Katsunori Fujii

Summary

Affiliation: Chiba University
Country: Japan

Publications

  1. ncbi request reprint High-density oligonucleotide array with sub-kilobase resolution reveals breakpoint information of submicroscopic deletions in nevoid basal cell carcinoma syndrome
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, 260 8670, Japan
    Hum Genet 122:459-66. 2007
  2. doi request reprint 14-3-3 proteins, particularly of the epsilon isoform, are detectable in cerebrospinal fluids of cerebellar diseases in children
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Brain Dev 35:555-60. 2013
  3. doi request reprint Acute disseminated encephalomyelitis following 2009 H1N1 influenza vaccine
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Pediatr Int 54:539-41. 2012
  4. doi request reprint Multiple cavitations in posterior reversible leukoencephalopathy syndrome associated with hemolytic-uremic syndrome
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chuo Ku, Chiba, Japan
    Brain Dev 34:318-21. 2012
  5. ncbi request reprint Acute motor axonal neuropathy during intensive immunosuppressive therapy for macrophage activation syndrome
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Brain Dev 30:160-3. 2008
  6. ncbi request reprint 14-3-3 protein detection in the cerebrospinal fluid of patients with influenza-associated encephalopathy
    Katsunori Fujii
    Department of Pediatrics, Graduate School of Medicine, Chiba University, and the Division of Neurology, Chiba Children s Hospital, Japan
    J Child Neurol 21:562-5. 2006
  7. doi request reprint Homozygous female Becker muscular dystrophy
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Am J Med Genet A 149:1052-5. 2009
  8. ncbi request reprint Detection of 14-3-3 protein in the cerebrospinal fluid in mitochondrial encephalopathy with lactic acidosis and stroke-like episodes
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chiba shi, Chiba 260 8670, Japan
    J Neurol Sci 239:115-8. 2005
  9. ncbi request reprint [Hedgehog signaling pathway and human disorders]
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba
    No To Hattatsu 41:247-52. 2009
  10. ncbi request reprint Gorlin syndrome with ulcerative colitis in a Japanese girl
    Katsunori Fujii
    Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan
    Am J Med Genet A 121:65-8. 2003

Collaborators

Detail Information

Publications38

  1. ncbi request reprint High-density oligonucleotide array with sub-kilobase resolution reveals breakpoint information of submicroscopic deletions in nevoid basal cell carcinoma syndrome
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, 260 8670, Japan
    Hum Genet 122:459-66. 2007
    ..This method will contribute to the understanding of molecular pathogenesis of gene deletions as well as rapid genetic testing...
  2. doi request reprint 14-3-3 proteins, particularly of the epsilon isoform, are detectable in cerebrospinal fluids of cerebellar diseases in children
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Brain Dev 35:555-60. 2013
    ..There have been useful studies on 14-3-3 CSF protein detection in Creutzfeldt-Jakob disease and other neurological disorders, but none on cerebellar diseases...
  3. doi request reprint Acute disseminated encephalomyelitis following 2009 H1N1 influenza vaccine
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Pediatr Int 54:539-41. 2012
    ..Although vaccine-associated ADEM remains rare, the increasing number of influenza vaccinations might increase the incidence of ADEM. We still need to pay attention to the occurrence of ADEM and treat patients with steroid therapy...
  4. doi request reprint Multiple cavitations in posterior reversible leukoencephalopathy syndrome associated with hemolytic-uremic syndrome
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chuo Ku, Chiba, Japan
    Brain Dev 34:318-21. 2012
    ..We concluded that precipitating factors, i.e., clotting abnormalities, Shiga toxin, vasospasms and endothelial dysfunction might have synergistically induced irreversible brain infarcts, and caused unusual cavitations...
  5. ncbi request reprint Acute motor axonal neuropathy during intensive immunosuppressive therapy for macrophage activation syndrome
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Brain Dev 30:160-3. 2008
    ....
  6. ncbi request reprint 14-3-3 protein detection in the cerebrospinal fluid of patients with influenza-associated encephalopathy
    Katsunori Fujii
    Department of Pediatrics, Graduate School of Medicine, Chiba University, and the Division of Neurology, Chiba Children s Hospital, Japan
    J Child Neurol 21:562-5. 2006
    ..We conclude that 14-3-3 proteins in cerebrospinal fluid are highly detectable in influenza-associated encephalopathy and thus can be used as a rapid diagnostic marker...
  7. doi request reprint Homozygous female Becker muscular dystrophy
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Am J Med Genet A 149:1052-5. 2009
    ..Our results indicate that dystrophinopathy can also be caused in females by homozygosity, albeit rare...
  8. ncbi request reprint Detection of 14-3-3 protein in the cerebrospinal fluid in mitochondrial encephalopathy with lactic acidosis and stroke-like episodes
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chiba shi, Chiba 260 8670, Japan
    J Neurol Sci 239:115-8. 2005
    ..We conclude that 14-3-3 CSF protein is a useful biological marker of brain disruption in MELAS as well as other neurological disorders...
  9. ncbi request reprint [Hedgehog signaling pathway and human disorders]
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba
    No To Hattatsu 41:247-52. 2009
    ..Thus, understanding of these molecular relationships may facilitate the development of new therapies and treatments for diseases caused by hedgehog signaling disorders...
  10. ncbi request reprint Gorlin syndrome with ulcerative colitis in a Japanese girl
    Katsunori Fujii
    Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan
    Am J Med Genet A 121:65-8. 2003
    ..Since Gorlin syndrome and ulcerative colitis are rare disorders in childhood, this association is interesting, suggesting a correlation between the hedgehog signaling and intestinal disorders...
  11. ncbi request reprint [PTCH1 gene analysis in 25 Japanese patients with Gorlin syndrome]
    Mamiko Endo
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba
    No To Hattatsu 41:259-63. 2009
    ..Our detection rate of PTCH1 mutations, i.e., 86%, was much higher than those previously reported from other countries. The differences may be derived either from ethnicity or the detection methods...
  12. doi request reprint Downregulation of microRNA-431 by human interferon-β inhibits viability of medulloblastoma and glioblastoma cells via upregulation of SOCS6
    Takeshi Tanaka
    Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba 260 8670, Japan
    Int J Oncol 44:1685-90. 2014
    ..We propose that, in medulloblastoma and glioblastoma cells, HuIFN-β decreases miR-431 expression and upregulates SOCS6 expression, and consequently inhibit cell proliferation by suppressing the JAK-STAT signaling pathway. ..
  13. ncbi request reprint Electrophysiological subtypes and prognosis of childhood Guillain-Barré syndrome in Japan
    Kasumi Nagasawa
    Department of Pediatrics, Chiba University School of Medicine, Chiba, Japan
    Muscle Nerve 33:766-70. 2006
    ..In Japanese childhood GBS, the proportion of AIDP and AMAN appears to be similar. Recovery is generally favorable in both subtypes, but some of the AMAN children experienced delayed recovery...
  14. ncbi request reprint [Clinical manifestations in 25 Japanese patients with Gorlin syndrome]
    Ryo Tanabe
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba
    No To Hattatsu 41:253-7. 2009
    ..We conclude that clinical manifestations other than major symptoms are quite variable, and racial differences may influence the occurrence of BCCs in Gorlin syndrome patients...
  15. ncbi request reprint Mutations in the human homologue of Drosophila patched in Japanese nevoid basal cell carcinoma syndrome patients
    Katsunori Fujii
    Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan
    Hum Mutat 21:451-2. 2003
    ..The difference in the detection rate of PTCH mutations among NBCCS between previous reports and ours is due to the difference either in ethnicity or in the detection methods...
  16. ncbi request reprint Frameshift mutation in the PTCH2 gene can cause nevoid basal cell carcinoma syndrome
    Katsunori Fujii
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, 260 8670, Japan
    Fam Cancer 12:611-4. 2013
    ....
  17. doi request reprint Nationwide survey of nevoid basal cell carcinoma syndrome in Japan revealing the low frequency of basal cell carcinoma
    Mamiko Endo
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Am J Med Genet A 158:351-7. 2012
    ..Because the age of BCC onset is generally higher in Japanese NBCCS patients, careful skin examination over a prolonged period of time is warranted...
  18. doi request reprint Acute disseminated encephalomyelitis: the time until diagnosis and its subsequent course in children
    Taku Omata
    1Division of Child Neurology, Chiba Children s Hospital, Chiba, Japan
    J Child Neurol 29:28-30. 2014
    ....
  19. doi request reprint Phrenic nerve palsy associated with birth trauma--case reports and a literature review
    Tadashi Shiohama
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Brain Dev 35:363-6. 2013
    ..We conclude that recently developed VATS plication is a safe and effective treatment for infants with phrenic nerve palsy, and should be considered as a surgical treatment at an early period...
  20. doi request reprint Reversible cerebral vasoconstriction syndrome associated with brain parenchymal hemorrhage
    Yuko Kazato
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Brain Dev 34:696-9. 2012
    ..Immediate magnetic resonance angiography is essential to diagnose this syndrome, and a prompt application of calcium channel inhibitors should be considered to resolve constriction of the vessels and to prevent subsequent brain damage...
  21. doi request reprint Sudden onset odontoid fracture caused by cervical instability in hypotonic cerebral palsy
    Tadashi Shiohama
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan Department of Pediatrics, Asahi General Hospital, Chiba, Japan Electronic address
    Brain Dev 35:925-8. 2013
    ....
  22. doi request reprint Artery tortuosity syndrome exhibiting early-onset emphysema with novel compound heterozygous SLC2A10 mutations
    Yoshiko Takahashi
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
    Am J Med Genet A 161:856-9. 2013
    ..This is the first report of ATS associated with early-onset pulmonary emphysema, suggesting that patients with ATS may also require close attention for chronic obstructive pulmonary disease...
  23. ncbi request reprint Reversible white matter lesions during ketogenic diet therapy in glucose transporter 1 deficiency syndrome
    Tadashi Shiohama
    Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan Electronic address
    Pediatr Neurol 49:493-6. 2013
    ..Glucose transporter type 1 deficiency syndrome is caused by brain energy failure resulting from a disturbance in glucose transport...
  24. ncbi request reprint The evolving MR imaging appearance of lissencephaly: a case report
    Jun ichi Takanashi
    Department of Pediatrics, Kameda Medical Center, 929 Higashi Cho, Kamogawa shi, Chiba 296 8602, Japan
    Brain Dev 29:522-4. 2007
    ..The change of the MR imaging findings may have resulted from myelination in the intracortical and subcortical fibers. It is important for clinicians to be aware of the longitudinal changes of the cerebral cortex in lissencephaly...
  25. ncbi request reprint Recurrent meningitis associated with a petrous apex cephalocele
    Toshino Motojima
    Department of Pediatrics, Graduate School of Medicine, Chiba University, Japan
    J Child Neurol 20:168-70. 2005
    ..Petrous apex cephaloceles are usually an asymptomatic incidental finding in adults; however, they should be considered as a possible cause of CSF rhinorrhea, otorrhea, and recurrent meningitis in children...
  26. doi request reprint Inhibition of cell viability by human IFN-β is mediated by microRNA-431
    Takeshi Tanaka
    Department of Environmental Biochemistry, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chiba 260 8670, Japan
    Int J Oncol 40:1470-6. 2012
    ..Based on these results, we propose that, in RSa cells, HuIFN-β-induced miR-431 expression may down-regulate IGF1R and IRS2 expression, and consequently inhibit cell proliferation by suppressing the MAPK pathway...
  27. ncbi request reprint A posterior fossa lipoma extending into the cervical spine and subcutaneous space via a cranium bifidum
    Tomozumi Takatani
    Department of Pediatrics, Chiba Medical Center, Chiba, Japan
    Brain Dev 30:603-5. 2008
    ..Although intracranial lipomas are usually benign and asymptomatic, early detection of them is quite critical, and body weight control may help to prevent their progression...
  28. doi request reprint A splenial lesion with transiently reduced diffusion in clinically mild encephalitis is not always reversible: A case report
    Yuji Hashimoto
    Department of Pediatrics and Radiology, Teikyo University Chiba Medical Center, Chiba, Japan
    Brain Dev 31:710-2. 2009
    ..It is suggested that a splenial lesion with transiently reduced diffusion in clinically mild encephalitis/encephalopathy is not always reversible, and could result in gliosis...
  29. ncbi request reprint IL-10 gene polymorphism, but not TGF-beta1 gene polymorphisms, is associated with food allergy in a Japanese population
    Eduardo Jose Campos Alberto
    Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan
    Pediatr Allergy Immunol 19:716-21. 2008
    ..Our results indicate that IL-10 A-1082G gene polymorphism is associated with food allergy susceptibility in atopic Japanese children...
  30. doi request reprint Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity
    Shinsuke Ohba
    Department of Sensory and Motor System Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Dev Cell 14:689-99. 2008
    ..These data provide evidence that Hh-Ptch1 signaling plays a crucial role in postnatal bone homeostasis and point to Hh-Ptch1 signaling as a potential molecular target for the treatment of osteoporosis...
  31. doi request reprint Kernicterus in preterm infants
    Akihisa Okumura
    Department of Pediatrics, Juntendo University, School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Pediatrics 123:e1052-8. 2009
    ..We sought to clarify the features of kernicterus in preterm infants...
  32. ncbi request reprint Identification of a novel polymorphism involving a CGG repeat in the PTCH gene and a genome-wide screening of CGG-containing genes
    Kazuaki Nagao
    Department of Genetics, National Research Institute for Child Health and Development, 3 35 31 Taishido, Setagaya Ku, Tokyo 154 8567, Japan
    J Hum Genet 49:97-101. 2004
    ..The localization of a CGG/CCG repeat in PTCH is quite unique in that only four other genes have been found in which the repeat is localized up to 4 bp upstream of the first methionine...
  33. ncbi request reprint Brain- and heart-specific Patched-1 containing exon 12b is a dominant negative isoform and is expressed in medulloblastomas
    Hideki Uchikawa
    Department of Genetics, National Research Institute for Child Health and Development, Tokyo 157 8535, Japan
    Biochem Biophys Res Commun 349:277-83. 2006
    ..Interestingly, Patched12b was found to be expressed in some of the medulloblastoma tissues and cell lines, indicating an important role in the pathogenesis of medulloblastoma as well as brain development...
  34. ncbi request reprint Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarrays
    Kazuaki Nagao
    Department of Genetics, National Research Institute for Child Health and Development, Tokyo, Japan
    Hum Mol Genet 14:3379-88. 2005
    ..Taken together, oligonucleotide microarrays containing exon junction probes are demonstrated to be a powerful tool to investigate tissue-specific regulation of AS and aberrant splicing taking place in genetic disorders...
  35. ncbi request reprint Relationship between change in BMI with age and delayed menarche in female athletes
    Katsunori Fujii
    Health Science, General Education, Aichi Institute of Technology, Yakusa cho, Toyota City, Japan
    J Physiol Anthropol Appl Human Sci 22:97-104. 2003
    ..15+/-0.81 years in the control group, so there was a significant difference (P<0.01) between the two groups. It is suggested that the delayed menarche in athletes is influenced by the stress of regular sports training...
  36. ncbi request reprint Identification and characterization of multiple isoforms of a murine and human tumor suppressor, patched, having distinct first exons
    Kazuaki Nagao
    Department of Genetics, National Research Institute for Child Health and Development, 2 10 1 Ohkura, Setagaya Ku, Tokyo 157 8535, Japan
    Genomics 85:462-71. 2005
    ..This study may shed light on the mechanism whereby a single PTCH gene plays a role in both tumor cell growth and embryonic development...
  37. ncbi request reprint Optimum onset period for training based on maximum peak velocity of height by wavelet interpolation method in Japanese high school athletes
    Katsunori Fujii
    Department of Health Science, General Education, Aichi Institute of Technology
    J Physiol Anthropol Appl Human Sci 24:15-22. 2005
    ....
  38. ncbi request reprint New mutation of the PTCH gene in nevoid basal-cell carcinoma syndrome with West syndrome
    Nobutada Tachi
    School of Health Sciences, Sapporo Medical University, Sapporo, Japan
    Pediatr Neurol 37:363-5. 2007
    ..This mutation causes a shift of the reading frame, and creates a stop codon predicting the truncation of the PTCH protein. This mutation was not found in previously described patients with nevoid basal-cell carcinoma syndrome...