Yasunori Akutsu

Summary

Affiliation: Chiba University
Country: Japan

Publications

  1. doi request reprint Impact of preoperative dental plaque culture for predicting postoperative pneumonia in esophageal cancer patients
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Dig Surg 25:93-7. 2008
  2. pmc Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens
    Koji Kono
    First Department of Surgery, University of Yamanashi, Yamanashi, Japan
    J Transl Med 10:141. 2012
  3. doi request reprint Lymph node dissection for esophageal cancer
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1, Inohana, Chuo Ku, Chiba 260 8670, Japan
    Gen Thorac Cardiovasc Surg 61:397-401. 2013
  4. doi request reprint The overall prevalence of metastasis in T1 esophageal squamous cell carcinoma: a retrospective analysis of 295 patients
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Japan
    Ann Surg 257:1032-8. 2013
  5. doi request reprint S-1 monotherapy as second- or third-line chemotherapy for unresectable and recurrent esophageal squamous cell carcinoma
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba 260 8670, Japan
    Oncology 84:305-10. 2013
  6. ncbi request reprint A phase 1/11 study of second-line chemotherapy with fractionated docetaxel and nedaplatin for 5-FU/cisplatin-resistant esophageal squamous cell carcinoma
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Hepatogastroenterology 59:2095-8. 2012
  7. doi request reprint Are additional trace elements necessary in total parenteral nutrition for patients with esophageal cancer receiving cisplatin-based chemotherapy?
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1, Inohana, Chuo Ku, Chiba, 260 8670, Japan
    Biol Trace Elem Res 150:109-15. 2012
  8. doi request reprint The number of pathologic lymph nodes involved is still a significant prognostic factor even after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Inohana, Chuo Ku, Chiba, Japan
    J Surg Oncol 105:756-60. 2012
  9. doi request reprint A phase I/II clinical trial of preoperative short-course carbon-ion radiotherapy for patients with squamous cell carcinoma of the esophagus
    Yasunori Akutsu
    Investigators of the Working Group for Gastrointestinal Tumors, Chiba, Japan
    J Surg Oncol 105:750-5. 2012
  10. pmc Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology
    Hideaki Tahara
    Department of Surgery and Bioengineering, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    J Transl Med 7:45. 2009

Collaborators

Detail Information

Publications52

  1. doi request reprint Impact of preoperative dental plaque culture for predicting postoperative pneumonia in esophageal cancer patients
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Dig Surg 25:93-7. 2008
    ..We evaluated the interaction between preoperative dental plaque and postoperative pneumonia in patients undergoing esophagectomy...
  2. pmc Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens
    Koji Kono
    First Department of Surgery, University of Yamanashi, Yamanashi, Japan
    J Transl Med 10:141. 2012
    ....
  3. doi request reprint Lymph node dissection for esophageal cancer
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1, Inohana, Chuo Ku, Chiba 260 8670, Japan
    Gen Thorac Cardiovasc Surg 61:397-401. 2013
    ..In this article, recent literatures were reviewed and we discuss the current status of lymph node dissection in EC. ..
  4. doi request reprint The overall prevalence of metastasis in T1 esophageal squamous cell carcinoma: a retrospective analysis of 295 patients
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Japan
    Ann Surg 257:1032-8. 2013
    ..To achieve successful treatment by EMR/ESD, the risk of LN metastases, LN recurrence, and hematological recurrence need to be better understood. The aim of this study was to determine the precise risk for metastasis in T1 ESCC...
  5. doi request reprint S-1 monotherapy as second- or third-line chemotherapy for unresectable and recurrent esophageal squamous cell carcinoma
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba 260 8670, Japan
    Oncology 84:305-10. 2013
    ..It may be useful for esophageal squamous cell carcinoma (ESCC); however, there are insufficient data. The purpose is to provide results of an analysis of S-1 monotherapy for unresectable and recurrent ESCC...
  6. ncbi request reprint A phase 1/11 study of second-line chemotherapy with fractionated docetaxel and nedaplatin for 5-FU/cisplatin-resistant esophageal squamous cell carcinoma
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Hepatogastroenterology 59:2095-8. 2012
    ..There are few second-line regimens available for esophageal cancer. The use of fractionated docetaxel and nedaplatin as second-line chemotherapy was examined in this study...
  7. doi request reprint Are additional trace elements necessary in total parenteral nutrition for patients with esophageal cancer receiving cisplatin-based chemotherapy?
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1, Inohana, Chuo Ku, Chiba, 260 8670, Japan
    Biol Trace Elem Res 150:109-15. 2012
    ..TPN with supplementary trace elements is preferable and recommended for patients who are undergoing chemotherapy in order to maintain the patients' nutrient homeostasis...
  8. doi request reprint The number of pathologic lymph nodes involved is still a significant prognostic factor even after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Inohana, Chuo Ku, Chiba, Japan
    J Surg Oncol 105:756-60. 2012
    ..We evaluated the correlation between the number of pathologic metastatic lymph nodes (LNs) and the surgical outcome in ESCC after NACRT...
  9. doi request reprint A phase I/II clinical trial of preoperative short-course carbon-ion radiotherapy for patients with squamous cell carcinoma of the esophagus
    Yasunori Akutsu
    Investigators of the Working Group for Gastrointestinal Tumors, Chiba, Japan
    J Surg Oncol 105:750-5. 2012
    ..Carbon-ion radiotherapy (CIR) has been under development. We report the results of a phase I/II clinical trial of preoperative CIR for esophageal squamous cell carcinoma (ESCC)...
  10. pmc Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology
    Hideaki Tahara
    Department of Surgery and Bioengineering, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    J Transl Med 7:45. 2009
    ..The institution of an interactive consortium for high throughput molecular monitoring of clinical trials with voluntary participation might provide cost-effective solutions...
  11. ncbi request reprint Combination of direct intratumoral administration of dendritic cells and irradiation induces strong systemic antitumor effect mediated by GRP94/gp96 against squamous cell carcinoma in mice
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Int J Oncol 31:509-15. 2007
    ..Gp96 is thought to be one of the target molecules to explain the abscopal effect...
  12. doi request reprint COX2 expression predicts resistance to chemoradiotherapy in esophageal squamous cell carcinoma
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Ann Surg Oncol 18:2946-51. 2011
    ..The purpose of the present study was to evaluate whether COX2 expression is an indicator of resistance to chemoradiotherapy in esophageal squamous cell carcinoma and the feasibility of COX2 as a biomarker for CRT...
  13. doi request reprint Pre-operative dental brushing can reduce the risk of postoperative pneumonia in esophageal cancer patients
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Surgery 147:497-502. 2010
    ..The effectiveness of pre-operative dental brushing to decrease the risk of postoperative pneumonia in esophageal cancer patients was evaluated prospectively...
  14. doi request reprint Correlation between gp96 expression and the surgical outcome in patients with esophageal squamous cell carcinoma
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Ann Surg Oncol 18:832-7. 2011
    ..Gp96 has a close relationship with antitumor immunity. This study evaluated the correlation between gp96 expression and the prognosis in esophageal squamous cell carcinoma...
  15. ncbi request reprint Endoscope-assisted thoracoscopic technique for esophageal bronchogenic cyst which presented elevated CA125
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Dig Surg 23:209-14. 2006
    ..8 U/ml and intratumoral CA125 concentration was 1,690,000 U/ml. Serum CA125 decreased to 16.5 U/ml after surgery. In this paper, we present a new strategy of the treatment for bronchogenic cyst and a review the literature...
  16. ncbi request reprint Gene expression profiling induced by histone deacetylase inhibitor, FK228, in human esophageal squamous cancer cells
    Isamu Hoshino
    Department of Frontier Surgery, Chiba University, Graduate School of Medicine, Chiba 260 8670, Japan
    Oncol Rep 18:585-92. 2007
    ..These observations of the expression patterns of functionally classified genes provided insights into the mechanism of the antitumor effect of FK228 in esophageal squamous carcinoma...
  17. ncbi request reprint Effects of carbon-ion radiotherapy combined with a novel histone deacetylase inhibitor, cyclic hydroxamic-acid-containing peptide 31 in human esophageal squamous cell carcinoma
    Masayuki Kano
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chuoku, Chiba 260 0856, Japan
    Anticancer Res 29:4433-8. 2009
    ..Several studies have evaluated the combination of X-rays and HDACIs, but, to date, no study has evaluated carbon-ion radiotherapy combined with HDACIs...
  18. doi request reprint Combined effects of p53 gene therapy and leptomycin B in human esophageal squamous cell carcinoma
    Isamu Hoshino
    Department of Frontier Surgery, Chiba University, Graduate School of Medicine, Chiba, Japan
    Oncology 75:113-9. 2008
    ..Currently, it has been shown that p53 protein has a nuclear export signal. In this study, we assessed whether LMB augments the transduced p53 gene effect...
  19. ncbi request reprint Have surgical outcomes of pathologic T4 esophageal squamous cell carcinoma really improved? Analysis of 268 cases during 45 years of experience
    Hideaki Shimada
    Department of Frontier Surgery and the Research Center for Frontier Medical Engineering, Chiba University Graduate School of Medicine, Chiba, Japan
    J Am Coll Surg 206:48-56. 2008
    ....
  20. doi request reprint The molecular role of Fra-1 and its prognostic significance in human esophageal squamous cell carcinoma
    Akihiro Usui
    Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
    Cancer 118:3387-96. 2012
    ..The authors investigated the significance of Fra-1 expression in esophageal squamous cell carcinoma (ESCC) and studied the effect of its down-regulation on cell proliferation, motility, and invasion...
  21. doi request reprint Identification of novel molecular targets regulated by tumor suppressive miR-375 induced by histone acetylation in esophageal squamous cell carcinoma
    Yuka Isozaki
    Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
    Int J Oncol 41:985-94. 2012
    ..Our results indicate that HDACIs upregulate miRNAs, at least some of which act as tumor suppressors. LDHB, which is regulated by the tumor suppressive miR-375, may therefore act as an oncogene in ESCC...
  22. ncbi request reprint Tumor suppressor Prdx1 is a prognostic factor in esophageal squamous cell carcinoma patients
    Isamu Hoshino
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba 260 8670, Japan
    Oncol Rep 18:867-71. 2007
    ..Our results provide strong evidence that the reduced Prdx1 expression is an important factor in esophageal squamous cancer progression and could serve as a useful prognostic marker...
  23. ncbi request reprint Role of histone deacetylase inhibitor in adenovirus-mediated p53 gene therapy in esophageal cancer
    Isamu Hoshino
    Department of Frontier Surgery, Chiba University, Graduate School of Medicine, Chiba 260 8670, Japan
    Anticancer Res 28:665-71. 2008
    ..The effectiveness of one of the novel HDACIs, FK228, was examined in adenovirus-mediated p53 gene therapy of esophageal squamous cell carcinoma (ESCC)...
  24. ncbi request reprint Surgical outcome after the clearance of abdominal metastatic lymph nodes in 138 patients with thoracic esophageal carcinoma
    Hideaki Shimada
    Department of Frontier Surgery M9, Chiba University, Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Am J Surg 193:448-52; discussion 453. 2007
    ..The purpose of this study was to evaluate the patients' surgical outcome after the clearance of metastatic abdominal nodes...
  25. doi request reprint Clinical and pathologic evaluation of the effectiveness of neoadjuvant chemoradiation therapy in advanced esophageal cancer patients
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1, Inohana, Chuo Ku, Chiba 260 8670, Japan
    World J Surg 33:1002-9. 2009
    ..The aim of this study was to clarify when a decision can be made to perform further treatment for a clinical CR...
  26. doi request reprint CHAP31 induces apoptosis only via the intrinsic pathway in human esophageal cancer cells
    Kentaro Murakami
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan matsuhm faculty chiba u jp
    Oncology 78:62-74. 2010
    ..This study describes the antiproliferative activity of CHAP31, a novel HDAC inhibitor. Furthermore, the molecular mechanism of CHAP31-induced apoptosis was investigated in ESCC...
  27. ncbi request reprint Location and clinical impact of solitary lymph node metastasis in patients with thoracic esophageal carcinoma
    Hideaki Shimada
    Department of Frontier Surgery, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuou ku, Chiba 260 8677, Japan
    Am J Surg 192:306-10. 2006
    ..The location and clinical impact of solitary lymph node metastasis from thoracic esophageal carcinoma have not been evaluated sufficiently...
  28. ncbi request reprint [Evaluation of false-negative lymph nodes diagnosed by fludeoxy glucose-positron emission tomography in cases of metastatic esophageal squamous cell carcinoma]
    Tsuguaki Kono
    Dept of Frontier Surgery, Graduate School of Medicine, Chiba University
    Gan To Kagaku Ryoho 40:2155-7. 2013
    ..The detection of false-negative lymph nodes by FDG-PET was not precise because of increases in the quantity of stroma-like cells in poorly differentiated carcinomas and in fibrosis caused by neoadjuvant therapy in the lymph nodes. ..
  29. ncbi request reprint Surgical outcome of elderly patients 75 years of age and older with thoracic esophageal carcinoma
    Hideaki Shimada
    Department of Frontier Surgery M9, Chiba University, Graduate School of Medicine, 1 8 1 Inohana, Chiba, Japan
    World J Surg 31:773-9. 2007
    ..This study aimed to evaluate the surgical outcome of esophagectomy in patients 75 years of age and older with thoracic esophageal carcinoma...
  30. doi request reprint miR-203 inhibits the migration and invasion of esophageal squamous cell carcinoma by regulating LASP1
    Nobuyoshi Takeshita
    Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
    Int J Oncol 41:1653-61. 2012
    ..The identification of a cancer network regulated by miR-203 could provide new insights into the potential mechanisms of the progression of ESCC...
  31. ncbi request reprint Prediction of lymph node status in patients with superficial esophageal carcinoma: analysis of 160 surgically resected cancers
    Hideaki Shimada
    Department of Frontier Surgery M9, Chiba University, Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Am J Surg 191:250-4. 2006
    ..The ability to predict lymph node metastasis in cases of superficial esophageal carcinoma before surgery would allow the identification of specific patients who do not require additional surgical resection after endoscopic local resection...
  32. ncbi request reprint [A case of far advanced-esophageal squamous cell carcinoma successfully treated with docetaxel]
    Nobuyoshi Takeshita
    Dept of Frontier Surgery, Graduate School of Medicine, Chiba University
    Gan To Kagaku Ryoho 40:233-5. 2013
    ..The patient is doing well without any signs of recurrence 21 months after the surgery...
  33. ncbi request reprint [Effect of practical use of preoperative immunonutrition with impact on prevention of postoperative pneumonia after esophagectomy]
    Masayuki Kano
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University
    Gan To Kagaku Ryoho 36:1958-60. 2009
    ....
  34. ncbi request reprint Long-term results after dissection of positive thoracic lymph nodes in patients with esophageal squamous cell carcinoma
    Hideaki Shimada
    Department of Frontier Surgery, Chiba University, Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba, 260 8670, Japan
    World J Surg 32:255-61. 2008
    ..The purpose of this study was to evaluate surgical outcome after the clearance of metastatic thoracic lymph nodes...
  35. doi request reprint Primary esophageal adenocarcinoma arising from heterotopic gastric mucosa: report of a case
    Naoki Akanuma
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba, Chiba 260 8670, Japan
    Surg Today 43:446-51. 2013
    ..Postoperative chemoradiotherapy was performed because positive surgical margins were observed in the resected tissue. The patient has remained alive for more than 4 years after surgery, without any evidence of recurrence...
  36. ncbi request reprint Is the surgical stress associated with worse survival in patients with esophageal cancer?--Analysis of colon substitution for 37 patients with remnant stomach
    Hideaki Shimada
    Department of Frontier Surgery, Chiba University Graduate School of Medicine, 1 8 1, Inohana, Chuou ku, Chiba 260 8677, Japan
    Hepatogastroenterology 54:791-5. 2007
    ..We evaluated the affect of this surgical stress on the postoperative course and long-term survival of patients with esophageal carcinoma...
  37. ncbi request reprint [Two cases treated with trastuzumab as primary chemotherapy]
    Kentaro Murakami
    Dept of Frontier Surgery, Graduate School of Medicine, Chiba University
    Gan To Kagaku Ryoho 34:1683-7. 2007
    ..Later, because of mild tumor regrowth, we used 2 courses of vinorelbine in combination with trastuzumab. The tumor grew more, so Bp + Ax was done. The woman is alive at this writing with no recurrence...
  38. doi request reprint Perioperative changes of serum p53 antibody titer is a predictor for survival in patients with esophageal squamous cell carcinoma
    Hideaki Shimada
    Department of Gastroenterological Surgery, Chiba Cancer Center, 666 2 Nitona cho, Chuou ku, Chiba, 260 8717, Japan
    World J Surg 33:272-7. 2009
    ....
  39. doi request reprint miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma
    Masayuki Kano
    Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
    Int J Cancer 127:2804-14. 2010
    ..The identification of tumor-suppressive miRNAs, miR-145, miR-133a and miR-133b, directly control oncogenic FSCN1 gene. These signal pathways of ESCC could provide new insights into potential mechanisms of ESCC carcinogenesis...
  40. ncbi request reprint Combinatory gene therapy with electrotransfer of midkine promoter-HSV-TK and interleukin-21
    Naoyuki Hanari
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba, 260 8670, Japan
    Anticancer Res 27:2305-10. 2007
    ..We examined the effect of the combination of herpes simplex virus type1-thymidine kinase (HSV-TK)-suicide gene therapy and interleukin-21 (IL-21) immune gene therapy...
  41. doi request reprint Mode of lymphadenectomy and surgical outcome of upper thoracic esophageal squamous cell carcinoma
    Hideaki Shimada
    Department of Gastroenterological Surgery, Chiba Cancer Center, 666 2 Nitonacho, Chuou ku, Chiba, 260 8717, Japan
    J Gastrointest Surg 13:619-25. 2009
    ..Only a few studies have evaluated the impact of clinicopathological variables and cervical lymphadenectomy on survival in patients with upper thoracic esophageal squamous cell carcinoma (SCC)...
  42. doi request reprint Diffusely infiltrative squamous cell carcinoma of the esophagus presenting as a case with diagnostic difficulty
    Akihiro Usui
    Department of Frontier Surgery, Chiba University Graduate School, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba, Chiba, 260 8670, Japan
    Surg Today 43:794-9. 2013
    ..Despite various treatments, the patient died of disease progression 20 months after its onset. Autopsy revealed diffusely infiltrative squamous cell carcinoma of the esophagus, which is a rare malignancy with few case reports documented...
  43. ncbi request reprint Histone deacetylase inhibitor FK228 activates tumor suppressor Prdx1 with apoptosis induction in esophageal cancer cells
    Isamu Hoshino
    Department of Frontier Surgery M9, Graduate School of Medicine, Chiba University, Japan
    Clin Cancer Res 11:7945-52. 2005
    ..The purpose of this study is to reveal the effect of FK228 on gene expression in the cell and to determine the mechanism of the antitumor activity of FK228 for further clinical applications...
  44. doi request reprint The significance of lymph node status as a prognostic factor for esophageal cancer
    Yasunori Akutsu
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba, 260 8670, Japan
    Surg Today 41:1190-5. 2011
    ..Better knowledge of the N-status is therefore needed to effectively utilize this information. Further research should focus on the N-status of patients with esophageal cancer...
  45. doi request reprint A COX-2 inhibitor enhances the antitumor effects of chemotherapy and radiotherapy for esophageal squamous cell carcinoma
    Gulbostan Yusup
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba 260 8670, Japan
    Int J Oncol 44:1146-52. 2014
    ..In addition, the combination treatment with the COX-2 inhibitor and 5-FU markedly inhibited both the cell invasion and migration activity. Therefore, COX-2 inhibitors can be useful enhancers of antitumor drugs and radiotherapy for ESCC. ..
  46. ncbi request reprint Low peritoneal and systemic inflammatory response after laparoscopy-assisted gastrectomy compared to open gastrectomy
    Toshiyuki Natsume
    Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
    Hepatogastroenterology 58:659-62. 2011
    ..Peritoneal immune response as well as systemic response was objectively evaluated in laparoscopy-assisted distal gastrectomy (LADG) compared to open distal gastrectomy (ODG)...
  47. ncbi request reprint [Diffusion-weighted MR imaging for postoperative nodal recurrence of esophageal squamous cell cancer in comparison with FDG-PET]
    Kiyohiko Shuto
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University
    Gan To Kagaku Ryoho 36:2468-70. 2009
    ..5 revealed 100% overall accuracy for separating the recurrent lesion from normal esophagus. Noninvasive DWIBS may become a valid modality to discriminate nodal recurrence of esophageal cancer by no means inferior to PET...
  48. ncbi request reprint Development of immunostimulatory virotherapy using non-transmissible Sendai virus-activated dendritic cells
    Yasuo Yoneyama
    Department of Gene Therapy, Chiba University, Chiba, Japan Department of Frontier Surgery, Chiba University, Chiba, Japan
    Biochem Biophys Res Commun 355:129-35. 2007
    ..This is the first demonstration that non-transmissible SeV vector, SeV/dF, could be a DC-activator; DC/SeV/dF-based cancer immunotherapy may, therefore, warrant further investigation...
  49. doi request reprint Tracheal compression by the gastric tube in esophageal cancer with ankylosing spondylitis and an analysis of the mediastinal condition in 84 cases of esophagectomy: report a case
    Norimasa Ikeda
    Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Surg Today 43:1071-4. 2013
    ..This case was successfully treated with a mediastinal pleural incision through a right thoracotomy. The distance between the sternum and the vertebra in this case was narrower than normal, thereby inducing this rare condition. ..
  50. ncbi request reprint Impact of lymph node involvement in T2 or T3 thoracic esophageal squamous cell carcinoma
    Hideaki Shimada
    Division of Gastroenterological Surgery, Chiba Cancer Center, 666 2 Nitona Chou, Chuou ku, Chiba 260 8717, Japan
    Hepatogastroenterology 56:1039-43. 2009
    ..Only a few study analyzed the prognostic impact of clinicopathological factors for surgical outcome of patients with esophageal carcinoma focused on T2/T3 tumors...
  51. doi request reprint Preparation and characterization of phospholipid-conjugated indocyanine green as a near-infrared probe
    Akiko Suganami
    Department of Bioinformatics, Graduate School of Medicine, Chiba University, Chiba 260 8670, Japan
    Bioorg Med Chem Lett 22:7481-5. 2012
    ..We also observed the tumor-specific biodistribution of LP-iDOPE of in vivo xenografts. These findings suggest that LP-iDOPE might be a promising tool for NIR optical imaging, photodynamic therapy, and photothermal therapy...
  52. ncbi request reprint Expansion of lung V alpha 14 NKT cells by administration of alpha-galactosylceramide-pulsed dendritic cells
    Yasunori Akutsu
    CREST Core Research for Evolutional Science and Technology Project, JST, Kawaguchi, Saitama 332 0012, Japan
    Jpn J Cancer Res 93:397-403. 2002
    ..The feasibility of immunotherapy with alpha-GalCer-pulsed dendritic cells is discussed...