    S C Kaul
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
    Oncogene 19:3576-83. 2000
  3. ncbi A novel alternatively spliced form of murine vascular endothelial growth factor, VEGF 115
    T Sugihara
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, 1 1 Higashi, Tsukuba, Ibaraki 305, Japan
    J Biol Chem 273:3033-8. 1998
  4. ncbi The ARF-p53 senescence pathway in mouse and human cells
    R Wadhwa
    National Institute of Advanced Industrial Science and Technology (AIST, Tsukuba, Ibaraki, Japan
    Histol Histopathol 19:311-6. 2004
  5. ncbi Genetic differences between the pancytosolic and perinuclear forms of murine mortalin
    R Wadhwa
    Children s Medical Research Institute, Sydney, New South Wales, Australia
    Exp Cell Res 226:381-6. 1996
  6. ncbi Cloning and characterization of a novel gene, striamin, that interacts with the tumor suppressor protein p53
    R Wadhwa
    Chugai Research Institute for Molecular Medicine, 153 2 Nagai, Niihari Mura, Niihari Gun, Ibaraki 300 41, Japan
    J Biol Chem 274:14948-55. 1999
  7. ncbi Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway
    T Sugihara
    Chugai Research Institute for Molecular Medicine, 153 2 Nagai, Niihari Mura, Ibaraki 300 41, Japan
    J Biol Chem 276:18649-52. 2001
  8. ncbi Cell cycle analysis and expression of cell cycle regulator genes in myeloma cells overexpressing cyclin D1
    K Yata
    Division of Haematology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Br J Haematol 114:591-9. 2001
  9. ncbi Homozygous missense mutation (band 3 Fukuoka: G130R): a mild form of hereditary spherocytosis with near-normal band 3 content and minimal changes of membrane ultrastructure despite moderate protein 4.2 deficiency
    T Inoue
    Department of Medicine, Kawasaki Medical School, Kurashiki City, Japan
    Br J Haematol 102:932-9. 1998
  10. ncbi Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells
    T Otsuki
    Department of Hygiene, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Br J Haematol 127:292-8. 2004

Collaborators

Detail Information

Publications10

  1. ncbi A novel testis-specific metallothionein-like protein, tesmin, is an early marker of male germ cell differentiation
    T Sugihara
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, 1 1 Higashi, Tsukuba, 305 8566, Japan
    Genomics 57:130-6. 1999
    ..Furthermore, adult W/Wv sterile mice that harbor the c-kit mutation lacked tesmin expression. The gene is assigned to mouse chromosome 19B, which has been reported to translocate (11;19) in male sterile mice...
  2. ncbi Gros1, a potential growth suppressor on chromosome 1: its identity to basement membrane-associated proteoglycan, leprecan
    S C Kaul
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
    Oncogene 19:3576-83. 2000
    ..We describe here cloning, expression and biological activity analysis implying that this novel proteoglycan is a potential growth suppressor on chromosome 1p31, frequently altered in many malignancies...
  3. ncbi A novel alternatively spliced form of murine vascular endothelial growth factor, VEGF 115
    T Sugihara
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, 1 1 Higashi, Tsukuba, Ibaraki 305, Japan
    J Biol Chem 273:3033-8. 1998
    ..We analyzed these three P1 clones on Southern blots with common and specific probes for VEGF 164 and VEGF 115. The results support the hypothesis that VEGF 115 is a new alternatively spliced form of mouse VEGF...
  4. ncbi The ARF-p53 senescence pathway in mouse and human cells
    R Wadhwa
    National Institute of Advanced Industrial Science and Technology (AIST, Tsukuba, Ibaraki, Japan
    Histol Histopathol 19:311-6. 2004
    ....
  5. ncbi Genetic differences between the pancytosolic and perinuclear forms of murine mortalin
    R Wadhwa
    Children s Medical Research Institute, Sydney, New South Wales, Australia
    Exp Cell Res 226:381-6. 1996
    ..Furthermore, there appears to be a correlation between frequency of spontaneous immortalization of cultured mouse fibroblasts and the mot loci present in the mouse strain from which they were derived...
  6. ncbi Cloning and characterization of a novel gene, striamin, that interacts with the tumor suppressor protein p53
    R Wadhwa
    Chugai Research Institute for Molecular Medicine, 153 2 Nagai, Niihari Mura, Niihari Gun, Ibaraki 300 41, Japan
    J Biol Chem 274:14948-55. 1999
    ..Furthermore, it repressed p53 activity in p53-mediated reporter assays. Fluorescence in situ hybridization with a mouse P1 genomic clone localized the gene to chromosome 12C3, which is syntenic to human chromosome 14q21-22...
  7. ncbi Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway
    T Sugihara
    Chugai Research Institute for Molecular Medicine, 153 2 Nagai, Niihari Mura, Ibaraki 300 41, Japan
    J Biol Chem 276:18649-52. 2001
    ..The data demonstrated a novel mechanism of down-regulation of the p19ARF-p53 pathway...
  8. ncbi Cell cycle analysis and expression of cell cycle regulator genes in myeloma cells overexpressing cyclin D1
    K Yata
    Division of Haematology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Br J Haematol 114:591-9. 2001
    ....
  9. ncbi Homozygous missense mutation (band 3 Fukuoka: G130R): a mild form of hereditary spherocytosis with near-normal band 3 content and minimal changes of membrane ultrastructure despite moderate protein 4.2 deficiency
    T Inoue
    Department of Medicine, Kawasaki Medical School, Kurashiki City, Japan
    Br J Haematol 102:932-9. 1998
    ..2 deficiencies...
  10. ncbi Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells
    T Otsuki
    Department of Hygiene, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Br J Haematol 127:292-8. 2004
    ..5. These results suggested that PGP9.5 may be a good marker for myeloma among haematological malignancies. In addition, it may indicate certain cellular features of myeloma cells, such as sensitivity to proteasome inhibitors...