Shigeki Hirano

Summary

Affiliation: Chiba University
Country: Japan

Publications

  1. doi request reprint Functional brain imaging of cognitive dysfunction in Parkinson's disease
    Shigeki Hirano
    Department of Neurology, Chiba University School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba shi, Chiba 260 8670, Japan
    J Neurol Neurosurg Psychiatry 83:963-9. 2012
  2. doi request reprint PET study of brain acetylcholinesterase in cerebellar degenerative disorders
    Shigeki Hirano
    Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan
    Mov Disord 23:1154-60. 2008
  3. doi request reprint Cholinergic imaging in corticobasal syndrome, progressive supranuclear palsy and frontotemporal dementia
    Shigeki Hirano
    Molecular Neuroimaging Group, Molecular Imaging Centre, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba shi, Chiba, 263 8555, Japan
    Brain 133:2058-68. 2010
  4. doi request reprint Ambiguous effects of anti-VEGF monoclonal antibody (bevacizumab) for POEMS syndrome
    Yukari Sekiguchi
    Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan
    J Neurol Neurosurg Psychiatry 84:1346-8. 2013
  5. ncbi request reprint Estimation of plasma IC50 of donepezil hydrochloride for brain acetylcholinesterase inhibition in monkey using N-[11C]methylpiperidin-4-yl acetate ([11C]MP4A) and PET
    Tetsuya Shiraishi
    Department of Medical Imaging, National Institute of Radiological Sciences, Graduate School of Medicine, Chiba University, 4 9 1 Anagawa, Inage Ku, Chiba shi, Chiba 263 8555, Japan
    Neuropsychopharmacology 30:2154-61. 2005
  6. ncbi request reprint [Network analyses in neuroimaging studies]
    Shigeki Hirano
    Department of Neurology, Graduate School of Medicine, Chiba Univeisity, Japan
    Brain Nerve 65:659-67. 2013
  7. ncbi request reprint [Neuroimaging studies of diabetes and risk of Alzheimer's disease]
    Shigeki Hirano
    Department of Neurology, Graduate School of Medicine, Chiba University, Chuo Ku, China
    Brain Nerve 64:1411-9. 2012
  8. doi request reprint Patterns of sensory nerve conduction abnormalities in Fisher syndrome: more predominant involvement of group Ia afferents than skin afferents
    Yukari Sekiguchi
    Department of Neurology, Graduate School of Medicine, Chiba University, 1 8 1, Inohana, Chuo Ku, Chiba 260 8670, Japan
    Clin Neurophysiol 124:1465-9. 2013

Collaborators

Detail Information

Publications8

  1. doi request reprint Functional brain imaging of cognitive dysfunction in Parkinson's disease
    Shigeki Hirano
    Department of Neurology, Chiba University School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba shi, Chiba 260 8670, Japan
    J Neurol Neurosurg Psychiatry 83:963-9. 2012
    ....
  2. doi request reprint PET study of brain acetylcholinesterase in cerebellar degenerative disorders
    Shigeki Hirano
    Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan
    Mov Disord 23:1154-60. 2008
    ..Reduction of AChE activities in the thalamus and cerebellum in MSA and in the thalamus in SCA-3 suggest that cholinergic modulating drugs may have a role in the treatment of ataxia and other symptoms in these disorders...
  3. doi request reprint Cholinergic imaging in corticobasal syndrome, progressive supranuclear palsy and frontotemporal dementia
    Shigeki Hirano
    Molecular Neuroimaging Group, Molecular Imaging Centre, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba shi, Chiba, 263 8555, Japan
    Brain 133:2058-68. 2010
    ..Significant brain cholinergic deficits were not seen in frontotemporal dementia, which may explain the unresponsiveness of this condition to cholinergic modulation therapy...
  4. doi request reprint Ambiguous effects of anti-VEGF monoclonal antibody (bevacizumab) for POEMS syndrome
    Yukari Sekiguchi
    Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan
    J Neurol Neurosurg Psychiatry 84:1346-8. 2013
    ..Anti-VEGF antibody (bevacizumab) appears to be an attractive therapeutic option. The aim of this study is to investigate the effects of bevacizumab for patients with POEMS syndrome...
  5. ncbi request reprint Estimation of plasma IC50 of donepezil hydrochloride for brain acetylcholinesterase inhibition in monkey using N-[11C]methylpiperidin-4-yl acetate ([11C]MP4A) and PET
    Tetsuya Shiraishi
    Department of Medical Imaging, National Institute of Radiological Sciences, Graduate School of Medicine, Chiba University, 4 9 1 Anagawa, Inage Ku, Chiba shi, Chiba 263 8555, Japan
    Neuropsychopharmacology 30:2154-61. 2005
    ..The IC(50) values (estimate+/-SE) were 42+/-9.0 (ng/ml; donepezil-1), 34+/-3.2 (donepezil-2), and 37+/-4.1 (combined data). The present method may be useful for in vivo evaluation of other AChE inhibitors and novel drugs...
  6. ncbi request reprint [Network analyses in neuroimaging studies]
    Shigeki Hirano
    Department of Neurology, Graduate School of Medicine, Chiba Univeisity, Japan
    Brain Nerve 65:659-67. 2013
    ..Future neuroimaging network analysis studies will reveal novel and interesting findings that will uncover the pathomechanisms of neurological and psychiatric disorders...
  7. ncbi request reprint [Neuroimaging studies of diabetes and risk of Alzheimer's disease]
    Shigeki Hirano
    Department of Neurology, Graduate School of Medicine, Chiba University, Chuo Ku, China
    Brain Nerve 64:1411-9. 2012
    ..Studies on the brain of patients with diabetes may provide clues for preventive therapy in AD...
  8. doi request reprint Patterns of sensory nerve conduction abnormalities in Fisher syndrome: more predominant involvement of group Ia afferents than skin afferents
    Yukari Sekiguchi
    Department of Neurology, Graduate School of Medicine, Chiba University, 1 8 1, Inohana, Chuo Ku, Chiba 260 8670, Japan
    Clin Neurophysiol 124:1465-9. 2013
    ..To elucidate the features of sensory nerve involvement in Fisher syndrome (FS), this study extensively investigated sensory electrophysiology...