Hiroji Chibana

Summary

Affiliation: Chiba University
Country: Japan

Publications

  1. ncbi request reprint [Genomic analysis in Candida albicans]
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba, 260 8673, Japan
    Nihon Ishinkin Gakkai Zasshi 44:81-5. 2003
  2. ncbi request reprint Mutation in IRO1 tightly linked with URA3 gene reduces virulence of Candida albicans
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba, Japan
    Microbiol Immunol 49:937-9. 2005
  3. pmc Intestinal resident yeast Candida glabrata requires Cyb2p-mediated lactate assimilation to adapt in mouse intestine
    Keigo Ueno
    Medical Mycology Research Center MMRC, Chiba University, Chiba, Japan
    PLoS ONE 6:e24759. 2011
  4. doi request reprint The enigma of the major repeat sequence of Candida albicans
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1 8 1 Inohana, Chiba 260 8673, Japan
    Future Microbiol 4:171-9. 2009
  5. pmc Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba 260 8673, Japan
    Genetics 170:1525-37. 2005
  6. ncbi request reprint Nocardia concava sp. nov., isolated from Japanese patients
    Akiko Kageyama
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chuo Ku, Chiba 260 8673, Japan
    Int J Syst Evol Microbiol 55:2081-3. 2005
  7. doi request reprint Differential cell wall remodeling of two chitin synthase deletants Δchs3A and Δchs3B in the pathogenic yeast Candida glabrata
    Keigo Ueno
    Medical Mycology Research Center, Chiba University, Chuo Ku, Japan
    FEMS Yeast Res 11:398-407. 2011
  8. pmc Development of a highly efficient gene targeting system induced by transient repression of YKU80 expression in Candida glabrata
    Keigo Ueno
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1 8 1 Inohana, Chiba 260 8673, Japan
    Eukaryot Cell 6:1239-47. 2007
  9. ncbi request reprint [Structural and functional analyses of MRS (major repeated sequnece) in Candida albicans. Application for genotyping and the eternal way to the complete genome sequence]
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan
    Nihon Ishinkin Gakkai Zasshi 47:129-34. 2006
  10. doi request reprint Scanning and negative-staining electron microscopy of protoplast regeneration of a wild-type and two chitin synthase mutants in the pathogenic yeast Candida glabrata
    Yuichi Namiki
    Medical Mycology Research Center, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8673, Japan
    J Electron Microsc (Tokyo) 60:157-65. 2011

Collaborators

Detail Information

Publications21

  1. ncbi request reprint [Genomic analysis in Candida albicans]
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba, 260 8673, Japan
    Nihon Ishinkin Gakkai Zasshi 44:81-5. 2003
    ..From these, we present the history and current status of the genomic analysis of Candida albicans. The sequencing project for this organism has been undertaken at Stanford University, and is now nearing the end...
  2. ncbi request reprint Mutation in IRO1 tightly linked with URA3 gene reduces virulence of Candida albicans
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba, Japan
    Microbiol Immunol 49:937-9. 2005
    ..The IRO1 gene adjacent to URA3 was inadvertently deleted during construction of CAI4. We report here that a mutation in IRO1 reduces virulence of C. albicans...
  3. pmc Intestinal resident yeast Candida glabrata requires Cyb2p-mediated lactate assimilation to adapt in mouse intestine
    Keigo Ueno
    Medical Mycology Research Center MMRC, Chiba University, Chiba, Japan
    PLoS ONE 6:e24759. 2011
    ..From those results, we conclude that Cyb2p-mediated lactate assimilation is an intestinal adaptation factor of C. glabrata...
  4. doi request reprint The enigma of the major repeat sequence of Candida albicans
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1 8 1 Inohana, Chiba 260 8673, Japan
    Future Microbiol 4:171-9. 2009
    ..The polymorphism of the major repeat sequence has been exploited in epidemiology and taxonomic studies. This review describes its sequence, occurrence, use in epidemiology and examines the evidence for its role in chromosome dynamics...
  5. pmc Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba 260 8673, Japan
    Genetics 170:1525-37. 2005
    ..Synteny analysis revealed that the degree of synteny between C. albicans and Saccharomyces cerevisiae is too weak to use for completion of the genomic sequence in C. albicans...
  6. ncbi request reprint Nocardia concava sp. nov., isolated from Japanese patients
    Akiko Kageyama
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chuo Ku, Chiba 260 8673, Japan
    Int J Syst Evol Microbiol 55:2081-3. 2005
    ..seriolae indicated that the strains belong to a novel species of Nocardia, for which the name Nocardia concava sp. nov. is proposed. The type strain is IFM 0354(T) (=NBRC 100430(T)=JCM 12351(T)=DSM 44804(T))...
  7. doi request reprint Differential cell wall remodeling of two chitin synthase deletants Δchs3A and Δchs3B in the pathogenic yeast Candida glabrata
    Keigo Ueno
    Medical Mycology Research Center, Chiba University, Chuo Ku, Japan
    FEMS Yeast Res 11:398-407. 2011
    ....
  8. pmc Development of a highly efficient gene targeting system induced by transient repression of YKU80 expression in Candida glabrata
    Keigo Ueno
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1 8 1 Inohana, Chiba 260 8673, Japan
    Eukaryot Cell 6:1239-47. 2007
    ..However, the levels of mRNA transcription were restored and no difference in the survival ratio in vivo compared to that with the YKU80 wild-type strain was identified...
  9. ncbi request reprint [Structural and functional analyses of MRS (major repeated sequnece) in Candida albicans. Application for genotyping and the eternal way to the complete genome sequence]
    Hiroji Chibana
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan
    Nihon Ishinkin Gakkai Zasshi 47:129-34. 2006
    ..albicans chromosome loss events and associated phenotypic changes. Here we summarize structural analyses from subrepeat sequences to the chromosome level, and functional analyses of MRS...
  10. doi request reprint Scanning and negative-staining electron microscopy of protoplast regeneration of a wild-type and two chitin synthase mutants in the pathogenic yeast Candida glabrata
    Yuichi Namiki
    Medical Mycology Research Center, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8673, Japan
    J Electron Microsc (Tokyo) 60:157-65. 2011
    ..These results suggest that CHS3A and CHS3B genes may have important roles in cell wall formation during protoplast regeneration, but can be compensated by other cell wall enzymes...
  11. doi request reprint Target validation and ligand development for a pathogenic fungal profilin, using a knock-down strain of pathogenic yeast Candida glabrata and structure-based ligand design
    Keigo Ueno
    Medical Mycology Research Center MMRC, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8673, Japan
    Yeast 27:369-78. 2010
    ..Hence, we show here that profilin is a potential antifungal target and offer novel peptide ligands...
  12. ncbi request reprint Genotyping of fluconazole-resistant Candida albicans isolated from Uighurian people in Xinjing (China) using ALTS/RFLP and micro-TGGE method
    Juhaer Mijiti
    Medical Mycology Research Center, Chiba University, Chiba, Japan
    Nihon Ishinkin Gakkai Zasshi 51:165-8. 2010
    ..albicans tandem repeating units (ALTS)/RFLP and micro-temperature gradient gel electrophoresis (micro-TGGE). This new method was able to distinguish all seven strains. A suspected nosocomial infection was ruled out...
  13. ncbi request reprint Gordonia otitidis sp. nov., isolated from a patient with external otitis
    Soji Iida
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chuo Ku, Chiba 260 8673, Japan
    Int J Syst Evol Microbiol 55:1871-6. 2005
    ..The name proposed for this taxon is Gordonia otitidis sp. nov.; the type strain is IFM 10032(T) (=DSM 44809(T)=JCM 12355(T)=NBRC 100426(T))...
  14. ncbi request reprint Genotyping of Candida albicans on the basis of polymorphisms of ALT repeats in the repetitive sequence (RPS)
    Takako Iwata
    Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Nagoya shi, Aichi 466 8550, Japan
    J Dermatol Sci 41:43-54. 2006
    ..Candida albicans is one of the most important etiologic agents causing superficial and deep fungal infections. For prevention of candidiasis, it is important to develop a rapid system that discriminates C. albicans at the strain level...
  15. ncbi request reprint Transcriptional profiling of the early stages of germination in Candida albicans by real-time RT-PCR
    Mika Toyoda
    Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College, Fukuoka 814 0193, Japan
    FEMS Yeast Res 5:287-96. 2004
    ..Both EFG1 and NRG1 were similarly expressed under hypha-inducing conditions and heat shock. Expression of TUP1 was slightly different from the expression of EFG1 or NRG1...
  16. pmc Effect of the major repeat sequence on chromosome loss in Candida albicans
    Paul R Lephart
    Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Eukaryot Cell 4:733-41. 2005
    ..This effect on chromosome segregation is the first demonstration of a phenotype associated with the MRS...
  17. pmc Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes
    Marco van het Hoog
    Biotechnology Research Institute, National Research Council of Canada, Montreal, Quebec, Canada
    Genome Biol 8:R52. 2007
    ..However, sequences of specific chromosomes were not determined...
  18. ncbi request reprint Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium
    Tamaki Cho
    Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College, 2 15 1 Tamura, Sawara ku, Fukuoka 814 0193, Japan
    Nihon Ishinkin Gakkai Zasshi 48:159-67. 2007
    ..albicans following its internalization by phagocyte cells and adaptation to host challenges...
  19. ncbi request reprint The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum
    Hironobu Nakayama
    Department of Chemistry and Biochemistry, Suzuka National College of Technology, Shiroko, Suzuka, Mie 510 0294, Japan
    J Antimicrob Chemother 60:1264-72. 2007
    ..The uptake of endogenous sterol from serum may allow Candida glabrata to survive azole treatment. This study aims to determine the contribution of a sterol transporter that alters fluconazole sensitivity in the presence of serum...
  20. pmc The diploid genome sequence of Candida albicans
    Ted Jones
    Stanford Genome Technology Center, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 101:7329-34. 2004
    ..We provide a whole-genome description of heterozygosity in the organism. Comparative genomic analyses provide important clues about the evolution of the species and its mechanisms of pathogenesis...
  21. ncbi request reprint [Quorum-sensing system in Candida albicans]
    Tamaki Cho
    Section of Infection Biology, Fukuoka Dental College, Japan
    Nihon Ishinkin Gakkai Zasshi 47:263-8. 2006
    ..Candida albicans has been shown to form biofilm on many medical devices, therefore quorum-sensing in this organism has been especially focused on from the aspect of biofilm formation...