Research Topics
| Fumihiko HorioSummaryAffiliation: Chubu University Country: Japan Publications
| Collaborators
|
Detail Information
Publications
The HND mouse, a nonobese model of type 2 diabetes mellitus with impaired insulin secretionFumihiko Horio
Department of Food and Nutritional Sciences, College of Bioscience and Biotechnology, Chubu University, Matsumoto cho 1200, Kasugai 487 8501, Japan
Eur J Endocrinol 153:971-9. 2005....- Ascorbic acid deficiency stimulates hepatic expression of inflammatory chemokine, cytokine-induced neutrophil chemoattractant-1, in scurvy-prone ODS ratsFumihiko Horio
Department of Food and Nutritional Sciences, College of Bioscience and Biotechnology, Chubu University, Aichi, Japan
J Nutr Sci Vitaminol (Tokyo) 52:28-32. 2006..These results demonstrate that ascorbic acid deficiency elevates the serum, liver and spleen concentrations of CINC-1 as seen in acute inflammation, and suggest that ascorbic acid deficiency stimulate the hepatic CINC-1 gene expression... 
Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic miceMasahito Takikawa
College of Bioscience and Biotechnology, Chubu University, Kasugai, Aichi 487 8501, Japan
J Nutr 140:527-33. 2010..These findings provide a biochemical basis for the use of bilberry fruits and have important implications for the prevention and treatment of type 2 diabetes via activation of AMPK...- Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic miceRie Sasaki
College of Bioscience and Biotechnology, Chubu University, Matsumoto cho, Kasugai, Aichi 487 8501, Japan
Biochem Pharmacol 74:1619-27. 2007..These findings indicate that C3G has significant potency in an anti-diabetic effect through the regulation of Glut4-RBP4 system and the related inflammatory adipocytokines... - Calmodulin overexpression causes Ca(2+)-dependent apoptosis of pancreatic beta cells, which can be prevented by inhibition of nitric oxide synthaseWei Yu
Department of Anatomy, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
Lab Invest 82:1229-39. 2002.... - Suppressive effect of a hot water extract of adzuki beans (Vigna angularis) on hyperglycemia after sucrose loading in mice and diabetic ratsTomohiro Itoh
Imuraya Confectionary Co Ltd, Takachaya 7 1 1, Tsu, Mie 514 8530, Japan
Biosci Biotechnol Biochem 68:2421-6. 2004.... - Characterization of diabetes-related traits in MSM and JF1 mice on high-fat dietMisato Kobayashi
Department of Applied Molecular Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan
J Nutr Biochem 15:614-21. 2004..Further investigations using JF1 mice will help to clarify the role of the high-fat diet on human diabetes and obesity... - SMXA-5 mouse as a diabetic model susceptible to feeding a high-fat dietMisato Kobayashi
Department of Applied Molecular Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University
Biosci Biotechnol Biochem 68:226-30. 2004..On the other hand, SM/J showed mildly impaired glucose tolerance, even when fed on a high-fat diet for 10 weeks. These results indicate that SMXA-5 would be available for use as a diabetic model susceptible to a high-fat diet... - Characteristics of ascorbic acid metabolism in scurvy-prone spontaneously hypertensive rat, SHR-odKaori Kawai
Department of Applied Molecular Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan
J Nutr Sci Vitaminol (Tokyo) 49:1-6. 2003.... - Dietary sesame seed and its lignan increase both ascorbic acid concentration in some tissues and urinary excretion by stimulating biosynthesis in ratsSaiko Ikeda
Department of Nutritional Sciences, Nagoya University of Arts and Sciences, Nissin, Japan
J Nutr Sci Vitaminol (Tokyo) 53:383-92. 2007..The data of ODS rat studies also suggest that dietary sesame seed enhances antioxidative activity in the tissues by elevating the levels of two antioxidative vitamins, vitamin C and E... - Changes in catecholamine metabolism by ascorbic acid deficiency in spontaneously hypertensive rats unable to synthesize ascorbic acidKaori Kawai
Department of Applied Molecular Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan
Life Sci 72:1717-32. 2003.... - Dietary cyanidin 3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in miceTakanori Tsuda
Research Center for Biomarkers of Preventive Medicine, Doshisha University, Imadegawa dori, Kamigyo ku, Kyoto 602 8580, Japan
J Nutr 133:2125-30. 2003..Our findings provide a biochemical and nutritional basis for the use of PCC or anthocyanins as a functional food factor that may have benefits for the prevention of obesity and diabetes... - Quantitative trait loci for impaired glucose tolerance in nondiabetic SM/J and A/J miceNatsuko Hada
Department of Applied Molecular Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
Physiol Genomics 35:65-74. 2008..A-T2dm2sa mice... - Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat dietMayumi Kumazawa
Department of Applied Molecular Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
J Lipid Res 48:2039-46. 2007..This suggests that the SM/J and A/J strains, neither of which develops fatty liver, possess loci causing fatty liver and that the coexistence of these loci causes fatty liver in SMXA-5 mice... - Anthocyanin enhances adipocytokine secretion and adipocyte-specific gene expression in isolated rat adipocytesTakanori Tsuda
Research Center for Biomarkers of Preventive Medicine, Doshisha University, Kamigyo ku, Kyoto 602 8580, Japan
Biochem Biophys Res Commun 316:149-57. 2004..These data suggest that anthocyanins have a potency of unique therapeutic advantage and also have important implications for preventing obesity and diabetes... - Quantitative trait locus analysis of serum insulin, triglyceride, total cholesterol and phospholipid levels in the (SM/J x A/J)F2 miceRea Victoria P Anunciado
Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University, Furocho, Chikusa ku, Nagoya 464 8601, Japan
Exp Anim 52:37-42. 2003..The QTL on Chr 8 affected insulin and phospholipid levels, whereas the Chr 19 QTL was common to the three lipid parameters... - Cyanidin 3-O-beta-D-glucoside suppresses nitric oxide production during a zymosan treatment in ratsTakanori Tsuda
Junior College Division, Tokai Gakuen University, 2-901 Nakahira, Tenpaku-ku, Nagoya 468-8514, Japan
J Nutr Sci Vitaminol (Tokyo) 48:305-10. 2002..Taken altogether, our findings provide a biochemical basis for the use of C3G as a functional food factor and can also have important implications for the prevention of the NO-mediated inflammatory diseases... - Cyanidin 3-O-beta-D-glucoside attenuates the hepatic ischemia-reperfusion injury through a decrease in the neutrophil chemoattractant production in ratsTakanori Tsuda
Junior College Division, Tokai Gakuen University, Nagoya, Japan
J Nutr Sci Vitaminol (Tokyo) 48:134-41. 2002.... - Increase in oxidative stress in kidneys of diabetic Akita miceYuki Ueno
Nagoya University Graduate School of Bioagricultural Sciences, Japan
Biosci Biotechnol Biochem 66:869-72. 2002..These results suggest that hyperglycemia in Akita mice induced oxidative stress and increased these markers in the kidneys... - Effects of paraquat on essential antioxidant elements in osteogenic disorder Shionogi ratKayoko Minakata
Department of Legal Medicine, Hamamatsu University School of Medicine, Japan
J Toxicol Environ Health A 65:143-7. 2002..PQ produced an increase in kidney Mg and a rise in liver Mg and Zn levels. Cardiac elemental levels were not affected by PQ treatment. PQ, a known oxidant, produced changes in tissue elements involved in antioxidant mechanisms...