Yukari Egashira

Summary

Affiliation: Chiba University
Country: Japan

Publications

  1. ncbi request reprint Differential effects of dietary fatty acids on rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity and gene expression
    Yukari Egashira
    Graduate School of Science and Technology, Chiba University, 648 Matsudo, Chiba 271 8510, Japan
    Biochim Biophys Acta 1686:118-24. 2004
  2. ncbi request reprint Dietary protein level and dietary interaction affect quinolinic acid concentration in rats
    Yukari Egashira
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo 271 8510, Japan
    Int J Vitam Nutr Res 77:142-8. 2007
  3. ncbi request reprint Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis
    Yukari Egashira
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo shi, Chiba 271 8510, Japan
    Int J Vitam Nutr Res 76:28-33. 2006
  4. ncbi request reprint Effect of dietary fiber in edible seaweeds on the development of D-galactosamine-induced hepatopathy in rats
    Naoko Kawano
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Japan
    J Nutr Sci Vitaminol (Tokyo) 53:446-50. 2007
  5. ncbi request reprint Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway
    Yukari Egashira
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo 271 8510, Japan
    Int J Vitam Nutr Res 76:138-46. 2006
  6. ncbi request reprint Mechanism of the suppression against D-galactosamine-induced hepatic injury by dietary amino acids in rats
    Torai Komano
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudoshi, 271 8510 Chiba, Japan
    Amino Acids 37:239-47. 2009
  7. ncbi request reprint Effect of dietary phytol on the expression of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism, in rats
    Hiroko Matsuda
    Laboratory of Food and Nutrition, Graduate School of Horticulture, Chiba University, Matsudo, Chiba 271 8510, Japan
    Biosci Biotechnol Biochem 77:1416-9. 2013
  8. ncbi request reprint Expression of rat hepatic 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase is affected by a high protein diet and by streptozotocin-induced diabetes
    Atsushi Tanabe
    Graduate School of Science and Technology, Chiba University, 648 Matsudo, Chiba 271 8510, Japan
    J Nutr 132:1153-9. 2002
  9. ncbi request reprint Suppressive effect of modified arabinoxylan from rice bran (MGN-3) on D-galactosamine-induced IL-18 expression and hepatitis in rats
    Surina Zheng
    Laboratory of Food and Nutrition, Graduate School of Horticulture, Chiba University, Matsudo, Chiba, Japan
    Biosci Biotechnol Biochem 76:942-6. 2012
  10. ncbi request reprint Effects of various kinds of edible seaweeds in diets on the development of D-galactosamine-induced hepatopathy in rats
    Naoko Kawano
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Chiba, Japan
    J Nutr Sci Vitaminol (Tokyo) 53:315-23. 2007

Detail Information

Publications30

  1. ncbi request reprint Differential effects of dietary fatty acids on rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity and gene expression
    Yukari Egashira
    Graduate School of Science and Technology, Chiba University, 648 Matsudo, Chiba 271 8510, Japan
    Biochim Biophys Acta 1686:118-24. 2004
    ..Moreover, this study provides the information that a high polyunsaturated fatty acid diet affects the production of quinolinic acid in serum by suppressing the ACMSD activity...
  2. ncbi request reprint Dietary protein level and dietary interaction affect quinolinic acid concentration in rats
    Yukari Egashira
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo 271 8510, Japan
    Int J Vitam Nutr Res 77:142-8. 2007
    ..8209, p < 0.01). Increased serum QA concentrations are probably due to a decreased ACMSD activity...
  3. ncbi request reprint Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis
    Yukari Egashira
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo shi, Chiba 271 8510, Japan
    Int J Vitam Nutr Res 76:28-33. 2006
    ..The role of kidney ACMSD activity may be minimal concerning tryptophan-niacin conversion under this experimental condition...
  4. ncbi request reprint Effect of dietary fiber in edible seaweeds on the development of D-galactosamine-induced hepatopathy in rats
    Naoko Kawano
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Japan
    J Nutr Sci Vitaminol (Tokyo) 53:446-50. 2007
    ..These results suggest that the protective effect of the three kinds of brown seaweeds Laminaria sp., Sargassum fulvellum and Eisenia bicyclis against D-GalN-hepatopathy was caused at least in part by fucoidan...
  5. ncbi request reprint Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway
    Yukari Egashira
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo 271 8510, Japan
    Int J Vitam Nutr Res 76:138-46. 2006
    ..However, pyrazinamide does not affect the transcription level of hepatic ACMSD...
  6. ncbi request reprint Mechanism of the suppression against D-galactosamine-induced hepatic injury by dietary amino acids in rats
    Torai Komano
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudoshi, 271 8510 Chiba, Japan
    Amino Acids 37:239-47. 2009
    ..In conclusion, the suppressive effects of amino acids on D-GalN-induced hepatitis were suggested not to be always mediated by the inhibition of Kupffer cells --> TNF-alpha --> apoptosis pathway...
  7. ncbi request reprint Effect of dietary phytol on the expression of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism, in rats
    Hiroko Matsuda
    Laboratory of Food and Nutrition, Graduate School of Horticulture, Chiba University, Matsudo, Chiba 271 8510, Japan
    Biosci Biotechnol Biochem 77:1416-9. 2013
    ..Phytol increased the blood NAD level by suppressing ACMSD mRNA expression in the liver of the rats. It is possible that this mechanism occurred by the activation of PPARα and also of other transcriptional factors. ..
  8. ncbi request reprint Expression of rat hepatic 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase is affected by a high protein diet and by streptozotocin-induced diabetes
    Atsushi Tanabe
    Graduate School of Science and Technology, Chiba University, 648 Matsudo, Chiba 271 8510, Japan
    J Nutr 132:1153-9. 2002
    ..These results indicated that the fluctuation of hepatic ACMSD mRNA expression was followed by that of ACMSD activity...
  9. ncbi request reprint Suppressive effect of modified arabinoxylan from rice bran (MGN-3) on D-galactosamine-induced IL-18 expression and hepatitis in rats
    Surina Zheng
    Laboratory of Food and Nutrition, Graduate School of Horticulture, Chiba University, Matsudo, Chiba, Japan
    Biosci Biotechnol Biochem 76:942-6. 2012
    ..The results suggest that MGN-3 and LMW could provide significant protection against D-GalN liver injury, and that IL-18 might be involved in their protective influence...
  10. ncbi request reprint Effects of various kinds of edible seaweeds in diets on the development of D-galactosamine-induced hepatopathy in rats
    Naoko Kawano
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Chiba, Japan
    J Nutr Sci Vitaminol (Tokyo) 53:315-23. 2007
    ..on D-GalN-hepatopathy in rats is related to GSH metabolism in the intestine...
  11. doi request reprint Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats
    Naho Sasaki
    Graduate School of Horticulture, Chiba University, 648 Mastudo, Mastudo shi, Chiba 2718510, Japan
    Eur J Nutr 48:145-53. 2009
    ..However, the states of these metabolites in diabetes have not been clarified enough yet...
  12. ncbi request reprint Dietary linoleic acid suppresses gene expression of rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) and increases quinolinic acid in serum
    Yukari Egashira
    Laboratory of Food and Nutrition, Department of Bioproduction Science, Chiba University, Matsudo, Chiba 271 8510, Japan
    Adv Exp Med Biol 527:671-4. 2003
    ....
  13. ncbi request reprint Protection by dietary Spirulina platensis against D-galactosamine--and acetaminophen-induced liver injuries
    Jun Lu
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo, Chiba, Japan
    Br J Nutr 103:1573-6. 2010
    ..These results showed that dietary S. platensis could provide a significant protection against d-GalN- and APAP-induced liver injuries, and IL-18 and lipid peroxidation might be involved in the protective influence of S. platensis...
  14. ncbi request reprint Ferulic acid is quickly absorbed from rat stomach as the free form and then conjugated mainly in liver
    Zhaohui Zhao
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
    J Nutr 134:3083-8. 2004
    ..For example, oral administration of FA in capsule form or in a form bonded with sugar esters may provide a more appropriate concentration of FA in the circulation, which may improve its proposed efficacy in preventing chronic disease...
  15. ncbi request reprint Digestion and absorption of ferulic acid sugar esters in rat gastrointestinal tract
    Zhaohui Zhao
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
    J Agric Food Chem 51:5534-9. 2003
    ..Such microbial degradation may be an important factor affecting the bioavailability of dietary FA...
  16. ncbi request reprint Phenolic antioxidants richly contained in corn bran are slightly bioavailable in rats
    Zhaohui Zhao
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
    J Agric Food Chem 53:5030-5. 2005
    ....
  17. doi request reprint L-Gln and L-Ser suppress the D-galactosamine-induced IL-18 expression and hepatitis
    Torai Komano
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
    Biochem Biophys Res Commun 372:688-90. 2008
    ..These results suggest that suppressive effects of some dietary amino acids on the GalN-induced hepatitis are mediated by IL-18 reduction...
  18. doi request reprint Protective effect of low molecular fraction of MGN-3, a modified arabinoxylan from rice bran, on acute liver injury by inhibition of NF-κB and JNK/MAPK expression
    Surina Zheng
    Laboratory of Food and Nutrition, Graduate School of Horticulture, Chiba University, 648 Matsudo, Matsudo shi, Chiba 271 8510, Japan
    Int Immunopharmacol 14:764-9. 2012
    ..These results suggest that the suppressive effects of LMW on GalN-induced hepatitis are possibly related to inhibition of NF-κB, JNK phosphorylation and CD14 expression...
  19. doi request reprint Down-regulation of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase by polyunsaturated fatty acids in hepatocytes is not mediated by PPARalpha
    Naho Sasaki
    Graduate School of Science and Technology, Chiba University, 648 Mastudo, Mastudo shi, Chiba 271 8510, Japan
    Eur J Nutr 47:80-6. 2008
    ....
  20. pmc Purification and molecular cloning of rat 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
    Atsushi Tanabe
    Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 8510, Japan
    Biochem J 361:567-75. 2002
    ..The distribution of ACMSD mRNA expression in various tissues was investigated in the rat by RT-PCR. ACMSD was expressed in the liver and kidney, but not in the other principal organs examined...
  21. ncbi request reprint Suppressive effect of corn bran hemicellulose on liver injury induced by D-galactosamine in rats
    Ayako Daizo
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Chiba, Japan
    Nutrition 21:1044-51. 2005
    ..This study examined the effect of water-soluble corn bran hemicellulose (CBH) on the development of D-galactosamine (GalN) hepatitis in rats to obtain some knowledge about new functions of dietary fiber...
  22. pmc Purification and characterization of a feruloyl esterase from the intestinal bacterium Lactobacillus acidophilus
    Xiaokun Wang
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, Matsudo, Chiba 271 0082, Japan
    Appl Environ Microbiol 70:2367-72. 2004
    ..Moreover, it released two times more FA from FAXX in the presence of added xylanase...
  23. ncbi request reprint Protective effect of red-stemmed type of Ipomoea aquatica Forsk against CCl4-induced oxidative damage in mice
    Shizuka Hirai
    Laboratory of Food and Nutrition, Division of Applied Biological Chemistry, Graduate School of Horticulture, Chiba University, Matsudo, Chiba, Japan
    J Nutr Sci Vitaminol (Tokyo) 57:306-10. 2011
    ..Such effective components in the red type would be beneficial phytochemicals for suppressing several diseases related to oxidative stress...
  24. ncbi request reprint Ferulic acid sugar esters are recovered in rat plasma and urine mainly as the sulfoglucuronide of ferulic acid
    Zhaohui Zhao
    Laboratory of Food and Nutrition, Graduate School of Science and Technology, Chiba University, 648 Matsudo, Matsudo, Chiba 271 0082, Japan
    J Nutr 133:1355-61. 2003
    ..Thus, the physiological functions of FA and its sugar esters found in vitro might require reconsideration in vivo...
  25. ncbi request reprint Regulation of rat hepatic α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme in the tryptophan-NAD pathway, by dietary cholesterol and sterol regulatory element-binding protein-2
    Hiroko Matsuda
    Laboratory of Food and Nutrition, Graduate School of Horticulture, Chiba University, 648 Matsudo, Matsudo, Chiba, 271 8510, Japan
    Eur J Nutr 53:469-77. 2014
    ..The present study was performed to make clear the relationship between ACMSD and cholesterol metabolism using hypercholesterolemic rats and rat primary hepatocytes...
  26. ncbi request reprint Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis"
    Shin Ichi Fukuoka
    Graduate School of Agriculture, Kyoto University, Uji, Kyoto 611 0011, Japan
    J Biol Chem 277:35162-7. 2002
    ..This suggests that a pathway does exist by which the levels of quinolinate in the brain are regulated. In this report, we address the molecular basis underlying quinolinate metabolism and the regulation of ACMSD expression...
  27. ncbi request reprint Hypocholesterolemic mechanism of Chlorella: Chlorella and its indigestible fraction enhance hepatic cholesterol catabolism through up-regulation of cholesterol 7alpha-hydroxylase in rats
    Shinya Shibata
    Yakult Central Institute for Microbiological Research, Tokyo, Japan
    Biosci Biotechnol Biochem 71:916-25. 2007
    ..These results suggest that the hypocholesterolemic effect of CP involves enhancement of cholesterol catabolism through up-regulation of hepatic CYP7A1 expression and that CIF contributes to the hypocholesterolemic effect...
  28. ncbi request reprint Identification and expression of alpha cDNA encoding human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD): a key enzyme for the tryptophan-niacine pathway and quinolinate hypothesis
    Shin Ichi Fukuoka
    Graduate School of Agriculuture, Kyoto University, Uji, Kyoto 611 0011, Japan
    Adv Exp Med Biol 527:443-53. 2003
    ..This suggests that a pathway does exist by which the levels of quinolinate in the brain are regulated. In this report, we address the molecular basis underlying quinolinate metabolism and the regulation of ACMSD expression...
  29. ncbi request reprint Effects of dietary corn bran hemicellulose and neomycin on hepatic caspase-3 activity and glycoprotein concentration in rats treated with or without D-galactosamine
    Ayako Daizo
    Seitoku University, Chiba, Japan
    J Nutr Sci Vitaminol (Tokyo) 52:96-104. 2006
    ....
  30. ncbi request reprint Roles of nuclear receptors in the up-regulation of hepatic cholesterol 7alpha-hydroxylase by cholestyramine in rats
    Shinya Shibata
    Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi, Tokyo 186 8650, Japan
    Life Sci 80:546-53. 2007
    ..These results suggest that cholestyramine up-regulates the expression of CYP7A1 independently via LXR- or FXR-mediated pathways in rats...