Research Topics
Genomes and GenesSpecies | Yukari EgashiraSummaryAffiliation: Chiba University Country: Japan Publications
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Publications
Dietary protein level and dietary interaction affect quinolinic acid concentration in ratsYukari Egashira
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo 271 8510, Japan
Int J Vitam Nutr Res 77:142-8. 2007..8209, p < 0.01). Increased serum QA concentrations are probably due to a decreased ACMSD activity...- Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosisYukari Egashira
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo shi, Chiba 271 8510, Japan
Int J Vitam Nutr Res 76:28-33. 2006..The role of kidney ACMSD activity may be minimal concerning tryptophan-niacin conversion under this experimental condition... - Differential effects of dietary fatty acids on rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity and gene expressionYukari Egashira
Graduate School of Science and Technology, Chiba University, 648 Matsudo, Chiba 271 8510, Japan
Biochim Biophys Acta 1686:118-24. 2004..Moreover, this study provides the information that a high polyunsaturated fatty acid diet affects the production of quinolinic acid in serum by suppressing the ACMSD activity... - Effect of dietary fiber in edible seaweeds on the development of D-galactosamine-induced hepatopathy in ratsNaoko Kawano
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Japan
J Nutr Sci Vitaminol (Tokyo) 53:446-50. 2007..These results suggest that the protective effect of the three kinds of brown seaweeds Laminaria sp., Sargassum fulvellum and Eisenia bicyclis against D-GalN-hepatopathy was caused at least in part by fucoidan... - Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathwayYukari Egashira
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo 271-8510, Japan
Int J Vitam Nutr Res 76:138-46. 2006..However, pyrazinamide does not affect the transcription level of hepatic ACMSD... 
Mechanism of the suppression against D-galactosamine-induced hepatic injury by dietary amino acids in ratsTorai Komano
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudoshi, 271 8510 Chiba, Japan
Amino Acids 37:239-47. 2009..In conclusion, the suppressive effects of amino acids on D-GalN-induced hepatitis were suggested not to be always mediated by the inhibition of Kupffer cells --> TNF-alpha --> apoptosis pathway...- Expression of rat hepatic 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase is affected by a high protein diet and by streptozotocin-induced diabetesAtsushi Tanabe
Graduate School of Science and Technology, Chiba University, 648 Matsudo, Chiba 271 8510, Japan
J Nutr 132:1153-9. 2002..These results indicated that the fluctuation of hepatic ACMSD mRNA expression was followed by that of ACMSD activity... - Suppressive effect of modified arabinoxylan from rice bran (MGN-3) on D-galactosamine-induced IL-18 expression and hepatitis in ratsSurina Zheng
Laboratory of Food and Nutrition, Graduate School of Horticulture, Chiba University, Matsudo, Chiba, Japan
Biosci Biotechnol Biochem 76:942-6. 2012..The results suggest that MGN-3 and LMW could provide significant protection against D-GalN liver injury, and that IL-18 might be involved in their protective influence... - Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic ratsNaho Sasaki
Graduate School of Horticulture, Chiba University, 648 Mastudo, Mastudo shi, Chiba 2718510, Japan
Eur J Nutr 48:145-53. 2009..However, the states of these metabolites in diabetes have not been clarified enough yet... - Effects of various kinds of edible seaweeds in diets on the development of D-galactosamine-induced hepatopathy in ratsNaoko Kawano
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Chiba, Japan
J Nutr Sci Vitaminol (Tokyo) 53:315-23. 2007..on D-GalN-hepatopathy in rats is related to GSH metabolism in the intestine... - Ferulic acid is quickly absorbed from rat stomach as the free form and then conjugated mainly in liverZhaohui Zhao
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
J Nutr 134:3083-8. 2004..For example, oral administration of FA in capsule form or in a form bonded with sugar esters may provide a more appropriate concentration of FA in the circulation, which may improve its proposed efficacy in preventing chronic disease... - Protection by dietary Spirulina platensis against D-galactosamine--and acetaminophen-induced liver injuriesJun Lu
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo, Chiba, Japan
Br J Nutr 103:1573-6. 2010..These results showed that dietary S. platensis could provide a significant protection against d-GalN- and APAP-induced liver injuries, and IL-18 and lipid peroxidation might be involved in the protective influence of S. platensis... - Dietary linoleic acid suppresses gene expression of rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) and increases quinolinic acid in serumYukari Egashira
Laboratory of Food and Nutrition, Department of Bioproduction Science, Chiba University, Matsudo, Chiba 271 8510, Japan
Adv Exp Med Biol 527:671-4. 2003.... - Phenolic antioxidants richly contained in corn bran are slightly bioavailable in ratsZhaohui Zhao
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
J Agric Food Chem 53:5030-5. 2005.... - Digestion and absorption of ferulic acid sugar esters in rat gastrointestinal tractZhaohui Zhao
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
J Agric Food Chem 51:5534-9. 2003..Such microbial degradation may be an important factor affecting the bioavailability of dietary FA... - L-Gln and L-Ser suppress the D-galactosamine-induced IL-18 expression and hepatitisTorai Komano
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
Biochem Biophys Res Commun 372:688-90. 2008..These results suggest that suppressive effects of some dietary amino acids on the GalN-induced hepatitis are mediated by IL-18 reduction... - Down-regulation of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase by polyunsaturated fatty acids in hepatocytes is not mediated by PPARalphaNaho Sasaki
Graduate School of Science and Technology, Chiba University, 648 Mastudo, Mastudo shi, Chiba 271 8510, Japan
Eur J Nutr 47:80-6. 2008.... 
Purification and molecular cloning of rat 2-amino-3-carboxymuconate-6-semialdehyde decarboxylaseAtsushi Tanabe
Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
Biochem J 361:567-75. 2002..The distribution of ACMSD mRNA expression in various tissues was investigated in the rat by RT-PCR. ACMSD was expressed in the liver and kidney, but not in the other principal organs examined...- Suppressive effect of corn bran hemicellulose on liver injury induced by D-galactosamine in ratsAyako Daizo
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Chiba, Japan
Nutrition 21:1044-51. 2005..This study examined the effect of water-soluble corn bran hemicellulose (CBH) on the development of D-galactosamine (GalN) hepatitis in rats to obtain some knowledge about new functions of dietary fiber... - Purification and characterization of a feruloyl esterase from the intestinal bacterium Lactobacillus acidophilusXiaokun Wang
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo, Chiba 271 0082, Japan
Appl Environ Microbiol 70:2367-72. 2004..Moreover, it released two times more FA from FAXX in the presence of added xylanase... - Protective effect of red-stemmed type of Ipomoea aquatica Forsk against CCl4-induced oxidative damage in miceShizuka Hirai
Laboratory of Food and Nutrition, Division of Applied Biological Chemistry, Graduate School of Horticulture, Chiba University, Matsudo, Chiba, Japan
J Nutr Sci Vitaminol (Tokyo) 57:306-10. 2011..Such effective components in the red type would be beneficial phytochemicals for suppressing several diseases related to oxidative stress... - Ferulic acid sugar esters are recovered in rat plasma and urine mainly as the sulfoglucuronide of ferulic acidZhaohui Zhao
Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 0082, Japan
J Nutr 133:1355-61. 2003..Thus, the physiological functions of FA and its sugar esters found in vitro might require reconsideration in vivo... - Protective effect of low molecular fraction of MGN-3, a modified arabinoxylan from rice bran, on acute liver injury by inhibition of NF-κB and JNK/MAPK expressionSurina Zheng
Laboratory of Food and Nutrition, Graduate School of Horticulture, Chiba University, 648 Matsudo, Matsudo shi, Chiba 271 8510, Japan
Int Immunopharmacol 14:764-9. 2012..These results suggest that the suppressive effects of LMW on GalN-induced hepatitis are possibly related to inhibition of NF-κB, JNK phosphorylation and CD14 expression... - Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis"Shin Ichi Fukuoka
Graduate School of Agriculture, Kyoto University, Uji, Kyoto 611 0011, Japan
J Biol Chem 277:35162-7. 2002..This suggests that a pathway does exist by which the levels of quinolinate in the brain are regulated. In this report, we address the molecular basis underlying quinolinate metabolism and the regulation of ACMSD expression... - Identification and expression of alpha cDNA encoding human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD): a key enzyme for the tryptophan-niacine pathway and quinolinate hypothesisShin Ichi Fukuoka
Graduate School of Agriculuture, Kyoto University, Uji, Kyoto 611 0011, Japan
Adv Exp Med Biol 527:443-53. 2003..This suggests that a pathway does exist by which the levels of quinolinate in the brain are regulated. In this report, we address the molecular basis underlying quinolinate metabolism and the regulation of ACMSD expression... - Effects of dietary corn bran hemicellulose and neomycin on hepatic caspase-3 activity and glycoprotein concentration in rats treated with or without D-galactosamineAyako Daizo
Seitoku University, Chiba, Japan
J Nutr Sci Vitaminol (Tokyo) 52:96-104. 2006.... - Roles of nuclear receptors in the up-regulation of hepatic cholesterol 7alpha-hydroxylase by cholestyramine in ratsShinya Shibata
Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi, Tokyo 186 8650, Japan
Life Sci 80:546-53. 2007..These results suggest that cholestyramine up-regulates the expression of CYP7A1 independently via LXR- or FXR-mediated pathways in rats... - Hypocholesterolemic mechanism of Chlorella: Chlorella and its indigestible fraction enhance hepatic cholesterol catabolism through up-regulation of cholesterol 7alpha-hydroxylase in ratsShinya Shibata
Yakult Central Institute for Microbiological Research, Tokyo, Japan
Biosci Biotechnol Biochem 71:916-25. 2007..These results suggest that the hypocholesterolemic effect of CP involves enhancement of cholesterol catabolism through up-regulation of hepatic CYP7A1 expression and that CIF contributes to the hypocholesterolemic effect...