Kouki Obata

Summary

Affiliation: Chugai Pharmaceutical Co
Country: Japan

Publications

  1. ncbi request reprint Biopharmaceutics classification by high throughput solubility assay and PAMPA
    Kouki Obata
    Pre clinical Research Department I, Chugai Pharmaceutical Co, Ltd, Gotemba, Shizuoka, Japan
    Drug Dev Ind Pharm 30:181-5. 2004
  2. ncbi request reprint Prediction of oral drug absorption in humans by theoretical passive absorption model
    Kouki Obata
    Pre clinical Research Department I, Chugai Pharmaceutical Co Ltd, 1 135 Komakado, Gotemba, Shizuoka 412 8513, Japan
    Int J Pharm 293:183-92. 2005
  3. doi request reprint High-throughput formulation screening system for self-microemulsifying drug delivery
    Kenichi Sakai
    Formulation Technology Research Department, Chugai Pharmaceutical Co, Ltd, Kita ku, Tokyo, Japan
    Drug Dev Ind Pharm 35:746-55. 2009
  4. doi request reprint Design of self-microemulsifying drug delivery systems using a high-throughput formulation screening system
    Kenichi Sakai
    Production Engineering Department Formulation Technology, Chugai Pharmaceutical Co, Ltd, Tokyo, Japan
    Drug Dev Ind Pharm 36:1245-52. 2010
  5. doi request reprint High drug loading self-microemulsifying/micelle formulation: design by high-throughput formulation screening system and in vivo evaluation
    Kenichi Sakai
    Production Engineering Department Formulation Technology, Chugai Pharmaceutical Co, Ltd, Tokyo, Japan
    Drug Dev Ind Pharm 38:1254-61. 2012

Detail Information

Publications5

  1. ncbi request reprint Biopharmaceutics classification by high throughput solubility assay and PAMPA
    Kouki Obata
    Pre clinical Research Department I, Chugai Pharmaceutical Co, Ltd, Gotemba, Shizuoka, Japan
    Drug Dev Ind Pharm 30:181-5. 2004
    ..Fourteen out of 18 drugs were correctly classified (78% success rate). The result of the present study showed that HTSA could predict BCS class with a high success rate, and PAMPA could also be useful to predict the permeation of drugs...
  2. ncbi request reprint Prediction of oral drug absorption in humans by theoretical passive absorption model
    Kouki Obata
    Pre clinical Research Department I, Chugai Pharmaceutical Co Ltd, 1 135 Komakado, Gotemba, Shizuoka 412 8513, Japan
    Int J Pharm 293:183-92. 2005
    ..67-0.77, as well as the contribution of paracellular permeation. The TPAM was found to predict oral absorption from the chemical structure of drugs with adequate predictability for usage in drug discovery...
  3. doi request reprint High-throughput formulation screening system for self-microemulsifying drug delivery
    Kenichi Sakai
    Formulation Technology Research Department, Chugai Pharmaceutical Co, Ltd, Kita ku, Tokyo, Japan
    Drug Dev Ind Pharm 35:746-55. 2009
    ..To develop a high-throughput formulation screening (HTFS) system for self-microemulsifying drug delivery system (SMEDDS) formulations...
  4. doi request reprint Design of self-microemulsifying drug delivery systems using a high-throughput formulation screening system
    Kenichi Sakai
    Production Engineering Department Formulation Technology, Chugai Pharmaceutical Co, Ltd, Tokyo, Japan
    Drug Dev Ind Pharm 36:1245-52. 2010
    ..The purpose of this study was to investigate the applicability of the HTFS system to SMEDDS designs...
  5. doi request reprint High drug loading self-microemulsifying/micelle formulation: design by high-throughput formulation screening system and in vivo evaluation
    Kenichi Sakai
    Production Engineering Department Formulation Technology, Chugai Pharmaceutical Co, Ltd, Tokyo, Japan
    Drug Dev Ind Pharm 38:1254-61. 2012
    ..To design a high drug loading formulation of self-microemulsifying/micelle system...