Shiroh Isono

Summary

Affiliation: Chiba University
Country: Japan

Publications

  1. ncbi Anatomy of pharynx in patients with obstructive sleep apnea and in normal subjects
    S Isono
    Department of Anesthesiology, Chiba University School of Medicine, Chuo Ku, Japan
    J Appl Physiol (1985) 82:1319-26. 1997
  2. ncbi Efficacy of endoscopic static pressure/area assessment of the passive pharynx in predicting uvulopalatopharyngoplasty outcomes
    S Isono
    Department of Anesthesiology, Chiba University School of Medicine, Japan
    Laryngoscope 109:769-74. 1999
  3. ncbi Collapsibility of passive pharynx in patients with acromegaly
    S Isono
    Departments of Anesthesiology and Neurosurgery, Chiba University School of Medicine, Chiba, Japan
    Am J Respir Crit Care Med 160:64-8. 1999
  4. ncbi Developmental changes in collapsibility of the passive pharynx during infancy
    S Isono
    Department of Anesthesiology, Chiba University School of Medicine, Chiba, Japan
    Am J Respir Crit Care Med 162:832-6. 2000
  5. pmc Pathogenesis of laryngeal narrowing in patients with multiple system atrophy
    S Isono
    Department of Anaesthesiology, Chiba University School of Medicine, 1 8 1 Inohana cho, Chuo Ku, Chiba, 260 8670, Japan
    J Physiol 536:237-49. 2001
  6. ncbi Effects of uvulopalatopharyngoplasty on collapsibility of the retropalatal airway in patients with obstructive sleep apnea
    Shiroh Isono
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, 1 8 1 Inohana cho, Chuo Ku, Chiba, 260 8670, Japan
    Laryngoscope 113:362-7. 2003
  7. ncbi Influences of head positions and bite opening on collapsibility of the passive pharynx
    Shiroh Isono
    Department of Anesthesiology B1 Graduate School of Medicine, Chiba University, Chuo Ku, Chiba, 260 8670, Japan
    J Appl Physiol (1985) 97:339-46. 2004
  8. doi Sitting posture decreases collapsibility of the passive pharynx in anesthetized paralyzed patients with obstructive sleep apnea
    Yugo Tagaito
    Department of Anesthesiology, Teikyo University Chiba Medical Center, Ichihara, Japan
    Anesthesiology 113:812-8. 2010
  9. ncbi Sniffing position improves pharyngeal airway patency in anesthetized patients with obstructive sleep apnea
    Shiroh Isono
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, Chiba, Japan
    Anesthesiology 103:489-94. 2005
  10. ncbi Laryngeal reflex before and after placement of airway interventions: endotracheal tube and laryngeal mask airway
    Atsuko Tanaka
    Department of Anesthesiology, Graduate School of Medicine Chiba University, Chiba, Japan
    Anesthesiology 102:20-5. 2005

Collaborators

Detail Information

Publications43

  1. ncbi Anatomy of pharynx in patients with obstructive sleep apnea and in normal subjects
    S Isono
    Department of Anesthesiology, Chiba University School of Medicine, Chuo Ku, Japan
    J Appl Physiol (1985) 82:1319-26. 1997
    ..We conclude that the passive pharynx is more narrow and collapsible in sleep-apneic patients than in matched controls and that velopharyngeal Pc is the principal correlate of the frequency of nocturnal desaturations...
  2. ncbi Efficacy of endoscopic static pressure/area assessment of the passive pharynx in predicting uvulopalatopharyngoplasty outcomes
    S Isono
    Department of Anesthesiology, Chiba University School of Medicine, Japan
    Laryngoscope 109:769-74. 1999
    ..Since UPPP corrects only retropalatal airway (RP) patency, we hypothesized that response to UPPP is determined by collapsibility of the retroglossal airway (RG), where UPPP does not correct...
  3. ncbi Collapsibility of passive pharynx in patients with acromegaly
    S Isono
    Departments of Anesthesiology and Neurosurgery, Chiba University School of Medicine, Chiba, Japan
    Am J Respir Crit Care Med 160:64-8. 1999
    ..Our results suggest that anatomic abnormality, especially at the base of the tongue, appears to play a significant role in development of SDB in acromegaly...
  4. ncbi Developmental changes in collapsibility of the passive pharynx during infancy
    S Isono
    Department of Anesthesiology, Chiba University School of Medicine, Chiba, Japan
    Am J Respir Crit Care Med 162:832-6. 2000
    ..Accordingly, we conclude that anatomic properties of the pharynx gain stability in favor of maintaining patent airway during development in normal infants...
  5. pmc Pathogenesis of laryngeal narrowing in patients with multiple system atrophy
    S Isono
    Department of Anaesthesiology, Chiba University School of Medicine, 1 8 1 Inohana cho, Chuo Ku, Chiba, 260 8670, Japan
    J Physiol 536:237-49. 2001
    ..4. The results indicate that contraction of laryngeal adductors during inspiration narrows the larynx leading to development of inspiratory flow limitation accompanied by stridor in patients with MSA under general anaesthesia...
  6. ncbi Effects of uvulopalatopharyngoplasty on collapsibility of the retropalatal airway in patients with obstructive sleep apnea
    Shiroh Isono
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, 1 8 1 Inohana cho, Chuo Ku, Chiba, 260 8670, Japan
    Laryngoscope 113:362-7. 2003
    ..The present study examined the direct and long-term effects of uvulopalatopharyngoplasty on retropalatal airway collapsibility...
  7. ncbi Influences of head positions and bite opening on collapsibility of the passive pharynx
    Shiroh Isono
    Department of Anesthesiology B1 Graduate School of Medicine, Chiba University, Chuo Ku, Chiba, 260 8670, Japan
    J Appl Physiol (1985) 97:339-46. 2004
    ..Our results indicate the importance of neck and mandibular position for determining patency and collapsibility of the passive pharynx...
  8. doi Sitting posture decreases collapsibility of the passive pharynx in anesthetized paralyzed patients with obstructive sleep apnea
    Yugo Tagaito
    Department of Anesthesiology, Teikyo University Chiba Medical Center, Ichihara, Japan
    Anesthesiology 113:812-8. 2010
    ..The authors tested the hypothesis that the passive pharynx is structurally less collapsible during sitting than during supine posture...
  9. ncbi Sniffing position improves pharyngeal airway patency in anesthetized patients with obstructive sleep apnea
    Shiroh Isono
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, Chiba, Japan
    Anesthesiology 103:489-94. 2005
    ..Although the sniffing neck position is a traditionally recommended head and neck position during this critical period, knowledge of the influences of this position on the pharyngeal airway patency is still inadequate...
  10. ncbi Laryngeal reflex before and after placement of airway interventions: endotracheal tube and laryngeal mask airway
    Atsuko Tanaka
    Department of Anesthesiology, Graduate School of Medicine Chiba University, Chiba, Japan
    Anesthesiology 102:20-5. 2005
    ..The hypothesis was tested by comparing types of experimentally induced laryngeal airway reflexes before and after surgery in anesthetized patients with use of either an ETT or a Laryngeal Mask Airway...
  11. ncbi Dynamic interaction between the tongue and soft palate during obstructive apnea in anesthetized patients with sleep-disordered breathing
    Shiroh Isono
    Department of Anesthesiology B1 Graduate School of Medicine, Chiba University, Chiba 260 8670, Japan
    J Appl Physiol (1985) 95:2257-64. 2003
    ..The results indicate significant dynamic interaction between the tongue and soft palate during both obstructive apnea and each inspiratory effort, possibly maintaining closure at the retropalatal airway...
  12. doi Comparison of pain and dyspnea perceptual responses in healthy subjects
    Takashi Nishino
    Department of Anesthesiology, Graduate School of Medicine Chiba University, 1 8 1 Inohanacho, Chiba 260 8670, Japan
    Pain 148:426-30. 2010
    ..In conclusion, an individual's pain threshold is correlated to the individual's dyspnea threshold, but the individual's pain tolerance is not consistently correlated to the individual's dyspnea tolerance...
  13. ncbi Inspiratory activation of the vocal cord adductor, part II: Animal study in the cat
    Yasuko Sekita
    Department of Otolaryngology, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chiba 260 8670, Japan
    Laryngoscope 114:376-80. 2004
    ..The authors hypothesized that insufficient opening of the glottis during inspiration generates strong negative pressure in the trachea and that this negative pressure triggers an airway reflex that activates the adductor...
  14. ncbi Laryngeal resistance before and after minor surgery: endotracheal tube versus Laryngeal Mask Airway
    Atsuko Tanaka
    Graduate School of Medicine, Chiba University, Chiba, Japan
    Anesthesiology 99:252-8. 2003
    ....
  15. doi How can we improve mask ventilation in patients with obstructive sleep apnea during anesthesia induction?
    Yumi Sato
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, 1 8 1 Inohana cho, Chuo Ku, Chiba, 260 8670, Japan
    J Anesth 27:152-6. 2013
    ....
  16. ncbi Effects of muscle relaxants on mask ventilation in anesthetized persons with normal upper airway anatomy
    Aya Ikeda
    Department of Anesthesiology, Chiba University Hospital, and Department of Anesthesiology, Graduate School of Medicine, Chiba University, Chiba, Japan
    Anesthesiology 117:487-93. 2012
    ..We tested a hypothesis that muscle relaxants, either rocuronium or succinylcholine, improve mask ventilation...
  17. ncbi An additive interaction between different qualities of dyspnea produced in normal human subjects
    Takashi Nishino
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, Chiba, Japan
    Respir Physiol Neurobiol 155:14-21. 2007
    ..These results suggest that despite the difference in quality of sensations, the intensity of dyspnea would sum linearly when the two kinds of loads are presented at the same time...
  18. ncbi Tracheostomy abolishes paradoxical activation of the vocal cord adductor in multiple system atrophy
    Keisuke Shiba
    Department of Otolaryngology, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chiba City, Chiba 260 8670, Japan
    Auris Nasus Larynx 33:295-8. 2006
    ..To confirm the hypothesis that airway reflexes trigger such paradoxical activation, we investigated the effects of tracheostomy on the adductor activation in a MSA patient...
  19. ncbi Dynamic interaction of craniofacial structures during head positioning and direct laryngoscopy in anesthetized patients with and without difficult laryngoscopy
    Yuji Kitamura
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, Chiba, Japan
    Anesthesiology 107:875-83. 2007
    ..We lack fundamental knowledge of the mechanisms of difficult laryngoscopy despite its clinical significance. The aim of this study was to examine how head positioning and direct laryngoscopy alter arrangements of craniofacial structures...
  20. ncbi Prone position increases collapsibility of the passive pharynx in infants and small children
    Teruhiko Ishikawa
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, Chiba, Japan
    Am J Respir Crit Care Med 166:760-4. 2002
    ..We conclude that the prone position increases upper airway collapsibility, although the mechanism is yet unclear...
  21. ncbi Lateral position decreases collapsibility of the passive pharynx in patients with obstructive sleep apnea
    Shiroh Isono
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, Japan
    Anesthesiology 97:780-5. 2002
    ..The authors tested the hypothesis that structural properties of the passive pharynx change by changing the body position from supine to lateral...
  22. pmc Coughing induced by airway irritation modulates the sensation of air hunger
    Takashi Nishino
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, 1 8 1 Inohanacho, Chiba 260 8670, Japan
    J Physiol 586:649-58. 2008
    ..Coughing induced by airway irritation per se does not generate the sensation of air hunger but can aggravate it, presumably by vagally mediated mechanisms and/or central mechanisms...
  23. ncbi Airway protective reflexes evoked by laryngeal instillation of distilled water under sevoflurane general anesthesia in children
    Teruhiko Ishikawa
    Department of Anesthesiology B1, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8677, Japan
    Anesth Analg 101:1615-8. 2005
    ..01). We concluded that, in children, the depth of general anesthesia with sevoflurane modified airway protective reflexes...
  24. ncbi Paradoxical vocal cord motion: a review focused on multiple system atrophy
    Keisuke Shiba
    Department of Otolaryngology, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chiba City, Chiba 260 8670, Japan
    Auris Nasus Larynx 34:443-52. 2007
    ..The following issues are addressed in this review: (1) the pathophysiology of nonorganic and MSA-related PVCM, (2) the relationships between PVCM and airway reflexes, and (3) the treatment for MSA-related PVCM...
  25. ncbi Lung volume and collapsibility of the passive pharynx in patients with sleep-disordered breathing
    Yugo Tagaito
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba Univ Chuo ku, Chiba 260 8670, Japan
    J Appl Physiol 103:1379-85. 2007
    ..We conclude that increase in lung volume structurally improves velopharyngeal collapsibility particularly in obese patients with sleep-disordered breathing...
  26. doi Obstructive sleep apnea of obese adults: pathophysiology and perioperative airway management
    Shiroh Isono
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba, 260 8670, Japan
    Anesthesiology 110:908-21. 2009
    ..Improvement of the pharyngeal anatomical imbalance and maintenance of lung volume are the keys for safe perioperative airway managements of obese patients with obstructive sleep apnea...
  27. doi Lung/chest expansion contributes to generation of pleasantness associated with dyspnoea relief
    Takashi Nishino
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, 1 8 1 Inohanacho, Chiba, Japan
    Respir Physiol Neurobiol 184:27-34. 2012
    ..These findings indicate that an increase in V(T) after removal of respiratory loading plays a crucial role in generation of 'respiratory pleasure' that is a specific sensory-emotional experience...
  28. doi Obesity and obstructive sleep apnoea: mechanisms for increased collapsibility of the passive pharyngeal airway
    Shiroh Isono
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, Chiba, Japan
    Respirology 17:32-42. 2012
    ..Neurostructural interactions required for stable breathing may be influenced by obesity-related hormones and cytokines. Accumulating evidence strongly supports these speculations, but further intensive research is needed...
  29. doi Effects of different forms of dyspnoea on pain perception induced by cold-pressor test
    Eiko Yashiro
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, Chuo Ku, Chiba, Japan
    Respir Physiol Neurobiol 177:320-6. 2011
    ..Our findings suggest that AIR HUNGER and WORK/EFFORT exert a similar analgesic effect although the WORK/EFFORT-induced analgesia was slightly more effective...
  30. ncbi Inspiratory activation of the vocal cord adductor, part I: human study in patients with restricted abduction of the vocal cords
    Keisuke Shiba
    Department of Otolaryngology, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chiba 260 8670, Japan
    Laryngoscope 114:372-5. 2004
    ..However, active glottis narrowing can also be contributory. We tested the hypothesis that the vocal cord adductor is activated during inspiration in patients with restricted abduction of the vocal cords...
  31. ncbi Mandibular advancement improves the laryngeal view during direct laryngoscopy performed by inexperienced physicians
    Miki Tamura
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, Chiba, Japan
    Anesthesiology 100:598-601. 2004
    ..The authors hypothesized that mandibular advancement may also improve the laryngeal view during direct laryngoscopy...
  32. ncbi Quantitative assessment of tracheal collapsibility in infants with tracheomalacia
    Junko Okazaki
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, 1 8 1 Inohana cho, Chuo Ku, Chiba 260 8670, Japan
    Am J Respir Crit Care Med 170:780-5. 2004
    ..It is our conclusion that tracheal collapsibility of infants with tracheomalacia can be quantitatively assessed by the static pressure/area relationship of the trachea obtained under general anesthesia and paralysis...
  33. doi Sex differences in the effect of dyspnea on thermal pain threshold in young healthy subjects
    Takashi Nishino
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, 1 8 1 Inohanacho, Chuo Ku, Chiba 260 8670, Japan
    Anesthesiology 109:1100-6. 2008
    ....
  34. ncbi Contribution of body habitus and craniofacial characteristics to segmental closing pressures of the passive pharynx in patients with sleep-disordered breathing
    Toshihide Watanabe
    Department of Oral Surgery and Anesthesiology, Chiba University School of Medicine, Chiba, Japan
    Am J Respir Crit Care Med 165:260-5. 2002
    ..Furthermore, the relative contribution of obesity and craniofacial anomaly appears to determine the type of pharyngeal closure in SDB...
  35. ncbi Submandible angle in nonobese patients with difficult tracheal intubation
    Noriko Suzuki
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, Chiba, Japan
    Anesthesiology 106:916-23. 2007
    ..The aim of this study was to identify the specific craniofacial features associated with DTI...
  36. ncbi Effects of naloxone on respiratory sensation before and after a removal of severe respiratory stress
    Takashi Nishino
    Department of Anesthesiology, Graduate School of Medicine, Chiba University, Chuo Ku, Chiba, 260 8670 Japan
    Jpn J Physiol 55:117-26. 2005
    ..These findings suggest a small role of opioids in relieving dyspnea and in generating euphoria before and after a sudden removal of stress...
  37. ncbi Ventilatory load compensation response to long-term chest compression in rat model
    Nao Iiyori
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, Chiba, Japan
    Respir Physiol Neurobiol 136:55-63. 2003
    ..These observations suggest that the ventilatory response to chest compression may involve not only neural reflex mechanisms but also other non-reflex mechanisms. Sustained chest compression possibly impairs growth and metabolism...
  38. ncbi Developmental changes of pharyngeal airway patency: implications for pediatric anesthesia
    Shiroh Isono
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, Inohana cho, Chuo Ku, Chiba, Japan
    Paediatr Anaesth 16:109-22. 2006
  39. doi Occipitocervical fusion has potential to improve sleep apnea in patients with rheumatoid arthritis and upper cervical lesions
    Hiromi Ataka
    Department of Orthopaedic Surgery, Matsudo City Hospital, Department of Anesthesiology, Chiba University Graduate School of Medicine, Chiba, Japan
    Spine (Phila Pa 1976) 35:E971-5. 2010
    ..Case series...
  40. ncbi [Potential roles of preoperative upper airway radiographs in planning of perioperative airway management]
    Shiroh Isono
    Department of Anesthesiology B1, Graduate School of Medicine, Chiba University, Chiba 260 8670
    Masui 55:1348-59. 2006
    ..Among the parameters measured by the radiographs, I recommend anesthesiologists to measure distance between the hyoid bone and mandibular plane, which possibly reflects anatomical balance of the upper airway maintenance...
  41. doi Anatomical balance of the upper airway and obstructive sleep apnea
    Satoru Tsuiki
    Japan Somnology Center, Neuropsychiatric Research Institute, Tokyo, Japan
    Anesthesiology 108:1009-15. 2008
    ..The authors hypothesized that anatomical imbalance between the upper airway soft-tissue volume and the craniofacial size (rather than each alone) may result in pharyngeal airway obstruction during sleep, and therefore development of OSA...
  42. ncbi Neoadjuvant chemotherapy prior to radical operation as a risk factor for nocturnal oxygen desaturation in perioperative periods
    Teruhiko Ishikawa
    Division of Operation Theater, Chiba University Hospital, Chiba 260 8677
    Masui 51:408-10. 2002
  43. ncbi One hand, two hands, or no hands for maximizing airway maneuvers?
    Shiroh Isono
    Anesthesiology 109:576-7. 2008